Acta Dermatovenerologica Alpina Pannonica et Adriatica最新文献_第5页

Digging into uncertainty: a case report on Spitz lesions. 挖掘不确定因素：关于斯皮茨病变的病例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Eva Klara Merzel Šabović, Dragan Jejinić, Andreja Pagon, Nina Jugovar, Violeta Hosta

引用次数: 0

Review of virological methods for laboratory diagnosis and characterization of monkeypox virus (MPXV): lessons learned from the 2022 Mpox outbreak. 猴痘病毒（MPXV）实验室诊断和定性的病毒学方法回顾：从 2022 年猴痘爆发中吸取的经验教训。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Marko Kolenc, Lucijan Skubic, Nataša Knap, Misa Korva, Mario Poljak, Tatjana Avšič-Županc

{"title":"Review of virological methods for laboratory diagnosis and characterization of monkeypox virus (MPXV): lessons learned from the 2022 Mpox outbreak.","authors":"Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Marko Kolenc, Lucijan Skubic, Nataša Knap, Misa Korva, Mario Poljak, Tatjana Avšič-Županc","doi":"","DOIUrl":"","url":null,"abstract":"Monkeypox virus (MPXV), originally endemic in West Africa (Clade II) and Central Africa (Clade I), has recently emerged worldwide and has reinforced the need for rapid and accurate MPXV diagnostics. This review presents and critically discusses the range of virological methods for laboratory diagnosis and characterization of MPXV as well as related lessons learned and practical experience gained from the 2022 Mpox global outbreak. Real-time PCR is currently considered the diagnostic gold standard and ensures accurate and timely confirmation of suspected Mpox cases based on suspicious skin lesions, and digital PCR improves the precision of MPXV DNA quantification. Whole genome sequencing reveals the diversity within the Clade IIb outbreak and highlights the role of microevolution in the adaptation of the virus to the human host. Continuous genomic surveillance is important for better understanding of human-to-human transmission and prevention of the emergence of variola virus-like strains. Traditional virological methods such as electron microscopy and virus isolation remain essential for comprehensive virus characterization, particularly in the context of vaccine and antiviral drug development. Despite the current challenges, serological tests detecting a range of anti-MPXV antibodies are important adjunct diagnostic and research tools for confirmation of late-presenting or asymptomatic MPXV cases, contact tracing, epidemiological studies, seroepidemiological surveys, and better understanding of the role of IgG and neutralizing antibodies in the immune response to infection and vaccination. A multidisciplinary approach combining advanced molecular techniques with traditional virological methods is important for rapid and reliable diagnosis, surveillance, and control of the outbreak.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"23-35"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and oral lesions: 2020-2024 outpatient case series and literature review. COVID-19 与口腔病变：2020-2024 年门诊病例系列和文献综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Ana Glavina, Jozo Badrov, Marino Lukenda, Karmela Džaja, Dolores Biočina-Lukenda, Liborija Lugović-Mihić

{"title":"COVID-19 and oral lesions: 2020-2024 outpatient case series and literature review.","authors":"Ana Glavina, Jozo Badrov, Marino Lukenda, Karmela Džaja, Dolores Biočina-Lukenda, Liborija Lugović-Mihić","doi":"","DOIUrl":"","url":null,"abstract":"Data on oral lesions of coronavirus disease (COVID-19) are conflicting, and there are few evidence-based data on oral lesions directly caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this case series and literature review is to determine the prevalence of oral lesions associated with COVID-19 in outpatients and identify oral manifestations that are likely associated with COVID-19. We present 15 patients that came for their first specialist examination to the Oral Medicine Outpatient Clinic, Dental Clinic, Split, Croatia between November 2020 and January 2024. Their medical and dental history was taken following CARE guidelines. The prevalence of oral lesions associated with SARS-CoV-2 was 1.42% during the 4-year follow-up period. The most common oral lesions were nonspecific erosions, stomatitis, salivary flow disorders (xerostomia, oligosialia), salivary gland diseases (sialadenitis, chronic sialadenitis), candidiasis, pigmentation, aphthae, burning mouth syndrome, and geographic and fissured tongue. The mean latency period was 25.1 days. The site most commonly affected was the tongue (61.5%). Oral lesions associated with COVID-19 occurred in middle-aged patients, with an equal distribution by sex. They presented in a mild form and did not correlate with the severity of the clinical picture of COVID-19.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"41-48"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between sleep quality and chronotype differences and urticaria severity in patients with chronic spontaneous urticaria. 慢性自发性荨麻疹患者的睡眠质量和时间型差异与荨麻疹严重程度之间的关系。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Gulhan Gurel, Dilara Guler, Hasan Ali Guler, İrem Nur Durusu Türkoğlu, Isın Nur Sultan Oncu, Seçil Soylu

