{"title":"Reflections on suzetrigine and the evolving landscape of non-opioid analgesia.","authors":"Antonio Alcántara Montero","doi":"10.1177/20494637261430909","DOIUrl":"10.1177/20494637261430909","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261430909"},"PeriodicalIF":1.5,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12953157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lawrence Roux, Sylvia M Gustin, Toby Ro Newton-John
{"title":"A qualitative analysis of healthcare professionals' perspectives on goal adjustment in chronic pain.","authors":"Lawrence Roux, Sylvia M Gustin, Toby Ro Newton-John","doi":"10.1177/20494637261418200","DOIUrl":"10.1177/20494637261418200","url":null,"abstract":"<p><strong>Introduction: </strong>This qualitative study investigated clinician perspectives on the relevance and significance of goal adjustment in the treatment of chronic pain. Although a common experience for many people living with chronic pain, goal adjustment remains underexplored in the therapeutic literature. Exploring clinicians' experiences can optimize treatment strategies for individuals whose chronic pain imposes functional limitations, and where significant adjustments to important life aspirations are required.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 14 experienced pain clinicians, including medical specialists, physiotherapists, and clinical psychologists. The interviews explored three areas: the relevance of goal adjustment in clinical practice, factors that enhance and hinder flexible goal adjustment, and treatment strategies for redirecting patient efforts towards alternative more viable aspirations. An inductive thematic analysis was performed to identify key themes from the data.</p><p><strong>Results: </strong>Clinicians unanimously endorsed the view that goal adjustment issues commonly occur when treating chronic pain. The thematic analysis highlighted the importance of flexible goal adjustment and the distress caused by letting go of goal ambitions. The consequences of problematic or inflexible goal adjustment are explored, along with barriers and facilitators of goal adjustment in chronic pain. Themes such as rigid self-identity, cognitive rigidity, limited understanding of chronic pain, and emotional distress were identified as barriers. The role of family, health professionals, and other social influences is also discussed. Therapeutic approaches emphasize realistic and meaningful goals, timing, rapport, trust, values-based goals, and validating distress.</p><p><strong>Discussion: </strong>The findings suggest that goal adjustment is a well-recognized component of chronic pain treatment. Experienced pain clinicians identified that the successful resolution of the challenges of goal adjustment and the implementation of effective strategies to adopt realistic expectations is critical for positive patient outcomes. This study underscores the importance of integrating goal adjustment frameworks into chronic pain management to enhance therapeutic efficacy.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261418200"},"PeriodicalIF":2.8,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146182991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason Luo, Mark Woodward, Manuela L Ferreira, Katie Harris
{"title":"Sex differences in the experience of pain in the UK Biobank cohort study.","authors":"Jason Luo, Mark Woodward, Manuela L Ferreira, Katie Harris","doi":"10.1177/20494637261418196","DOIUrl":"10.1177/20494637261418196","url":null,"abstract":"<p><strong>Objective: </strong>Chronic pain has been shown to be more prevalent among women than men. However, each person's experience of pain is shaped by a complex interplay of biological, psychological and social factors. The aim of this study was to summarise a comprehensive 'experience of pain' questionnaire in the UK Biobank and identify differences in the experience of chronic pain between females and males.</p><p><strong>Methods: </strong>This was an exploratory analysis of an online self-assessment questionnaire consisting of 128 questions related to UK Biobank participant's experience of pain that was administered in 2019. Data were summarised by sex, and chi-squared and <i>t</i>-tests were used to determine whether there were statistically significant differences between females and males.</p><p><strong>Results: </strong>About one-third of UK Biobank participants (167,183, 57% female) responded to the questionnaire. More females than males reported suffering from chronic pain (60.0% vs 51.5%). There was female predominance in 11 out of 14 medical conditions, particularly in osteoarthritis (35.6% females vs 24.5% males), migraine (25.0% vs 12.3%) and fibromyalgia (2.7% vs 0.7%). Female participants tended to report pain of greater severity and longer duration that more profoundly impairs their everyday functioning when compared to their male counterparts.</p><p><strong>Conclusion: </strong>A significant strength of our study is the large sample size, and the high detail of information captured about pain phenotypes, in which we found sex differences in chronic pain persist. We recommend future pain surveys collect sex-based pain conditions to enable better recognition of why sex differences in pain persist.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261418196"},"PeriodicalIF":2.8,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12827042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Suzetrigine and the evolving landscape of non-opioid analgesia.","authors":"Zoreiz Zahid Cheema, Ebaad Hassan, Nadia Siddiq","doi":"10.1177/20494637261418201","DOIUrl":"10.1177/20494637261418201","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261418201"},"PeriodicalIF":2.8,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12812055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samar Rafik Amin, Mona Ahmed Elhadad, Eslam Abdelshafy Tabl, Zeinab Mohammed Abdelwahab
