Clinical and Experimental Reproductive Medicine-CERM最新文献

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Impact of vitamin D supplementation as COVID-19 vaccine adjuvant on sperm parameters and sex hormones in men with idiopathic infertility: Two separate pre-post studies. 补充维生素 D 作为 COVID-19 疫苗佐剂对特发性不育男性精子参数和性激素的影响:两项独立的前后研究
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-06-01 Epub Date: 2024-01-24 DOI: 10.5653/cerm.2023.06464
Mahtab Zarepoor, Alireza Nazari, Soheila Pourmasumi
{"title":"Impact of vitamin D supplementation as COVID-19 vaccine adjuvant on sperm parameters and sex hormones in men with idiopathic infertility: Two separate pre-post studies.","authors":"Mahtab Zarepoor, Alireza Nazari, Soheila Pourmasumi","doi":"10.5653/cerm.2023.06464","DOIUrl":"10.5653/cerm.2023.06464","url":null,"abstract":"<p><strong>Objective: </strong>Vitamin D deficiency is a major problem for human health worldwide. The mechanisms of vitamin D in the male reproductive system are unknown. After coronavirus disease 2019 (COVID-19) vaccines were developed, doubts were raised about their possible effects on male fertility. Based on vitamin D's function in the immune system, its potential role as an adjuvant for COVID-19 vaccines is intriguing. The aims of this study were to assess the effects of vitamin D first on sperm parameters and sex hormones, and then as an immune adjuvant on sperm parameters and sex hormones after study participants had received their second doses of COVID-19 vaccines.</p><p><strong>Methods: </strong>Phase 1 (before the COVID-19 pandemic) included 72 men with idiopathic infertility, and phase 2 had 64 participants who received two doses of COVID-19 vaccines. Both groups were instructed to take 50,000 IU of vitamin D twice monthly for 3 months. Sperm parameters and sex hormones were assessed pre- and post-supplementation.</p><p><strong>Results: </strong>Regular vitamin D intake for 3 months significantly increased the participants' vitamin D levels (p=0.0001). Both phases showed a positive correlation between vitamin D intake and sperm parameters. Vaccination had no negative effects on sperm parameters and sex hormones. Vitamin D was associated with follicle-stimulating hormone (p=0.02) and testosterone (p=0.0001) in phase 2 after treatment.</p><p><strong>Conclusion: </strong>Our results support vitamin D supplementation as an immune adjunct to COVID-19 vaccination for improving sperm parameters and hormone levels. COVID-19 vaccination is not harmful for male fertility potential, and vitamin D is an effective factor for male fertility.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"125-134"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patterns of proliferation and fibrosis in a rat model of endometriosis following administration of Allium cepa. 服用薤白后子宫内膜异位症大鼠模型的增殖和纤维化模式。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-06-01 Epub Date: 2024-01-24 DOI: 10.5653/cerm.2023.06261
Hakan Kula, Orkun Ilgen, Sefa Kurt, Filiz Yılmaz
{"title":"Patterns of proliferation and fibrosis in a rat model of endometriosis following administration of Allium cepa.","authors":"Hakan Kula, Orkun Ilgen, Sefa Kurt, Filiz Yılmaz","doi":"10.5653/cerm.2023.06261","DOIUrl":"10.5653/cerm.2023.06261","url":null,"abstract":"<p><strong>Objective: </strong>Endometriosis is a common gynecological disease among reproductive-age women. Numerous hypotheses exist regarding the pathogenesis of endometriosis. In Turkey, the consumption of Allium cepa (commonly known as the \"onion cure\") is a popular treatment employed to alleviate a variety of gynecological disorders.</p><p><strong>Methods: </strong>In this study, our objective was to assess the therapeutic mechanisms of the onion bulb A. cepa using an autologous endometriosis model in Sprague-Dawley rats. Previous research has shown that A. cepa possesses anti-inflammatory, antioxidant, and antiapoptotic properties. We evaluated the pathological condition of endometriotic implants by employing hematoxylin-eosin staining and Ki67 immunohistochemistry analysis. Transforming growth factor-beta 1 (TGF-β1) and alpha-smooth muscle actin (α-SMA) have been identified as profibrotic markers that are highly overexpressed in endometriotic tissues relative to eutopic endometrial tissue. Furthermore, TGF-β1 influences the differentiation and progression of endometriosis. To quantify profibrotic activity, we measured TGF-β1 and α-SMA using the immunosorbent assay method.