Journal of Oral Biosciences最新文献_第5页

Reduction in calcium responses to whisker stimulation in the primary somatosensory and motor cortices of the model mouse with trigeminal neuropathic pain 三叉神经痛模型小鼠初级躯体感觉皮层和运动皮层对胡须刺激的钙反应减少

IF 2.6

Journal of Oral Biosciences Pub Date : 2024-06-15 DOI: 10.1016/j.job.2024.06.003

{"title":"Reduction in calcium responses to whisker stimulation in the primary somatosensory and motor cortices of the model mouse with trigeminal neuropathic pain","authors":"","doi":"10.1016/j.job.2024.06.003","DOIUrl":"10.1016/j.job.2024.06.003","url":null,"abstract":"<div><h3>Objective</h3><p><span><span>Chronic constriction injury (CCI) of the </span>infraorbital nerve<span><span><span> induces neuropathic pain, such as </span>allodynia<span> and hyperalgesia, in the orofacial area. However, the changes in the local circuits of the </span></span>central nervous system following CCI remain unclear. This study aimed to identify the changes following CCI in Thy1-GCaMP6s </span></span>transgenic mice.</p></div><div><h3>Methods</h3><p><span><span>Neural activity in the primary somatosensory cortex (S1) and </span>motor cortex (M1) following whisker stimulation was assessed using in vivo Ca</span><sup>2+</sup> imaging. CCI-induced changes in responses were analyzed.</p></div><div><h3>Results</h3><p>Before CCI, whisker stimulation induced a greater Ca<sup>2+</sup><span> response in the contralateral S1 than in the ipsilateral S1 and contralateral M1. The peak Ca</span><sup>2+</sup> response amplitude in the bilateral S1 and contralateral M1 decreased two days after CCI compared to before CCI. Decreased Ca<sup>2+</sup> response amplitude in these regions was observed until four days after CCI. Seven days after CCI, the Ca<sup>2+</sup> response amplitude in the contralateral S1 decreased, whereas that in the ipsilateral S1 and contralateral M1 recovered to control levels.</p></div><div><h3>Conclusion</h3><p>These results suggest that neural activity in regions receiving excitatory inputs via corticocortical pathways recovers earlier than in regions receiving thalamocortical inputs. (185/250 words)</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 3","pages":"Pages 587-593"},"PeriodicalIF":2.6,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two-component regulatory system TCS08 of a serotype 4 strain in pneumococcal pneumonia pathogenesis 血清 4 型菌株的双组分调控系统 TCS08 在肺炎球菌肺炎发病机制中的作用。

IF 2.6

Journal of Oral Biosciences Pub Date : 2024-06-15 DOI: 10.1016/j.job.2024.06.001

{"title":"Two-component regulatory system TCS08 of a serotype 4 strain in pneumococcal pneumonia pathogenesis","authors":"","doi":"10.1016/j.job.2024.06.001","DOIUrl":"10.1016/j.job.2024.06.001","url":null,"abstract":"<div><h3>Objectives</h3><p><span><span>Streptococcus pneumoniae</span></span><span><span><span>, a human respiratory pathogen, causes diseases with severe morbidity and </span>mortality rates worldwide. The two-component regulatory system (TCS) is an important </span>signaling pathway<span> that enables regulation of gene expression in response to environmental cues, thereby allowing an organism to adapt to a variety of host niches. Here we examined the contribution of pneumococcal TCS08 to bacterial colonization, the development of pneumonia, and pulmonary dysfunction.</span></span></p></div><div><h3>Methods</h3><p>We employed an <em>hk08</em> knockout mutant (Δ<em>hk08</em><span>) with a background of the TIGR4 wild-type (WT) strain to verify whether TCS08 is associated with bacterial colonization and the development of pneumonia in a murine infection model. To clarify the association of </span><em>hk08</em> inactivation-induced phenotypic changes with their virulence, we examined pneumococcal capsule production, colony morphology, and surface-displayed protein profiles.</p></div><div><h3>Results</h3><p><span>Pneumococcal TCS08 was involved in bacterial colonization in the respiratory tract. Interruption of the signaling pathway of TCS08 by </span><em>hk08</em><span><span> inactivation impaired mouse survival and increased the bacterial burden within the respiratory tract. Furthermore, a histopathological examination revealed massive </span>inflammatory cell<span> infiltration, edema formation, and diffuse alveolar damage in the lung tissues of mice infected with Δ</span></span><em>hk08</em> versus the WT or complemented strain. Interestingly, virulence-associated phenotype changes, including capsule production, increased chain length, and surface-displayed protein profile, were observed in the Δ<em>hk08</em> strain.</p></div><div><h3>Conclusions</h3><p>The present findings indicate that TCS08 contributes to pneumococcal colonization and pulmonary dysfunction by assisting adaptation to the respiratory tract milieu, leading to the development of pneumonia.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 3","pages":"Pages 567-574"},"PeriodicalIF":2.6,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in the treatment of oral ulcerative mucositis from clinical and basic perspectives 从临床和基础角度看口腔溃疡性粘膜炎治疗的最新进展。

