Echo Research and Practice最新文献

{"title":"Significance of echocardiographic metrics including TRV and TAPSE/SPAP in mild haemodynamic pulmonary hypertension - data from EVIDENCE-PAH UK.","authors":"Nina Karia, Daniel Murphy, Luke Howard, Martin Johnson, David G Kiely, James Lordan, Colm McCabe, Joanna Pepke-Zaba, Daniel Knight, Vivek Muthurangu, J Gerry Coghlan","doi":"10.1186/s44156-026-00119-1","DOIUrl":"10.1186/s44156-026-00119-1","url":null,"abstract":"<p><strong>Background: </strong>The 2022 ESC/ERS guidelines redefined pulmonary hypertension (PH) as a mean pulmonary artery pressure (mPAP) >20 mmHg on right heart catheterisation (RHC). Echocardiography, using metrics such as tricuspid regurgitation velocity (TRV), tricuspid annular plane systolic excursion (TAPSE), and TAPSE/systolic pulmonary artery pressure (TAPSE/SPAP), guides referral for RHC. However, the few studies evaluating echocardiographic performance using the ESC/ERS 2022 thresholds have combined the newly included population as a relatively modest subgroup within their overall analysis.</p><p><strong>Results: </strong>We present a sample of 1,991 individuals from the EVIDENCE-PAH UK database. Our data demonstrate higher TRV and sPAP values and lower TAPSE/SPAP values with higher haemodynamic category. ROC analysis demonstrates that TRV, SPAP and TAPSE/SPAP perform well as predictors of mPAP > 20 mmHg and ≥25 mmHg (AUCs 0.785-0.830), but less well at predictive mPAP 21-24 mmHg (AUCs 0.656-0.686). In all PH patients and the mild PH (21-24 mmHg) subgroup, TAPSE/SPAP < 0.31 mm/mmHg predicted reduced survival (HR 2.01-3.14, p < 0.001). Similarly, in haemodynamically mild PH, TRV > 3.4 m/s was associated with worse survival compared to TRV < 2.5 m/s or 2.5-2.8 m/s (p < 0.001).</p><p><strong>Conclusions: </strong>While established echocardiographic metrics (TRV, TAPSE/SPAP) are strong predictors of significant PH (mPAP ≥25 mmHg), they are less accurate for mild PH (mPAP 21-24 mmHg). Importantly, mild PH itself is associated with increased mortality, and within this group, TRV >3.4 m/s and TAPSE/SPAP <0.31 mm/mmHg identify patients at highest risk, supporting their prognostic utility even in early haemodynamic disease.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of guideline definitions on right ventricular diameter in echocardiography: an automated analysis in controls and patients with pulmonary hypertension.","authors":"Frida N Hermansson, Bettia E Celestin, Shadi P Bagherzadeh, Gracia Fahed, Everton J Santana, Neha Mantri, Roham T Zamanian, Alison L Marsden, Seraina A Dual, Michael Salerno, Francois Haddad","doi":"10.1186/s44156-026-00118-2","DOIUrl":"10.1186/s44156-026-00118-2","url":null,"abstract":"<p><p>BACKGROUND: To improve standardization, the 2025 American Association of Echocardiography (ASE) guidelines revised the definitions of right ventricular (RV) basal and mid diameters, revising the 2010 ASE and European Society of Cardiology (ESC) definitions. OBJECTIVES: (1) To quantify differences in right ventricular (RV) diameter measurements between the 2010 and 2025 ASE guidelines, (2) to determine its impact on the diagnosis of RV enlargement (RVE), and (3) to compare these findings with a novel automated non-linear centerline-based approach. METHODS: We analyzed 208 healthy volunteers and 221 patients with pulmonary arterial hypertension (PAH). Using custom cardiac contour analysis (C2A) software, RV diameters were measured across three definitions. The 2010 ASE/ESC defines diameters as the maximal dimension in the basal and mid segments. In contrast, the 2025 ASE defines the basal diameter just below the tricuspid valve and the mid diameter at ~ 50% of RV inflow, both parallel to the annulus. The C2A method uses a non-linear RV centerline as a reference to standardize measurement locations: the mid-point is taken at 50% along the centerline, and the basal diameter is defined as the maximum perpendicular distance within the proximal third of the RV. We quantified nominal and relative definition differences and compared sex-specific RVE prevalence in healthy controls. Diagnostic performance (ROC) and outcome prediction (Cox models) are presented. RESULTS: The median age was 63 years in healthy volunteers (52% male) and 48 years in patients with PAH (22% male), with a median pulmonary vascular resistance index (PVRI) of 22 Wood units·m². Compared to ASE/ESC 2010 definitions, ASE 2025 diameters were 15% (basal) and 20% (mid) lower. Using the 2025 definition in healthy controls, basal RVE