Andrew Gorrie, Bethany McLennan, Emily Yeoh, Tiina Jaaniste
{"title":"Exercise testing in a paediatric chronic pain cohort - A cross-sectional observation study.","authors":"Andrew Gorrie, Bethany McLennan, Emily Yeoh, Tiina Jaaniste","doi":"10.1177/20494637261445408","DOIUrl":"https://doi.org/10.1177/20494637261445408","url":null,"abstract":"<p><strong>Background: </strong>The utility of exercise testing in an interdisciplinary paediatric chronic pain assessment is unknown. The aims of this study were to explore exercise testing results in a paediatric chronic pain cohort and associations with baseline patient-reported outcome measures (PROMs), including various measures of pain experience and functioning.</p><p><strong>Methods: </strong>There were 153 participants, aged 6-17 years, attending the Sydney Children's Hospital Interdisciplinary Chronic and Complex Pain Clinic with data analysed retrospectively. Exercise tests included the six-minute walk test (6MWT), plank, prone extension and pushups. Results were described and stratified by age, and Spearmen correlation coefficients (<i>r</i> <sub>s</sub>) were determined between baseline exercise testing results and PROMs, and between different exercise tests.</p><p><strong>Results: </strong>The 6MWT distances were greater in the younger subgroup, however, there were no other differences in exercise tests between age groups. Associations between baseline exercise testing results and baseline PROMs ranged from very weak to moderate (<i>r</i> <sub>s</sub>'s = .18-.40). Associations between different exercise testing results ranged from very weak to moderate (<i>r</i> <sub>s</sub>'s = .17-.52). The 6MWT, plank and pushups each had at least five weak to moderate associations with PROMs and the prone extension test had one weak association.</p><p><strong>Conclusions: </strong>Exercise testing results in a paediatric chronic pain cohort are presented, including with age stratification. The results of the current study suggest that exercise testing provides unique information to supplement other forms of assessment. There is a need for standardised exercise protocols with normative datasets, so that clinical and research findings are more comparable across settings.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261445408"},"PeriodicalIF":1.5,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13128793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147821231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fausto Morell-Ducos, Jennifer Samson, Jamie Smart, Xolani Dereck Gondongwe, Amanda C de C Williams
{"title":"Experience of opioid cessation after surgery in opioid-naïve patients in the United Kingdom: A qualitative study.","authors":"Fausto Morell-Ducos, Jennifer Samson, Jamie Smart, Xolani Dereck Gondongwe, Amanda C de C Williams","doi":"10.1177/20494637261443815","DOIUrl":"https://doi.org/10.1177/20494637261443815","url":null,"abstract":"<p><strong>Background: </strong>Opioid analgesia is frequently prescribed after surgery, with the expectation that patients will cease use within weeks, yet up to 25% of opioid-naïve patients may develop persistent postoperative opioid use. Opioid stewardship interventions are increasingly used to mitigate this risk, but little is known of the psychological factors influencing successful opioid cessation in the community after surgery in the UK.</p><p><strong>Aim: </strong>To identify psychological factors influencing opioid use and cessation after discharge following surgery in the UK.</p><p><strong>Design: </strong>Interviews with post-surgical patients 3 months after discharge; qualitative framework analysis summarised as themes.</p><p><strong>Methods: </strong>Opioid-naïve patients discharged on opioids after all-type surgery were invited three months later to a telephone interview that explored their experience of reducing opioids at home, and what influenced these decisions. Data were transcribed and qualitatively analysed.</p><p><strong>Results: </strong>48 participants were interviewed: all had ceased opioid use within one month of surgery. Four themes, comprising 15 subthemes, described diverse considerations: relationship with opioids - balance of benefits and risks; relationship with pain; relationship with clinicians; and views about addiction, including moral perspectives.</p><p><strong>Conclusion: </strong>Those interviewed made complex decisions on tapering opioids drawing on beliefs and previous experiences, relationships to healthcare, and prior experiences of pain. The themes identified lend further support, in the UK healthcare setting, to specific opioid stewardship interventions, especially patient education, pack-size limitation, and transitional pain services.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261443815"},"PeriodicalIF":1.5,"publicationDate":"2026-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13096016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Galligan, Rebecca Verity, Theresa Wiseman, Emma Briggs
