Jornal Brasileiro de Reproducao Assistida最新文献

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RETRACTION NOTE TO: Effect of Intra Uterine Granulocyte Colony Stimulating Factor vs. Human Chorionic Gonadotropin at Ovum Pick-Up Day on Pregnancy Rate in IVF/ICSI Cases With Recurrent Implantation Failure. 撤稿说明:在取卵日使用宫内粒细胞集落刺激因子与人绒毛膜促性腺激素对反复着床失败的试管婴儿/卵胞浆内单精子显微注射病例妊娠率的影响。
IF 1.8
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-08-23 DOI: 10.5935/1518-0557.20240059
Haitham Torky, El-Sayed El-Desouky, Ashraf El-Baz, Rania Aly, Osama El-Taher, Atef Shata, Ahmed Hussein, Heba Marie, Osama Deif, Ahmed Eldemery, Ashraf Abo-Louz
{"title":"RETRACTION NOTE TO: Effect of Intra Uterine Granulocyte Colony Stimulating Factor vs. Human Chorionic Gonadotropin at Ovum Pick-Up Day on Pregnancy Rate in IVF/ICSI Cases With Recurrent Implantation Failure.","authors":"Haitham Torky, El-Sayed El-Desouky, Ashraf El-Baz, Rania Aly, Osama El-Taher, Atef Shata, Ahmed Hussein, Heba Marie, Osama Deif, Ahmed Eldemery, Ashraf Abo-Louz","doi":"10.5935/1518-0557.20240059","DOIUrl":"10.5935/1518-0557.20240059","url":null,"abstract":"<p><p>The Editorial Board has retracted this article. After publication, concerns were raised about this study's reported data. We reached out to the authors to request their raw data, but they could not provide. Therefore, the Editorial Board no longer has confidence in the results presented.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":"28 3","pages":"526"},"PeriodicalIF":1.8,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of ovarian reserve in women with thyroid autoimmunity. 评估甲状腺自身免疫妇女的卵巢储备功能。
IF 1.8
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-28 DOI: 10.5935/1518-0557.20240032
Adriana Leal Griz Notaro, Filipe Tenório Lira Neto, Giuliano Marchetti Bedoschi, Maria Jéssica da Silva, Mariana Corrêa Nunes, Catharina Cavalcanti Pessoa Monteiro, José Natal Figueiroa, Alex Sandro Rolland Souza
{"title":"Evaluation of ovarian reserve in women with thyroid autoimmunity.","authors":"Adriana Leal Griz Notaro, Filipe Tenório Lira Neto, Giuliano Marchetti Bedoschi, Maria Jéssica da Silva, Mariana Corrêa Nunes, Catharina Cavalcanti Pessoa Monteiro, José Natal Figueiroa, Alex Sandro Rolland Souza","doi":"10.5935/1518-0557.20240032","DOIUrl":"10.5935/1518-0557.20240032","url":null,"abstract":"<p><strong>Objective: </strong>To compare the ovarian reserve of women of reproductive age with and without thyroid autoimmunity (TAI).</p><p><strong>Methods: </strong>We performed a retrospective analysis of medical records from an assisted reproduction clinic from February 2017 to December 2021. Women aged between18 and 47 years with data on antithyroperoxidase and antithyroglobulin (anti-Tg) antibodies and assessment of ovarian reserve by anti-müllerian hormone (AMH) and antral follicle count (AFC) were included. Among the 188 participants included, 63 were diagnosed with TAI, and 125 had both antibodies negative. AMH and AFC were compared between groups. Subanalysis based on age, types of antibodies, and thyroid function markers were performed. In addition, bivariate analysis and regression models were used.</p><p><strong>Results: </strong>Overall, there was no difference in the median levels of AMH or AFC between the two groups. However, in the subgroup analysis by age, we observed a trend towards lower median levels of AMH in women over 39 years with TAI (0.9 ng/mL vs. 1.5 ng/mL, p=0.08). In a subanalysis according to antibodies, we found a significantly lower median AFC in the group with anti-Tg than in the group without this antibody (8.0 follicles vs. 11.5 follicles, p=0.036). We also found a significantly higher prevalence of anti-Tg in patients with low ovarian reserve compared to those with normal reserve (60.7% vs. 39.3%, p=0.038).</p><p><strong>Conclusions: </strong>The ovarian reserve of women with TAI appears to be insidiously compromised over the years, with a decreased ovarian reserve in women with anti-Tg.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"442-449"},"PeriodicalIF":1.8,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin D and follicular recruitment in the in vitro fertilization cycle. 维生素 D 与体外受精周期中的卵泡募集。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240005
