Acta Dermatovenerologica Alpina Pannonica et Adriatica最新文献_第4页

Clinical and immunopathological characteristics of autoimmune blistering skin diseases. 自身免疫性大疱性皮肤病的临床和免疫病理特征。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Anita Gunarić, Dubravka Šimić, Branka Marinović

引用次数: 0

Efficacy of alitretinoin in the treatment of Darier disease: a case report. 阿利替诺治疗达里尔病的疗效：病例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Andreja Pagon, Mateja Dolenc Voljč

引用次数: 0

New anti-aging strategies: a narrative review. 新的抗衰老战略：叙述性综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Vana Stojić, Tea Štrbac, Andrija Stanimirović

{"title":"New anti-aging strategies: a narrative review.","authors":"Vana Stojić, Tea Štrbac, Andrija Stanimirović","doi":"","DOIUrl":"","url":null,"abstract":"The objective of anti-aging medicine is to decelerate the aging process and mitigate its associated effects, such as susceptibility to cancer, diabetes, and cardiovascular and neurodegenerative diseases. This review provides an overview of the latest advancements in this field, considering both pharmaceutical and non-pharmaceutical approaches. Electronic literature search involved three databases: MEDLINE, Cochrane, and Google Scholar, supplemented by other available literature. Strategies for delaying aging and related diseases comprise pharmaceutical interventions and lifestyle choices. It is crucial for these strategies to be substantiated by research-based evidence. Lifestyle options include fasting, fasting-mimicking, and ketogenic diets. Anti-aging drugs and supplements operate through diverse mechanisms. Calorie restriction mimetics include the activator of AMP-activated protein kinase (metformin) and inhibitor of mTOR (rapamycin), alongside rilmenidine, exhibiting both effects. Rosmarinic acid, a natural product, functions through its anti-glycation properties. Age-related protein crosslinks are acknowledged as a causative factor in age-related diseases. Anti-aging medicine is an evolving field with a multitude of drugs and strategies, necessitating further clinical studies and long-term follow-up based on clinical experience and insights gained from delayed adverse events.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 4","pages":"159-164"},"PeriodicalIF":1.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute onset of leukemia cutis in a 70-year-old-patient: a case report. 一名 70 岁患者的急性切口白血病：病例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Maruša Selan, Neža Stopajnik

引用次数: 0

Different skin wart types, different human papillomavirus types? A narrative review. 皮肤疣类型不同，人类乳头瘤病毒类型也不同？综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Lucijan Skubic, Vesna Breznik, Mario Poljak

引用次数: 0

Evaluation of corticophobia in patients with atopic dermatitis and psoriasis using the TOPICOP© score. 使用 TOPICOP© 评分评估特应性皮炎和银屑病患者的恐皮质症。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Mateja Starbek Zorko, Maja Benko, Mateja Rakuša, Tanja Prunk Zdravković

{"title":"Evaluation of corticophobia in patients with atopic dermatitis and psoriasis using the TOPICOP© score.","authors":"Mateja Starbek Zorko, Maja Benko, Mateja Rakuša, Tanja Prunk Zdravković","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Atopic dermatitis (AD) and psoriasis (PS) are skin diseases that have a significant impact on the quality of life. The correct application of corticosteroids in topical treatment is highly effective and safe for patients. Excessive and irrational fear of these drugs based on incorrect information is increasingly observed at dermatological clinics.Methods: To assess the extent of corticophobia, we conducted a single-center cross-sectional survey using the TOPICOP© questionnaire.Results: The study included 57 patients (56% female) with AD and 58 patients (60% female) with PS. The combined TOPICOP© score averaged around 44, showing no significant difference between the two skin conditions. However, consistently higher scores were observed among female participants compared to males.Conclusions: The prevalence of corticophobia was comparable to that reported in other similar studies and was higher among female patients, which replicates previous findings. Patients with AD, who were younger on average than patients with PS, often relied on friends, acquaintances, family members, and the internet as their main information sources. Providing correct and reliable information to patients is crucial for ensuring treatment adherence.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 4","pages":"135-139"},"PeriodicalIF":1.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunohistochemical expression of vitamin D receptor and Wnt signaling pathway molecules in psoriasis. 银屑病中维生素 D 受体和 Wnt 信号通路分子的免疫组化表达。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Amina Ismaeel, Fatima Alhashimi, Zainab Almossali, Safa Alshaikh, Samvel Selvam, Duha Janahi

