British Journal of Pain最新文献

{"title":"Persistent post-discharge opioid use and opioid stewardship: A single-centre retrospective cohort study.","authors":"Sandra Hapca, Louise Peet, Christine Gibson, Andrea Harvey, Patrice Forget","doi":"10.1177/20494637241276106","DOIUrl":"10.1177/20494637241276106","url":null,"abstract":"<p><p>Persistent post-operative opioid use is a public health concern contributing to population morbidity and mortality. Opioid stewardship is a strategy adopted to rationalise opioid prescribing and limit harmful use. We describe persistent post-discharge opioid use rates and risk factors in a single-centre cohort and describe the opioid stewardship role of our Acute Pain Service (APS). We conducted a retrospective 4-year cohort study of inpatients referred to the APS and discharged with new strong opioids prescribed. We investigated persistent post-discharge opioid use rates, risk factors and patterns of opioid use after community follow-up by APS. We found that 24% of patients discharged with new strong opioids developed persistent opioid use. Risk factors associated with persistent post-discharge opioid use in our cohort included female sex (Odds Ratios [95% confidence interval], <i>p</i> value, OR: 1.89 [1.11-3.22], <i>p</i> = 0.019), pre-admission mental health history (OR: 2.85 [1.64-4.95], <i>p</i> < 0.001) and pre-admission opioid use (OR: 1.79 [1.03-3.11], <i>p</i> = 0.004). A smaller proportion of patients with APS follow-up in community developed persistent opioid use (22%) compared to those without (32%). We conclude that having opioids prescribed at time of discharge can result in persistent opioid use in up to a quarter of patients. The APS has an important protective role in rationalising opioid use in hospital but also following discharge. Development of further opioid stewardship policies is needed including improvement of patient and staff awareness and pre-operative assessment of patients with recognised risk factors.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"497-503"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of a novel multicomponent treatment in women with fibromyalgia: A randomized clinical trial.","authors":"Felipe Araya-Quintanilla, Celia Álvarez-Bueno, Iván Cavero-Redondo, Robinson Ramírez-Vélez, Walter Sepúlveda-Loyola, Héctor Gutiérrez-Espinoza","doi":"10.1177/20494637241293760","DOIUrl":"10.1177/20494637241293760","url":null,"abstract":"<p><strong>Background: </strong>Multicomponent treatment is commonly used. However, there are no studies that included graded motor imagery and therapeutic neuroscience education to multicomponent treatment for patients with fibromyalgia This study aims to compare the short-term effects (at 12 weeks) of a multicomponent treatment combined with graded motor imagery and therapeutic neuroscience education versus standard treatment in patients with FM.</p><p><strong>Methods: </strong>The study was a single-blinded randomized controlled trial. Sixty-five women with a clinical diagnosis of FM were randomly allocated (1:1) into two groups. The experimental group (<i>n</i> = 33) received a novel multicomponent treatment combined with graded motor imagery and neuroscience education. The control group (<i>n</i> = 32) received a standard treatment including pharmacotherapy and standard physician education. The primary outcome was pain intensity assessed with the Numeric Pain Rating Scale (NPRS). The secondary outcomes were changes in the Fibromyalgia Impact Questionnaire (FIQ), the Pain Catastrophizing Scale (PCS), the Tampa Scale of Kinesiophobia (TSK-17), and the Pittsburgh Sleep Quality Index (PSQI) scores. All outcomes were assessed at baseline and 12 weeks.</p><p><strong>Results: </strong>All of the participants completed the trial. The between-group mean differences at 12 weeks were: NPRS-1.18 points (95% confidence interval [CI] -0.4 to -1.8; η² = 0.47; <i>p</i> < .001); FIQ-16.21 points (95% CI -10.9 to -22.1; η² = 0.58; <i>p</i> < .001); PCS total domain -12.5 points (95% CI -7.2 to -17.8; η² = 0.61; <i>p</i> < .001); TSK-17-6.15 points (95% CI -3.5 to -8.7; η² = 0.52; <i>p</i> < .001); and PSQI-2.74 points (95% CI -1.4 to 4.0; η² = 0.54; <i>p</i> < .001). All differences were statistically significant in favor of the novel multicomponent treatment group and had a large effect size.</p><p><strong>Conclusions: </strong>In the short term, a novel multicomponent treatment, including graded motor imagery and neuroscience education, was an effective therapeutic intervention for improving clinical outcomes compared with standard treatment in women with FM. Additional studies are needed to support long-term clinical effectiveness in these patients.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"504-513"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The value of social relationships in the biopsychosocial model of pain.","authors":"Daniela Ghio, Sarah Peters","doi":"10.1177/20494637241297274","DOIUrl":"10.1177/20494637241297274","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"448-449"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do threats and reassurances reside in the biological, psychological or social domain? A qualitative study in adults and young people with chronic pain.","authors":"Hannah Kennedy, Daniel S Harvie, Michel W Coppieters","doi":"10.1177/20494637241263291","DOIUrl":"10.1177/20494637241263291","url":null,"abstract":"<p><strong>Objective: </strong>Understanding biopsychosocial contributions to a sensitised pain system is a key target of many pain management programs. The 'Protectometer' is a freely available educational tool that guides people with chronic pain to explore their personal threats and reassurances, identifying them as 'DIMs' (danger in me) or 'SIMs' (safety in me), to guide personalised pain management. This study aimed to explore common types of DIMs and SIMs, and examine differences between adults and young people.