Roberto de A Antunes, Brenda M L de Melo, Maria do Carmo B de Souza, Marcelo M de Souza, Gabriela P S Melo, Thamires F M Jandre, Ana Cristina A Mancebo, Flavia L Conceição, Tania M Ortiga-Carvalho
{"title":"Vitamin D and follicular recruitment in the in vitro fertilization cycle.","authors":"Roberto de A Antunes, Brenda M L de Melo, Maria do Carmo B de Souza, Marcelo M de Souza, Gabriela P S Melo, Thamires F M Jandre, Ana Cristina A Mancebo, Flavia L Conceição, Tania M Ortiga-Carvalho","doi":"10.5935/1518-0557.20240005","DOIUrl":"10.5935/1518-0557.20240005","url":null,"abstract":"<p><strong>Objective: </strong>Vitamin D (VD) is a fat-soluble steroid hormone, synthesized by the skin, most known for its role in bone mineral balance. Vitamin D receptors (VDR) are also found in the female reproductive system, but their role remains unclear. The objective of this study was to analyze the relationship between serum vitamin D levels and the number of oocytes retrieved after ovarian stimulation.</p><p><strong>Methods: </strong>This is a retrospective study involving 267 patients undergoing in vitro fertilization (IVF) carried out in the Fertipraxis clinic, a private practice facility. The patients were initially divided into two groups according to their VD levels. Group 1 included 152 patients with VD levels < 30 ng/mL and group 2 had 115 patients with VD levels > 30 ng/mL. They were further analyzed and separated considering their age, anthropometric data, ovarian reserve, amount of gonadotropin used, and follicles obtained until trigger day.</p><p><strong>Results: </strong>In our analysis, there were no difference in the number of follicles and oocytes retrieved, nor in the number of mature oocytes obtained from patients with both vitamin D deficiency and sufficiency.</p><p><strong>Conclusions: </strong>The results of our study show no difference among number of follicles, oocytes retrieved and mature oocytes obtained after ovarian stimulation according to their vitamin D serum levels. Further higher-quality studies are needed to evaluate the possible roles of serum vitamin D levels in other stages of human fertilization process.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"269-275"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empty follicle syndrome following GnRH agonist stimulation, in a patient with PCOS treated with HCG rescue protocol, resulting in 3PN zygote formation: a case report. 一名接受 HCG 挽救方案治疗的多囊卵巢综合征患者在接受 GnRH 激动剂刺激后出现空卵泡综合征,导致 3PN 子体形成:病例报告。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20230051
Nasrin Saharkhiz, Nazanin Hajizade, Mahsa Kazemi, Samaneh Esmaeili, Bahareh Karimi
{"title":"Empty follicle syndrome following GnRH agonist stimulation, in a patient with PCOS treated with HCG rescue protocol, resulting in 3PN zygote formation: a case report.","authors":"Nasrin Saharkhiz, Nazanin Hajizade, Mahsa Kazemi, Samaneh Esmaeili, Bahareh Karimi","doi":"10.5935/1518-0557.20230051","DOIUrl":"10.5935/1518-0557.20230051","url":null,"abstract":"<p><p>Empty follicle syndrome is a rare condition characterized by failure to retrieve oocytes despite repeated careful aspiration of mature precursor follicles during controlled ovarian stimulation. This report presents a case of empty follicle syndrome in a patient with polycystic ovary syndrome using a gonadotropin-releasing hormone agonist as a trigger for final oocyte maturation. No oocytes were retrieved from the right ovary and the procedure was discontinued. The patient was administered an injection with 10,000 units of HCG and 3 oocytes were obtained after 24 hours. All oocytes were mature (MII); fertilization was performed with sperm from the patient's husband resulting in 3PN zygotes. The formation of 3PN zygotes from ICSI might be due to oocyte cytoplasmic disorders caused by long-term exposure to gonadotropins and increased duration of stimulation. Although our patient had false empty follicle syndrome and the hCG rescue protocol led to the retrieval of oocytes, the oocytes were not of good quality. As previously described, empty follicle syndrome is not a predictor of success in subsequent cycles. Our patient's next cycle was uneventful.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"365-367"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139472355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corpus luteum and progesterones in embryo transfer cycles: current challenges of different luteal phase support protocols. 胚胎移植周期中的黄体和孕酮:不同黄体期支持方案目前面临的挑战。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240044
