Jornal Brasileiro de Reproducao Assistida最新文献

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Adrenergic effect on women's blood neutrophil oxidative activity the first day after delivery. 肾上腺素能对妇女产后第一天血液中性粒细胞氧化活性的影响。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240025
Oksana Olegovna Zaitseva, Victor Ivanovich Tsirkin, Inna Gennadievna Paturova, Tatiana Vitalievna Polezhaeva, Olga Nurzadinovna Solomina, Andrey Nikolaevich Khudyakov, Marta Igorevna Sergushkina, Svetlana Leonidovna Dmitrieva
{"title":"Adrenergic effect on women's blood neutrophil oxidative activity the first day after delivery.","authors":"Oksana Olegovna Zaitseva, Victor Ivanovich Tsirkin, Inna Gennadievna Paturova, Tatiana Vitalievna Polezhaeva, Olga Nurzadinovna Solomina, Andrey Nikolaevich Khudyakov, Marta Igorevna Sergushkina, Svetlana Leonidovna Dmitrieva","doi":"10.5935/1518-0557.20240025","DOIUrl":"10.5935/1518-0557.20240025","url":null,"abstract":"<p><strong>Objective: </strong>Recent studies have described a significant role for neutrophils in reproductive processes and their participation in the preparation of the cervix for childbirth and the activation of labor, in the postpartum involution of the uterus, and in the occurrence of preeclampsia. This study aimed to assess the formation of free radicals by neutrophils in the blood of women on the first day after childbirth and to characterize the adrenergic effect on this process.</p><p><strong>Methods: </strong>Venous blood samples from 100 female volunteers aged 26-32 years who had 2 or 3 full-term deliveries were collected and analyzed. Various adrenergic compounds were considered (agonists alphaand betaadrenoreceptors, adrenoblockers). The intensity of the respiratory burst of neutrophils and the effect of adrenergic substances on them were assessed with latex-induced luminol-dependent chemiluminescence.</p><p><strong>Results: </strong>Neutrophil activity depends on the stage of the woman's reproductive process: it decreases during pregnancy, reaches the lowest values during childbirth, and increases significantly in the first hours after childbirth. On the first day after childbirth, alpha-1-adrenergic receptors are highly active in neutrophils, through which NADP-H-oxidase is activated and activated oxygen species are formed. At the same time, alphaor beta-agonists inhibit the radical activity of cells.</p><p><strong>Conclusions: </strong>Latex-induced oxidative burst of female blood neutrophils correlates with the stage of the reproductive process. Stressful conditions in the postpartum period can suppress the ability of neutrophils to release reactive oxygen species, which increases the risk of postpartum infections.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"234-239"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of HOXA10 and HOXA11 in the endometrium of infertile patients with chronic endometritis. 慢性子宫内膜炎不孕患者子宫内膜中 HOXA10 和 HOXA11 的表达。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-05-23 DOI: 10.5935/1518-0557.20240035
Ana Carolina Mendonça Hissa de Sá, Luiz Felipe Bittencourt de Araujo, Mylena Zuim Sanson, Tamyres Souza Garcia Alvim Ranzato, Amanda Rezende Passarelli Tostes, Ivan Andrade de Araujo Penna
{"title":"Expression of HOXA10 and HOXA11 in the endometrium of infertile patients with chronic endometritis.","authors":"Ana Carolina Mendonça Hissa de Sá, Luiz Felipe Bittencourt de Araujo, Mylena Zuim Sanson, Tamyres Souza Garcia Alvim Ranzato, Amanda Rezende Passarelli Tostes, Ivan Andrade de Araujo Penna","doi":"10.5935/1518-0557.20240035","DOIUrl":"https://doi.org/10.5935/1518-0557.20240035","url":null,"abstract":"<p><strong>Objective: </strong>The study aimed to evaluate the impact of CE on the expression of HOXA10 and HOXA11 during the late proliferative phase in the endometrium of infertile women.</p><p><strong>Methods: </strong>A prospective, translational cohort study was conducted in partnership with the Hospital Universitário Antônio Pedro in Niterói and the Clínica Ginendo in Rio de Janeiro after approval by the Ethics Committee. The patients were selected to participate in the study after showing an indication for hysteroscopy. All participants were divided into three groups: infertile women with endometritis (n=10), infertile women without endometritis (n=17) and fertile women without endometritis (n=10). At hysteroscopy, two endometrial samples were obtaneid, with one sent for histopathological examination per the gynecologist's request and the other used for immunohistochemistry procedures to evaluate the expression of CD138, HOXA10 and HOXA11. CD138 was used to confirm the diagnosis of CE. The analysis of HOXA10 and HOXA11 was performed using the HScoring method for immunohistochemistry with polyclonal antibodies.