</p><p><strong>Results: </strong>Lower histologic evaluation scores for endometriotic implants were observed in the group receiving high-dose A. cepa relative to the other groups. Ki67 expression was reduced following the high-dose A. cepa regimen, which consisted of 30% A. cepa and 70% normal feed. However, no statistically significant differences in TGF-β1 or α-SMA levels were observed among the groups (p=0.7 and p=0.778, respectively).</p><p><strong>Conclusion: </strong>The findings suggest that A. cepa could serve as a therapeutic agent in endometriosis treatment, as evidenced by the reduction in proliferative potential. Nevertheless, A. cepa was not associated with significantly lower levels of endometriosis-associated TGF-β1 or α-SMA.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"112-119"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phycocyanin alleviates alcohol-induced testicular injury in male Wistar rats. 植物花青素可减轻酒精对雄性 Wistar 大鼠睾丸的损伤。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-06-01 Epub Date: 2024-01-17 DOI: 10.5653/cerm.2023.06422
Oumayma Boukari, Soumaya Ghoghbane, Wahid Khemissi, Thalja Lassili, Olfa Tebourbi, Khemais Ben Rhouma, Mohsen Sakly, Dorsaf Hallegue
{"title":"Phycocyanin alleviates alcohol-induced testicular injury in male Wistar rats.","authors":"Oumayma Boukari, Soumaya Ghoghbane, Wahid Khemissi, Thalja Lassili, Olfa Tebourbi, Khemais Ben Rhouma, Mohsen Sakly, Dorsaf Hallegue","doi":"10.5653/cerm.2023.06422","DOIUrl":"10.5653/cerm.2023.06422","url":null,"abstract":"<p><strong>Objective: </strong>Given the noteworthy implications of alcohol consumption and its association with male infertility, there has been a notable focus on investigating natural alternatives to mitigate its adverse effects. Thus, this study was conducted to assess the potential protective effect of phycocyanin extract derived from the blue algae Arthrospira (Spirulina) platensis against ethanol-induced oxidative stress, disturbances in testicular morphology, and alterations in sperm production.</p><p><strong>Methods: </strong>Male rats were divided into four groups (five rats each): the control group received a saline solution, the ethanol exposed group (EtOH) was subjected to intraperitoneal injections of 10 mL/kg of ethanol solution at a concentration of 38% (v/v), the phycocyanin alone treated group (P) received oral administration of phycocyanin at a dosage of 50 mg/kg, and the phycocyanin-cotreated group (PE) was given oral phycocyanin followed by ethanol injections. All treatments were administered over a period of 14 days.</p><p><strong>Results: </strong>Our findings demonstrated that ethanol exposure induced reproductive toxicity, characterized by reduced sperm production and viability, alterations in testicular weight and morphology, increased lipid peroxidation levels, and elevated oxidative enzyme activity. In addition, the ethanol-intoxicated group showed perturbations in serum biochemical parameters. However, the simultaneous exposure to ethanol and phycocyanin exhibited a counteractive effect against ethanol toxicity.</p><p><strong>Conclusion: </strong>The results showed that supplementation of phycocyanin prevented oxidative and testicular morphological damage-induced by ethanol and maintained normal sperm production, and viability.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"102-111"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genomic aspects in reproductive medicine. 生殖医学的基因组方面。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-06-01 Epub Date: 2024-01-24 DOI: 10.5653/cerm.2023.06303
Minyeon Go, Sung Han Shim