{"title":"The relationship between sleep quality and chronotype differences and urticaria severity in patients with chronic spontaneous urticaria.","authors":"Gulhan Gurel, Dilara Guler, Hasan Ali Guler, İrem Nur Durusu Türkoğlu, Isın Nur Sultan Oncu, Seçil Soylu","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Chronic spontaneous urticaria (CSU) is characterized by persistent or recurrent pruritic lesions that last more than 6 weeks. Patients with CSU may experience sleep disturbances, particularly due to itching. Biological rhythms (chronotypes) are categorized as morningness, intermediate, and eveningness types. This study evaluates the relationship between sleep quality, chronotype, and disease severity in CSU patients.Methods: The study included 53 CSU patients and 50 healthy controls. A sociodemographic data form was completed, and the disease severity was determined utilizing the Urticaria Activity Score over 7 days (UAS7). The Hospital Anxiety and Depression Scale (HADS), Insomnia Severity Index (ISI), and Pittsburgh Sleep Quality Index (PSQI) scales as well as the Morningness-Eveningness Scale (MEQ) were applied to the participants.Results: The CSU group had a significantly higher body mass index (BMI) than that of the healthy control group. In terms of sleep and chronotype scales, compared to the control group, the CSU group had higher ISI scores as well as subscale scores on the PSQI subscales, with the exception of habitual sleep efficiency and total PSQI scores. There was no difference between MEQ scores. In the correlation analysis, the UAS7 and PSQI total scores were found to be correlated, whereas in the logistic regression analysis the estimated relative risk of BMI and PSQI total score for CSU was found to be 1.13 and 1.45, respectively.Conclusions: When dealing with CSU patients, it is necessary to conduct a sleep quality assessment as part of a holistic evaluation.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"7-11"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Widespread dermatophytosis in a healthy adolescent: the first report of multidrug-resistant Trichophyton indotineae infection in the UAE. 一名健康青少年的大面积皮肤癣菌病：阿联酋首例耐多药毛癣菌感染病例。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Miloš D Pavlović, Shireen Marzouk, Leis Bećiri

引用次数: 0

Diagnostic accuracy of a short-form version of the diagnostic criteria for primary hyperhidrosis. 原发性多汗症诊断标准简表的诊断准确性。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Mattias A S Henning, Hajer I Al-Rahimi, Gregor B E Jemec, Ole B Pedersen

{"title":"Diagnostic accuracy of a short-form version of the diagnostic criteria for primary hyperhidrosis.","authors":"Mattias A S Henning, Hajer I Al-Rahimi, Gregor B E Jemec, Ole B Pedersen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The gold standard method for diagnosing primary hyperhidrosis (PHH) is based on seven patient-reported criteria. By determining an individual criterion's diagnostic accuracy, one can identify short-version classification models.Methods: In this cross-sectional study, data were collected from Danish blood donors in 2021. Cohen's kappa and diagnostic accuracy were determined by comparing each criterion with the gold standard method.Results: The study included 1,039 participants. Of them, 59 (5.7%) had PHH and 980 (94.3%) were classified as control individuals. The PHH major criterion \"focal visible excessive sweating for at least 6 months without an apparent cause\" had the highest prevalence in the participants with PHH compared to the control individuals (100% vs. 0.6%; p < 0.0001). The agreement between this criterion and PHH was Cohen's kappa = 0.95 (95% confidence interval [CI] 0.91-0.99), and its sensitivity was 1.00 (95% CI 0.94-1.00) and specificity 0.99 (95% CI 0.99-1.00). The other criteria showed lower agreement and diagnostic accuracy.Conclusions: The PHH major criterion showed near-perfect agreement and near-equal diagnostic accuracy compared with the gold standard method. This single criterion can be used as a short-form version to screen for PHH. Determination of reproducibility in independent populations is warranted.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"17-22"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hereditary angioedema: do patients have a specific "digital fingerprint" in Danish registries? 遗传性血管性水肿：丹麦登记册中的患者有特定的 "数字指纹 "吗？