Maria do Carmo Borges de Souza, Roberto de Azevedo Antunes, Marcelo Marinho de Souza, Hitomi Miura Nakagawa, Adelino Amaral Silva, Emerson Barchi Cordts, Caio Parente Barbosa
{"title":"Corpus luteum and progesterones in embryo transfer cycles: current challenges of different luteal phase support protocols.","authors":"Maria do Carmo Borges de Souza, Roberto de Azevedo Antunes, Marcelo Marinho de Souza, Hitomi Miura Nakagawa, Adelino Amaral Silva, Emerson Barchi Cordts, Caio Parente Barbosa","doi":"10.5935/1518-0557.20240044","DOIUrl":"10.5935/1518-0557.20240044","url":null,"abstract":"","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":"28 2","pages":"211-214"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probiotics supplementation in the treatment of male infertility: A Systematic Review. 补充益生菌治疗男性不育症:系统综述。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240013
Licia Cristina Silva de Lima Oliveira, Elton Carvalho Costa, Fernanda Domingues Gomes Martins, Alcenir Sales da Rocha, Girlandia Alexandre Brasil
{"title":"Probiotics supplementation in the treatment of male infertility: A Systematic Review.","authors":"Licia Cristina Silva de Lima Oliveira, Elton Carvalho Costa, Fernanda Domingues Gomes Martins, Alcenir Sales da Rocha, Girlandia Alexandre Brasil","doi":"10.5935/1518-0557.20240013","DOIUrl":"10.5935/1518-0557.20240013","url":null,"abstract":"<p><p>Infertility is a widespread global issue that affects approximately 15% of sexually active and active couples, which contributes to about 50% of cases. Currently, the condition remains prevalent and often inadequately treated. This systematic review aims to evaluate existing studies investigating the effects of probiotic supplementation in men. A comprehensive search was conducted across major databases, including PubMed, Cochrane, Science Direct, and Scielo, using relevant keywords such as 'probiotic' OR 'Lactobacillus' OR 'Bifidobacterium' AND 'Male infertility' OR 'male fertility' OR 'sperm quality' OR 'sperm motility' OR 'oligoasthenoteratozoospermia' and their Portuguese equivalents. Four randomized clinical studies met the inclusion criteria, focusing on men diagnosed with idiopathic male infertility (oligozoospermia, teratozoospermia, and asthenozoospermia). The findings revealed that probiotic administration exhibited promising antioxidant properties by combating reactive oxygen species (ROS), consequently protecting sperm DNA from damage that correlates with declining sperm quality. Significant improvements were observed across all sperm parameters, with notable enhancement in motility. Consequently, probiotic supplementation emerges as a potential therapeutic alternative for men diagnosed with idiopathic infertility, demonstrating positive effects on sperm quality.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"341-348"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High ovarian responders have the highest risk of premature progesterone rise. 卵巢反应性高的人孕酮过早升高的风险最高。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240004
Alfredo Cortés-Vazquez, Greys Thelma Vásquez-Ramírez, Alfredo Leonardo Cortés-Algara, Jesús-Daniel Moreno-García, Panagiotis Drakopoulos