IF 2.6

Journal of Oral Biosciences Pub Date : 2024-06-10 DOI: 10.1016/j.job.2024.06.002

{"title":"Recent advances in the treatment of oral ulcerative mucositis from clinical and basic perspectives","authors":"","doi":"10.1016/j.job.2024.06.002","DOIUrl":"10.1016/j.job.2024.06.002","url":null,"abstract":"<div><h3>Background</h3><p>Oral ulcerative mucositis<span><span> (OUM) is common in patients with cancer, particularly in those undergoing chemoradiation therapy. The effective management of OUM is crucial for continuous cancer care and patient well-being. Recent studies have advanced our understanding of the causes, leading to </span>clinical trials toward novel treatments. This review focuses on the contemporary therapeutic landscape, and provides the latest insights into the mechanisms of mucosal healing and pain.</span></p></div><div><h3>Highlights</h3><p>Management strategies for OUM in patients with cancer include maintaining good oral hygiene<span><span>, reducing mucosal irritation against radiation, and using various topical analgesic<span><span> treatments, including herbal medicines. However, the current management practices have limitations that necessitate the development of more efficacious and novel treatments. Molecular research on transient receptor potential (TRP) channels in the oral mucosa is crucial for understanding the mechanisms of </span>wound healing<span> and pain in patients with OUM. Targeting TRPV3 and </span></span></span>TRPV4 can enhance wound healing through re-epithelialization. The suppression of TRPV1, TRPA1, and TRPV4 may be effective in alleviating OUM-induced pain.</span></p></div><div><h3>Conclusion</h3><p>Research advancements have improved our understanding and potentially led to novel treatments that offer symptomatic relief. This progress highlights the importance of collaborations between clinical researchers and scientists in the development of innovative therapies.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 3","pages":"Pages 504-510"},"PeriodicalIF":2.6,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141311970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “Nonsense-mediated mRNA decay affects hyperactive root formation in oculo-facio-cardio-dental syndrome via up-frameshift protein 1” [J Oral Biosci 66(1) March 2024 Pages 225–231] 更正："Nonsense-介导的 mRNA 衰变通过上帧移位蛋白 1 影响眼-面-心-牙综合征的牙根过度活跃形成" [J Oral Biosci 66(1) March 2024 Pages 225-231] （口腔生物科学杂志 66(1) March 2024 第 225-231 页

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2024.03.003

Ryoto Machida, Takuya Ogawa, Kyaw Min Soe, Keiji Moriyama

引用次数: 0

Inhibition of compound action potentials in the frog sciatic nerve by inchinkoto, a traditional Japanese medicine used for oral mucositis 用于治疗口腔黏膜炎的日本传统药物寸金藤对蛙坐骨神经复合动作电位的抑制。

