Jornal Brasileiro de Reproducao Assistida最新文献_第2页

Protective Effects of Adipose Mesenchymal Stem Cell Secretome On Oxidative Stress-Induced Bisphenol-A in Isolated Rat Testes Mitochondria and Sperm Quality. 脂肪间充质干细胞分泌组对氧化应激诱导的大鼠睾丸双酚a、线粒体和精子质量的保护作用

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240089

Maryam Zohour Soleimani, Layasadat Khorsandi, Yousef Asadi-Fard, Fatemeh Rezaei-Tazangi, Atefeh Ashtari

{"title":"Protective Effects of Adipose Mesenchymal Stem Cell Secretome On Oxidative Stress-Induced Bisphenol-A in Isolated Rat Testes Mitochondria and Sperm Quality.","authors":"Maryam Zohour Soleimani, Layasadat Khorsandi, Yousef Asadi-Fard, Fatemeh Rezaei-Tazangi, Atefeh Ashtari","doi":"10.5935/1518-0557.20240089","DOIUrl":"10.5935/1518-0557.20240089","url":null,"abstract":"Objective: This study aimed to explore the potential protective effects of adipose-derived mesenchymal stem cell secretome (ASE) on oxidative stress triggered by Bisphenol-A (BisA) exposure in testicular mitochondria and sperm quality of rats.Methods: Testicular tissue mitochondria and sperms were exposed to BisA (8 μM) and ASE (50 or 100 μg). ∆Ψm (mitochondrial membrane potential), reactive oxygen species (ROS) levels, antioxidant biomarkers, and sperm parameters were measured.Results: BisA elevated biomarkers of oxidative stress in mitochondria, while the levels of antioxidant activity and ∆Ψm decreased significantly. BisA harmed the morphology, survival rate, and mobility of the spermatozoids. ASE lowered malondialdehyde contents and ROS generation in the mitochondria, increased ∆Ψm, and reversed sperm quality.Conclusions: These data indicated that ASE effectively reduced BisA-induced damage to mitochondria and enhanced sperm quality by averting oxidative stress.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"53-60"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Swyer Syndrome: A diagnostic challenge. 斯威耶综合征：一个诊断挑战。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240096

Imen Bannour, Badra Bannour, Salma Ferjani, Sassi Boughizane

{"title":"Swyer Syndrome: A diagnostic challenge.","authors":"Imen Bannour, Badra Bannour, Salma Ferjani, Sassi Boughizane","doi":"10.5935/1518-0557.20240096","DOIUrl":"10.5935/1518-0557.20240096","url":null,"abstract":"Swyer syndrome, represents a rare manifestation of primary amenorrhea arising from gonadal dysgenesis. This syndrome is distinguished by the manifestation of a female phenotype despite a 46, XY karyotype. We present the case of a patient aged 32 the second of three sisters; consulted for the first time with a main complaint of primary unexplored amenorrhea responsible for infertility of 1 year with a female phenotype and a male karyotype: 46XY. The laparoscopy performed revealed the presence of a small uterus (an unexpected finding for a feminizing testicular syndrome). The other sisters were respectively examined and found to have the same pathology as their sister and were eventually programmed to have a laparoscopy. 46XY pure gonadal dysgenesis, commonly known as Swyer syndrome, presents as a rare disorder in sexual development. Despite having a 46XY karyotype, affected individuals exhibit a female phenotype. The underlying cause is believed to stem from mutations and deletions affecting the Sex Determining Region Y (SRY) gene located on the short arm of the Y chromosome. Swyer syndrome should be considered in cases of primary amenorrhea with the presence of a uterus. Chromosomal analysis is essential for confirming the diagnosis.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":"29 1","pages":"195-198"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of a woman's own eggs in her first IVF treatment at the age of 48 years and 10 months with successful live birth after PGT-A: a case report. 一位妇女在 48 岁零 10 个月时使用自己的卵子进行首次试管婴儿治疗，并在 PGT-A 后成功产下活婴：病例报告。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240072

