Acta Dermatovenerologica Alpina Pannonica et Adriatica最新文献_第3页

The effectiveness and safety of 3% tranexamic acid cream vs. 4% hydroquinone cream for mixed-type melasma in skin of color: a double-blind, split-face, randomized controlled trial. 3% 氨甲环酸乳膏与 4% 氢醌乳膏治疗有色人种混合型黄褐斑的有效性和安全性：双盲、分面随机对照试验。

IF 0.6

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-06-01

Nevi Yasnova, Sondang P Sirait, Githa Rahmayunita

{"title":"The effectiveness and safety of 3% tranexamic acid cream vs. 4% hydroquinone cream for mixed-type melasma in skin of color: a double-blind, split-face, randomized controlled trial.","authors":"Nevi Yasnova, Sondang P Sirait, Githa Rahmayunita","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Melasma, a chronic acquired skin pigmentation disorder, is characterized by the presence of irregular-edged brown to gray-brown patches with a symmetrical distribution, primarily on sun-exposed areas such as the face. Topical hydroquinone (HQ) is the gold standard for melasma treatment but has numerous side effects. This study assesses the effectiveness of topical tranexamic acid (TA) as an alternative for melasma treatment.Methods: In a double-blind, split-face, randomized controlled trial involving 20 subjects, the effectiveness of 3% TA versus 4% HQ cream was evaluated over 8 weeks. The modified melasma area and severity index (mMASI), melanin index, erythema index, and side effects were assessed. Subjective improvement was measured using the patient global assessment (PtGA).Results: A significant decline in the mMASI score was observed at weeks 4 and 8 in both groups compared to baseline. There were no statistically significant differences in PtGA scores between the 3% TA group and the 4% HQ group.Conclusions: Topical 3% TA is as effective and safe as 4% HQ for treating melasma in the Indonesian population, with potential advantages in terms of side-effect profiles.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 2","pages":"83-88"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoaging assessment by Glogau classification: correlation of dermoscopy findings in the coastal population of Indonesia. 用 Glogau 分类法评估光老化：印度尼西亚沿海居民皮肤镜检查结果的相关性。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Putu Martha Gerynda Sukma, Sri Linuwih Sw Menaldi, Larisa Paramitha Wibawa, Shannaz Nadia Yusharyahya, Marsen Isbayuputra

{"title":"Photoaging assessment by Glogau classification: correlation of dermoscopy findings in the coastal population of Indonesia.","authors":"Putu Martha Gerynda Sukma, Sri Linuwih Sw Menaldi, Larisa Paramitha Wibawa, Shannaz Nadia Yusharyahya, Marsen Isbayuputra","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: To date, there is no gold standard for identifying photoaging. This study investigates the correlation of photoaging profiles based on the Glogau scale and the dermoscopy photoaging scale (DPAS) in a coastal population.Methods: An analytical cross-sectional study was conducted at Cilincing Municipal Health Center in Jakarta in October 2022. Individuals living in the coastal area, 20 years and older, with Fitzpatrick skin types III-V, and with a mean daily sun exposure of ≥ 3 hours were included. The Glogau scale and DPAS were assessed through history taking, physical examination, and dermoscopic examination. A Spearman correlation test was used to assess the correlation between the Glogau scale and DPAS.Results: Thirty individuals with a mean age of 41.5 ± 11.5 years participated in the study. The median Glogau score was 3 (range: 2-4). The mean DPAS score was 28.5 ± 5.6. Lentigo, hypo-hyperpigmented macules, telangiectasia, deep wrinkles, and superficial wrinkles were observed in all subjects. There was a moderate positive correlation between the Glogau scale and DPAS (r = 0.536, p = 0.002).Conclusions: The Glogau scale has a significant correlation with DPAS. DPAS can serve as a reliable, easy, practical, and fast diagnostic tool to assess the severity of aging.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"1-5"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of plaque-psoriasis in HIV-positive patients. 治疗艾滋病毒阳性患者的斑块状银屑病。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Vita Jugovac, Marija Gulin, Dora Barić, Daniela Ledić Drvar, Romana Čeović

