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Applied Biochemistry and Biotechnology最新文献

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The Transcription Factor SOX6 Regulates Autophagy Levels Through LAMP5 to Inhibit the Development of Pituitary Adenomas. 转录因子SOX6通过LAMP5调控自噬水平抑制垂体腺瘤的发展。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-21 DOI: 10.1007/s12010-026-05703-z
Zhuohui Liu, Xiufu Liao, Hexiang Zhao, Biao Ruan, Fengfeng Jia, Ruiqing Long
{"title":"The Transcription Factor SOX6 Regulates Autophagy Levels Through LAMP5 to Inhibit the Development of Pituitary Adenomas.","authors":"Zhuohui Liu, Xiufu Liao, Hexiang Zhao, Biao Ruan, Fengfeng Jia, Ruiqing Long","doi":"10.1007/s12010-026-05703-z","DOIUrl":"https://doi.org/10.1007/s12010-026-05703-z","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comprehensive Analysis of scRNA-Seq and RNA-Seq Revealed the Role of Programmed Cell Death-Related Genes in the Prognosis of Glioblastoma Patients. scRNA-Seq和RNA-Seq综合分析揭示细胞程序性死亡相关基因在胶质母细胞瘤患者预后中的作用
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-20 DOI: 10.1007/s12010-026-05687-w
Yifan Tang, Puyuan Zhao, Yang Gao, Hantao Yang, Jinglong Huang, Liangliang Yang
{"title":"Comprehensive Analysis of scRNA-Seq and RNA-Seq Revealed the Role of Programmed Cell Death-Related Genes in the Prognosis of Glioblastoma Patients.","authors":"Yifan Tang, Puyuan Zhao, Yang Gao, Hantao Yang, Jinglong Huang, Liangliang Yang","doi":"10.1007/s12010-026-05687-w","DOIUrl":"https://doi.org/10.1007/s12010-026-05687-w","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Study on the Environmentally Relevant Concentration of Cytotoxic Drug Cyclophosphamide on the Biochemical Responses of the Freshwater Mussel Lamellidens marginalis. 环境相关浓度细胞毒性药物环磷酰胺对淡水贻贝生化反应的慢性研究。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-20 DOI: 10.1007/s12010-026-05698-7
Ashokkumar Sibiya, Chandrabose Selvaraj, Deepali Desai, Baskaralingam Vaseeharan
{"title":"Chronic Study on the Environmentally Relevant Concentration of Cytotoxic Drug Cyclophosphamide on the Biochemical Responses of the Freshwater Mussel Lamellidens marginalis.","authors":"Ashokkumar Sibiya, Chandrabose Selvaraj, Deepali Desai, Baskaralingam Vaseeharan","doi":"10.1007/s12010-026-05698-7","DOIUrl":"https://doi.org/10.1007/s12010-026-05698-7","url":null,"abstract":"<p><p>Increased prevalence of cancer leads to a gradual escalation in the consumption of anticancer drugs. Cyclophosphamide (CP), the most preferred anti-cancerous drug has been reported to be present in aquatic ecosystems and cause cellular damage in aquatic organisms. The current work determined the chronic (28 days) toxicity of ecologically pertinent quantity of CP (control-0), 0.1, 0.5, 1.0 and 5.0 µg/L of the freshwater mussel Lamellidens marginalis. Alterations in the energy reserves, oxidative stress and cellular damages such as lipid peroxidation, protein carbonyl activity, and antioxidant defences superoxide dismutase, catalase, glutathione peroxidase, redox balance reduced glutathione, neurotoxicity and histological damages were observed. The obtained results reveal that animals maintain their metabolic capacity with increased energy reserves in the uppermost exposure group. Increased quantity of CP accumulation was detected in exposed water samples than in gill tissues. A noteworthy decrease (p ≤ 0.005) in antioxidant activity was obtained in 0.5 and 5.0 µg/L of CP concentration. Overall, the present findings reveal that increased concentration of CP alters antioxidant defence mechanisms in Lamellidens marginalis.</p>","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nature's Power at Nanoscale: Isolation and Characterization of Exosome-like Nanovesicles from Murraya koenigii. 自然在纳米尺度上的力量：从Murraya koenigii中分离和表征外泌体样纳米囊泡。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-18 DOI: 10.1007/s12010-026-05699-6
Anna Maria Kollannur, Gayathri M
{"title":"Nature's Power at Nanoscale: Isolation and Characterization of Exosome-like Nanovesicles from Murraya koenigii.","authors":"Anna Maria Kollannur, Gayathri M","doi":"10.1007/s12010-026-05699-6","DOIUrl":"https://doi.org/10.1007/s12010-026-05699-6","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147715502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrated Spatial Metabolomics and Transcriptomics Decipher the Effect of Chronic Stress on the Progression of Liver Cancer. 综合空间代谢组学和转录组学揭示慢性应激对肝癌进展的影响。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-17 DOI: 10.1007/s12010-026-05690-1
