The correlation between abnormal Krüger strict morphology and the sperm DNA fragmentation index.

IF 1.8 Q3 OBSTETRICS & GYNECOLOGY

Jornal Brasileiro de Reproducao Assistida Pub Date : 2024-12-02 DOI:10.5935/1518-0557.20240068

Tamyres Souza Garcia Alvim Ranzato, Mariana Duque de Mello, Paula Fontoura Coelho de Souza, Lincoln Bastos Farias, Luiz Felipe Bittencourt de Araujo, Ivan Andrade de Araujo Penna

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引用次数: 0

Abstract

Objective: This study aims to investigate whether alterations in sperm DNA fragmentation rates are more frequent when Krüger strict morphology is ≥4% (normal).

Methods: The retrospective study included 132 participants from March 2020 to November 2021. Participants were divided into two groups based on the inclusion criteria: normal and abnormal Krüger strict morphology, with a mean age of 40 years. Seminal analyses were conducted following the guidelines outlined in the 6th edition of the Manual for Examination and Processing of Human Semen (2021). The sperm chromatin dispersion test was used.

Results: The results did not reveal a statistically significant difference between Krüger strict morphology and Sperm DNA Fragmentation Index correlation (p<0.05) between the normal and abnormal morphology groups (p<0.05) and in Seminal Parameters. Sperm concentration is lower when Krüger strict morphology is < 4% (abnormal) (p=0.007).

Conclusions: In conclusion, abnormal Krüger strict morphology does not have a higher predisposition to increased sperm DNA fragmentation.

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kr ger严格形态异常与精子DNA断裂指数的关系。

目的：本研究旨在探讨当kr格严格形态≥4%（正常）时，精子DNA断裂率的改变是否更为频繁。方法：回顾性研究纳入132名参与者，时间为2020年3月至2021年11月。根据kr格严格形态学正常和异常分为两组，平均年龄40岁。根据《人类精液检验和处理手册》（2021年）第6版中概述的指导方针进行了精液分析。采用精子染色质分散试验。结果：kr格严格形态与精子DNA片段化指数相关性无统计学差异(p)。结论：结论：kr格严格形态异常与精子DNA片段化增加没有较高的易感性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Jornal Brasileiro de Reproducao Assistida OBSTETRICS & GYNECOLOGY-

CiteScore

3.30

自引率

6.70%

发文量