{"title":"Cancer pain knowledge and attitudes of healthcare professionals: A systematic review of surveys and their measurement properties.","authors":"Martin Galligan, Rebecca Verity, Theresa Wiseman, Emma Briggs","doi":"10.1177/20494637261442745","DOIUrl":"https://doi.org/10.1177/20494637261442745","url":null,"abstract":"<p><strong>Background: </strong>Effective management of cancer-related pain (CRP) requires support from knowledgeable healthcare professionals. Existing literature states that healthcare professionals' knowledge of CRP is poor. However, there is no consistency in how knowledge and attitudes are assessed or the standards against which they are measured. This systematic review evaluates the cancer-related content and psychometric properties of surveys used to assess knowledge of CRP.</p><p><strong>Method: </strong>Using JBI methodology for Systematic Reviews of Measurement Properties, the search was conducted in MEDLINE, EMBASE, CINAHL and PsycINFO (limited to 2011-2024). Screening and extraction were completed by two researchers using the COVIDENCE system. The COSMIN Risk of Bias checklist was used to assess psychometric properties, and additional data were extracted on content feasibility.</p><p><strong>Results: </strong>A total of 1024 papers were identified, and 37 were included in the final analysis. Sixteen different surveys were found, with four being used in multiple studies. No survey was deemed superior, and all were rated poorly using the COSMIN Risk of Bias checklist. The CRP content within the surveys varied significantly, with none capturing the complexity of CRP. The feasibility of administering these surveys in practice was not reported in the studies examined.</p><p><strong>Conclusion: </strong>The wide variation in the design and content of surveys identified makes it difficult to assess the current state of healthcare professionals' knowledge of CRP. This raises questions about the validity and reliability of their conclusions, as they lack a robust evaluation of psychometric properties. Further research is needed to accurately assess healthcare professionals' knowledge of CRP.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261442745"},"PeriodicalIF":1.5,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13076462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors associated with disability in women with chronic pelvic pain: A cross-sectional study.","authors":"Natany Santos Martins, Gleiciane Aguiar Brito, Simony Lira Nascimento, Mayle Andrade Moreira","doi":"10.1177/20494637261432838","DOIUrl":"10.1177/20494637261432838","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to explore the factors associated with disability in women with chronic pelvic pain (CPP).</p><p><strong>Methods: </strong>This is a cross-sectional study conducted in Brazil with women with CPP, between 18 and 45 years old. Disability was measured using the World Health Organisation Disability Assessment Scale (WHODAS 2.0). Socioeconomic and clinical data were collected, and instruments to assess pain intensity and catastrophising, sexual function, kinesiophobia, depression, physical activity and the sit-to-stand test were applied. Correlations of Spearman, Student's t-test and multiple linear regression were used for data analysis (α = 0.05).</p><p><strong>Results: </strong>168 women with a median age of 36 (IQR 29 - 40) years were evaluated. Those with greater pain intensity and catastrophising, sexual dysfunction, kinesiophobia, depression, who do not practice regular physical activity and with worse performance in the sit-to-stand test had greater disability on correlation analysis. However, only pain catastrophising (β = 6.40; 95%CI 0.44 - 12.36) and depression (β = 12.03; 95%CI 6.61 - 17.45) were predictors of disability (p < 0.05) in the adjusted linear regression model.</p><p><strong>Conclusion: </strong>Our results indicate that psychosocial factors (pain catastrophising and depression) have a stronger relationship with disability than pain intensity or physical factors (sit to stand and physical activity). Therefore, all clinicians involved in the care of women with CPP could systematically assess and address pain catastrophising and depression as part of comprehensive management to prevent disability.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261432838"},"PeriodicalIF":1.5,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From childhood struggles to adult strains: A systematic review of the impact of adverse childhood experiences on psycho-emotional functioning, pain outcomes, and quality of life in populations experiencing chronic pain.","authors":"Angeliki Gkiouzeli, Marie-Jo Brennstuhl, Amélie Couraillon, Pierrick Poisbeau, Christine Rotonda, Cyril Tarquinio","doi":"10.1177/20494637261429225","DOIUrl":"10.1177/20494637261429225","url":null,"abstract":"<p><p>Adverse childhood experiences (ACEs) are well-documented risk factors for later health problems, such as chronic pain and mental illness. We aimed to synthesise the impact of childhood trauma on psycho-emotional disorders, pain perception and cognitions, and quality of life in individuals with chronic pain. A systematic review was conducted following PRISMA guidelines for systematic reviews and meta-analyses. Eligible studies were identified by searching PubMed, PsychINFO, Embase, and Web of Science, with publication dates from 1988 to April 2023. Inclusion criteria were formulated according to the PECOS framework, and relevant research articles were screened for inclusion. Evidence from 18 studies highlights the significant impact of ACEs (and their typologies) on patients' psycho-emotional well-being, pain outcomes, and overall quality of life, with a cumulative effect emerging. However, significant methodological limitations, such as the lack of standardised measures to classify childhood adversity, prevent us from drawing definitive conclusions about the reported associations. The findings underscore the importance of integrated approaches to pain management that centre on the patient's life history and psycho-emotional status. Future research should address current limitations to strengthen our understanding of the role of ACEs in chronic pain research.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261429225"},"PeriodicalIF":1.5,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12960269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reflections on suzetrigine and the evolving landscape of non-opioid analgesia.","authors":"Antonio Alcántara Montero","doi":"10.1177/20494637261430909","DOIUrl":"10.1177/20494637261430909","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261430909"},"PeriodicalIF":1.5,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12953157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lawrence Roux, Sylvia M Gustin, Toby Ro Newton-John
