IEEE Transactions on Radiation and Plasma Medical Sciences最新文献

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Millisecond-Level VMAT Plan Dose Calculation for Cervical Cancer With a Mamba-Based UNet Model 基于曼巴的UNet模型计算宫颈癌的毫秒级VMAT计划剂量
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2026-01-12 DOI: 10.1109/TRPMS.2026.3651299
Wanhua Zhang;Sijuan Huang;Yinda Du;Ruofei Li;Ting Song;Yongbao Li
{"title":"Millisecond-Level VMAT Plan Dose Calculation for Cervical Cancer With a Mamba-Based UNet Model","authors":"Wanhua Zhang;Sijuan Huang;Yinda Du;Ruofei Li;Ting Song;Yongbao Li","doi":"10.1109/TRPMS.2026.3651299","DOIUrl":"https://doi.org/10.1109/TRPMS.2026.3651299","url":null,"abstract":"This study aims to develop a mamba-based UNet model (MambaUNet) for fast and accurate volumetric modulated arc therapy (VMAT) plan dose calculation in cervical cancer. The 2-D fluence maps from all control points were projected into a 3-D fluence volume and combined with the corresponding density volume as input to MambaUNet, which subsequently calculated the 3-D dose distribution. The model integrated volumetric feature extraction via a 3-D residual UNet and efficient global dependency modeling through a mamba encoder. A total of 633 cervical cancer VMAT plans were used, with 445 allocated for training, 128 for validation, and 60 for testing. The MambaUNet model was also comparatively evaluated against three other models (iDoTA, TransUNet, and ResUNet) in terms of dose calculation accuracy and computational efficiency. On the test set, the dose–volume histograms (DVHs), mean absolute errors (MAEs), root-mean-square errors (RMSEs), Dice similarity coefficients (DSCs), and dosimetric indices between the model-calculated doses and the ground-truth doses all demonstrated good agreement. The proposed MambaUNet model achieved an average 3-D gamma passing rate of <inline-formula> <tex-math>$98.79~pm ~0.78$ </tex-math></inline-formula>% under the 3%/2 mm criterion. It provided dose calculation accuracy comparable to or slightly better than the other models and achieved higher computational efficiency. The entire dose calculation process, including fluence map generation from MLC sequences, fluence projection, and MambaUNet model inference, can be completed within 80 ms on average. These results suggest that MambaUNet has strong potential for accelerating the VMAT planning process.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"969-980"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization Study of a Helium Cold Atmospheric-Pressure Plasma Jet and Its Application in Plasma-Mediated Root Canal Irrigation 氦冷常压等离子体射流的表征及其在等离子体介导根管冲洗中的应用研究
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2025-11-04 DOI: 10.1109/TRPMS.2025.3628120
Abhijit Mishra;Sushma Jangra;Ritesh Mishra;Shikha Pandey;P. Soundharrajan;Sarika Prabhakar Kombade;Pravin Kumar;Ram Prakash
{"title":"Characterization Study of a Helium Cold Atmospheric-Pressure Plasma Jet and Its Application in Plasma-Mediated Root Canal Irrigation","authors":"Abhijit Mishra;Sushma Jangra;Ritesh Mishra;Shikha Pandey;P. Soundharrajan;Sarika Prabhakar Kombade;Pravin Kumar;Ram Prakash","doi":"10.1109/TRPMS.2025.3628120","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3628120","url":null,"abstract":"This study focuses on the design and optimization of a cold atmospheric-pressure plasma (CAP) jet, particularly targeting plasma-mediated root canal irrigation for smear layer removal and Enterococcus faecalis disinfection. The dielectric barrier discharge (DBD)-based CAP jet, powered by a bipolar pulsed power supply, was systematically optimized by varying applied voltage, frequency, and helium gas flow rate to achieve optimal plasma parameters. The CAP jet, operating in a buoyant axisymmetric jet configuration, exhibited a transition from laminar to turbulent flow at helium flow rates exceeding 4 slpm corresponding Reynolds number of ~400. optical emission spectroscopy (OES) was utilized to identify species generated and determine plasma parameters, with the collisional–radiative (CR) model revealing a nonequilibrium nature characterized by electron density (<inline-formula> <tex-math>${n} {_{e} }~sim ~10{^{{1}}} {^{{3}}}$ </tex-math></inline-formula> cm<inline-formula> <tex-math>${}^{text {-3}}$ </tex-math></inline-formula>), electron temperature (<inline-formula> <tex-math>${T} {_{text {re}}}~sim ~0.35$ </tex-math></inline-formula> eV), and plasma gas temperature (<inline-formula> <tex-math>${T} {_{g} }~sim $ </tex-math></inline-formula> 305 K) under optimized conditions (4.5 