{"title":"Genomic aspects in reproductive medicine.","authors":"Minyeon Go, Sung Han Shim","doi":"10.5653/cerm.2023.06303","DOIUrl":"10.5653/cerm.2023.06303","url":null,"abstract":"<p><p>Infertility is a complex disease characterized by extreme genetic heterogeneity, compounded by various environmental factors. While there are exceptions, individual genetic and genomic variations related to infertility are typically rare, often family-specific, and may serve as susceptibility factors rather than direct causes of the disease. Consequently, identifying the cause of infertility and developing prevention and treatment strategies based on these factors remain challenging tasks, even in the modern genomic era. In this review, we first examine the genetic and genomic variations associated with infertility, and subsequently summarize the concepts and methods of preimplantation genetic testing in light of advances in genome analysis technology.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"91-101"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The protective effect of zinc oxide and selenium oxide nanoparticles on the functional parameters of rat sperm during vitrification. 氧化锌和氧化硒纳米颗粒对大鼠精子玻璃化过程中功能参数的保护作用。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-03-01 Epub Date: 2023-12-01 DOI: 10.5653/cerm.2023.06079
Nafiseh Tavakolpoor Saleh, Zohreh Hosseinzadeh, Narges Gholami Banadkuki, Maryam Salehi Novin, Sanaz Saljooghi Zaman, Tohid Moradi Gardeshi
{"title":"The protective effect of zinc oxide and selenium oxide nanoparticles on the functional parameters of rat sperm during vitrification.","authors":"Nafiseh Tavakolpoor Saleh, Zohreh Hosseinzadeh, Narges Gholami Banadkuki, Maryam Salehi Novin, Sanaz Saljooghi Zaman, Tohid Moradi Gardeshi","doi":"10.5653/cerm.2023.06079","DOIUrl":"10.5653/cerm.2023.06079","url":null,"abstract":"<p><strong>Objective: </strong>While sperm freezing (cryopreservation) is an effective method for preserving fertility, it can potentially harm the structure and function of sperm due to an increase in the production of reactive oxygen species. This study aimed to assess the impact of zinc oxide nanoparticles (ZnONPs) and selenium oxide nanoparticles (SeONPs) on various sperm functional parameters, including motility, plasma membrane integrity (PMI), mitochondrial membrane potential (MMP), acrosome membrane integrity (ACi), and malondialdehyde (MDA) levels.</p><p><strong>Methods: </strong>Semen samples were collected from 20 Albino Wistar rats. These samples were then divided into six groups: fresh, cryopreservation control, and groups supplemented with SeONPs (1, 2, 5 μg/mL) and ZnONPs (0.1, 1, 10 μg/mL).</p><p><strong>Results: </strong>Statistical analysis revealed that all concentrations of SeONPs increased total motility and progressive reduction of MDA levels compared to the cryopreservation control group (p<0.05). However, supplementation with ZnONPs did not affect these parameters (p>0.05). Conversely, supplements of 1 and 2 μg/mL SeONPs and 1 μg/mL ZnONPs contributed to the improvement of PMI and ACi (p<0.05). Yet, no significant change was observed in MMP with any concentration of SeONPs and ZnONPs compared to the cryopreservation control group (p>0.05).</p><p><strong>Conclusion: </strong>The findings suggest that optimal concentrations of SeONPs may enhance sperm parameters during the freezing process.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"20-27"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of prior cesarean delivery on the outcomes of intracytoplasmic sperm injection. 剖腹产对卵胞浆内单精子注射结果的影响。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-03-01 Epub Date: 2024-01-12 DOI: 10.5653/cerm.2023.06163
Suzan Atteya Gewida, Mohamed Salah Eldeen Abd Rabbo, Mohammed Abd Elmoety El Samra, Hesham Mahmoud Adel Abdel Moneim
{"title":"Effect of prior cesarean delivery on the outcomes of intracytoplasmic sperm injection.","authors":"Suzan Atteya Gewida, Mohamed Salah Eldeen Abd Rabbo, Mohammed Abd Elmoety El Samra, Hesham Mahmoud Adel Abdel Moneim","doi":"10.5653/cerm.2023.06163","DOIUrl":"10.5653/cerm.2023.06163","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted to investigate the impact of previous delivery mode on pregnancy outcomes in patients with secondary infertility after frozen-thawed embryo transfer.</p><p><strong>Methods: </strong>This prospective observational study included 140 patients experiencing secondary infertility. Of these, 70 patients had a previous cesarean delivery (CD), while the remaining 70 patients had a previous normal vaginal delivery (NVD). The primary outcome was the implantation rate. The secondary outcomes included rates of clinical pregnancy, chemical pregnancy, miscarriage, and ectopic pregnancy.