Journal of Acute Disease最新文献

Epidemiological characteristics and trends of animal bites in Neyshabur, Iran: A cross-sectional study 伊朗内沙布尔动物咬伤的流行病学特征和趋势：横断面研究

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390387

Mansoore Sarcheshme Shariat, Nayereh Esmaeilzadeh, Nasibeh Zerangian, Nooshin Peyman

引用次数: 0

Predictors of hemorrhagic manifestations in dengue: A prospective observational study from the Hadoti region of Rajasthan 登革热出血性表现的预测因素：拉贾斯坦邦哈多蒂地区的前瞻性观察研究

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390384

S. Jelia, Devendra Ajmera, Divya Airan, Ranjeet Bairwa, Yogesh Meena

{"title":"Predictors of hemorrhagic manifestations in dengue: A prospective observational study from the Hadoti region of Rajasthan","authors":"S. Jelia, Devendra Ajmera, Divya Airan, Ranjeet Bairwa, Yogesh Meena","doi":"10.4103/2221-6189.390384","DOIUrl":"https://doi.org/10.4103/2221-6189.390384","url":null,"abstract":"\u0000 \u0000 To study the laboratory and clinical predictors of hemorrhagic manifestations in dengue virus-infected patients.\u0000 \u0000 \u0000 \u0000 This was a single-center hospital-based prospective observational study. 200 Dengue seropositive patients were included in the study. A detailed clinical examination was done and comprehensive laboratory investigations were done. These parameters were compared between patients with and without hemorrhagic manifestations.\u0000 \u0000 \u0000 \u0000 Out of the 200 patients, 47 (23.5%) had bleeding. 64.5% Patients were males and 76.0% were under the age of 40 years. The most common presenting symptoms were fever (100.0%) followed by myalgia (77.0%), nausea and vomiting (56.0%). Leukocytosis, neutrophilia, thrombocytopenia, hyperbilirubinemia, transaminitis, decreased serum albumins, and raised D-dimer can serve as hematological, biochemical, and coagulation predictors of hemorrhagic manifestations for dengue.\u0000 \u0000 \u0000 \u0000 Dengue is a tropical infection with various complications. Bleeding complications are one of them. Laboratory parameters like white blood cells, platelets, bilirubin level, liver enzymes, and D-dimer can help to identify patients at risk for bleeding. Early identification and appropriate management can save a lot of resources and lives.\u0000","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"161 ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139013826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 vaccine-related retinal vascular occlusion COVID-19 疫苗相关视网膜血管闭塞

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390391

Wai Yan Lam, Sunny Chi Lik Au

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Neurological manifestations of COVID-19 infection: A case series COVID-19感染的神经系统表现：病例系列

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390389

Ayimen Khalid Khan, Anam Khan, Ammar Khalid Khan, S. Anwar

引用次数: 0

A public health perspective on dengue in Bangladesh in the twenty-first century 从公共卫生角度看 21 世纪孟加拉国的登革热问题

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390392

Mehmet Uçar

引用次数: 0

Imipenem/cilastatin-induced acute eosinophilic pneumonia: A case report 亚胺培南/西司他丁诱发的急性嗜酸性粒细胞肺炎：病例报告

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390390

Gautam Jesrani, Samiksha Gupta, A. Lamba, S. Arora, Monica Gupta

{"title":"Imipenem/cilastatin-induced acute eosinophilic pneumonia: A case report","authors":"Gautam Jesrani, Samiksha Gupta, A. Lamba, S. Arora, Monica Gupta","doi":"10.4103/2221-6189.390390","DOIUrl":"https://doi.org/10.4103/2221-6189.390390","url":null,"abstract":"\u0000 \u0000 Acute eosinophilic pneumonia (AEP) is an acute pulmonary illness caused by eosinophilic infiltration of the lung parenchyma. It can happen after using drugs such as daptomycin and minocycline. AEP induced by imipenem/cilastatin is a rare condition.\u0000 \u0000 \u0000 \u0000 A 45-year-old male patient, who previously suffered from a urinary tract infection and treated with imipenem/cilastatin antibiotic, was presented to us with acute respiratory distress, soon after the initiation of the antibiotic. Computed tomography identified pulmonary infiltrates in the upper and middle lung fields and eosinophils were found to account for 36% of differential count of the broncho-alveolar lavage fluid. He also developed peripheral eosinophilia as the disease progressed.\u0000 \u0000 \u0000 \u0000 AEP, secondary to imipenem/cilastatin therapy.\u0000 \u0000 \u0000 \u0000 Steroid therapy was administered and imipenem/cilastatin antibiotic was discontinued.\u0000 \u0000 \u0000 \u0000 The patient improved completely following the therapy and had clear lung fields on follow-up.\u0000 \u0000 \u0000 \u0000 Imipenem/cilastatin is an uncommon cause of AEP and requires close monitoring during therapy.\u0000","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"122 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical profile of medication-related emergencies among patients presenting to the emergency department: An observational study 急诊科就诊患者中与药物相关急诊的临床概况：观察研究

