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Immunomodulatory Effects of Huaier Extract on Th1/Th2 Polarization Through IL-33/ST2 Axis Regulation in Allergic Rhinitis Pathogenesis. 淮儿提取物通过IL-33/ST2轴调控对变应性鼻炎发病中Th1/Th2极化的免疫调节作用
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-27 DOI: 10.1007/s12010-026-05706-w
Rong-Gang Yang, Yun-Song Li, Yu Xiong, You-Qing Liang, Qi Yao
{"title":"Immunomodulatory Effects of Huaier Extract on Th1/Th2 Polarization Through IL-33/ST2 Axis Regulation in Allergic Rhinitis Pathogenesis.","authors":"Rong-Gang Yang, Yun-Song Li, Yu Xiong, You-Qing Liang, Qi Yao","doi":"10.1007/s12010-026-05706-w","DOIUrl":"https://doi.org/10.1007/s12010-026-05706-w","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritive Constituents' Variation in Main Parts of Dendrocalamus Brandisii and the Silage Fermentation for Bamboo-Based Ruminant Feed. 竹菖蒲主要部位营养成分变化及竹基反刍动物饲料青贮发酵研究
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-27 DOI: 10.1007/s12010-026-05708-8
Biying Guo, Xia Hua, Yanan Chen, Xin Zhou, Li Zhang, Qiang Yong, Yong Xu
{"title":"Nutritive Constituents' Variation in Main Parts of Dendrocalamus Brandisii and the Silage Fermentation for Bamboo-Based Ruminant Feed.","authors":"Biying Guo, Xia Hua, Yanan Chen, Xin Zhou, Li Zhang, Qiang Yong, Yong Xu","doi":"10.1007/s12010-026-05708-8","DOIUrl":"https://doi.org/10.1007/s12010-026-05708-8","url":null,"abstract":"<p><p>The booming food and feed industries strongly promote the exploration of new resources, while Dendrocalamus brandisii presents a promising potential for application for the vigorous growth and abundant harvest in Southeast Asia. To further utilize and increase the value of Dendrocalamus brandisii, firstly, main different parts were comparatively analyzed, while digestive and nutritional indexes were evaluated. As a result, bamboo shoots and leaves contain 26.3% and 20.7% of crude protein, respectively. The relative feed values of bamboo leaves, leaf stems, shoots shells and shoots all exceed 80%. As analyzed, bamboo leaves were promising for producing feed. Afterwards, the silage fermentation of bamboo leaves was carried out, during which the effects of different additives and the changes in nutritive index of bamboo leaves were investigated. By fermenting with composite bacterial inoculum of Lacticaseibacillus paracasei, Saccharomyces cerevisiae and Bacillus subtilis, neutral-detergent fiber and acid-detergent fiber in leaves were decreased significantly by 22.68%~30.36% to produce 55.03 ~ 89.47 g/kg organic acids with over 60 g/kg domination of lactic acid, while crude protein was maintained well. The exogenous cellulase assisted Lacticaseibacillus paracesei fermentation exhibited the fastest decrease in pH (3.68) and the highest lactic acid content (78.68 g/kg). This study provides foundational data on Dendrocalamus brandisii's nutritive composition and demonstrates the feasibility of bamboo leaf-based feed production with potential for scaled implementation in bunkers. Moreover, this approach can facilitate the utilization of sustainable bamboo resource by converting it into high-value feed product and reduce pressure on conventional agricultural system.</p>","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enzymatic Degradation of Polycaprolactone by Cutinase-Producing Bacteria Isolated from Plastic-Contaminated Environments. 塑料污染环境中角质酶产菌降解聚己内酯的研究
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-25 DOI: 10.1007/s12010-026-05709-7
Sermin Yıldırım, Hamdi Öğüt