Claudia Gomes, Mariana Nicolielo Barreto, Anaíde Silva Sousa, Dayane Guerino Reis, Priscila Beirigo, Izadora Reis, Caroline Fauth, Andrea Belo, Hanna Park, Ana Luiza Tavares, Livia Munhoz, José Roberto Alegretti, Dóris S Chéles, Aline R Lorenzon

{"title":"The use of a woman's own eggs in her first IVF treatment at the age of 48 years and 10 months with successful live birth after PGT-A: a case report.","authors":"Claudia Gomes, Mariana Nicolielo Barreto, Anaíde Silva Sousa, Dayane Guerino Reis, Priscila Beirigo, Izadora Reis, Caroline Fauth, Andrea Belo, Hanna Park, Ana Luiza Tavares, Livia Munhoz, José Roberto Alegretti, Dóris S Chéles, Aline R Lorenzon","doi":"10.5935/1518-0557.20240072","DOIUrl":"10.5935/1518-0557.20240072","url":null,"abstract":"Natural conception in women after the age of 45 years is rare. The probability of successful pregnancy in this specific group of women after IVF and embryo transfer with autologous oocytes is also reduced. In addition, advanced maternal age is associated with an increased risk of aneuploidies and other associated complications during pregnancy. Generally, women who are over 44 years old are advised to receive IVF treatment with donated oocytes due to poor oocyte quality and low ovarian reserve. Although IVF outcomes in women of advanced age can be associated with the best prognosis when donated oocytes are used, IVF is not always well accepted by infertile couples. This is a case report of a woman who achieved a clinical pregnancy and live birth in her first attempt at IVF treatment with her own eggs and a euploid embryo at 48 years and 10 months, respectively, at the time of oocyte retrieval. This case demonstrates that limited attempts at assisted reproductive technology with older women's own eggs may be an option in specific cases.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"191-194"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly purified-hMG versus rFSH in ovarian hyperstimulation in women undergoing elective fertility preservation: a retrospective cohort study. 选择性保留生育能力的妇女卵巢过度刺激中高纯度hmg与rFSH的对比：一项回顾性队列研究。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240099

Tal Israeli, Nivin Samara, Shimi Barda, Asnat Groutz, Foad Azem, Hadar Amir

{"title":"Highly purified-hMG versus rFSH in ovarian hyperstimulation in women undergoing elective fertility preservation: a retrospective cohort study.","authors":"Tal Israeli, Nivin Samara, Shimi Barda, Asnat Groutz, Foad Azem, Hadar Amir","doi":"10.5935/1518-0557.20240099","DOIUrl":"10.5935/1518-0557.20240099","url":null,"abstract":"Objective: To compare recombinant FSH (rFSH) with highly purified-human menopausal gonadotrophin (hp-hMG) on ovarian response in women undergoing elective fertility preservation (FP).Methods: This retrospective study included 456 women who underwent elective FP with gonadotropin-releasing hormone (GnRH) antagonist or progestin-primed ovarian stimulation (PPOS) protocols between 01/2017-12/2021. Only the first treatment cycle of each woman was included. 341 women were stimulated with rFSH and 115 with hp-hMG, and the ovarian stimulation outcomes were compared. A multivariate linear regression assessed the impact of age, basal FSH, antral follicle count (AFC) and protocol and gonadotropin types on the outcomes.Results: Women in the rFSH group were significantly younger, and their AFC was significantly higher than those in the hp-hMG group (35.50±2.12 vs. 35.99±2.13years, p=0.034 and 13.76±6.08 vs. 11.84±6.06, p=0.002). There were no significant group differences in the amount (p=0.645) and duration (p=0.265) of FSH stimulation. The estradiol level was significantly lower for the rFSH group compared to the hp-hMG group (2547.18±1648.21pg/mL vs. 3468.02±2497.69pg/mL, p<0.001), while the progesterone level was significantly higher (1.33±0.75 ng/mL vs. 1.01±0.52ng/mL, p=0.001). The numbers of retrieved and MII oocytes were significantly higher for the rFSH group compared with the hp-hMG group (16.82±10.95 vs. 13.25±9.66, p=0.02, and 13.22±9.13 vs. 9.76±7.11, p=0.005), while the maturity rates were comparable (p=0.103).Conclusions: Patients in the rFSH group had higher numbers of both retrieved and MII oocytes when undergoing elective FP.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"136-144"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to "Two livebirths achieved in cases of hypergonadotropic hypogonadism nonobstructive azoospermia, treated with GnRH agonist and gonadotrophins: a case series and review of the literature" [JBRA Assist Reprod. 2024;28(3):521-525]. “使用GnRH激动剂和促性腺激素治疗高促性腺功能低下非阻塞性无精子症的两例活产：病例系列和文献回顾”的更正[JBRA Assist rebd . 2024;28(3):521-525]。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20250001