</p><p><strong>Results: </strong>The comparison of all fertility outcomes between the two groups revealed no statistically significant differences. The implantation rate was 40.4% in the CD group and 41.7% in the NVD group (p=0.842). The clinical pregnancy rate was 50% in the CD group and 49.3% in the NVD group (p=0.932), while the chemical pregnancy rate was 14.6% in the CD group and 19% in the NVD group (p=0.591). The miscarriage rates in the CD and NVD groups were 20% and 17.6%, respectively (p=0.803). One case of tubal ectopic pregnancy occurred in the NVD group (1.4%).</p><p><strong>Conclusion: </strong>The mode of prior delivery did not significantly impact pregnancy outcomes following frozen-thawed embryo transfer.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"63-68"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blastocyst formation in vitrified-warmed preimplantation embryos derived from vitrified-warmed oocytes in a mouse model. 在小鼠模型中,从玻璃化温育卵母细胞中提取的玻璃化温育植入前胚胎的囊胚形成。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-03-01 Epub Date: 2024-02-29 DOI: 10.5653/cerm.2023.06499
Yeon Hee Hong, Byung Chul Jee
{"title":"Blastocyst formation in vitrified-warmed preimplantation embryos derived from vitrified-warmed oocytes in a mouse model.","authors":"Yeon Hee Hong, Byung Chul Jee","doi":"10.5653/cerm.2023.06499","DOIUrl":"10.5653/cerm.2023.06499","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to use a mouse model to investigate the blastocyst formation rate in vitrified-warmed embryos derived from vitrified-warmed oocytes.</p><p><strong>Methods: </strong>Metaphase II oocytes obtained from BDF1 mice were vitrified and warmed, followed by fertilization with epididymal sperm. On day 3, a total of 176 embryos, at either the eight-cell or the morula stage, were vitrified-warmed (representing group 1). For group 2, 155 embryos at the same developmental stages were not vitrified, but rather were directly cultured until day 5. Finally, group 3 included day-5 blastocysts derived from fresh oocytes, which served as fresh controls. The primary outcome measured was the rate of blastocyst formation per day-3 embryo at the eight-cell or morula stage.</p><p><strong>Results: </strong>The rates of blastocyst formation per day-3 embryo were comparable between groups 1 and 2, at 64.5% and 69.7%, respectively (p>0.05). The formation rates of good-quality blastocysts (expanded, hatching, or hatched) were also similar for groups 1 and 2, at 35.5% and 43.2%, respectively (p>0.05). For the fresh oocytes (group 3), the blastocyst formation rate was 75.5%, which was similar to groups 1 and 2. However, the rate of good-quality blastocyst formation in group 3 was 57.3%, significantly exceeding those of group 1 (p=0.001) and group 2 (p=0.023).</p><p><strong>Conclusion: </strong>Regarding developmental potential to the blastocyst stage, vitrified-warmed day-3 embryos originating from vitrified-warmed oocytes demonstrated comparable results to non-vitrified embryos from similar oocytes. These findings indicate that day-3 embryos derived from vitrified-warmed oocytes can be effectively cryopreserved without incurring cellular damage.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":"51 1","pages":"57-62"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preferred strategy for euploid single embryo transfer in advanced maternal age: Fresh versus frozen. 高龄产妇优生单胚胎移植的首选策略:新鲜胚胎与冷冻胚胎
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-03-01 Epub Date: 2024-01-24 DOI: 10.5653/cerm.2023.06233
Fatma Ozdemir, Gokalp Oner, Semra Kahraman, Yucel Sahin, Hakan Yelke
{"title":"Preferred strategy for euploid single embryo transfer in advanced maternal age: Fresh versus frozen.","authors":"Fatma Ozdemir, Gokalp Oner, Semra Kahraman, Yucel Sahin, Hakan Yelke","doi":"10.5653/cerm.2023.06233","DOIUrl":"10.5653/cerm.2023.06233","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to compare fresh and frozen-thawed euploid blastocyst transfer protocols following preimplantation genetic screening (PGS) in cases of advanced maternal age.</p><p><strong>Methods: </strong>A total of 330 patients were examined retrospectively. PGS was performed on the embryos of 146 patients for whom fresh transfers were chosen. In contrast, frozen-thawed euploid single embryo transfer (ET) was selected after PGS for 184 patients, and their embryos were vitrified. The percentage of euploid embryos and rates of implantation, pregnancy, and pregnancy continuity, as well as clinical and biochemical abortion rates, were compared.