Clinical, radiographic, and histological features of buccal bifurcation cysts: A systematic review to aid accurate diagnosis and treatment decisions

IF 2.3 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Oral Biosciences Pub Date : 2025-03-14 DOI:10.1016/j.job.2025.100652

Matheus de Castro Costa , Rani Kanthan , Marina Lara de Carli , Felipe Fornias Sperandio

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引用次数: 0

Abstract

Objective

This systematic review delves into the nuanced landscape of buccal bifurcation cysts (BBCs), emphasizing their clinical significance amid the diagnostic challenges in oral and maxillofacial pathology. We trace the evolution of BBC classification from historical perspectives to its current status in the World Health Organization's classification system, aiming to equip dental professionals with crucial insights for accurate diagnosis and effective management.

Methods

This systematic review (PROSPERO: CRD42023405169) followed PRISMA guidelines to examine the epidemiological characteristics of BBCs. Observational studies were included, while reviews, meta-analyses, and experimental studies were excluded. A comprehensive search across five databases identified eligible studies. Two independent reviewers screened articles, resolving disagreements by consensus or a third reviewer. Data extraction included clinical, histological, and imaging findings. Risk of bias was assessed using Murad's framework for case reports/series and the Newcastle–Ottawa Scale for other study types, with studies rated as low, moderate, or high quality.

Results

The information presented here is crucial for preventing past treatment errors associated with BBC. In addition, this review confirms that BBCs predominantly affect the posterior mandible of pediatric patients and exhibit consistent clinical and histopathological features, aiding in their differentiation from similar maxillofacial lesions. Thus, well-informed clinicians should be able to diagnose BBC and make a proper treatment choice after familiarizing themselves with this review, which will ultimately lead to a favorable prognostic outcome and reduced risk of lesion recurrence.

Conclusion

This study provides a comprehensive analysis of BBC, aiming to enhance clinical understanding and ultimately improve patient care.

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口腔分岔囊肿的临床、影像学和组织学特征：有助于准确诊断和治疗决策的系统综述。

目的：本系统综述深入探讨口腔分叉囊肿（BBCs）的细微特征，强调其在口腔颌面病理学诊断挑战中的临床意义。我们从历史的角度追溯BBC分类的演变，直到其在世界卫生组织分类系统中的现状，旨在为牙科专业人员提供准确诊断和有效管理的关键见解。方法：本系统评价（PROSPERO: CRD42023405169）遵循PRISMA指南，研究BBCs的流行病学特征。观察性研究被纳入，而综述、荟萃分析和实验研究被排除。在五个数据库中进行了全面的搜索，确定了符合条件的研究。两名独立审稿人对文章进行筛选，通过共识或第三方审稿人解决分歧。资料提取包括临床、组织学和影像学结果。使用Murad的病例报告/系列框架和纽卡斯尔-渥太华量表对其他研究类型进行偏倚风险评估，研究被评为低、中、高质量。结果：本文提供的信息对于预防过去与BBC相关的治疗错误至关重要。此外，本综述证实，BBCs主要影响儿童患者的后颌骨，并表现出一致的临床和组织病理学特征，有助于其与类似的颌面部病变区分开来。因此，知情的临床医生在熟悉本综述后，应该能够诊断出BBC，并做出适当的治疗选择，从而最终获得良好的预后，降低病变复发的风险。结论：本研究对BBC进行了全面的分析，旨在提高临床认识，最终改善患者护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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