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2024.03.001

Mayuko Nishimura , Suguru Taniguchi , Sachio Tamaoki , Tsugumi Fujita

{"title":"Inhibition of compound action potentials in the frog sciatic nerve by inchinkoto, a traditional Japanese medicine used for oral mucositis","authors":"Mayuko Nishimura , Suguru Taniguchi , Sachio Tamaoki , Tsugumi Fujita","doi":"10.1016/j.job.2024.03.001","DOIUrl":"10.1016/j.job.2024.03.001","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to determine the effects of traditional Japanese (Kampo) medicines used to treat oral mucositis on nerve conduction.</p></div><div><h3>Methods</h3><p>The effects of Kampo medicines, crude drugs, and chemical compounds on compound action potentials (CAPs) were analyzed using extracellular recordings in frog sciatic nerves.</p></div><div><h3>Results</h3><p>Among the Kampo medicines, inchinkoto demonstrated the most significant reduction in CAP amplitude, with a half-maximal inhibitory concentration (IC<sub>50</sub>) of 5.4 mg/mL. Hangeshashinto, shosaikoto, hochuekkito, and juzentaihoto also showed a significant reduction. Regarding inchinkoto, Artemisiae Capillari Spica (artemisia) was the most effective crude drug, with an IC<sub>50</sub> of 4.2 mg/mL for CAP amplitude reduction, whereas Gardeniae Fructus (gardenia) exerted no significant effect. However, the combined use of artemisia and gardenia reduced the CAP amplitude more effectively than artemisia alone, indicating a synergistic interaction. The chemical ingredient eugenol from artemisia administered at 1 and 3 mmol/L reduced CAP amplitude, whereas other chemical ingredients administered at 0.1 and 1 mmol/L had no significant effects.</p></div><div><h3>Conclusions</h3><p>Inchinkoto exhibited the most effective reduction in CAP amplitude in the sciatic nerve of frogs, primarily through the action of artemisia, with potential synergistic interaction between artemisia and gardenia.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 2","pages":"Pages 420-429"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic variations in exon 10 of ENAM and their association with early childhood caries ENAM第10外显子的基因变异及其与儿童早期龋齿的关系。

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2024.04.004

Aruna Sharma , M.S. Muthu , Vettriselvi V , Sivakumar Nuvvula , Gayathri T

{"title":"Genetic variations in exon 10 of ENAM and their association with early childhood caries","authors":"Aruna Sharma , M.S. Muthu , Vettriselvi V , Sivakumar Nuvvula , Gayathri T","doi":"10.1016/j.job.2024.04.004","DOIUrl":"10.1016/j.job.2024.04.004","url":null,"abstract":"<div><h3>Objective</h3><p>Enamelin is the largest enamel matrix protein encoded by the <em>ENAM</em> gene. The primary purpose of this study was to identify genetic variants in <em>ENAM</em> exon 10 that can alter susceptibility to early childhood caries (ECC).</p></div><div><h3>Methods</h3><p>This case-control study included 248 children aged 3–6 years, with 124 children diagnosed with ECC in the case group and 124 children without caries in the control group. Questionnaires were used to record demographic data, socioeconomic status, hygienic practices, and feeding practices, and a 24-h diet diary was kept. Seven polymorphisms (rs7671281, rs1738668322, rs3796703, rs3796704, rs759376039, rs775159311, and rs1738678483) in <em>ENAM</em> exon 10 were sequenced.</p></div><div><h3>Results</h3><p>The heterozygous CT genotype of rs7671281 was significantly more common in the case group compared to the control group (odds ratio [OR], 6.1765; 95% confidence interval [CI], 2.05–18.58; P = 0.0006). Under the dominant model, the TT genotype of rs7671281 was significantly more common in the control group (OR, 6.47; 95% CI, 2.15–19.39; P < 0.001). The AG genotype of rs3796704 was significantly more common in the case group than in the control group (OR, 5.705; 95% CI, 1.60–20.25; P = 0.006). Under the dominant model, the GG genotype of rs3796704 was significantly more common in children without caries than in children with caries (OR, 6.84; 95% CI, 1.96–23.90; P < 0.001).</p></div><div><h3>Conclusions</h3><p>The C allele of rs7671281 and the A allele of rs3796704 can increase susceptibility to ECC.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 2","pages":"Pages 349-357"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revolutionizing the diagnosis of irreversible pulpitis – Current strategies and future directions 彻底改变不可逆转性牙髓炎的诊断--当前策略和未来方向。