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390386

Srilatha Yagadi, R. Guguloth, Mathews Jacob

{"title":"Clinical profile of medication-related emergencies among patients presenting to the emergency department: An observational study","authors":"Srilatha Yagadi, R. Guguloth, Mathews Jacob","doi":"10.4103/2221-6189.390386","DOIUrl":"https://doi.org/10.4103/2221-6189.390386","url":null,"abstract":"\u0000 \u0000 To determine the clinical profile of patients presenting with medication-related emergencies to the Emergency Department of our institute.\u0000 \u0000 \u0000 \u0000 This was an observational study conducted between November 2018 and September 2020 at Bangalore Baptist Hospital, Karnataka. A total of 138 subjects who satisfied the inclusion criteria were included in the study. The severity of adverse drug reactions (ADR) is assessed based on the Hurwitz severity assessment scale of ADR. Glasgow coma scale at the time of presentation and source of medication were noted. The type of drug overdose, requirement of advanced airway and vasopressors, and the outcome were also assessed.\u0000 \u0000 \u0000 \u0000 Among medication-related emergencies (n=138) in our study, ADR contributed to 70.3% (n=97) of the study population, and drug overdose accounted for 29.7% (n=41). One-third of the ADR occurred in patients aged above 60 years. Most patients were hemodynamically stable and did not require vasopressors, or advanced airway in both groups. Most patients had Glasgow coma scale ranging from 13-15 in both groups. Nonsteroidal anti-inflammatory drugs were the most used medicine (17/41, 41.5%) and most medications were over the counter drugs (25/41, 61.0%) in the drug overdose group; meanwhile in the ADR group, anti-diabetic medication was the most used medicine (34/97, 35.1%) and most medications were prescribed in the ADR group (93/97, 95.9%).\u0000 \u0000 \u0000 \u0000 Our study shows that ADR is the most common type of medication-related emergency.\u0000","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"673 ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for development of pneumothorax in patients with COVID-19 at a government health facility in North India: An exploratory case-control study 印度北部一家政府医疗机构的 COVID-19 患者发生气胸的风险因素：一项探索性病例对照研究

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390385

Manabendra Baidya, Sandeep Kumar Pandey, H. Solanki, Ankur Deep Singh, S. Giri, Syed Altamash

{"title":"Risk factors for development of pneumothorax in patients with COVID-19 at a government health facility in North India: An exploratory case-control study","authors":"Manabendra Baidya, Sandeep Kumar Pandey, H. Solanki, Ankur Deep Singh, S. Giri, Syed Altamash","doi":"10.4103/2221-6189.390385","DOIUrl":"https://doi.org/10.4103/2221-6189.390385","url":null,"abstract":"\u0000 \u0000 To explore risk factors for the development of pneumothorax in patients with COVID-19 during the second COVID-19 wave at a northern Indian level 2 health facility.\u0000 \u0000 \u0000 \u0000 Patients suffering from SARS-CoV-2 infection during the second wave of the COVID-19 pandemic in India (January -June 2021) at a tertiary care teaching hospital and level 2 COVID care facility were included. Cases who suffered from SARS-CoV-2 infection but did not develop pneumothorax were selected as matched controls. All details regarding demographics, clinical presentation, treatment, and outcome were recorded in a semi-structured proforma.\u0000 \u0000 \u0000 \u0000 Eleven patients with COVID-19 developed pneumothorax during the study period and 40 controls were included in the study. Five cases were smokers in comparison to only two in the control group. Type 2 diabetes mellitus was the most common comorbidity among both groups. Median change in C-reactive protein overall for cases and controls were around +14.0 and −41.9 and was statistically significant.\u0000 \u0000 \u0000 \u0000 Inflammatory markers like C-reactive protein have significant correlations with the development of pneumothorax in COVID-19-infected patients. There is no sex predisposition to develop pneumothorax among patients with COVID-19.\u0000","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"31 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138988268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 mortality trends before and after the national vaccination program in Iran: A joinpoint regression analysis 伊朗国家疫苗接种计划前后的 COVID-19 死亡率趋势：连接点回归分析