</p><p><strong>Materials and methods: </strong>A retrospective qualitative study was conducted. Written DIMs (<i>n</i> = 504) and SIMs (<i>n</i> = 711) were collected from 96 participants with chronic pain (77 adults aged 18-85 years; 19 young people aged 9-17 years) across 15 multidisciplinary pain management groups. DIMs and SIMs were transcribed and analysed using deductive content analysis.</p><p><strong>Results: </strong>Four overarching themes were identified: 'Engaging with the environment', 'In my body', 'My emotional health', and 'Activities and behaviours'. Similarities in SIMs were found, with the greatest proportion of SIMs in the social domain (49% adults; 47% young people). While adult DIMs were fairly evenly spread across the biological (37%), psychological (27%) and social domains (36%), young people's DIMs were predominantly in the psychological (44%) and social (43%) domains.</p><p><strong>Discussion: </strong>These findings provide insights into common threats and reassurances people in pain perceive, and revealed age-related differences in biopsychosocial contributions to pain and pain relief. Findings also highlight the importance of social-based interventions as part of pain management therapies for both adults and young people.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"472-481"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Botulinum toxin: Should we reconsider its place in the treatment of neuropathic pain?","authors":"Paul Bhalla","doi":"10.1177/20494637241282323","DOIUrl":"10.1177/20494637241282323","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"18 5","pages":"386-387"},"PeriodicalIF":2.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11451518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What influences post-operative opioid requirements for tibial fractures?","authors":"James Zhang, Aaron Limonard, Florence Bradshaw, Ishrat Hussain, Maša Josipović, Matija Krkovic","doi":"10.1177/20494637241261013","DOIUrl":"10.1177/20494637241261013","url":null,"abstract":"<p><strong>Introduction: </strong>Currently there are few opioid prescribing guidelines for orthopaedic fractures. Long-term post-surgical analgesia requirements, understandably, vary between orthopaedic cases. Our study aims to provide detailed information to clinicians and policy makers, on the opioid requirement associations for patients sustaining tibial fractures.</p><p><strong>Methods: </strong>This study reviewed all patients sustaining an isolated tibial fracture at a major trauma centre that were operated on within 1 month of injury, from 2015 to 2022. The total opioid dosage used each month in morphine milligrams equivalents (MME) and the number of days opioids were used each month, within the first-year post-surgery were collected, representing the strength and coverage of opioid analgesia in the post-operative stage, respectively. We compared opioid strength and coverage requirements with types of definitive fracture fixations, location, fracture type and concurrent patient medical comorbidities to assess for any trends.</p><p><strong>Results: </strong>A total of 1814 patients sustaining a combined of 1970 fractures were included in the study. Tibial plateau fractures had the highest opioid strength and coverage requirements in each month and the entire year (<i>p</i> < .05). Across all fracture locations, Ex Fix frame showed higher opioid strength and coverage requirements compared to both IM nailing and plate ORIF. With regard to opioid coverage in the presence of specific comorbidities, only chronic kidney disease (quotient: 1.37, 95% Confidence interval [95%CI] = 1.19-1.55, <i>p</i> = .002) and hypertension (quotient: 1.34, 95%CI = 1.14-1.53, <i>p</i> = .009) showed significance at the 1-year overall level. For opioid strength, Chronic Kidney Disease (quotient: 1.72, 95%CI = 1.41-2.03 <i>p</i> = .005) and COPD (quotient: 1.90, 95%CI = 1.44-2.36, <i>p</i> = .014), show significance at the 1-year overall level.</p><p><strong>Conclusion: </strong>Our study details opioid requirements post-surgery amongst tibial fractures with subgroup analysis assessing opioid needs amongst specific fracture locations, types, surgical techniques and medical comorbidities. This framework aids clinicians in anticipating rehabilitation and assists in risk stratifying patients at injury onset.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"18 5","pages":"433-443"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11440535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrathecal drug delivery for the management of pain and spasticity in adults: British Pain Society's recommendations for best clinical practice.","authors":"Sam Eldabe, Rui Duarte, Simon Thomson, Stana Bojanic, Paul Farquhar-Smith, Somnath Bagchi, Lis Farquhar, Bill Wetherill, Sue Copley","doi":"10.1177/20494637241280356","DOIUrl":"10.1177/20494637241280356","url":null,"abstract":"<p><p>The British Pain Society updated their recommendations on intrathecal drug delivery (ITDD) for the management of pain and spasticity in adults. The recommendations are primarily evidence based but where necessary comprise the consensus opinion of the working group. The recommendations are accompanied by information for patients and their carers, intended to inform and support patients in their decision making. The updated guidance includes recent evidence base of ITDD use in pain and spasticity, address the issues of drug pump compatibility following the latest manufacturer and Medicines and Healthcare products Regulatory Agency (MHRA) recommendations as well as provide an update on the indications and complication management particularly endocrine complications and intrathecal granuloma formation.