</p><p><strong>Results: </strong>The numbers of retrieved oocytes, metaphase II oocytes, and fertilized ova were greater in the frozen-thawed group. The percentages of euploid embryos were comparable between the fresh and frozen-thawed groups (32% vs. 34.8%, respectively). The rates of implantation (46.6%vs. 62.5%), pregnancy (50% vs. 66.8%), ongoing pregnancy (38.4% vs. 53.8%), and live birth percentage (37.0% vs. 53.8%) were significantly higher in the frozen-thawed group. However, no significant differences were found in the clinical and biochemical abortion rates.</p><p><strong>Conclusion: </strong>The use of frozen-thawed single euploid ET is associated with increased implantation and pregnancy rates compared to fresh single euploid ET with PGS.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"85-90"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139541690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detrimental impact of cell phone radiation on sperm DNA integrity. 手机辐射对精子 DNA 完整性的有害影响
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-03-01 Epub Date: 2024-01-24 DOI: 10.5653/cerm.2023.06121
Yeganeh Koohestanidehaghi, Mohammad Ali Khalili, Fatemeh Dehghanpour, Mohammad Seify
{"title":"Detrimental impact of cell phone radiation on sperm DNA integrity.","authors":"Yeganeh Koohestanidehaghi, Mohammad Ali Khalili, Fatemeh Dehghanpour, Mohammad Seify","doi":"10.5653/cerm.2023.06121","DOIUrl":"10.5653/cerm.2023.06121","url":null,"abstract":"<p><p>Radiofrequency electromagnetic radiation (RF-EMR) from various sources may impact health due to the generation of frequency bands. Broad pulses emitted within frequency bands can be absorbed by cells, influencing their function. Numerous laboratory studies have demonstrated that mobile phones-generally the most widely used devices-can have harmful effects on sex cells, such as sperm and oocytes, by producing RF-EMR. Moreover, some research has indicated that RF-EMR generated by mobile phones can influence sperm parameters, including motility, morphology, viability, and (most critically) DNA structure. Consequently, RF-EMR can disrupt both sperm function and fertilization. However, other studies have reported that exposure of spermatozoa to RF-EMR does not affect the functional parameters or genetic structure of sperm. These conflicting results likely stem from differences among studies in the duration and exposure distance, as well as the species of animal used. This report was undertaken to review the existing research discussing the effects of RF-EMR on the DNA integrity of mammalian spermatozoa.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"13-19"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Criteria for implementing artificial intelligence systems in reproductive medicine. 生殖医学人工智能系统实施标准。
IF 1.8
Clinical and Experimental Reproductive Medicine-CERM Pub Date : 2024-03-01 Epub Date: 2023-12-01 DOI: 10.5653/cerm.2023.06009
Enric Güell
{"title":"Criteria for implementing artificial intelligence systems in reproductive medicine.","authors":"Enric Güell","doi":"10.5653/cerm.2023.06009","DOIUrl":"10.5653/cerm.2023.06009","url":null,"abstract":"<p><p>This review article discusses the integration of artificial intelligence (AI) in assisted reproductive technology and provides key concepts to consider when introducing AI systems into reproductive medicine practices. The article highlights the various applications of AI in reproductive medicine and discusses whether to use commercial or in-house AI systems. This review also provides criteria for implementing new AI systems in the laboratory and discusses the factors that should be considered when introducing AI in the laboratory, including the user interface, scalability, training, support, follow-up, cost, ethics, and data quality. The article emphasises the importance of ethical considerations, data quality, and continuous algorithm updates to ensure the accuracy and safety of AI systems.</p>","PeriodicalId":46409,"journal":{"name":"Clinical and Experimental Reproductive Medicine-CERM","volume":" ","pages":"1-12"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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