{"title":"High ovarian responders have the highest risk of premature progesterone rise.","authors":"Alfredo Cortés-Vazquez, Greys Thelma Vásquez-Ramírez, Alfredo Leonardo Cortés-Algara, Jesús-Daniel Moreno-García, Panagiotis Drakopoulos","doi":"10.5935/1518-0557.20240004","DOIUrl":"10.5935/1518-0557.20240004","url":null,"abstract":"<p><strong>Objective: </strong>Late follicular phase progesterone elevation is a complication that affects approximately 38% of IVF cycles. There is a lack of consensus on the appropriate cut-off levels for progesterone on hCG day. Although premature progesterone rise occurs in all kinds of ovarian responses, there is a knowledge gap regarding the ovarian response with the highest risk of this phenomenon. Our study aims to assess the relative risk of each kind of ovarian response for premature progesterone rise and evaluate the prevalence of premature progesterone rise in each ovarian response.</p><p><strong>Methods: </strong>A retrospective, cross-sectional, comparative and analytic study was performed at the Reproductive Endocrinology Department in Centro Médico Nacional 20 de Noviembre in Mexico City. All conventional-antagonist cycles were grouped according to their ovarian response and were evaluated from 2015 to 2020. Pearson's Squared-chi, Cramer's V, cross-table and the relative risk were calculated.</p><p><strong>Results: </strong>The prevalence of premature progesterone rise oscillated from 20.8 to 67.9% for low and high ovarian responders, respectively. After calculating the relative risk, high ovarian responders had a 1.38 higher risk for premature progesterone rise than other groups.</p><p><strong>Conclusions: </strong>High ovarian responders have the highest risk for premature progesterone rise compared to normal and low ovarian responders. High ovarian responders have a 67.9% prevalence of premature progesterone rise.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"295-298"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of coenzyme Q10 on cryotolerance of in vivo-derived mouse embryos. 辅酶Q10对体内衍生小鼠胚胎低温耐受性的影响
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240029
Parichehr Sadat Hosseini, Iraj Jafari Anarkooli, Alireza Abdanipour, Mitra Arianmanesh
{"title":"The effect of coenzyme Q10 on cryotolerance of in vivo-derived mouse embryos.","authors":"Parichehr Sadat Hosseini, Iraj Jafari Anarkooli, Alireza Abdanipour, Mitra Arianmanesh","doi":"10.5935/1518-0557.20240029","DOIUrl":"10.5935/1518-0557.20240029","url":null,"abstract":"<p><strong>Objective: </strong>Cryopreservation has some adverse effects on embryos including cell metabolism reduction, mitochondria and plasma membrane damage, excess production of 'Reactive Oxygen Species' and damage to DNA. In the present study. In this study we assessed the effect of coenzyme Q10 as an exogenous antioxidant on mouse embryos following cryopreservation.</p><p><strong>Methods: </strong>We collected mice embryos at the morula stage from uterine horns on the third day of gestation. The morulae were divided into 9 groups (1 control, 2 vehicles and 6 experimental), then vitrified. The culture and/or vitrification media of the experimental groups were supplemented by 10 or 30 μM of CoQ10. After one week, the embryos were warmed and then cultured. After 48 hours of embryo culture, the blastocyst rate, total cell number, viability; and after 72 hours of embryo culture, we assessed the hatching rate.</p><p><strong>Results: </strong>Blastocyst rate and hatching rate were significantly reduced in the groups containing 30 μM CoQ10 supplemented culture media compared to other groups (p<0.05). The hatching rate in the groups containing 10 μM CoQ10 supplemented in both culture and vitrification media was significantly higher than in the other groups (p<0.05). In groups containing 10 μM CoQ10 supplemented culture media, the viability was higher than that in the other groups (p<0.05).</p><p><strong>Conclusions: </strong>It seems that CoQ10 in a dose-dependent manner is able to improve hatching rate and viability following cryopreservation through its antioxidant and anti-apoptotic properties, and through the production of ATP.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":"28 2","pages":"276-283"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety of Plasma Rich in Growth Factors (PRGF) as additive to healthy human sperm samples: a pilot study. 富含生长因子的血浆(PRGF)作为健康人类精子样本添加剂的安全性:一项试点研究。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20230075
Fernando Quintana, Alberto Vendrell, Silvia Perez- Fernandez, Maria de la Fuente, Aitana Merino-Pérez, Marcos Ferrando, Roberto Matorras