kV, 20 kHz, 4 slpm). Fifty-Six mandibular premolars divided into four groups equally were irrigated with Normal saline solution (control) and CAP jet for 2, 5, and 10 min, respectively. Scanning electron microscope (SEM) imaging and disinfection analysis demonstrated significant improvements in smear layer removal and a ~5 log reduction in E. faecalis count, respectively. Smear layer removal was evaluated using the Kruskal–Wallis test, followed by Dunn’s post hoc analysis, whereas differences in bacterial load reduction across various CAP treatment times were analyzed using one-way ANOVA with Tukey’s honest significant difference (HSD) test for multiple comparisons. Safety considerations for medical applications, including gas temperature, leakage currents, and ozone emissions, were also evaluated according to DIN-specification 91315 (General requirements for plasma sources in medicine). These results underscore the promising application of plasma-mediated root canal irrigation, offering minimally invasive dental procedures, providing a foundation for further development and clinical translation in endodontics.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"995-1009"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PETAL-3D: Progressive Elimination of Noise Toward Accurate Ultra Low-Count PET Images Using 3-D U-Nets 花瓣- 3d:使用3-D U-Nets逐步消除对精确超低计数PET图像的噪声
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2025-11-28 DOI: 10.1109/TRPMS.2025.3638644
Ezzat Elmoujarkach;Fabian P. Schmidt;Eduardo Calderón;Wenhong Lan;Pia M. Linder;Lena S. Kiefer;Christian la Fougère;Magdalena Rafecas
{"title":"PETAL-3D: Progressive Elimination of Noise Toward Accurate Ultra Low-Count PET Images Using 3-D U-Nets","authors":"Ezzat Elmoujarkach;Fabian P. Schmidt;Eduardo Calderón;Wenhong Lan;Pia M. Linder;Lena S. Kiefer;Christian la Fougère;Magdalena Rafecas","doi":"10.1109/TRPMS.2025.3638644","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3638644","url":null,"abstract":"In Positron emission tomography (PET), reducing the amount of radiotracer administered reduces the effective dose, at the cost of increasing image statistical noise. For low-count PET, we proposed here Progressive Elimination of Noise Toward Accurate Ultra low-dose PET Images Using 3-D U-Nets (PETAL-3D), which operates by passing the low-count PET image (input) through multiple 3-D U-Net networks. So, the image noise is gradually removed. PETAL-3D was trained on data from two PET/CT scanners; a Siemens Biograph Vision Quadra and a United Imaging uEXPLORER. Patient scans with different noise levels were used to assess PETAL-3D performance, and compare it to Gaussian filtering and conventional 3-D U-Net denoising. PETAL-3D successfully restored images with a dose reduction factor (DRF) of 100 to a quality comparable to DRF20 images. After PETAL-3D denoising of DRF12 images, 91% of lesions were recovered, compared to 65% in the input. Physicians rated denoised DRF24 image quality as clinically acceptable, in contrast to the nondiagnostic quality of the DRF24 input images. A 90Y-PET scan of the AbdoMan phantom was denoised with PETAL-3D; despite the model was not trained on 90Y images, the coefficient of variation improved from 33% and 45% to 8% and 9%, in 30-min and 20-min equivalent scans, respectively.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"837-848"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11271363","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Member Get-a-Member (MGM) Program 米高梅会员计划
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2026-07-06 DOI: 10.1109/TRPMS.2026.3674614
{"title":"Member Get-a-Member (MGM) Program","authors":"","doi":"10.1109/TRPMS.2026.3674614","DOIUrl":"https://doi.org/10.1109/TRPMS.2026.3674614","url":null,"abstract":"","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"1010-1010"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11595780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epitaxial Quenching Resistor SiPM With Counting Rate Enhanced Technique Aiming at Photon-Counting CT Applications 面向光子计数CT应用的外延淬火电阻SiPM计数率增强技术
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2025-12-05 DOI: 10.1109/TRPMS.2025.3640670
Yongqiang Yan;Lin Zhang;Tianyu Yuan;Tianxi Sun;Kun Liang;Ru Yang;Dejun Han