{"title":"Treatment of plaque-psoriasis in HIV-positive patients.","authors":"Vita Jugovac, Marija Gulin, Dora Barić, Daniela Ledić Drvar, Romana Čeović","doi":"","DOIUrl":"","url":null,"abstract":"Psoriasis is a chronic inflammatory disease that can often accompany human immunodeficiency virus (HIV) epidemics. Development of psoriasis in HIV patients is correlated with a decrease in CD4+ count. Significant variability in the clinical presentation of psoriasis makes it a challenging disease to diagnose. Furthermore, associated immunodeficiency complicates standard treatment with immunosuppressive and biological therapy. Articles that match the terms psoriasis and HIV were searched in MEDLINE and Embase and selected based on their relevance. Highly active antiretroviral therapy (HAART) is a medication regimen used to manage and treat HIV infection. In treating mild psoriasis in HIV-positive patients, topical agents combined with HAART are considered first-line therapy, followed by phototherapy. Second-line therapy includes oral retinoids, alone or combined. In treating challenging cases, apremilast has been used due to its lack of immunosuppressive effect. In case of progressive and refractory disease, limited data from studies suggest that immunosuppressive or biological therapy may be effective. Treatment of psoriasis in HIV patients remains a challenge, which is largely attributable to its complicated etiopathology and lack of an approved therapy option. In treating severe psoriasis, close collaboration with an infectious disease specialist is highly recommended. Further research is needed, preferably with an aim toward developing individualized therapy.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"37-40"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Digging into uncertainty: a case report on Spitz lesions. 挖掘不确定因素：关于斯皮茨病变的病例报告。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Eva Klara Merzel Šabović, Dragan Jejinić, Andreja Pagon, Nina Jugovar, Violeta Hosta

引用次数: 0

Review of virological methods for laboratory diagnosis and characterization of monkeypox virus (MPXV): lessons learned from the 2022 Mpox outbreak. 猴痘病毒（MPXV）实验室诊断和定性的病毒学方法回顾：从 2022 年猴痘爆发中吸取的经验教训。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Marko Kolenc, Lucijan Skubic, Nataša Knap, Misa Korva, Mario Poljak, Tatjana Avšič-Županc

{"title":"Review of virological methods for laboratory diagnosis and characterization of monkeypox virus (MPXV): lessons learned from the 2022 Mpox outbreak.","authors":"Katarina Resman Rus, Samo Zakotnik, Martin Sagadin, Marko Kolenc, Lucijan Skubic, Nataša Knap, Misa Korva, Mario Poljak, Tatjana Avšič-Županc","doi":"","DOIUrl":"","url":null,"abstract":"Monkeypox virus (MPXV), originally endemic in West Africa (Clade II) and Central Africa (Clade I), has recently emerged worldwide and has reinforced the need for rapid and accurate MPXV diagnostics. This review presents and critically discusses the range of virological methods for laboratory diagnosis and characterization of MPXV as well as related lessons learned and practical experience gained from the 2022 Mpox global outbreak. Real-time PCR is currently considered the diagnostic gold standard and ensures accurate and timely confirmation of suspected Mpox cases based on suspicious skin lesions, and digital PCR improves the precision of MPXV DNA quantification. Whole genome sequencing reveals the diversity within the Clade IIb outbreak and highlights the role of microevolution in the adaptation of the virus to the human host. Continuous genomic surveillance is important for better understanding of human-to-human transmission and prevention of the emergence of variola virus-like strains. Traditional virological methods such as electron microscopy and virus isolation remain essential for comprehensive virus characterization, particularly in the context of vaccine and antiviral drug development. Despite the current challenges, serological tests detecting a range of anti-MPXV antibodies are important adjunct diagnostic and research tools for confirmation of late-presenting or asymptomatic MPXV cases, contact tracing, epidemiological studies, seroepidemiological surveys, and better understanding of the role of IgG and neutralizing antibodies in the immune response to infection and vaccination. A multidisciplinary approach combining advanced molecular techniques with traditional virological methods is important for rapid and reliable diagnosis, surveillance, and control of the outbreak.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"23-35"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 and oral lesions: 2020-2024 outpatient case series and literature review. COVID-19 与口腔病变：2020-2024 年门诊病例系列和文献综述。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Ana Glavina, Jozo Badrov, Marino Lukenda, Karmela Džaja, Dolores Biočina-Lukenda, Liborija Lugović-Mihić

