S. Jelia, Devendra Ajmera, Divya Airan, Ranjeet Bairwa, Yogesh Meena
{"title":"Predictors of hemorrhagic manifestations in dengue: A prospective observational study from the Hadoti region of Rajasthan","authors":"S. Jelia, Devendra Ajmera, Divya Airan, Ranjeet Bairwa, Yogesh Meena","doi":"10.4103/2221-6189.390384","DOIUrl":null,"url":null,"abstract":"\n \n To study the laboratory and clinical predictors of hemorrhagic manifestations in dengue virus-infected patients.\n \n \n \n This was a single-center hospital-based prospective observational study. 200 Dengue seropositive patients were included in the study. A detailed clinical examination was done and comprehensive laboratory investigations were done. These parameters were compared between patients with and without hemorrhagic manifestations.\n \n \n \n Out of the 200 patients, 47 (23.5%) had bleeding. 64.5% Patients were males and 76.0% were under the age of 40 years. The most common presenting symptoms were fever (100.0%) followed by myalgia (77.0%), nausea and vomiting (56.0%). Leukocytosis, neutrophilia, thrombocytopenia, hyperbilirubinemia, transaminitis, decreased serum albumins, and raised D-dimer can serve as hematological, biochemical, and coagulation predictors of hemorrhagic manifestations for dengue.\n \n \n \n Dengue is a tropical infection with various complications. Bleeding complications are one of them. Laboratory parameters like white blood cells, platelets, bilirubin level, liver enzymes, and D-dimer can help to identify patients at risk for bleeding. Early identification and appropriate management can save a lot of resources and lives.\n","PeriodicalId":45984,"journal":{"name":"Journal of Acute Disease","volume":"161 ","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Acute Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/2221-6189.390384","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
To study the laboratory and clinical predictors of hemorrhagic manifestations in dengue virus-infected patients.
This was a single-center hospital-based prospective observational study. 200 Dengue seropositive patients were included in the study. A detailed clinical examination was done and comprehensive laboratory investigations were done. These parameters were compared between patients with and without hemorrhagic manifestations.
Out of the 200 patients, 47 (23.5%) had bleeding. 64.5% Patients were males and 76.0% were under the age of 40 years. The most common presenting symptoms were fever (100.0%) followed by myalgia (77.0%), nausea and vomiting (56.0%). Leukocytosis, neutrophilia, thrombocytopenia, hyperbilirubinemia, transaminitis, decreased serum albumins, and raised D-dimer can serve as hematological, biochemical, and coagulation predictors of hemorrhagic manifestations for dengue.
Dengue is a tropical infection with various complications. Bleeding complications are one of them. Laboratory parameters like white blood cells, platelets, bilirubin level, liver enzymes, and D-dimer can help to identify patients at risk for bleeding. Early identification and appropriate management can save a lot of resources and lives.
期刊介绍:
The articles published mainly deal with pre-hospital and hospital emergency medicine, cardiopulmonary-cerebral resuscitation, critical cardiovascular disease, sepsis, severe infection, multiple organ failure, acute and critical diseases in different medical fields, sudden cardiac arrest, Intensive Care Unit (ICU), critical care medicine, disaster rescue medicine (earthquakes, fires, floods, mine disaster, air crash, et al.), acute trauma, acute toxicology, acute heart disease, and related topics. JAD sets up columns for special subjects in each issue.