Global and regional trends and projections of chronic pain from 1990 to 2035: Analyses based on global burden of diseases study 2019.

IF 1.3 Q4 CLINICAL NEUROLOGY
Mengyi Zhu, Jiarui Zhang, Diefei Liang, Junxiong Qiu, Yuan Fu, Zhaopei Zeng, Jingjun Han, Junmeng Zheng, Liling Lin
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引用次数: 0

Abstract

Background: Chronic pain poses a significant public health challenge. We present the global and regional data on Prevalence, Incidence and Years Lived with Disability (YLDs) for Chronic pain from the Global burden of disease (GBD) study 2019 data and analyze their associations with Socio-demographic index (SDI), age, and gender, and the future trends from 2020 to 2035.

Methods: Regional trends in the burden of chronic pain and its association with age, gender, and SDI were assessed from 1990 to 2019. Joinpoint analysis was employed to describe trends in chronic pain burden across different SDI regions. Additionally, the Bayesian Age-Period-Cohort model (BAPC) was used for predicting future trends. Age-standardized rates (ASRs) of prevalence, incidence, and YLDs were employed to quantify the burden of chronic pain.

Results: Between 1990 and 2019, a significant increase was observed in global prevalence and YLDs rates of chronic pain. Higher rates were found among females, whereas a faster rise was noted among males. Notably, Low Back Pain (LBP) and Migraine accounted for predominant YLDs globally, particularly among those aged 75 and above. A notable prevalence of Tension-type Headache (TTH) was observed among younger populations. Furthermore, ASRs for chronic pain were highest in high-SDI regions. Projections suggest an increase in headache ASRs globally for both genders from 2020 to 2035.

Conclusion: From 1990 to 2019, the global burden of chronic pain increased significantly, with projections indicating a continued rise in headache burden over the next 15 years, underscoring the need for heightened attention to these issues.

1990 - 2035年全球和区域慢性疼痛趋势和预测:基于2019年全球疾病负担研究的分析
背景:慢性疼痛是一个重大的公共卫生挑战。我们介绍了2019年全球疾病负担(GBD)研究中慢性疼痛的患病率、发病率和残疾生活年数(YLDs)的全球和区域数据,并分析了它们与社会人口指数(SDI)、年龄和性别的关系,以及2020年至2035年的未来趋势。方法:评估1990年至2019年慢性疼痛负担的区域趋势及其与年龄、性别和SDI的关系。采用关节点分析来描述不同SDI地区慢性疼痛负担的趋势。此外,贝叶斯年龄-时期-队列模型(BAPC)用于预测未来趋势。采用流行率、发病率和YLDs的年龄标准化率(ASRs)来量化慢性疼痛的负担。结果:1990年至2019年期间,慢性疼痛的全球患病率和死亡率显著上升。女性的发病率更高,而男性的发病率上升得更快。值得注意的是,腰痛和偏头痛占全球主要的YLDs,特别是在75岁及以上的人群中。紧张型头痛(TTH)在年轻人群中显著流行。此外,慢性疼痛的asr在高sdi区域最高。预测表明,从2020年到2035年,全球范围内的头痛性asr病例不论男女都在增加。结论:从1990年到2019年,全球慢性疼痛负担显著增加,预测显示未来15年头痛负担将继续增加,强调需要高度关注这些问题。
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来源期刊
British Journal of Pain
British Journal of Pain CLINICAL NEUROLOGY-
CiteScore
3.20
自引率
11.10%
发文量
42
期刊介绍: British Journal of Pain is a peer-reviewed quarterly British journal with an international multidisciplinary Editorial Board. The journal publishes original research and reviews on all major aspects of pain and pain management. Reviews reflect the body of evidence of the topic and are suitable for a multidisciplinary readership. Where empirical evidence is lacking, the reviews reflect the generally held opinions of experts in the field. The Journal has broadened its scope and has become a forum for publishing primary research together with brief reports related to pain and pain interventions. Submissions from all over the world have been published and are welcome. Official journal of the British Pain Society.
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