</p><p><strong>Results: </strong>Women with and without endometritis had lower HOXA10 and HOXA11 expression values than women in the control group (fertile women without endometritis).</p><p><strong>Conclusions: </strong>The expression of HOXA10 and HOXA11 during the proliferative phase is not significantly different between infertile women with endometritis and infertile women without endometritis. Translational studies with a larger number of patients should be performed.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low ovarian responders produce more progesterone per follicle than normal and high responders. 与正常和高反应者相比,低卵巢反应者每个卵泡产生的孕酮更多。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-05-23 DOI: 10.5935/1518-0557.20240043
Alfredo Cortés-Vazquez, Alfredo Leonardo Cortés-Algara, Daniel Moreno-García, Johnny S Younis
{"title":"Low ovarian responders produce more progesterone per follicle than normal and high responders.","authors":"Alfredo Cortés-Vazquez, Alfredo Leonardo Cortés-Algara, Daniel Moreno-García, Johnny S Younis","doi":"10.5935/1518-0557.20240043","DOIUrl":"https://doi.org/10.5935/1518-0557.20240043","url":null,"abstract":"<p><strong>Objective: </strong>Late follicular premature progesterone rise is a complex phenomenon encountered during assisted reproductive technology (ART) treatments; different etiologies can occur in the same patient. Low ovarian responders may be the best example, since higher FSH doses and ovarian aging-related changes may interact and generate a premature progesterone rise. This study aims to explore the correlation between progesterone levels on hCG day and the progesterone-to-follicle index and compare the progesterone-to-follicle index according to ovarian response.</p><p><strong>Methods: </strong>We performed a retrospective, observational, analytic, cross-sectional, and cohort study at the Reproductive Endocrinology Department at Centro Médico Nacional 20 de November between January 2015 to January 2020. After verifying for normalcy, a Spearman Rho, Principal Component Analysis, and a simple linear regression model were performed. Treatment cycles were classified according to their ovarian response. Low-ovarian responders were classified according to the Bologna Criteria. Then an ANOVA test was performed to compare each group.</p><p><strong>Results: </strong>Our results show that the progesterone-to-follicle index correlates best with progesterone levels on hCG day. Comparing all the ovarian responses, low ovarian responders have the highest progesterone-to-follicle index of the four groups.</p><p><strong>Conclusions: </strong>Low ovarian responders produce more progesterone per follicle than regular and high responders.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of pre-treatment in GnRH-antagonist cycles triggered with GnRH agonist on reproductive outcomes. GnRH激动剂触发的GnRH拮抗剂周期中预处理对生殖结果的影响。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230022
Einat Zivi, Talia Eldar-Geva, Esther Rubinstein, Nava Dekel, Oshrat Schonberger, Ido Ben-Ami
{"title":"Impact of pre-treatment in GnRH-antagonist cycles triggered with GnRH agonist on reproductive outcomes.","authors":"Einat Zivi, Talia Eldar-Geva, Esther Rubinstein, Nava Dekel, Oshrat Schonberger, Ido Ben-Ami","doi":"10.5935/1518-0557.20230022","DOIUrl":"10.5935/1518-0557.20230022","url":null,"abstract":"<p><strong>Objective: </strong>Pre-treatment (PT) therapies in IVF are known to be used as pre-stimulation modality to improve cycle outcomes. This study aims to assess whether PT in GnRH antagonist cycles triggered with GnRH-agonist impact oocyte maturation response.</p><p><strong>Methods: </strong>Data were retrospectively collected for patients who underwent GnRH antagonist cycle with agonist triggering with and without PT. The patients were allocated to groups according to their PT status. The primary outcome evaluated was suboptimal maturation response. Suboptimal maturation to trigger was defined as no oocyte upon retrieval when adequate response was expected.