{"title":"Enzymatic Degradation of Polycaprolactone by Cutinase-Producing Bacteria Isolated from Plastic-Contaminated Environments.","authors":"Sermin Yıldırım, Hamdi Öğüt","doi":"10.1007/s12010-026-05709-7","DOIUrl":"https://doi.org/10.1007/s12010-026-05709-7","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteoclast Precursor Membrane-Coated Nanoparticles Loaded With Abaloparatide Enable Dual Modulation of Osteoclast and Osteoblast Differentiation. 载abalopar肽的破骨细胞前体膜包被纳米颗粒能够双重调节破骨细胞和成骨细胞的分化。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-25 DOI: 10.1007/s12010-026-05701-1
Mingfu Fu, Qiaoling Zhu, Anqing Chen, Xueyan Liu, Yinghui Sui
{"title":"Osteoclast Precursor Membrane-Coated Nanoparticles Loaded With Abaloparatide Enable Dual Modulation of Osteoclast and Osteoblast Differentiation.","authors":"Mingfu Fu, Qiaoling Zhu, Anqing Chen, Xueyan Liu, Yinghui Sui","doi":"10.1007/s12010-026-05701-1","DOIUrl":"https://doi.org/10.1007/s12010-026-05701-1","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147758902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing the Antimicrobial Efficacy of CTS Through Complexation and Nanoengineering with Zn: Emerging Trends (2018–2025) 通过锌络合和纳米工程增强CTS的抗菌效果：新趋势（2018-2025）。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-25 DOI: 10.1007/s12010-026-05711-z
Mohammed Sanad Alhussaini, AbdulRahman Abdulla Ibrahim Alyahya
{"title":"Enhancing the Antimicrobial Efficacy of CTS Through Complexation and Nanoengineering with Zn: Emerging Trends (2018–2025)","authors":"Mohammed Sanad Alhussaini,&nbsp;AbdulRahman Abdulla Ibrahim Alyahya","doi":"10.1007/s12010-026-05711-z","DOIUrl":"10.1007/s12010-026-05711-z","url":null,"abstract":"<div>\u0000 \u0000 <p>Chitosan (CTS), a naturally derived polysaccharide from chitin, exhibits intrinsic but relatively moderate antimicrobial activity, typically requiring high concentrations to achieve significant inhibition. To overcome this limitation, recent research has focused on Zn(II) complexation and nanoengineering approaches, which have demonstrated substantial improvements in antimicrobial efficacy. Reported minimum inhibitory concentration (MIC) values for CTS-Zn systems are frequently reduced compared to CTS, with enhanced activity observed against both Gram-positive and Gram-negative pathogens. This enhancement is attributed to synergistic mechanisms, including improved membrane permeability, sustained Zn<sup>2+</sup> ion release, and increased surface area in nanostructured forms. This review presents a comparative analysis of CTS-Zn(II) complexes and CTS-based Zn nanomaterials, examining the impact of coordination modes, particle size, and surface charge on antimicrobial activity. Unlike previous descriptive reviews, this work systematically correlates physicochemical modifications with antimicrobial performance, highlighting that variations in synthesis strategies and material design influence the antimicrobial activity. Special emphasis is placed on Zn(II) complexation and nanoengineering approaches to enhance the antimicrobial efficacy of CTS.</p>\u0000 </div>","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":"198 5","pages":"3364 - 3389"},"PeriodicalIF":3.3,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Vivo and In Silico Evaluation of the Anti-Arthritic Potential of an Isoxazole Derivative. 异恶唑衍生物抗关节炎潜能的体内和计算机评价。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-24 DOI: 10.1007/s12010-026-05692-z
Farida Munir, Aisha Mobashar, Muhammad Bilal, Ammara Saleem, Arham Shabbir, Hossam Kamli, Narmeen Mehmood, Amir Ali, Zeeshan Akbar, Humaira Nadeem, Iqra Zulfiqar, Sana Saleem, Esmael M Alyami, Mona Alsolami, Amir Bouallegue, Mohammed Bourhia, Gehan M Elossaily, Khalid S Almaary