{"title":"Epitaxial Quenching Resistor SiPM With Counting Rate Enhanced Technique Aiming at Photon-Counting CT Applications","authors":"Yongqiang Yan;Lin Zhang;Tianyu Yuan;Tianxi Sun;Kun Liang;Ru Yang;Dejun Han","doi":"10.1109/TRPMS.2025.3640670","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3640670","url":null,"abstract":"This study presents a high-performance photon counting detector (PCD) for photon-counting computed tomography (PCCT) applications, addressing the critical challenge of pulse pile-up at high X-ray photon fluxes. The PCD is composed of a fast Lu1.8Y0.2SiO5:Ce (LYSO) scintillator with an epitaxial quenching resistor type silicon photomultiplier (EQR SiPM), which features a small microcell pitch of <inline-formula> <tex-math>$10~mu $ </tex-math></inline-formula> m, a small active area of <inline-formula> <tex-math>$0.52times 0.52~{mathrm { mm}}^{2}$ </tex-math></inline-formula> and high fill factor of 49%. It exhibits a rapid recovery time of 1.85 ns and high photon detection efficiency (PDE) greater than 30%, thus is able to achieve a high photon counting rate while retaining adequate high energy resolution (ER). In order to further mitigate pile-up effects, a pole-zero cancellation (PZC) circuit was implemented to narrow pulse width from 46.1 ns to 19.5 ns (FWHM) along with a pile-up recovery algorithm (PRA) for pileup pulse discrimination. Experimental results demonstrate an ER of 37.7%(FWHM) at 59.5 keV (241Am, 24 kBq) and a maximum count rate (CR) of 102.7 Mcps/mm2 under 80 kV X-ray irradiation. This CR was twice as high as that obtained without using PRA methods. These preliminary results indicate the feasibility of EQR-silicon photomultiplier (SiPM)-based scintillation PCDs in clinical PCCT. The results demonstrate the PRA method’s efficacy in improving spectral performance under high flux conditions in a laboratory setting, though its clinical scalability remains challenging due to high computational demands.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"942-950"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zero-Shot Spatio–Temporal Interpolation Using Unsupervised Learning for CT Perfusion With Increased Sampling Interval 基于无监督学习的CT灌注零间隔时空插值
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2025-12-30 DOI: 10.1109/TRPMS.2025.3649121
Yu-Chun Lin;Chi-Kuang Liu;Hsuan-Ming Huang
{"title":"Zero-Shot Spatio–Temporal Interpolation Using Unsupervised Learning for CT Perfusion With Increased Sampling Interval","authors":"Yu-Chun Lin;Chi-Kuang Liu;Hsuan-Ming Huang","doi":"10.1109/TRPMS.2025.3649121","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3649121","url":null,"abstract":"Computed tomography perfusion (CTP) is recognized as a valuable tool for acute stroke diagnosis and management. Increasing the temporal sampling interval is a simple way to reduce radiation exposure, but it results in low temporal resolution that may fail to capture rapid perfusion change. To address this issue, we proposed a novel zero-shot spatio–temporal interpolation method that used unsupervised learning to restore CTP images with increased temporal sampling interval. Real brain CTP data with a 0.5-s sampling interval were quarterly subsampled to simulate a long sampling interval (i.e., 2-s) protocol. Then, the one-quarter subsampled CTP images were restored to the complete CTP images by using the proposed method. Finally, perfusion parameters were calculated from the complete and restored CTP images. Compared to the temporally subsampled and linearly interpolated (LI) CTP images, the unsupervised learning-restored CTP images produced perfusion maps more closely aligned with those derived from the completed CTP images, in terms of structural similarity index, mean absolute difference, and contrast-to-noise ratio. Moreover, the means relative differences obtained from the proposed method were lower than those obtained from the LI method in all cases. Our preliminary study shows that using unsupervised learning to restore CTP image frames from the CTP scan with an increased temporal sampling interval is feasible, indicating the possibility of reducing the radiation dose of CTP scans.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"920-929"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancing Dermatological Care: Potential of Gas Plasma Technology for Actinic Keratosis Treatment 推进皮肤科护理:气体等离子体技术在光化性角化病治疗中的潜力
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-07-01 Epub Date: 2025-12-05 DOI: 10.1109/TRPMS.2025.3639175
L. McKeever;L. Boeckmann;A. Bogaerts;S. Emmert;A. Privat-Maldonado;E. Robert;D. Singer;E. Smits;A. Stancampiano;A. Sobota;T. von Woedtke;K.-D. Weltmann;K. Wende;S. Bekeschus