{"title":"COVID-19 and oral lesions: 2020-2024 outpatient case series and literature review.","authors":"Ana Glavina, Jozo Badrov, Marino Lukenda, Karmela Džaja, Dolores Biočina-Lukenda, Liborija Lugović-Mihić","doi":"","DOIUrl":"","url":null,"abstract":"Data on oral lesions of coronavirus disease (COVID-19) are conflicting, and there are few evidence-based data on oral lesions directly caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this case series and literature review is to determine the prevalence of oral lesions associated with COVID-19 in outpatients and identify oral manifestations that are likely associated with COVID-19. We present 15 patients that came for their first specialist examination to the Oral Medicine Outpatient Clinic, Dental Clinic, Split, Croatia between November 2020 and January 2024. Their medical and dental history was taken following CARE guidelines. The prevalence of oral lesions associated with SARS-CoV-2 was 1.42% during the 4-year follow-up period. The most common oral lesions were nonspecific erosions, stomatitis, salivary flow disorders (xerostomia, oligosialia), salivary gland diseases (sialadenitis, chronic sialadenitis), candidiasis, pigmentation, aphthae, burning mouth syndrome, and geographic and fissured tongue. The mean latency period was 25.1 days. The site most commonly affected was the tongue (61.5%). Oral lesions associated with COVID-19 occurred in middle-aged patients, with an equal distribution by sex. They presented in a mild form and did not correlate with the severity of the clinical picture of COVID-19.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"41-48"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between sleep quality and chronotype differences and urticaria severity in patients with chronic spontaneous urticaria. 慢性自发性荨麻疹患者的睡眠质量和时间型差异与荨麻疹严重程度之间的关系。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Gulhan Gurel, Dilara Guler, Hasan Ali Guler, İrem Nur Durusu Türkoğlu, Isın Nur Sultan Oncu, Seçil Soylu

{"title":"The relationship between sleep quality and chronotype differences and urticaria severity in patients with chronic spontaneous urticaria.","authors":"Gulhan Gurel, Dilara Guler, Hasan Ali Guler, İrem Nur Durusu Türkoğlu, Isın Nur Sultan Oncu, Seçil Soylu","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Chronic spontaneous urticaria (CSU) is characterized by persistent or recurrent pruritic lesions that last more than 6 weeks. Patients with CSU may experience sleep disturbances, particularly due to itching. Biological rhythms (chronotypes) are categorized as morningness, intermediate, and eveningness types. This study evaluates the relationship between sleep quality, chronotype, and disease severity in CSU patients.Methods: The study included 53 CSU patients and 50 healthy controls. A sociodemographic data form was completed, and the disease severity was determined utilizing the Urticaria Activity Score over 7 days (UAS7). The Hospital Anxiety and Depression Scale (HADS), Insomnia Severity Index (ISI), and Pittsburgh Sleep Quality Index (PSQI) scales as well as the Morningness-Eveningness Scale (MEQ) were applied to the participants.Results: The CSU group had a significantly higher body mass index (BMI) than that of the healthy control group. In terms of sleep and chronotype scales, compared to the control group, the CSU group had higher ISI scores as well as subscale scores on the PSQI subscales, with the exception of habitual sleep efficiency and total PSQI scores. There was no difference between MEQ scores. In the correlation analysis, the UAS7 and PSQI total scores were found to be correlated, whereas in the logistic regression analysis the estimated relative risk of BMI and PSQI total score for CSU was found to be 1.13 and 1.45, respectively.Conclusions: When dealing with CSU patients, it is necessary to conduct a sleep quality assessment as part of a holistic evaluation.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"7-11"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Widespread dermatophytosis in a healthy adolescent: the first report of multidrug-resistant Trichophyton indotineae infection in the UAE. 一名健康青少年的大面积皮肤癣菌病：阿联酋首例耐多药毛癣菌感染病例。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Miloš D Pavlović, Shireen Marzouk, Leis Bećiri