{"title":"Immunohistochemical expression of vitamin D receptor and Wnt signaling pathway molecules in psoriasis.","authors":"Amina Ismaeel, Fatima Alhashimi, Zainab Almossali, Safa Alshaikh, Samvel Selvam, Duha Janahi","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Psoriasis is a prevalent, complex, immune-mediated illness. There is some evidence in the literature supporting the involvement of the Wnt signaling pathway in psoriasis. No previous studies have focused on the association between the Wnt signaling pathway and vitamin D receptor (VDR) expression in psoriasis. This study investigates the expression of VDR and mediators of the canonical (β-catenin) and non-canonical (Wnt5a) Wnt signaling pathway in psoriatic lesional skin biopsy specimens compared to controls.Methods: A cross-sectional study conducted on skin punch biopsy specimens from 42 psoriasis patients were stained with VDR, β-catenin, and Wnt5a and compared with 42 control biopsies. Patients' demographics, clinical data, and serum vitamin D levels were recorded.Results: VDR showed nuclear localization with significant downregulation in the psoriasis specimens compared to controls. β-catenin (membranous) and Wnt5a (cytoplasmic) showed significant upregulation in the psoriasis specimens. When the expressions of VDR, β-catenin, and Wnt5a were compared based on disease severity, no differences were found between mild, moderate, and severe subgroups of the disease. Late-onset psoriasis patients had lower VDR and Wnt5a histoscores compared to the early-onset group. A trend toward a positive correlation was observed between the histoscores of VDR and Wnt5a.Conclusion: Our findings confirm the significance of VDR signaling in the pathophysiology of psoriasis and strengthen the relationship between this disease and the Wnt signaling pathway. There was evidence that there is an association between VDR status and Wnt5a expression.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 4","pages":"129-133"},"PeriodicalIF":1.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in trichotillomania: a narrative review. 毛发增多症的最新进展：叙述性综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Rachel E Christensen, Isabella Tan, Mohammad Jafferany

引用次数: 0

A dermatological perspective: eosinophilic eruption of hematoproliferative disease as a clinical and histological dilemma. 皮肤病学视角：血液增生性疾病的嗜酸性粒细胞爆发是临床和组织学难题。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Tijana Orlic, Snezana Minic, Emilija Manojlovic-Gacic, Dubravka Zivanovic, Igor Kapetanovic

{"title":"A dermatological perspective: eosinophilic eruption of hematoproliferative disease as a clinical and histological dilemma.","authors":"Tijana Orlic, Snezana Minic, Emilija Manojlovic-Gacic, Dubravka Zivanovic, Igor Kapetanovic","doi":"","DOIUrl":"","url":null,"abstract":"The emergence of de novo or recurrent cutaneous eruptions in individuals with hematological diseases presents a challenge when determining whether they indicate secondary dissemination or an unrelated diagnosis. Eosinophilic eruption of hematoproliferative disease is a rare nonspecific manifestation accompanying lymphoproliferative disorders, including chronic lymphocytic leukemia (CLL). We present the case of a 70-year-old man with CLL in remission (previously treated with two 6-month cycles of fludarabine-cyclophosphamide plus rituximab, 2 and 5 years earlier) with an acute, disseminated polymorphic skin eruption. Skin biopsies from two sites (bulla and infiltrated nodule) were taken for histopathological examination. The pathologist reported giant spongiform vesicle formation with eosinophils with dermal and hypodermal inflammatory infiltrate composed of lymphocytes (predominantly T cells, fewer B cells) and eosinophils. Secondary neoplasm dissemination and sarcoidosis were excluded by means of immunohistochemistry. A diagnosis of eosinophilic eruption of hematoproliferative disease in the CLL patient post-chemotherapy and without active disease was established. Two weeks after skin remission, the patient worsened with enlarged lymph nodes and a leukocyte count of 291 × 10^9/l. CLL relapse was confirmed. Leukocytapheresis was performed and ibrutinib 140 mg three times daily was prescribed. Our case underscores the importance of recognizing this relatively common but underreported eosinophilic eruption associated with hematoproliferative diseases.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 4","pages":"183-186"},"PeriodicalIF":1.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous manifestations of the COVID-19 pandemic in schoolchildren and adolescents. 学龄儿童和青少年的 COVID-19 皮肤表现。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Daniela Franulić, Ena Parać, Lorena Dolački, Iva Topalušić, Liborija Lugović-Mihić

{"title":"Cutaneous manifestations of the COVID-19 pandemic in schoolchildren and adolescents.","authors":"Daniela Franulić, Ena Parać, Lorena Dolački, Iva Topalušić, Liborija Lugović-Mihić","doi":"","DOIUrl":"","url":null,"abstract":"This review article focuses on cutaneous manifestations in schoolchildren and adolescents 6 to 18 years old connected with various aspects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, including personal protective equipment (PPE), SARS-CoV-2 infection, and the SARS-CoV-2 vaccine. The use of PPE has been associated with mask-related acne due to microbiome dysbiosis and disruption of skin homeostasis, leading to the emergence of new acne or exacerbation of preexisting acne. Chilblain-like lesions, erythema multiforme-like eruptions, and cutaneous manifestations of multisystem inflammatory syndrome related to SARS-CoV-2 are the most commonly described skin manifestations of SARS-CoV-2 infection. The proposed mechanisms involve either the direct interaction of the virus with the skin through cutaneous receptor angiotensin-converting enzyme 2 in the epidermal basal layer or hyperactive immune responses. The impact of SARS-CoV-2 infection has also been described on adnexa, including hair changes such as alopecia areata and telogen effluvium, as well as nail changes presenting as onychomadesis and periungual desquamation. Cutaneous adverse effects of the SARS-CoV-2 vaccine have been described in case reports and differ from those in adults. Therefore, there is a need for increased awareness regarding the most prevalent cutaneous manifestations associated with COVID-19 in children because they tend to be mild or nonspecific in nature.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 4","pages":"173-181"},"PeriodicalIF":1.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0