{"title":"急诊科就诊患者中与药物相关急诊的临床概况:观察研究","authors":"Srilatha Yagadi, R. Guguloth, Mathews Jacob","doi":"10.4103/2221-6189.390386","DOIUrl":null,"url":null,"abstract":"\n \n To determine the clinical profile of patients presenting with medication-related emergencies to the Emergency Department of our institute.\n \n \n \n This was an observational study conducted between November 2018 and September 2020 at Bangalore Baptist Hospital, Karnataka. A total of 138 subjects who satisfied the inclusion criteria were included in the study. The severity of adverse drug reactions (ADR) is assessed based on the Hurwitz severity assessment scale of ADR. Glasgow coma scale at the time of presentation and source of medication were noted. The type of drug overdose, requirement of advanced airway and vasopressors, and the outcome were also assessed.\n \n \n \n Among medication-related emergencies (n=138) in our study, ADR contributed to 70.3% (n=97) of the study population, and drug overdose accounted for 29.7% (n=41). One-third of the ADR occurred in patients aged above 60 years. Most patients were hemodynamically stable and did not require vasopressors, or advanced airway in both groups. Most patients had Glasgow coma scale ranging from 13-15 in both groups. Nonsteroidal anti-inflammatory drugs were the most used medicine (17/41, 41.5%) and most medications were over the counter drugs (25/41, 61.0%) in the drug overdose group; meanwhile in the ADR group, anti-diabetic medication was the most used medicine (34/97, 35.1%) and most medications were prescribed in the ADR group (93/97, 95.9%).\n \n \n \n Our study shows that ADR is the most common type of medication-related emergency.\n","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"673 ","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical profile of medication-related emergencies among patients presenting to the emergency department: An observational study\",\"authors\":\"Srilatha Yagadi, R. Guguloth, Mathews Jacob\",\"doi\":\"10.4103/2221-6189.390386\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n \\n To determine the clinical profile of patients presenting with medication-related emergencies to the Emergency Department of our institute.\\n \\n \\n \\n This was an observational study conducted between November 2018 and September 2020 at Bangalore Baptist Hospital, Karnataka. A total of 138 subjects who satisfied the inclusion criteria were included in the study. The severity of adverse drug reactions (ADR) is assessed based on the Hurwitz severity assessment scale of ADR. Glasgow coma scale at the time of presentation and source of medication were noted. The type of drug overdose, requirement of advanced airway and vasopressors, and the outcome were also assessed.\\n \\n \\n \\n Among medication-related emergencies (n=138) in our study, ADR contributed to 70.3% (n=97) of the study population, and drug overdose accounted for 29.7% (n=41). One-third of the ADR occurred in patients aged above 60 years. Most patients were hemodynamically stable and did not require vasopressors, or advanced airway in both groups. Most patients had Glasgow coma scale ranging from 13-15 in both groups. Nonsteroidal anti-inflammatory drugs were the most used medicine (17/41, 41.5%) and most medications were over the counter drugs (25/41, 61.0%) in the drug overdose group; meanwhile in the ADR group, anti-diabetic medication was the most used medicine (34/97, 35.1%) and most medications were prescribed in the ADR group (93/97, 95.9%).\\n \\n \\n \\n Our study shows that ADR is the most common type of medication-related emergency.\\n\",\"PeriodicalId\":45984,\"journal\":{\"name\":\"Journal of Acute Disease\",\"volume\":\"673 \",\"pages\":\"\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Acute Disease\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4103/2221-6189.390386\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Acute Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/2221-6189.390386","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Clinical profile of medication-related emergencies among patients presenting to the emergency department: An observational study
To determine the clinical profile of patients presenting with medication-related emergencies to the Emergency Department of our institute.
This was an observational study conducted between November 2018 and September 2020 at Bangalore Baptist Hospital, Karnataka. A total of 138 subjects who satisfied the inclusion criteria were included in the study. The severity of adverse drug reactions (ADR) is assessed based on the Hurwitz severity assessment scale of ADR. Glasgow coma scale at the time of presentation and source of medication were noted. The type of drug overdose, requirement of advanced airway and vasopressors, and the outcome were also assessed.
Among medication-related emergencies (n=138) in our study, ADR contributed to 70.3% (n=97) of the study population, and drug overdose accounted for 29.7% (n=41). One-third of the ADR occurred in patients aged above 60 years. Most patients were hemodynamically stable and did not require vasopressors, or advanced airway in both groups. Most patients had Glasgow coma scale ranging from 13-15 in both groups. Nonsteroidal anti-inflammatory drugs were the most used medicine (17/41, 41.5%) and most medications were over the counter drugs (25/41, 61.0%) in the drug overdose group; meanwhile in the ADR group, anti-diabetic medication was the most used medicine (34/97, 35.1%) and most medications were prescribed in the ADR group (93/97, 95.9%).
Our study shows that ADR is the most common type of medication-related emergency.
期刊介绍:
The articles published mainly deal with pre-hospital and hospital emergency medicine, cardiopulmonary-cerebral resuscitation, critical cardiovascular disease, sepsis, severe infection, multiple organ failure, acute and critical diseases in different medical fields, sudden cardiac arrest, Intensive Care Unit (ICU), critical care medicine, disaster rescue medicine (earthquakes, fires, floods, mine disaster, air crash, et al.), acute trauma, acute toxicology, acute heart disease, and related topics. JAD sets up columns for special subjects in each issue.