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2024.03.006

Raksha Bhat , Shishir Shetty , Praveen Rai , Ballamoole Krishna Kumar , Preethesh Shetty

{"title":"Revolutionizing the diagnosis of irreversible pulpitis – Current strategies and future directions","authors":"Raksha Bhat , Shishir Shetty , Praveen Rai , Ballamoole Krishna Kumar , Preethesh Shetty","doi":"10.1016/j.job.2024.03.006","DOIUrl":"10.1016/j.job.2024.03.006","url":null,"abstract":"<div><h3>Background</h3><p>Pulpitis primarily arises from the pulp space infection by oral microbiota. Vital pulp therapy is a minimally invasive approach that relies on assessing the severity of pulpal inflammation to facilitate repair. However, the current evaluation methods prescribed by the American Association of Endodontics are subjective, leading to ambiguity in assessment. Therefore, this review aims to explore molecular strategies for evaluating the severity of pulpal inflammation to accurately predict the success of pulp vitality preservation in clinical settings.</p></div><div><h3>Methodology</h3><p>This review was conducted by searching relevant keywords, such as irreversible pulpitis, pulpitis biomarkers, molecular diagnosis, inflammation, and genomic strategies, in databases such as PubMed, Web of Science, and Scopus to address the subjective nature of diagnosis. The data included in this review were collected up to April 2023. The literature search revealed well-documented limitations in clinically assessing the pulp inflammatory. Molecular approaches that aid in clinical differentiation between irreversible and reversible pulpitis may potentially enhance favorable outcomes in vital pulp therapy. Non-invasive diagnostic methods for pulpal assessment would also be valuable for determining whether the inflamed pulp is reversible, irreversible, or necrotic.</p></div><div><h3>Conclusion</h3><p>The present review examines the various molecular diagnostic approaches that have revolutionized the medical field and are considered the most promising empirical methodologies for the proactive detection of pulpal diseases. It also provides comprehensive insights into the current diagnostic methods, associated challenges, next-generation strategies, and future directions for diagnosing the severity of pulp inflammation.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 2","pages":"Pages 272-280"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Porphyromonas gingivalis infection alters microRNA composition in extracellular vesicles 牙龈卟啉单胞菌感染会改变细胞外囊泡中的 microRNA 组成。

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2024.04.001

Kayo Yoshida , Kaya Yoshida , Yasuhiro Mouri , Ayu Takai , Mariko Seyama , Mana Mekata , Noriko Mizusawa , Keiko Miyoshi , Yasusei Kudo , Kazumi Ozaki