{"title":"Ultrasound-guided pericapsular nerve group block versus caudal epidural block for postoperative pain management in pediatric hip surgery: A randomized clinical trial.","authors":"Samar Rafik Amin, Mona Ahmed Elhadad, Eslam Abdelshafy Tabl, Zeinab Mohammed Abdelwahab","doi":"10.1177/20494637261418203","DOIUrl":"10.1177/20494637261418203","url":null,"abstract":"<p><strong>Introduction: </strong>Optimal pain control after pediatric hip surgery enhances recovery, minimizes opioid needs, and improves comfort. The pericapsular nerve group (PENG) block, a unique regional intervention, has advantages over the standard caudal epidural block (CEB). This study compares the analgesic efficacy of ultrasound-guided PENG and CEB blocks in children having hip surgery.</p><p><strong>Methods: </strong>This study included 80 pediatric patients, aged 1 to 7 years, who received general anesthesia for hip surgery. Patients were randomly allocated to receive either a PENG block (Group P) using 0.5 mL/kg of 0.25% bupivacaine, or a CEB (Group C) using equivalent bupivacaine volume. The primary outcome was postoperative pain assessed by the FLACC scale at predefined timepoints. Secondary measured outcomes were the time until the first rescue analgesic, total morphine usage, occurrence of adverse effects, and parental satisfaction.</p><p><strong>Results: </strong>Pain scores were generally comparable, but Group C showed significantly lower FLACC scores at 30 min (<i>p</i> = .047), while Group P had lower scores at 6 h (<i>p</i> = .024). Group P demonstrated a significantly longer time to first rescue analgesic (10.68 ± 7.03 vs 7.85 ± 4.77 h, <i>p</i> = .039) and lower morphine consumption (<i>p</i> = .047). Block performance time was greater in Group P (<i>p</i> < .001), but higher parental satisfaction was noted (p = .03). The safety profile was equivalent between groups, with no significant disparity in adverse effect frequency.</p><p><strong>Conclusion: </strong>For pediatric hip surgery, ultrasound-guided PENG block provides long-lasting postoperative analgesia compared to CEB, while reducing opioid needs and enhancing parent satisfaction.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261418203"},"PeriodicalIF":2.8,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cassandra Macgregor, Christopher Seenan, Sivaramkumar Shanmugam, David N Blane
{"title":"Who is providing pain care? Mapping chronic pain services across Scotland using freedom of information requests.","authors":"Cassandra Macgregor, Christopher Seenan, Sivaramkumar Shanmugam, David N Blane","doi":"10.1177/20494637251413581","DOIUrl":"10.1177/20494637251413581","url":null,"abstract":"<p><strong>Background: </strong>The Scottish Service Model for Chronic Pain advocates multidisciplinary provision of care, stratified across sectors. However, there is lack of transparency over staffing capacities and provisions.</p><p><strong>Method: </strong>We submitted Freedom of Information requests to the 14 regional Scottish Health Boards in September 2024. We conducted descriptive quantitative and qualitative analysis of responses.</p><p><strong>Findings: </strong>We received 13 responses from 14 Health Boards with varying levels of detail. We found that staff groups most commonly reported to provide dedicated care for chronic pain are: medicine, physiotherapy, psychology and nursing, with lower levels of occupational therapy and pharmacy provision. Six Boards reported at least 1.0 whole-time equivalent medical, physiotherapy and psychology staffing capacity per 500,000 population, with sparse provisions by some populous Boards, showing considerable variation. A variety of pain groups were reported. Boards with higher levels of multidisciplinary staffing and group provision tended to report a dedicated management resource. We found several examples of cross-sectoral connections, potentially improving access to pain care according to need at the local level. The most variable and least well-developed responses were to the question on equitable delivery of care, demonstrating need to improve delivery of equitable approaches and strategies to pain care.</p><p><strong>Conclusions: </strong>We used FOI requests to collect data on chronic pain staffing capacity showing considerable variation across Scotland. There are limitations to this method; it is likely that our findings do not show a complete picture, rather useful insights into activities and provisions of services for pain care across Scotland.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637251413581"},"PeriodicalIF":2.8,"publicationDate":"2026-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12779529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atieh Sadr, Ali Gholamrezaei, Amy G McNeilage, Cameron L Randall, Flavia P Kapos, Christopher C Peck, Claire E Ashton-James
{"title":"Psychological contributors to pain before, during, and after endodontic procedures: A scoping review.","authors":"Atieh Sadr, Ali Gholamrezaei, Amy G McNeilage, Cameron L Randall, Flavia P Kapos, Christopher C Peck, Claire E Ashton-James","doi":"10.1177/20494637251408718","DOIUrl":"10.1177/20494637251408718","url":null,"abstract":"<p><strong>Background: </strong>Despite an increasingly biopsychosocial approach to pain management in healthcare, limited research exists on psychological features in dentistry including endodontic-related pain. This study aimed to identify the scope of evidence on the relationship of psychological variables to pain associated with dentistry specifically endodontics, as a first step towards addressing them for treatment.</p><p><strong>Methods: </strong>This scoping review was conducted according to the JBI Manual for Evidence Synthesis. Literature searches were performed in MEDLINE, EMBASE, PsycINFO, Web of Science, Scopus, Cochrane, and CINAHL, alongside grey literature sources, including ProQuest, ClinicalTrials.gov, and conference materials, reference lists, medRxiv pre-prints, EBSCO theses, and data from clinical trial registers such as ClinicalTrials.gov and Cochrane trials (via Ovid) (from inception to February 2025). Two independent reviewers screened records, and data extraction was cross-verified. The protocol was registered on Open Science Framework (DOI: 10.17605/OSF.IO/FSRJP).