{"title":"In Vivo and In Silico Evaluation of the Anti-Arthritic Potential of an Isoxazole Derivative.","authors":"Farida Munir, Aisha Mobashar, Muhammad Bilal, Ammara Saleem, Arham Shabbir, Hossam Kamli, Narmeen Mehmood, Amir Ali, Zeeshan Akbar, Humaira Nadeem, Iqra Zulfiqar, Sana Saleem, Esmael M Alyami, Mona Alsolami, Amir Bouallegue, Mohammed Bourhia, Gehan M Elossaily, Khalid S Almaary","doi":"10.1007/s12010-026-05692-z","DOIUrl":"https://doi.org/10.1007/s12010-026-05692-z","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunotherapy Treatment of Colorectal Cancer and Lung Metastasis with Genetically Modified Outer Membrane Vesicles Delivering Poly-Neoepitopes in a Mouse Model. 基因修饰外膜囊泡传递多新表位在小鼠模型中的免疫治疗结肠癌和肺转移
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-24 DOI: 10.1007/s12010-026-05646-5
Elham Sharif, Leila Nematollahi, Elham Mohit
{"title":"Immunotherapy Treatment of Colorectal Cancer and Lung Metastasis with Genetically Modified Outer Membrane Vesicles Delivering Poly-Neoepitopes in a Mouse Model.","authors":"Elham Sharif, Leila Nematollahi, Elham Mohit","doi":"10.1007/s12010-026-05646-5","DOIUrl":"https://doi.org/10.1007/s12010-026-05646-5","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of Chitosanase-3-like Protein 1 in Outflow Tract Veins of Patients with Autologous Arteriovenous Fistula Failure and Potential Involvement with Phenotypic Transformation of Medial Smooth Muscle Cells. 壳聚糖酶-3样蛋白1在自体动静脉瘘失败患者流出道静脉中的表达及其与内侧平滑肌细胞表型转化的潜在关系
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-23 DOI: 10.1007/s12010-026-05675-0
XueBo Chen, Ji Xu, FengLiang Yao, SiShi Yan
{"title":"Expression of Chitosanase-3-like Protein 1 in Outflow Tract Veins of Patients with Autologous Arteriovenous Fistula Failure and Potential Involvement with Phenotypic Transformation of Medial Smooth Muscle Cells.","authors":"XueBo Chen, Ji Xu, FengLiang Yao, SiShi Yan","doi":"10.1007/s12010-026-05675-0","DOIUrl":"https://doi.org/10.1007/s12010-026-05675-0","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CEBPD-MMP8 Axis Contributes to Cardiomyocyte Injury in Septic Shock. CEBPD-MMP8轴参与感染性休克的心肌细胞损伤。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-22 DOI: 10.1007/s12010-026-05707-9
Yang Yu, Decui Pei, Jia Liu, Keming Chen, Wenjing Zhang, Heying Zhong
{"title":"CEBPD-MMP8 Axis Contributes to Cardiomyocyte Injury in Septic Shock.","authors":"Yang Yu, Decui Pei, Jia Liu, Keming Chen, Wenjing Zhang, Heying Zhong","doi":"10.1007/s12010-026-05707-9","DOIUrl":"https://doi.org/10.1007/s12010-026-05707-9","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Desiccation-Induced Oxidative Stress Causes Metabolic Flux in the Terrestrial Green Alga Trentepohlia sp., Suggesting Extensive Metabolic Reprogramming for Stress Adaptation. 干旱诱导的氧化应激引起陆生绿藻的代谢通量，提示广泛的代谢重编程以适应应激。
IF 3.3 4区 生物学
Applied Biochemistry and Biotechnology Pub Date : 2026-04-21 DOI: 10.1007/s12010-026-05693-y
Parul Sharma, Shuvasish Choudhury, Jayashree Rout
{"title":"Desiccation-Induced Oxidative Stress Causes Metabolic Flux in the Terrestrial Green Alga Trentepohlia sp., Suggesting Extensive Metabolic Reprogramming for Stress Adaptation.","authors":"Parul Sharma, Shuvasish Choudhury, Jayashree Rout","doi":"10.1007/s12010-026-05693-y","DOIUrl":"https://doi.org/10.1007/s12010-026-05693-y","url":null,"abstract":"","PeriodicalId":465,"journal":{"name":"Applied Biochemistry and Biotechnology","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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