</p><p><strong>Results: </strong>The study population included 196 patients who underwent GnRH antagonist cycle with agonist triggering. The study group included 69 patients who received PT. The control group included 127 patients with no PT. In univariate analysis, the PT group significantly displayed suboptimal response compared to the controls (p = 0.008). All the patients in the study group with suboptimal response (with or without hCG re-triggering) were treated with GnRH-agonist as PT. Basal and pre-trigger LH values were significantly lower in the study group compared to controls (p < 0.001). Multivariate regression analysis revealed that PT with GnRH agonist was a significant predictor for suboptimal response.</p><p><strong>Conclusions: </strong>Pre-treatment, and particularly the use of GnRH-agonist as PT in antagonist cycles triggered with agonist, increases the risk of suboptimal response to GnRH-agonist trigger. This might be explained by prolonged pituitary suppression, which lasts beyond the PT cessation.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"2-8"},"PeriodicalIF":1.5,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10936906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arjunolic acid reverses fluoxetine-induced alterations in testicular steroidogenic enzymes and membrane bound ionic pump imbalance through suppression of oxido-inflammatory stress and apoptosis. Arjunolic acid Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic Arjunolic通过抑制氧化炎症应激和细胞凋亡逆转氟西汀诱导的睾丸甾体生成酶和膜结合离子泵失衡的改变。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230062
Edozie Ojochem Lynda, Nwangwa Eze Kingsley, Oyovwi Mega Obukohwo, Ben-Azu Benneth, Emojevvwe Victor, Ovuakporaye I Simon, Ejime Agbonifo-Chijiokwu, Onome B Oghenetega
{"title":"Arjunolic acid reverses fluoxetine-induced alterations in testicular steroidogenic enzymes and membrane bound ionic pump imbalance through suppression of oxido-inflammatory stress and apoptosis.","authors":"Edozie Ojochem Lynda, Nwangwa Eze Kingsley, Oyovwi Mega Obukohwo, Ben-Azu Benneth, Emojevvwe Victor, Ovuakporaye I Simon, Ejime Agbonifo-Chijiokwu, Onome B Oghenetega","doi":"10.5935/1518-0557.20230062","DOIUrl":"10.5935/1518-0557.20230062","url":null,"abstract":"<p><strong>Objective: </strong>The impact of the anti-depressant therapy on gonadal function has been recognized and discussed over the years. However, data to supplement our understanding of the impact of arjunolic acid (AA) therapies in protecting against FXT-induced gonadal dysfunction is lacking clear scientific evidence. Hence, this study aimed to investigate the possible effect of AA on fluoxetine-induced altered testicular function in rats.</p><p><strong>Methods: </strong>After 14 days acclimatization, Thirty-six (36) adult male rats were randomly divided into 6 groups (n=6). Rats in groups 1 received normal saline (10mL/kg); groups 2 & 3 were given AA (1.0mg/kg body weight) and AA (2.0mg/kg body weight), respectively; whereas, rats in group 4 were given FXT (10mg/kg/p.o/day), and groups 5 & 6 were given a combination of FXT (10mg/kg) + AA (1.0mg/kg body weight); and FXT (10mg/kg) + AA (2.0mg/kg body weight), respectively.</p><p><strong>Results: </strong>The results shows that FXT significantly altered testicular steroidogenic enzymes (3ß-HSD and 17ß-HSD) and proton pump ATPase (Na+/K+ ATPase, Ca2+ ATPase and H+ ATPase) activities, as well as testicular architecture when compared with controls. More so, FXT caused oxido-inflammation and apoptosis, as evidence by increases in MDA, MPO, TNF-α, IL-1ß, Caspase 3 and p53. However, AA at a different dose significantly ameliorated the destructive impacts of FXT on steroidogenic enzymes, proton pump ATPase as well as increased Bcl-2, SOD, CAT, GSH and improved testicular architecture in rats.</p><p><strong>Conclusions: </strong>AA reverses fluoxetine-induced alterations in testicular steroidogenic enzymes and membrane-bound ionic pump through suppression of oxido-inflammatory stress and apoptosis.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"66-77"},"PeriodicalIF":1.5,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10936923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between hCG and GnRH Agonist for Ovulation Trigger in GnRH Antagonist In-Vitro Fertilization Cycles in a Tertiary Hospital in Malaysia: An observational study. 马来西亚一家三甲医院在GnRH拮抗剂体外受精周期中使用hCG和GnRH激动剂促排卵的比较:一项观察性研究。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230066
Nor Azimah Aziz, Adibah Ibrahim, Roziana Ramli, Nasuha Yaacob, Siti Nabillah Abdul Rahman, Engku Husna Engku Ismail, Ahmad Akram Omar