was observed in 1% of females and 22% of males, while mid-RVE was present in 6% of females and 35.8% of males. The 2010 definition showed slightly better discrimination for PAH (AUC 0.937 vs. 0.898, p < 0.001). However, the prediction of outcomes was similar between the two definitions, with C-statistics of 0.59 (0.53–0.65) and 0.59 (0.53–0.66), respectively. CONCLUSION: Differences in guideline definitions of RV diameters are important to consider when implementing them in clinical practice. </p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13244954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting changes in right ventricular systolic pressure: insights from Classification and Regression Tree (CART) analysis.","authors":"Shadi P Bagherzadeh, Kartik S Malunjkar, Neha M Mantri, Bettia E Celestin, Roham T Zamanian, Paul Heidenreich, Ingela Schnittger, Michael Salerno, David Oxborough, Daniel Augustine, Raymond Benza, Everton J Santana, Francois Haddad","doi":"10.1186/s44156-026-00120-8","DOIUrl":"10.1186/s44156-026-00120-8","url":null,"abstract":"<p><strong>Background: </strong>Right ventricular systolic pressure (RVSP) is an echocardiographic metric to monitor pulmonary hypertension (PH). However, there is no recommendation on what constitutes a meaningful change. In this study, we aimed to gain insight into how physicians at our institution report significant changes in RVSP. We then aimed to quantify the analytic variability of reported RVSP using duplicate analysis.</p><p><strong>Methods: </strong>We utilized the Stanford CardioShare Registry to identify 5,934 patients with 32,656 echocardiogram pairs with reported RVSP. Natural Language Processing was employed to categorize pairs into decrease, increase, no change, and no direct mention. Classification and Regression Tree (CART) analysis was applied to these groups to identify reporting thresholds among physicians. To assess the performance of the CART model, accuracy, precision, recall, and F1-score were reported using a stratified cross-validation method. In a separate cohort comprising 210 healthy volunteers and 208 patients with PH, two blinded core laboratory cardiologists measured the peak tricuspid regurgitation velocity. We employed a duplicate analysis method to model bias and a robust precision method for reporting RVSP and assessing analytical variability.</p><p><strong>Results: </strong>Of the total pairs of echocardiographic studies, RVSP was reported as stable in 48.9%, increased in 12.5%, decreased in 9.9% while 28.7% did not have a direct reference to RVSP change. CART analysis revealed that physicians most commonly determine change based on an absolute threshold of 8 mmHg and whether the change occurred within or outside the reference range. On cross-validation, the accuracy and F1-score were 83% and 79% for the increase and 81% and 74% for the decrease algorithms. In the duplicate analysis cohort, the analytic precision was 8-10% with worst relative precision at lower values of RVSP. This translates into a 15% reference change value, assuming a 4-5% biological variation.</p><p><strong>Conclusion: </strong>The study provides insights on real world practice of physician reporting in RVSP and provides directions for future recommendations regarding report changes.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13244848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of right ventricular free wall strain on current international echocardiography guidelines for the assessment of pulmonary hypertension.","authors":"C J B Wild, G Coghlan, A Charalampopoulos, A Hameed, J Suntharalingam, R Mackenzie Ross, D Knight, J Willis, J Page, A Gurung, M Johnson, N Karia, D Oxborough, O Peacock, D Thompson, D X Augustine","doi":"10.1186/s44156-026-00114-6","DOIUrl":"10.1186/s44156-026-00114-6","url":null,"abstract":"<p><strong>Background: </strong>Current guidelines define pulmonary hypertension (PH) as a mean pulmonary artery pressure (mPAP) >20mmHg at right heart catheterisation (RHC). International transthoracic echocardiography (TTE) PH guidelines recommend a multi-parameter assessment to estimate PH probability. Effectiveness of the inclusion of right ventricular free wall strain (RVFWS) has not been established using real world data.</p><p><strong>Study aims: </strong>To determine the accuracy of current European and American TTE PH guidance in detecting PH in patients attending a UK PH centre. The impact of addition of RVFWS to the efficacy of the European and American guidance was also evaluated.