引用次数: 0

Diagnostic accuracy of a short-form version of the diagnostic criteria for primary hyperhidrosis. 原发性多汗症诊断标准简表的诊断准确性。

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Mattias A S Henning, Hajer I Al-Rahimi, Gregor B E Jemec, Ole B Pedersen

{"title":"Diagnostic accuracy of a short-form version of the diagnostic criteria for primary hyperhidrosis.","authors":"Mattias A S Henning, Hajer I Al-Rahimi, Gregor B E Jemec, Ole B Pedersen","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The gold standard method for diagnosing primary hyperhidrosis (PHH) is based on seven patient-reported criteria. By determining an individual criterion's diagnostic accuracy, one can identify short-version classification models.Methods: In this cross-sectional study, data were collected from Danish blood donors in 2021. Cohen's kappa and diagnostic accuracy were determined by comparing each criterion with the gold standard method.Results: The study included 1,039 participants. Of them, 59 (5.7%) had PHH and 980 (94.3%) were classified as control individuals. The PHH major criterion \"focal visible excessive sweating for at least 6 months without an apparent cause\" had the highest prevalence in the participants with PHH compared to the control individuals (100% vs. 0.6%; p < 0.0001). The agreement between this criterion and PHH was Cohen's kappa = 0.95 (95% confidence interval [CI] 0.91-0.99), and its sensitivity was 1.00 (95% CI 0.94-1.00) and specificity 0.99 (95% CI 0.99-1.00). The other criteria showed lower agreement and diagnostic accuracy.Conclusions: The PHH major criterion showed near-perfect agreement and near-equal diagnostic accuracy compared with the gold standard method. This single criterion can be used as a short-form version to screen for PHH. Determination of reproducibility in independent populations is warranted.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"17-22"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hereditary angioedema: do patients have a specific "digital fingerprint" in Danish registries? 遗传性血管性水肿：丹麦登记册中的患者有特定的 "数字指纹 "吗？

IF 1.2

Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2024-03-01

Jakob Lillemoen Drivenes

{"title":"Hereditary angioedema: do patients have a specific \"digital fingerprint\" in Danish registries?","authors":"Jakob Lillemoen Drivenes","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Hereditary angioedema (HAE) is a potentially life-threatening genetic disorder characterized by recurrent episodes of angioedema. From the onset of symptoms until diagnosis, patients often have several contacts with the healthcare system. It was hypothesized that a \"digital fingerprint\" of undiagnosed HAE patients could be identified in Danish registries.Methods: This study compared patients with a control group of patients with a diagnosis of Quincke's edema (QE) or bee/wasp allergy because they could have phenotypic similarities.Results: QE was the most common diagnosis code in the hospital sector among HAE patients before a specific diagnosis of HAE was established. HAE patients had been seen at the hospital on average once every other year before the diagnosis was established, and on average once during the year before the diagnosis was established. Many patients contacted a practicing dermatologist during the year before the diagnosis was established.Conclusions: HAE patients had several hospital contacts due to swelling attacks during the years before their diagnosis was established, and half of them consulted a dermatologist. It was not possible to identify a specific \"digital fingerprint\" in Danish registries regarding specific procedures or diagnoses distinguishing them from the control group. It is therefore recommended that hospitalized patients with angioedema of unknown cause be screened for HAE.","PeriodicalId":45914,"journal":{"name":"Acta Dermatovenerologica Alpina Pannonica et Adriatica","volume":"33 1","pages":"13-16"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0