{"title":"Safety of Plasma Rich in Growth Factors (PRGF) as additive to healthy human sperm samples: a pilot study.","authors":"Fernando Quintana, Alberto Vendrell, Silvia Perez- Fernandez, Maria de la Fuente, Aitana Merino-Pérez, Marcos Ferrando, Roberto Matorras","doi":"10.5935/1518-0557.20230075","DOIUrl":"10.5935/1518-0557.20230075","url":null,"abstract":"<p><strong>Objective: </strong>The aim of our study was to assess if the addition of PRGF to healthy human sperm affects its motility and vitality.</p><p><strong>Methods: </strong>This was a prospective study, with 44 sperm donors on whom sperm analysis was performed. Nine mL of blood was collected and PRGF was obtained using PRGF-Endoret® technology. The influence of different dilutions of PRGF (5%, 10%, 20%, 40%) applied to 15 sperm donors was compared, and sperm motility was assessed after 30 minutes. In the second part of the study, 29 sperm donors were studied to analyze the influence of 20% dilution of PRGF at 15, 30 and 45 minutes in fresh and thawed sperm samples. Motility was assessed after the addition of PRGF and after analysis each aliquot was frozen. After thawing, concentration and motility were assessed at the same time periods.</p><p><strong>Results: </strong>There were no differences in sperm motility in fresh samples between dilutions of PRGF when assessed 30 minutes after administration, nor between them, nor when compared to the control group immediately prior to treatment. No trend was observed between motility and PRGF dilution in linear regression analysis. There were no significant differences in thawed samples.</p><p><strong>Conclusions: </strong>The administration of 20% PRGF dilution had no effect on sperm motility compared to samples without PRGF. In addition, there was no change in sperm vitality when comparing samples with and without PRGF. More studies focusing on subnormal sperm samples, analyzing different PRGF concentrations and increasing the number of study variables are needed.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"224-233"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of major analgesics on male fertility: A systematic literature review. 主要镇痛药对男性生育能力的影响:系统文献综述。
IF 1.5
Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-06-01 DOI: 10.5935/1518-0557.20240020
Melissa Figueiredo Capelo, Paula Bruno Monteiro, Beatriz Matos Anastácio
{"title":"Effects of major analgesics on male fertility: A systematic literature review.","authors":"Melissa Figueiredo Capelo, Paula Bruno Monteiro, Beatriz Matos Anastácio","doi":"10.5935/1518-0557.20240020","DOIUrl":"10.5935/1518-0557.20240020","url":null,"abstract":"<p><strong>Objective: </strong>To verify, based on a systematic literature review, the effects of the main analgesics on male fertility.</p><p><strong>Data sources: </strong>The studies were analyzed from the PubMed, SciELO and LILACS databases.</p><p><strong>Study selection: </strong>The articles selected for the present review included: cohort studies; cross-sectional studies, clinical trials; complete studies; studies with animal models that addressed the proposed theme and that were published within the stipulated period from March 1, 2013, to March 31, 2023, in English, Portuguese and Spanish. These would later have to go through inclusion stages such as framing the type of study and exclusion criteria.</p><p><strong>Data collection: </strong>Author's name, year of publication, study population, number of patients, analgesic, administration time, dose, and effect.</p><p><strong>Conclusions: </strong>There are in vitro and in vivo studies that link paracetamol and ibuprofen to endocrine and seminal changes that are harmful to male fertility. However, more clinical research is needed to determine the doses and timing of administration that affect fertility. The effects of aspirin on male fertility are still unclear due to the lack of studies and consistent methodologies. There is not enough research on dipyrone and its relationship with male fertility, requiring more studies in this area.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"331-340"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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