{"title":"Porphyromonas gingivalis infection alters microRNA composition in extracellular vesicles","authors":"Kayo Yoshida , Kaya Yoshida , Yasuhiro Mouri , Ayu Takai , Mariko Seyama , Mana Mekata , Noriko Mizusawa , Keiko Miyoshi , Yasusei Kudo , Kazumi Ozaki","doi":"10.1016/j.job.2024.04.001","DOIUrl":"10.1016/j.job.2024.04.001","url":null,"abstract":"<div><h3>Objectives</h3><p>Periodontitis, commonly associated with <em>Porphyromonas gingivalis</em> (<em>Pg</em>), involves intricate alterations of oral intercellular interactions, in which extracellular vesicles (EVs) play a pivotal role. The understanding of the miRNA profiles in the EVs derived from <em>Pg</em>-infected cells (<em>Pg</em>-EVs) remains incomplete despite acknowledging their importance in intercellular communication during periodontitis. Therefore, our objective was to identify and characterize the miRNAs enriched in <em>Pg</em>-EVs.</p></div><div><h3>Methods</h3><p>Microarray analysis was conducted to examine the miRNA profiles in the EVs derived from <em>Pg</em>-infected THP-1 cells. We compared the identified miRNAs with those upregulated in the EVs after stimulation with LPS. Additionally, we explored how inhibiting TLR signaling during <em>Pg</em> infection affects the transcription of specific miRNAs. We investigated the unique sequence motifs specific to the miRNAs concentrated in <em>Pg</em>-EVs.</p></div><div><h3>Results</h3><p>The levels of eleven miRNAs, including miR-155, were increased in <em>Pg</em>-EVs compared with those elevated after LPS stimulation. The <em>Pg</em>-induced miR-155 upregulation via TLR2 but not TLR4 signaling suggests the influence of TLR signaling on the miRNA composition of EVs. Furthermore, the miRNAs upregulated in <em>Pg</em>-EVs contained AGAGGG and GRGGSGC sequence motifs.</p></div><div><h3>Conclusions</h3><p>Our findings demonstrate that <em>Pg</em>-induced alterations in EV-containing miRNA composition occur in a TLR4-independent manner. Notably, the concentrated miRNAs in <em>Pg</em>-EVs harbor specific motifs with a high G + C content within their sequences. The upregulation of specific miRNAs in EVs under infectious conditions suggests the influence of both innate immune receptor signals and miRNA sequence characteristics.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 2","pages":"Pages 365-372"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140764872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lactoferrin as a potential therapeutic for the treatment of Candida-associated denture stomatitis 乳铁蛋白是治疗念珠菌相关义齿口腔炎的一种潜在疗法。

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2024.05.007

Anna Maria Krupińska , Zdzisław Bogucki

引用次数: 0

Antibacterial activity of mulberry extracts and purified fractions against oral pathogenic bacteria 桑葚提取物和纯化馏分对口腔致病菌的抗菌活性。

IF 2.4

Journal of Oral Biosciences Pub Date : 2024-06-01 DOI: 10.1016/j.job.2023.12.009

Takahisa Shirai , Yutaroh Satoh , Kazuyuki Ishihara

{"title":"Antibacterial activity of mulberry extracts and purified fractions against oral pathogenic bacteria","authors":"Takahisa Shirai , Yutaroh Satoh , Kazuyuki Ishihara","doi":"10.1016/j.job.2023.12.009","DOIUrl":"10.1016/j.job.2023.12.009","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to isolate antibacterial compounds active against periodontopathic bacteria from mulberry (<em>Morus alba</em>) leaves.</p></div><div><h3>Methods</h3><p>The acetone-soluble fraction of mulberry leaves was extracted from the oil layer by oil/water separation. The extract was purified using silica gel open-column chromatography. The minimum inhibitory concentration (MIC) of the crude extract or purified fractions against <em>Porphyromonas gingivalis</em> was measured at each step.</p></div><div><h3>Results</h3><p>The MIC of the crude extract against <em>P. gingivalis</em> was 62.5–125 μg/mL. The fractions showing activity against <em>P. gingivalis</em> were designated Cf K and Cf P. The MICs of Cf K against <em>P. gingivalis</em>, <em>Fusobacterium nucleatum</em>, <em>Prevotella intermedia,</em> and <em>Streptococcus mutans</em> were 6.25 μg/mL, 25 μg/mL, 12.5 μg/mL, and 12.5 μg/mL, respectively. In contrast, the MICs of Cf P against <em>P. gingivalis</em>, <em>F. nucleatum</em>, <em>P. intermedia,</em> and <em>S. mutans</em> were 25.0 μg/mL, >50 μg/mL, 50 μg/mL, and 12.5–25.0 μg/mL, respectively.</p></div><div><h3>Conclusions</h3><p>Mulberry leaves contain antibacterial components against periodontopathic bacteria such as <em>P. gingivalis</em>, <em>F. nucleatum</em>, and <em>P. intermedia</em>.</p></div>","PeriodicalId":45851,"journal":{"name":"Journal of Oral Biosciences","volume":"66 2","pages":"Pages 439-446"},"PeriodicalIF":2.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0