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Journal of Acute Disease Pub Date : 2023-12-01 DOI: 10.4103/2221-6189.390388

M. Sepandi, Y. Alimohamadi, Kolsoom Alimohamadi

{"title":"COVID-19 mortality trends before and after the national vaccination program in Iran: A joinpoint regression analysis","authors":"M. Sepandi, Y. Alimohamadi, Kolsoom Alimohamadi","doi":"10.4103/2221-6189.390388","DOIUrl":"https://doi.org/10.4103/2221-6189.390388","url":null,"abstract":"\u0000 \u0000 To investigate the trend of mortality by COVID-19 before and after the national vaccination program using joinpoint regression analysis from 19 February 2020 to 5 September 2022.\u0000 \u0000 \u0000 \u0000 In the present study, a joinpoint regression analysis of monthly collected data on confirmed deaths of COVID-19 in Iran from February 19, 2020 to September 5, 2022 was performed.\u0000 \u0000 \u0000 \u0000 After national vaccination in Iran, the trend of new monthly deaths due to COVID-19 was decreasing. The percentage of monthly changes from the beginning of the pandemic to the 19th month was 6.62% (95% CI: 1.1, 12.4), which had an increasing trend. From the 19th month to the end of the 31st month, the mortality trend was decreasing, and the percentage of monthly changes was −20.05% (95% CI: −8.3, −30.3) (P=0.002). The average percentage of monthly changes was −5% with a 95% CI of (−10.5, 0.9).\u0000 \u0000 \u0000 \u0000 Along with other health measures, such as quarantine, wearing a mask, hand washing, social distancing, etc., national vaccination significantly reduces the mortality rate of COVID-19.\u0000","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"427 ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139018256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical profile of febrile encephalopathy patients at a tertiary care hospital in India: A retrospective study 印度三级医院发热性脑病患者的临床概况:一项回顾性研究

Journal of Acute Disease Pub Date : 2023-01-01 DOI: 10.4103/2221-6189.385681

Jitesh Goel, Sanjeev Sengupta, AshishKumar Shukla, Kunal Kishore, Amlan Ghosh

{"title":"Clinical profile of febrile encephalopathy patients at a tertiary care hospital in India: A retrospective study","authors":"Jitesh Goel, Sanjeev Sengupta, AshishKumar Shukla, Kunal Kishore, Amlan Ghosh","doi":"10.4103/2221-6189.385681","DOIUrl":"https://doi.org/10.4103/2221-6189.385681","url":null,"abstract":"Objective: To investigate demography, etiology, and clinical profile and to analyze the outcomes of patients presenting with febrile encephalopathy at a tertiary care center in Eastern India. Methods: This retrospective, observational study included a total of 50 patients (>18 years) who presented with fever and encephalopathy. All patients underwent blood analysis; culture test for blood, urine, sputum, cerebrospinal fluid, and other body fluids; chest and abdominal ultrasonography; neuroimaging; polymerase chain reaction test, and other relevant tests as and when applicable. Results: The mean age of all enrolled patients was (58.0±16.0) years with male to female ratio of 1.27:1. Viral encephalitis was diagnosed in 16 (32%) patients, sepsis-associated encephalitis in 14 (28%), bacterial meningoencephalitis in 8 (16%) and tuberculosis meningoencephalitis in 5 (10%). The mean hospital stay was 10 (4, 17) days. At 6-month follow-up, 10 (20%) patients died, 10 (20%)patients recovered with sequelae (cognitive impairment, critical careneuropathy, etc.), and 30 (60%) patients recovered without sequelae. A statistically significant association was noted between GlasgowComa Scale (<8) and mortality rate (P=0.02). Conclusions: Primary central nervous system infection is the mostfrequent etiology of febrile encephalopathy and viral encephalitisis the most common etiological cause. Accurate, systematic, timelydiagnosis and management are prime factors to reduce mortality andmorbidity.","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"154 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135799468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0