色素性光化性扁平苔藓:病例报告。

IF 0.6 Q4 DERMATOLOGY
Katarina Đorđević, Jovan Lalošević, Miloš Nikolić
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引用次数: 0

摘要

日光性扁平苔藓(ALP)是扁平苔藓(LP)中一种罕见的光敏性亚型,主要有四种类型:环状型、色素沉着型(黄褐斑样)、色素失调型和典型苔癣型。居住在热带和亚热带地区的黑皮肤年轻女性发病率最高。欧洲有关 ALP 的报道很少,大多数病例都是生活在温暖国家的人或有中东和印度血统的人。我们报告了一例 68 岁的白人男性病例,他的鼻尖出现轻度瘙痒的单发色素沉着斑已有 9 年病史。组织病理学检查显示了典型的 LP 征,伴有表皮萎缩、色素失禁和日光性松弛症。根据这些检查结果,确定了色素性 ALP 的诊断。外用吡美莫司和曲安奈德以及严格的光防护证明是有效的,治疗 6 个月后,色素沉着仍有轻度残留。对于这种病变,应考虑许多鉴别诊断的可能性。不过,活组织检查和组织病理学与临床结果的相关性可以缩短从发病到确诊的时间。有必要同时治疗这种皮肤病的色素沉着和炎症部分,并进行严格的长期光防护以防止复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pigmented actinic lichen planus: a case report.

Actinic lichen planus (ALP) is a rare photosensitive subtype of lichen planus (LP) with four major forms recognized: annular, pigmented (melasma-like), dyschromic, and classic lichenoid. The prevalence is highest among dark-skinned younger females residing in tropical and subtropical regions. There are very few reports of ALP across Europe, with most of the cases among individuals living in warm countries or in people of Middle Eastern and Indian ancestry. We report a case of a 68-year-old white man that presented with a 9-year history of a mildly pruritic solitary hyperpigmented patch on the tip of his nose. Histopathological examination demonstrated signs of classic LP with epidermal atrophy, pigmentary incontinence, and signs of solar elastosis. Based on these findings, a diagnosis of pigmented ALP was established. Topical pimecrolimus and tretinoin along with rigorous photoprotection proved effective, with mild residual hyperpigmentation after 6 months of treatment. Many differential diagnostic possibilities should be considered for such a lesion. Nevertheless, a biopsy and correlation of histopathological and clinical findings can shorten the time from onset to a proper diagnosis. Treating both the hyperpigmented and inflammatory component of this dermatosis is necessary, as well as strict long-term photoprotection to prevent recurrences.

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来源期刊
CiteScore
1.70
自引率
8.30%
发文量
38
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