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Jakob Lillemoen Drivenes

{"title":"Hereditary angioedema: do patients have a specific \"digital fingerprint\" in Danish registries?","authors":"Jakob Lillemoen Drivenes","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Hereditary angioedema (HAE) is a potentially life-threatening genetic disorder characterized by recurrent episodes of angioedema. From the onset of symptoms until diagnosis, patients often have several contacts with the healthcare system. It was hypothesized that a \"digital fingerprint\" of undiagnosed HAE patients could be identified in Danish registries.Methods: This study compared patients with a control group of patients with a diagnosis of Quincke's edema (QE) or bee/wasp allergy because they could have phenotypic similarities.Results: QE was the most common diagnosis code in the hospital sector among HAE patients before a specific diagnosis of HAE was established. HAE patients had been seen at the hospital on average once every other year before the diagnosis was established, and on average once during the year before the diagnosis was established. Many patients contacted a practicing dermatologist during the year before the diagnosis was established.Conclusions: HAE patients had several hospital contacts due to swelling attacks during the years before their diagnosis was established, and half of them consulted a dermatologist. It was not possible to identify a specific \"digital fingerprint\" in Danish registries regarding specific procedures or diagnoses distinguishing them from the control group. It is therefore recommended that hospitalized patients with angioedema of unknown cause be screened for HAE.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"13-16"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and immunopathological characteristics of autoimmune blistering skin diseases. 自身免疫性大疱性皮肤病的临床和免疫病理特征。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Anita Gunarić, Dubravka Šimić, Branka Marinović

引用次数: 0

Efficacy of alitretinoin in the treatment of Darier disease: a case report. 阿利替诺治疗达里尔病的疗效：病例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Andreja Pagon, Mateja Dolenc Voljč

引用次数: 0

New anti-aging strategies: a narrative review. 新的抗衰老战略：叙述性综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2023-12-01

Vana Stojić, Tea Štrbac, Andrija Stanimirović

{"title":"New anti-aging strategies: a narrative review.","authors":"Vana Stojić, Tea Štrbac, Andrija Stanimirović","doi":"","DOIUrl":"","url":null,"abstract":"The objective of anti-aging medicine is to decelerate the aging process and mitigate its associated effects, such as susceptibility to cancer, diabetes, and cardiovascular and neurodegenerative diseases. This review provides an overview of the latest advancements in this field, considering both pharmaceutical and non-pharmaceutical approaches. Electronic literature search involved three databases: MEDLINE, Cochrane, and Google Scholar, supplemented by other available literature. Strategies for delaying aging and related diseases comprise pharmaceutical interventions and lifestyle choices. It is crucial for these strategies to be substantiated by research-based evidence. Lifestyle options include fasting, fasting-mimicking, and ketogenic diets. Anti-aging drugs and supplements operate through diverse mechanisms. Calorie restriction mimetics include the activator of AMP-activated protein kinase (metformin) and inhibitor of mTOR (rapamycin), alongside rilmenidine, exhibiting both effects. Rosmarinic acid, a natural product, functions through its anti-glycation properties. Age-related protein crosslinks are acknowledged as a causative factor in age-related diseases. Anti-aging medicine is an evolving field with a multitude of drugs and strategies, necessitating further clinical studies and long-term follow-up based on clinical experience and insights gained from delayed adverse events.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"32 4","pages":"159-164"},"PeriodicalIF":1.2,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0