{"title":"Comparison between hCG and GnRH Agonist for Ovulation Trigger in GnRH Antagonist In-Vitro Fertilization Cycles in a Tertiary Hospital in Malaysia: An observational study.","authors":"Nor Azimah Aziz, Adibah Ibrahim, Roziana Ramli, Nasuha Yaacob, Siti Nabillah Abdul Rahman, Engku Husna Engku Ismail, Ahmad Akram Omar","doi":"10.5935/1518-0557.20230066","DOIUrl":"10.5935/1518-0557.20230066","url":null,"abstract":"<p><strong>Objective: </strong>hCG is commonly used as an ovulation trigger in IVF. Its usage is associated with OHSS. GnRH agonist is an alternative to hCG and is associated with reduced incidence of OHSS. This study compared the cycle outcomes of GnRH agonists with hCG as an ovulation trigger in IVF cycles.</p><p><strong>Methods: </strong>The medical notes of 209 IVF cycles receiving GnRH agonist and hCG as ovulation trigger over 18 months were reviewed in this retrospective study. The number and quality of mature oocytes, the number and quality of embryos, pregnancy rates, and outcomes were compared using Independent T-test or One-way ANOVA for normal distribution. The Mann-Whitney test or Kruskal-Wallis test was used for not normally distributed. p<0.05 was considered statistically significant.</p><p><strong>Results: </strong>The cycle outcomes of 107 GnRH agonist-trigger and 102 hCG-trigger were compared. The MII oocytes retrieved and 2PN count was significantly higher in the GnRH agonist trigger group (p<0.001). Clinical pregnancy rate and ongoing pregnancy were higher in the GnRH agonist trigger group but were not statistically significant. The GnRH agonist trigger group was associated with low OHSS than the hCG trigger group (n=2(1.9%) and n=12(11.8%) respectively, p=0.004).</p><p><strong>Conclusion: </strong>GnRH agonist trigger is an option as a final maturation trigger in high-responder women undergoing IVF or ICSI cycles.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"21-26"},"PeriodicalIF":1.5,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10936917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139472344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between Diameter of Yolk Sac on Transvaginal Ultrasonography at 6-12 Weeks of Gestation and Adverse Pregnancy Outcomes. 妊娠6-12周卵黄囊直径与不良妊娠结局的关系
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230052
Haitham Fathy Gad, Mohamed Mahmoud Salman, Magdy Hassan Koleib, Aya Ibrahim Nada, Mohamed Abdellatif Daoud
{"title":"Correlation between Diameter of Yolk Sac on Transvaginal Ultrasonography at 6-12 Weeks of Gestation and Adverse Pregnancy Outcomes.","authors":"Haitham Fathy Gad, Mohamed Mahmoud Salman, Magdy Hassan Koleib, Aya Ibrahim Nada, Mohamed Abdellatif Daoud","doi":"10.5935/1518-0557.20230052","DOIUrl":"10.5935/1518-0557.20230052","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the correlation between yolk sac diameter at 6 to 12 weeks of gestation measured via transvaginal ultrasound and adverse pregnancy outcomes.</p><p><strong>Methods: </strong>This prospective cohort study was conducted at the Ain Shams University Maternity Hospital from July 1, 2019 to January 30, 2020. It included 120 pregnant women attending the outpatient clinic at 6 to 12 weeks of gestation. Transvaginal ultrasound was performed to measure inner yolk sac diameter. Normal diameter was considered to be 2-5 mm. Cases were followed up in routine antenatal care until the 16th week of gestation.</p><p><strong>Results: </strong>Significant associations were found between maternal age and yolk sac diameter; yolk sac diameter and early miscarriage; a high percentage of cases of positive fetal life occurred when a normal yolk sac diameter (2-5 mm) was present (p<0.001); in yolk sac diameters <2mm positive fetal life was 0.0% and negative fetal life was 42.9%; in yolk sac diameters of 2-5mm positive fetal life was 81.1% and the negative fetal life was 7.1%; and in yolk sac diameters >5mm positive fetal life was 18.9% and negative fetal life was 50.0% (p<0.001), x2 60.094; and the best cutoff value for yolk sac diameter was >0.56, with a sensitivity of 78.6%, a specificity of 84.3%.</p><p><strong>Conclusions: </strong>We found a highly significant correlation between yolk sac diameter and early pregnancy loss.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"47-53"},"PeriodicalIF":1.5,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10936919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune system cells modulation in patients with reproductive issues: A systematic review approach. 生殖问题患者的免疫系统细胞调节:一项系统综述方法。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230044