Mauro Bibancos de Rose, Arhon Bizelli Sicard, Natalia Alvarenga Aguiar, Beatriz de Oliveira Onório, Antonio Alberto Rodrigues Almendra, Wagner Eduardo Matheus, Andrea Garolla, Carlo Foresta, Daniela Paes de Almeida Ferreira Braga, Amanda Souza Setti, Edson Borges

引用次数: 0

Effects of dietary quercetin on retrieved mouse oocytes and in vitro fertilization outcomes. 膳食槲皮素对小鼠卵母细胞提取和体外受精结果的影响

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240073

Rasrawee Chantrasiri, Pannarai Somboonchai, Waraporn Piromlertamorn, Tawiwan Pantasri, Usanee Sanmee

{"title":"Effects of dietary quercetin on retrieved mouse oocytes and in vitro fertilization outcomes.","authors":"Rasrawee Chantrasiri, Pannarai Somboonchai, Waraporn Piromlertamorn, Tawiwan Pantasri, Usanee Sanmee","doi":"10.5935/1518-0557.20240073","DOIUrl":"10.5935/1518-0557.20240073","url":null,"abstract":"Objective: To investigate the effects of dietary quercetin on the retrieved mouse oocytes and IVF outcomes.Methods: Female mice were divided into two groups. Mice were given 0.2 mL water without (control group) or with quercetin 30 mg/kg (quercetin group) orally via gavage, once a day for 21 consecutive days. After that female mice were superovulated for in vitro fertilization. We observed the effect of dietary quercetin on the number of retrieved oocytes, oocyte degeneration rate, fertilization rate, blastocyst formation rate, and blastocyst cell numbers.Results: There was no difference in the number of retrieved oocytes per mouse (27.3±6.7 and 27.2±5.8), oocyte fragmentation rate (28.4% and 25.0%), fertilization rate (47.4% and 50.6%) and blastocyst formation rate (34.8% and 34.7%) in the quercetin group compared to the control group. The proportion of hatching and hatched blastocyst was significantly lower in the quercetin group (17.2% and 27.8%, p=0.004) and significantly lower numbers of cells in TE (47.4±15.3 and 57.2±17.7) and total cells (66.2±18.5 and 77.5±20.7) compared to the control group (p=0.001).Conclusions: Dietary quercetin supplementation has a detrimental effect on mouse embryo quality. Moreover, it did not show any beneficial effect on the ovary in both quantity and quality. This finding raises awareness of the general use of dietary quercetin supplements in infertile females.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"16-20"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of information on fertility clinic websites accredited by the Latin American Network of Assisted Reproduction. 拉丁美洲辅助生殖网络认可的生育诊所网站的信息质量。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240074

Giselle Ferreira de Souza, Eduarda Maia Lima, Ana Clara Muniz Tavares, Camila Alves Rocha, Larissa Cruz de Souza, Júlia Machado Luz Simões, Nicole Oliveira de Araújo, Maria Yzadora Moura Martins, Marcelo Borges Cavalcante