{"title":"Advancing Dermatological Care: Potential of Gas Plasma Technology for Actinic Keratosis Treatment","authors":"L. McKeever;L. Boeckmann;A. Bogaerts;S. Emmert;A. Privat-Maldonado;E. Robert;D. Singer;E. Smits;A. Stancampiano;A. Sobota;T. von Woedtke;K.-D. Weltmann;K. Wende;S. Bekeschus","doi":"10.1109/TRPMS.2025.3639175","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3639175","url":null,"abstract":"actinic keratosis (AK) is a precancerous skin condition, often necessitating effective treatment to prevent progression to invasive, potentially lethal skin cancer. Traditional methods, such as cryotherapy and other topical therapies, pose various challenges, including discomfort and the potential for scarring. In recent years, medical gas plasma technology has emerged as a potential additional therapeutic option, leveraging the unique properties of such partially ionized gases to offer a noninvasive and targeted approach. This review critically evaluates clinical evidence from CE-certified plasma devices, including the kINPen MED and PlasmaDerm VU-2010, which demonstrate the efficacy and safety of plasma treatment in accelerating healing, lesion burden reduction, and skin rejuvenation. Building on these clinical insights, the review also outlines the underlying mechanisms of plasma-induced oxidative stress, discusses advancements in device design that enhance treatment precision and patient comfort, and highlights existing challenges such as standardization and reproducibility. Together, these findings position medical gas plasma as a compelling addition to the dermatological treatment landscape and underscore the need for continued translational and clinical research to establish its place in standard AK therapy.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 6","pages":"981-994"},"PeriodicalIF":3.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11278788","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148442785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and Initial Optimization of Reconstruction Performance for Detector Crosstalk of Ultrahigh Performance Brain PET Imager. 超高性能脑PET成像仪探测器串扰重构性能表征及初步优化。
IF 3.8
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-06-01 DOI: 10.1109/trpms.2026.3698769
Jiazhen Zhang, Kathryn Fontaine, Tiantian Li, Paul Gravel, Takuya Toyonaga, Yifan Hu, Jean-Dominique Gallezot, Tianyi Zeng, Tommaso Volpi, Yihuan Lu, Thibault Marin, Jinyi Qi, Richard E Carson
{"title":"Characterization and Initial Optimization of Reconstruction Performance for Detector Crosstalk of Ultrahigh Performance Brain PET Imager.","authors":"Jiazhen Zhang, Kathryn Fontaine, Tiantian Li, Paul Gravel, Takuya Toyonaga, Yifan Hu, Jean-Dominique Gallezot, Tianyi Zeng, Tommaso Volpi, Yihuan Lu, Thibault Marin, Jinyi Qi, Richard E Carson","doi":"10.1109/trpms.2026.3698769","DOIUrl":"10.1109/trpms.2026.3698769","url":null,"abstract":"<p><p>The NeuroEXPLORER (NX) is a next-generation, ultrahigh-performance brain positron emission tomography/computed tomography (PET/CT) system designed for both high spatial resolution and sensitivity. To meet high-sensitivity (HS) requirements, the system uses 2-cm-long scintillation crystals, while the novel U-shaped depth-of-interaction (DOI) encoding and small crystal elements enable high resolution. However, using long, small crystals increases signal crosstalk between crystals arising from Compton scattering, photoelectron escape, and incomplete optical isolation, which can degrade spatial resolution. Although the NX electronics detect crosstalk between microblocks and support real-time recovery using measured energy, accurate identification of the first interaction point is not always possible. Incorporating crosstalk events increases coincidence sensitivity by approximately 50% but compromises spatial resolution. Given such a large fraction of detector crosstalk, evaluating its impact on reconstruction performance in the NX is imperative. In this work, we evaluated image resolution in three reconstruction modes: (HS; all events), higher resolution (HR; noncrosstalk events), and lower resolution (LR; crosstalk events), using real phantoms and human studies with multiple tracers. Guided by the resolution characterization of the HYDRA-OLG brain phantom, we introduced a two-Gaussian mixture point spread function (2G-PSF) for HS reconstruction to improve contrast while suppressing noise. At matched iterations, HR yielded the highest image contrast, HS showed slightly reduced contrast, and LR exhibited the largest partial volume effect, as expected. Modeling crosstalk with the 2G-PSF for HS increased contrast toward HR levels without sacrificing sensitivity. Overall, these results provide a practical strategy for including crosstalk events in high-resolution PET systems while mitigating their impact on spatial resolution.</p>","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geant4 Simulation of Cherenkov Photons in Perovskite CsPbBr3 Gamma-Ray Detectors 钙钛矿CsPbBr3伽玛射线探测器Cherenkov光子的Geant4模拟