</p><p><strong>Results: </strong>Forty eight studies were included. Twelve broad psychological constructs were evaluated in relation to pre, during, and post-endodontic pain: pain expectancies, positive treatment expectancies, depression, anxiety, positive and negative mood (affect), beliefs about pain, desire for control of dental treatments, perceptions of dentists, somatic focus or awareness, pain coping strategies, personality, and psychiatric diagnoses. Pre-procedural pain was most frequently linked to anxiety. Procedural and post-procedural pain was consistently associated with anxiety, pain expectations, depression, and pain beliefs.</p><p><strong>Conclusion: </strong>A variety of psychological factors have been investigated in relation to endodontic pain at different time-frames. Whilst associations between endodontic pain and psychological constructs were found, further research is needed to evaluate the strength of these associations, and the scope of evidence for interventions designed to address these psychological contributors to pain in dental practice. Identifying psychological contributors to endodontic pain can enhance pain prediction, patient communication, and clinical care strategies.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637251408718"},"PeriodicalIF":1.5,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12743013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Packham, Melanie Smith, Katherine Gerrard, Craig Murray
{"title":"Experiences of coping with and adjusting to phantom limb pain: An interpretative phenomenological analysis.","authors":"Anna Packham, Melanie Smith, Katherine Gerrard, Craig Murray","doi":"10.1177/20494637251405402","DOIUrl":"10.1177/20494637251405402","url":null,"abstract":"<p><p>This study explored the psychological sense-making of people with amputations towards their phantom limb pain. Interviews with eight participants were analysed using interpretative phenomenological analysis. Four themes were developed: (1) 'Everybody just thinks you're some kind of freak': Making personal and social sense of phantom limb pain; (2) 'If you talk about them, they seem to come': Perceiving phantom limb pain as an externalised threat; (3) 'The sooner you accept things, truthfully accept things, then life becomes better': Achieving acceptance; and (4) The unrecognised role of psychology in managing phantom limb pain. The findings indicate the importance of (1) education and validation for those who experience phantom limb pain, (2) education around the role psychology can have in managing with the pain, and (3) psychological interventions being available and offered to those with phantom limb pain.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637251405402"},"PeriodicalIF":1.5,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12695594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145758049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Margot Bedu, David Ogez, Jennifer Aramideh, Beáta Bőthe, Ariane Levesque, Émélie Rondeau, Anne-Frédérique Tessier, Michel Duval, Serge Sultan
{"title":"How professionals in pediatrics change the words they use to mitigate pain: A lexical description after a short hypnosis-based communication training.","authors":"Margot Bedu, David Ogez, Jennifer Aramideh, Beáta Bőthe, Ariane Levesque, Émélie Rondeau, Anne-Frédérique Tessier, Michel Duval, Serge Sultan","doi":"10.1177/20494637251403003","DOIUrl":"10.1177/20494637251403003","url":null,"abstract":"<p><strong>Background: </strong>Young patients who suffer from a pediatric condition are typically submitted to diverse and often repeated painful procedures. Theory and empirical studies suggest that communication styles used by healthcare professionals could mitigate such procedural pain. Recently, a hypnotic communication training (Rel@x) was developed with promising results. The present study aimed to describe how healthcare professionals change the words they use with patients after training.</p><p><strong>Methods: </strong>A nine-hour training in hypnosis-derived communication was offered to 78 volunteer healthcare professionals from a tertiary pediatric hospital, and 58 participated in the evaluative study. Participants were evaluated at baseline, immediately after the training, and 5 months later (39 ± 10 yrs, 52 women, 54 nurses). We used a video-recorded standardized simulation protocol of venipuncture, and five categories of words were derived. Word categories were corroborated in a validity study with 10 independent judges. We modeled pre-post-follow-up changes over time with latent growth curve models.</p><p><strong>Results: </strong>Following training, healthcare professionals used fewer words related to negative experiences (-51%) or medical procedures (-73%) and used more words referring to the relaxing and analgesic experience (+20%), and the specific techniques they had learned (Pleasant place +260%, Magic glove +582%). These changes were maintained at a proportion of 45-81% 5 months later. More change was observed among women and less experienced healthcare professionals.</p><p><strong>Conclusion: </strong>Results suggest that healthcare professionals exposed to a short, structured communication training aiming to mitigate pediatric pain durably adjust the language they use when performing a painful procedure. This is encouraging for future testing and implementation of hypnosis-derived communication training in healthcare providers.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637251403003"},"PeriodicalIF":1.5,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12675228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145702237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}