{"title":"A qualitative analysis of healthcare professionals' perspectives on goal adjustment in chronic pain.","authors":"Lawrence Roux, Sylvia M Gustin, Toby Ro Newton-John","doi":"10.1177/20494637261418200","DOIUrl":"10.1177/20494637261418200","url":null,"abstract":"<p><strong>Introduction: </strong>This qualitative study investigated clinician perspectives on the relevance and significance of goal adjustment in the treatment of chronic pain. Although a common experience for many people living with chronic pain, goal adjustment remains underexplored in the therapeutic literature. Exploring clinicians' experiences can optimize treatment strategies for individuals whose chronic pain imposes functional limitations, and where significant adjustments to important life aspirations are required.</p><p><strong>Methods: </strong>Semi-structured interviews were conducted with 14 experienced pain clinicians, including medical specialists, physiotherapists, and clinical psychologists. The interviews explored three areas: the relevance of goal adjustment in clinical practice, factors that enhance and hinder flexible goal adjustment, and treatment strategies for redirecting patient efforts towards alternative more viable aspirations. An inductive thematic analysis was performed to identify key themes from the data.</p><p><strong>Results: </strong>Clinicians unanimously endorsed the view that goal adjustment issues commonly occur when treating chronic pain. The thematic analysis highlighted the importance of flexible goal adjustment and the distress caused by letting go of goal ambitions. The consequences of problematic or inflexible goal adjustment are explored, along with barriers and facilitators of goal adjustment in chronic pain. Themes such as rigid self-identity, cognitive rigidity, limited understanding of chronic pain, and emotional distress were identified as barriers. The role of family, health professionals, and other social influences is also discussed. Therapeutic approaches emphasize realistic and meaningful goals, timing, rapport, trust, values-based goals, and validating distress.</p><p><strong>Discussion: </strong>The findings suggest that goal adjustment is a well-recognized component of chronic pain treatment. Experienced pain clinicians identified that the successful resolution of the challenges of goal adjustment and the implementation of effective strategies to adopt realistic expectations is critical for positive patient outcomes. This study underscores the importance of integrating goal adjustment frameworks into chronic pain management to enhance therapeutic efficacy.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261418200"},"PeriodicalIF":1.5,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146182991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason Luo, Mark Woodward, Manuela L Ferreira, Katie Harris
{"title":"Sex differences in the experience of pain in the UK Biobank cohort study.","authors":"Jason Luo, Mark Woodward, Manuela L Ferreira, Katie Harris","doi":"10.1177/20494637261418196","DOIUrl":"10.1177/20494637261418196","url":null,"abstract":"<p><strong>Objective: </strong>Chronic pain has been shown to be more prevalent among women than men. However, each person's experience of pain is shaped by a complex interplay of biological, psychological and social factors. The aim of this study was to summarise a comprehensive 'experience of pain' questionnaire in the UK Biobank and identify differences in the experience of chronic pain between females and males.</p><p><strong>Methods: </strong>This was an exploratory analysis of an online self-assessment questionnaire consisting of 128 questions related to UK Biobank participant's experience of pain that was administered in 2019. Data were summarised by sex, and chi-squared and <i>t</i>-tests were used to determine whether there were statistically significant differences between females and males.</p><p><strong>Results: </strong>About one-third of UK Biobank participants (167,183, 57% female) responded to the questionnaire. More females than males reported suffering from chronic pain (60.0% vs 51.5%). There was female predominance in 11 out of 14 medical conditions, particularly in osteoarthritis (35.6% females vs 24.5% males), migraine (25.0% vs 12.3%) and fibromyalgia (2.7% vs 0.7%). Female participants tended to report pain of greater severity and longer duration that more profoundly impairs their everyday functioning when compared to their male counterparts.</p><p><strong>Conclusion: </strong>A significant strength of our study is the large sample size, and the high detail of information captured about pain phenotypes, in which we found sex differences in chronic pain persist. We recommend future pain surveys collect sex-based pain conditions to enable better recognition of why sex differences in pain persist.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637261418196"},"PeriodicalIF":1.5,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12827042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}