Meiyuan Wang, Shuhua Pei, Rongjin Wang, Shu Liu, Zong Hou, Zhongying Liu
{"title":"Integrated Spatial Metabolomics and Transcriptomics Decipher the Effect of Chronic Stress on the Progression of Liver Cancer.","authors":"Meiyuan Wang, Shuhua Pei, Rongjin Wang, Shu Liu, Zong Hou, Zhongying Liu","doi":"10.1007/s12010-026-05690-1","DOIUrl":"https://doi.org/10.1007/s12010-026-05690-1","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147697150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway. 下调GBP5可通过NF-κB途径减弱腹主动脉瘤的形成。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-17 DOI: 10.1007/s12010-026-05689-8
Yongsheng Wang, Jiangang Wang, Zhonglu Chang
{"title":"Knockdown of GBP5 Attenuates Abdominal Aortic Aneurysm Formation via the NF-κB Pathway.","authors":"Yongsheng Wang, Jiangang Wang, Zhonglu Chang","doi":"10.1007/s12010-026-05689-8","DOIUrl":"https://doi.org/10.1007/s12010-026-05689-8","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147697211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ATP6V1B2 Regulating Autophagy Flux To Affect Abnormal Auditory Development. ATP6V1B2调节自噬通量影响听觉异常发育。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-17 DOI: 10.1007/s12010-025-05579-5
ZiFang Feng, Jie Li, YunZhong Yang, MingLu Chen, XueMei Wu, ChengYing Zhou
{"title":"ATP6V1B2 Regulating Autophagy Flux To Affect Abnormal Auditory Development.","authors":"ZiFang Feng, Jie Li, YunZhong Yang, MingLu Chen, XueMei Wu, ChengYing Zhou","doi":"10.1007/s12010-025-05579-5","DOIUrl":"https://doi.org/10.1007/s12010-025-05579-5","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147715435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Loop-Mediated Isothermal Amplification Assay for the Detection of aaic Positive Enteroaggregative Escherichia coli (EAEC). 环介导等温扩增法检测aaic阳性肠聚集性大肠杆菌（EAEC）的建立。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-17 DOI: 10.1007/s12010-026-05700-2
Alazar Amare Amdiyee, Tesfaye Sisay Tessema
{"title":"Development of Loop-Mediated Isothermal Amplification Assay for the Detection of aaic Positive Enteroaggregative Escherichia coli (EAEC).","authors":"Alazar Amare Amdiyee, Tesfaye Sisay Tessema","doi":"10.1007/s12010-026-05700-2","DOIUrl":"https://doi.org/10.1007/s12010-026-05700-2","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147697103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyaluronic Acid Increase Anti-Inflammatory and Regenerative Effects of Adipose-Derived Mesenchymal Stem Cells in an Interstitial Cystitis Rat Model. 透明质酸增加间质性膀胱炎大鼠模型中脂肪来源的间充质干细胞的抗炎和再生作用。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-16 DOI: 10.1007/s12010-026-05677-y
Amal F Dawood, Rashad Qasem Ali Othman, Baker M Albow, Elryah I Ali, Abdelnaser A Badawy, Mahmoud Abdel-Maboud, Nada Ashraf, Intisar I Ali, Raghda W Magar, Mamdouh Eldesoqui
{"title":"Hyaluronic Acid Increase Anti-Inflammatory and Regenerative Effects of Adipose-Derived Mesenchymal Stem Cells in an Interstitial Cystitis Rat Model.","authors":"Amal F Dawood, Rashad Qasem Ali Othman, Baker M Albow, Elryah I Ali, Abdelnaser A Badawy, Mahmoud Abdel-Maboud, Nada Ashraf, Intisar I Ali, Raghda W Magar, Mamdouh Eldesoqui","doi":"10.1007/s12010-026-05677-y","DOIUrl":"https://doi.org/10.1007/s12010-026-05677-y","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147697076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UHPLC-MS/MS-based Untargeted Metabolomics Reveals Changes in Metabolites of Ligusticum chuanxiong During Irradiation. UHPLC-MS/MS-based非靶向代谢组学揭示川芎代谢产物在辐照过程中的变化
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-16 DOI: 10.1007/s12010-026-05629-6
Xin Jia, Peng Gao, Yan Wang, Yi Fu, Pan Xu, Min Huang
{"title":"UHPLC-MS/MS-based Untargeted Metabolomics Reveals Changes in Metabolites of Ligusticum chuanxiong During Irradiation.","authors":"Xin Jia, Peng Gao, Yan Wang, Yi Fu, Pan Xu, Min Huang","doi":"10.1007/s12010-026-05629-6","DOIUrl":"https://doi.org/10.1007/s12010-026-05629-6","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147697235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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