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":" ","pages":"20494637241280356"},"PeriodicalIF":1.3,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prehabilitation: The underutilised weapon for chronic pain management.","authors":"Lydia V Tidmarsh, Richard Harrison, Katherine A Finlay","doi":"10.1177/20494637241250239","DOIUrl":"10.1177/20494637241250239","url":null,"abstract":"<p><strong>Objective: </strong>Prehabilitation encompasses preparatory clinical intervention(s) delivered during the period between diagnosis and treatment commencement. Despite widespread successful usage preoperatively, <i>psychological</i> prehabilitation is neglected in outpatient chronic pain management. Although pain management waitlists are associated with treatment attrition and psychological and physical decline, this time window is underutilised in preventing escalation. Waitlists present an under-explored opportunity to 'prehabilitate' patients waiting for treatment. This topical review aimed to: (1) examine the effectiveness of psychological prehabilitation for pain services; (2) evaluate the psychological and physical decline associated with waiting for pain management; (3) highlight key psychological prehabilitative targets for increasing treatment engagement; (4) promote pain management psychological prehabilitation within personalised pain medicine, building recommendations for future interventions.</p><p><strong>Methods: </strong>Studies regarding the impact of waitlists and prehabilitation for chronic pain were reviewed.</p><p><strong>Results: </strong>Findings demonstrated that the psychological constructs of patient expectations, health locus of control, self-efficacy and pain catastrophizing dynamically influence attrition, treatment engagement and outcomes while waiting. These constructs are amenable to change, emphasising their potential utility within a targeted waitlist intervention.</p><p><strong>Conclusions: </strong>Prehabilitating chronic pain patients towards treatment engagement could circumvent cycles of failed treatment seeking, preventing psychological and physical decline, and reducing healthcare utilisation. Utilising the waitlist to identify psychosocial risk factors (external health locus of control, low self-efficacy and high pain catastrophizing) would identify <i>who</i> requires additional support to prevent increased risk of treatment failure, enhancing personalised care before prescribed treatment is accessed. This review cements the urgent need for pain services to engage proactively with prehabilitation innovation.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"18 4","pages":"354-364"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience of compassion-based practice in mindfulness for health for individuals with persistent pain.","authors":"Callum Gray, Fergal Jones, Alessio Agostinis, Julia Morris","doi":"10.1177/20494637241232555","DOIUrl":"10.1177/20494637241232555","url":null,"abstract":"<p><strong>Purpose of the study: </strong>Research indicates that acquiring compassion is an integral part to positive outcomes to Mindfulness-based interventions (MBI), yet there is both theoretic and empirical literature suggesting that people with persistent pain are more likely to experience challenges and distress when engaging compassion-based practices. Mindfulness for Health is a standardised MBI for people with persistent pain and health conditions. This study sought to explore the positive, neutral and difficult experiences of compassion-based practice and meditation for participants in Mindfulness for Health to further understand implications and risks for participants of MBI's.</p><p><strong>Method and design: </strong>A qualitative design using Interpretative Phenomenological Analysis was applied to explore how participants understood of the experience of compassion-based practice and the meaning they gave to it. Eight participants who had completed the Mindfulness for Health from four separate groups were interviewed about their experience.</p><p><strong>Results: </strong>Five master themes were identified 'turning away from self-with-pain', 'self-with-pain experienced as shameful', 'facilitating change', 'turning towards self-with-pain', and 'accepting self'. Participants identified both perceived positive changes and difficult emotional experiences during the meditation practice, which they related to the context of compassion in their past and present life.</p><p><strong>Conclusions: </strong>Developing compassion is an important part of Mindfulness for Health, which is salient for participants as both a challenging and potentially valuable experience. Acquisition of mindfulness skills, supporting group dynamics and modelling compassion are understood as helpful in overcoming personal barriers and challenging experiences. Further research is needed to understand processes involved and explore the experience of non-completers.</p>","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"18 4","pages":"337-353"},"PeriodicalIF":1.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interaction between psychological factors and conditioned pain modulation.","authors":"Kristian Kjær-Staal Petersen","doi":"10.1177/20494637241263306","DOIUrl":"10.1177/20494637241263306","url":null,"abstract":"","PeriodicalId":46585,"journal":{"name":"British Journal of Pain","volume":"18 4","pages":"312-313"},"PeriodicalIF":2.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}