{"title":"Quality of information on fertility clinic websites accredited by the Latin American Network of Assisted Reproduction.","authors":"Giselle Ferreira de Souza, Eduarda Maia Lima, Ana Clara Muniz Tavares, Camila Alves Rocha, Larissa Cruz de Souza, Júlia Machado Luz Simões, Nicole Oliveira de Araújo, Maria Yzadora Moura Martins, Marcelo Borges Cavalcante","doi":"10.5935/1518-0557.20240074","DOIUrl":"10.5935/1518-0557.20240074","url":null,"abstract":"Objective: To access to reproductive health information on the Internet helps patients understand their infertility journey and make decisions about their treatment. This study aimed to evaluate the quality of fertility clinic websites accredited by the Latin American Network for Assisted Reproduction (REDLARA) using the QUality Evaluation Scoring Tool (QUEST).Methods: This observational, cross-sectional, and online study evaluated the clinic websites registered as accredited centers on the REDLARA website. The QUEST was used for the quality assessment of the websites. Data were collected from the available websites of all accredited fertility clinics between September 2023 and January 2024.Results: A total of 173 websites from fertility clinics accredited by REDLARA were evaluated, and 152 (87.8%) clinics had functioning websites. The majority of analyzed websites were from Brazilian fertility clinics (n=58; 38.1%), followed by Mexican (n=23; 15.1%) and Argentine (n=21; 13.8%). No indication of authorship or username was observed on most websites. Some form of support for the patient-physician relationship was reported by 86.8% of websites. The mean (standard deviation±SD) of the total score obtained by all fertility clinics was 12.73±4.7 (range: 1-26). Brazil had the highest total score (mean±SD=16.03±4.6), whereas Peru had the lowest (6.42±1.7). Statistical analysis revealed a difference in the quality of websites among Latin American countries.Conclusions: The health information disseminated by fertility clinic websites in Latin America is of poor quality. Therefore, REDLARA should implement rules for building good-quality websites.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"27-34"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do LGTB people desire to have children? A Brazilian cross-sectional survey. lgbt人群想要孩子吗？巴西横断面调查。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240094

Rejane Casare, Kadija Chrisostomo, Najila Sandrin, Henrique Chrisostomo, Renato Nisihara

{"title":"Do LGTB people desire to have children? A Brazilian cross-sectional survey.","authors":"Rejane Casare, Kadija Chrisostomo, Najila Sandrin, Henrique Chrisostomo, Renato Nisihara","doi":"10.5935/1518-0557.20240094","DOIUrl":"10.5935/1518-0557.20240094","url":null,"abstract":"Objective: To identify whether the LGBT community desires to start a family and the major challenges they experience, especially in regards to assisted reproductive technology (ART) procedures in Brazil.Methods: This cross-sectional study invited individuals Brazilian, identified themselves as cisgender, and homosexual (male and female); aged 18-60, the study used an online questionnaire distributed through various platforms.Results: Of the 698 respondents, mostly educated and Caucasian, 86.7% were female. While 69% expressed same-sex orientation, many were in long-term relationships. Family acceptance varied, with financial barriers (69.3%) and societal prejudices (73.1%) being significant concerns. Despite a desire for children (92% were childless), only 10% consulted infertility specialists, and 66.5% were unaware of ART legislation. Emotionally, 51.1% felt unprepared for parenthood. While societal acceptance of non-heteronormative families is perceived to be increasing (53%), unequal healthcare treatment (73.1%) and societal pressures (20% felt pressured towards adoption) remain prevalent.Conclusions: Over 90% of LGBT individuals contemplate having biological or adoptive children. There's notable ignorance about legislation and ART. Financial hurdles in ART are significant but manageable with proper planning. Prejudice also strongly influences their lives.","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":"87-93"},"PeriodicalIF":1.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143013733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The endometrioma paradox.

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240090

João Antonio Dias, Carlos Roberto Izzo, Georges Fassolas, Luiz Fernando de Oliveira Henrique, Gustavo Arantes Rosa Maciel, Sérgio Podgaec, Luciana Carvalho Delamuta

引用次数: 0

Increased antinuclear (anti-Sm) antibodies in infertile patients with peritoneal endometriosis. 患有腹膜子宫内膜异位症的不孕患者体内抗核（抗Sm）抗体增加。

IF 1.8

Jornal Brasileiro de Reproducao Assistida Pub Date : 2025-03-12 DOI: 10.5935/1518-0557.20240070

Renata Fogaça Borges, Vanessa Krebs Genro, Carlos Augusto Bastos de Souza, Tatiana Ferreira Michelon, Isabel Meneghetti Coimbra, João Sabino Lahorgue da Cunha-Filho

引用次数: 0