Gabriel Acácio de Moura, Yasmim Mendes Rocha, Francisca Lariza Damascieira Moura, Janaína de Oliveira Freitas, João Pedro Viana Rodrigues, Vanessa Pinheiro Gonçalves, Roberto Nicolete
{"title":"Immune system cells modulation in patients with reproductive issues: A systematic review approach.","authors":"Gabriel Acácio de Moura, Yasmim Mendes Rocha, Francisca Lariza Damascieira Moura, Janaína de Oliveira Freitas, João Pedro Viana Rodrigues, Vanessa Pinheiro Gonçalves, Roberto Nicolete","doi":"10.5935/1518-0557.20230044","DOIUrl":"10.5935/1518-0557.20230044","url":null,"abstract":"<p><p>The aim of this study was to carry out a systematic literature review to investigate the main immune cells responsible for implantation failures. We selected papers from PubMed, Embase and Virtual Health Library databases. Eligible articles included publications between January 1, 2010 and April 24, 2022. Inclusion criteria were: observational and case-control studies; and the exclusion criteria were: review papers, letters to the editor, abstracts, animal studies and case reports. We extracted the following information: day of collection, number of patients, control group, age of patients, type of sample used, immune cells and cytokines. As main findings in our mapping, we found that in peripheral blood, CD3+, CD4+, CD8+, CD16+, CD56+, CD57+, CD69+, CD154+, CD158a+, NKp46 cells were increased and the CD4+, CD45+, Foxp3 and NKp46 markers were reduced. From the endometrial biopsies, there was an increase in CD3+, CD4+, CD5+, CD8+, CD16+, CD25+, CD45+, CD56+, CD57+, CD68+, CD127+ and a reduction in CD45+, CD56+, NKp46 and FoxP3 cells. Cytokines found increased in peripheral blood included IL-6, IL-10, IL-17, INF-γ, TGF-ß, TNF-α; while IL-4, IL-6, IL-10, IL-35, FoxP3, TGF-ß, SOCS3 were reduced. As for the biopsies, there was an increase in IL-2, IL-6, IL-17, IL-22, IL-23, INF-A1, INF-B1, INF-γ, TNF-R and a reduction in IL-6, IL-10, INF-γ, TGFß, TNF-α. We concluded that immune cells can be modulated during pregnancy failure, but further studies are needed to elucidate the modulating effect of the immune system on the endometrium of these patients.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"78-89"},"PeriodicalIF":1.5,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10936913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transient ovarian torsion in a pregnant woman after vitrified-warmed embryo transfer: a case report. 玻璃化加热胚胎移植后孕妇短暂性卵巢扭转1例报告。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230056
Hoda Sibai, Ahmed Ismail Heraiz, Nadia M Madkour
{"title":"Transient ovarian torsion in a pregnant woman after vitrified-warmed embryo transfer: a case report.","authors":"Hoda Sibai, Ahmed Ismail Heraiz, Nadia M Madkour","doi":"10.5935/1518-0557.20230056","DOIUrl":"10.5935/1518-0557.20230056","url":null,"abstract":"<p><p>Assisted reproduction is a risk factor for adnexal torsion due to ovarian hyperstimulation and increased incidence of twin pregnancy. Both risk factors can be eliminated in frozen embryo transfers, but in our case ovarian torsion occurred after the use of an aromatase inhibitor (Femara) in endometrium preparation due to the presence of corpus luteum. Case presentation: G2P1+0 presented at 7 weeks gestation after vitrified-warmed embryo transfer with right loin pain and mild right iliac pain and tenderness. Ultrasound examination revealed transient or incomplete ovarian torsion. The presentation of the case was somewhat misleading and the transient nature of the torsion provided an opportunity for the conservative management of the case. In conclusion, ovarian torsion is still an undesired event, even after single embryo transfers and in vitrified-warmed cycles. Clinical and ultrasound follow-up precluded the need for surgery in our case.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"209-210"},"PeriodicalIF":1.5,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10936916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ureterovaginal fistula: a case report and review of an unexpected contemporary complication secondary to transvaginal ultrasound-guided oocyte retrieval. 输尿管阴道瘘:经阴道超声引导取卵术后意外并发症的病例报告和回顾。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-02-26 DOI: 10.5935/1518-0557.20230063
Gabriel Chahade Sibanto Simões, Dalmo de Barros E Silva, Joao Roberto Paladino Júnior, Guilherme Lamacchia, Alexandre Gomes Sibanto Simões
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