IF 3.5
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-04-01 Epub Date: 2025-10-27 DOI: 10.1109/TRPMS.2025.3625546
Lei Pan;Seungeun Lee;Phan Quoc Vuong;Mustafa Unal;Indra Raj Pandey;Duck Young Chung;Mercouri G. Kanatzidis;Brian J. Quiter
{"title":"Geant4 Simulation of Cherenkov Photons in Perovskite CsPbBr3 Gamma-Ray Detectors","authors":"Lei Pan;Seungeun Lee;Phan Quoc Vuong;Mustafa Unal;Indra Raj Pandey;Duck Young Chung;Mercouri G. Kanatzidis;Brian J. Quiter","doi":"10.1109/TRPMS.2025.3625546","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3625546","url":null,"abstract":"Perovskite materials have recently attracted significant attention for hard X-ray and gamma-ray detection. Cherenkov light generated by fast electrons due to gamma-ray interaction with the material can be used to provide fast timing information. Here, we report Geant4 simulation results of Cherenkov photon generation, transport, and detection within perovskite CsPbBr3. The Cherenkov photon yield, energy spectrum and temporal distribution are investigated under different gamma-ray energy deposition within CsPbBr3. <inline-formula> <tex-math>$rm CsPbBr_{3}$ </tex-math></inline-formula> has a similar Cherenkov photon yield as of TlBr that has demonstrated fast-timing capability based on Cherenkov light. The effect of crystal volume, surface finish and silicon photomultiplier (SiPM) photon detection efficiency on the Cherenkov detection is also discussed. This work provides insights into Cherenkov processes of CsPbBr3.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 4","pages":"566-573"},"PeriodicalIF":3.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147588240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of a Dual-Panel In-Beam PET Based on Digital Detectors for Proton Therapy Monitoring With Different Monitoring Strategies: A Simulation Study 基于数字探测器的双面板束内PET不同监测策略质子治疗监测的仿真研究
IF 3.5
IEEE Transactions on Radiation and Plasma Medical Sciences Pub Date : 2026-04-01 Epub Date: 2025-06-30 DOI: 10.1109/TRPMS.2025.3584122
Dengyun Mu;Ao Qiu;Qi Liu;Qiuhui Ma;Lin Wan;Peng Xiao;Pengyuan Qi;Gang Liu;Sheng Zhang;Kunyu Yang;Jianchun Deng;Zixiao Liu;Qiyun Liu;Yang Liu;Zhiyong Yang;Qingguo Xie
{"title":"Investigation of a Dual-Panel In-Beam PET Based on Digital Detectors for Proton Therapy Monitoring With Different Monitoring Strategies: A Simulation Study","authors":"Dengyun Mu;Ao Qiu;Qi Liu;Qiuhui Ma;Lin Wan;Peng Xiao;Pengyuan Qi;Gang Liu;Sheng Zhang;Kunyu Yang;Jianchun Deng;Zixiao Liu;Qiyun Liu;Yang Liu;Zhiyong Yang;Qingguo Xie","doi":"10.1109/TRPMS.2025.3584122","DOIUrl":"https://doi.org/10.1109/TRPMS.2025.3584122","url":null,"abstract":"In-beam positron emission tomography (PET) has shown great potential as a technology for proton therapy monitoring. Our group has developed a compact all-digital PET detector with high coincidence time resolution and energy resolution. Based on this detector, this study investigated the feasibility of a dual-panel in-beam PET (DiB-PET) system for proton therapy monitoring through Monte Carlo simulations. We designed a single-field treatment plan for an intracranial tumor and investigated three monitoring strategies: 1) monitoring the range of a single spot; 2) monitoring the range of a single mid-energy layer; and 3) monitoring the range of a single-field plan. We introduced range deviations by varying the soft tissue density and evaluated the range verification accuracy by quantifying the linear relationship between activity range shift and dose range shift. With 120 s PET acquisition, DiB-PET achieved an average range verification accuracy of approximately 1.0 mm. This accuracy was consistent across all three monitoring strategies: on a spot-by-spot basis for both a single spot and a single mid-energy layer, as well as on a voxel-by-voxel basis for a single-field plan. These findings highlight DiB-PET’s high sensitivity and versatility, demonstrating its feasibility for proton therapy monitoring.","PeriodicalId":46807,"journal":{"name":"IEEE Transactions on Radiation and Plasma Medical Sciences","volume":"10 4","pages":"582-592"},"PeriodicalIF":3.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147588279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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