</p><p><strong>Methods: </strong>TTE with subsequent RHC (within 1.4 months) were undertaken in patients with suspicion of PH, referred for first time investigations. Echocardiographic variables were assessed in accordance with current European and American TTE guidance.</p><p><strong>Results: </strong>Of 549 patients assessed, 431 (79%) had RHC confirmed PH (average mPAP = 41mmHg). Sensitivity / specificity for detecting PH was calculated for the European Society of Cardiology (ESC) TTE PH recommendations (83% / 65% respectively); ESC + RVFWS (92% / 62% respectively); American Society of Echocardiography (ASE) TTE PH recommendations (89% / 49% respectively); ASE + RVFWS (96% / 36% respectively); TTE PASP > 35mmHg alone (75% / 73% respectively); TTE TRV > 2.8 m/s alone (77% / 78% respectively). Of those with RHC PH 3 (1%) subjects with a TRV > 2.8 m/s and 7 (3%) with a PASP > 35mmHg had no supporting signs of PH. Using TTE PASP > 35mmHg or TRV >2.8m/s with at least 2 abnormal TTE parameters (including RVFWS) gave similar sensitivity / specificity (74% / 79% vs 73% / 87% respectively). In those with RHC PH and TTE PASP >35mmHg or TRV >2.8m/s the significant majority had at least 2 TTE PH markers (99% & 97%). Whilst TTE PASP and RHC PASP correlation was good (r = 0.745), accuracy was poor with limits of agreements as high as 44mmHg (range = -29 to 44mmHg). In those with no measurable tricuspid regurgitation, 64% (n = 49) had RHC PH (11% of whole cohort); in those where TTE PASP <35mmHg 23% (n = 70) had RHC PH. In those felt to have an ESC PH low TTE probability 44% (n = 60) had RHC PH (14% of whole cohort). Incorporating RVFWS improved detection in those with a ESC low TTE PH probability, reducing false negatives by 43%.</p><p><strong>Conclusion: </strong>Current TTE PH algorithms lack sensitivity to detect patients with milder haemodynamic forms of PH. This can be improved with the addition of RVFWS.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13244624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148200411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agitated Saline Contrast Echocardiography in the diagnosis of right to left shunts: Guidance and recommendations from the British Society of Echocardiography.","authors":"Bushra Rana, Shaun Robinson, Liam Ring, Dave Oxborough, Mark Belham, Jim Newton, Alfa Ali, Nilesh Sutaria, Nina Bual, Martin Swaans, Nina Wunderlich, Victoria Delgado, David Northridge, Dave Hildick-Smith, Neil Ruparelia, Mark Turner, Michael Mullen, Chris Baker, Brian Clapp, Mark Spence, Horst Sievert, Iqbal Malik, Roxy Senior, Anjana Siva","doi":"10.1186/s44156-026-00117-3","DOIUrl":"10.1186/s44156-026-00117-3","url":null,"abstract":"<p><p>Contrast echocardiography encompasses two forms of ultrasound contrast agents. This article focuses on agitated saline (AS-C) contrast, commonly called 'bubble' contrast. Its main application is in identifying the presence of a right to left shunt in a number of clinical syndromes, often associated with a patent foramen ovale (PFO). Dependant on the clinical presentation, the presence of a PFO with a likelihood of a causal role may be considered for percutaneous PFO closure. This guideline outlines a structured approach to performing an AS-C transthoracic echocardiogram, including the indications, protocols, and potential pitfalls for performing AS-C transthoracic echocardiography (TTE). It also addresses when to proceed to more advanced imaging modalities and highlights clinical decision-making frameworks such as the RoPE score.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13224608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148139304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-density contrast echocardiography for patent foramen ovale assessment: sensitivity and relationship with invasively measured shunt severity and atrial septum morphology.","authors":"Karel Medilek, Tomas Ondrus, Tomas Mraz, Josef Bis, Jaroslav Dusek, Martin Poloczek, Martin Mates, Rudolf Praus, Marek Ballon, Juraj Hrecko, Josef Stasek","doi":"10.1186/s44156-026-00112-8","DOIUrl":"10.1186/s44156-026-00112-8","url":null,"abstract":"<p><strong>Background: </strong>Transthoracic contrast echocardiography (cTTE) is a first-line method for patent foramen ovale (PFO) assessment, but its sensitivity is reported as low and inconsistent. We aimed to investigate the sensitivity of high-density cTTE for PFO detection, and the relationship between left-heart contrast opacification grade, invasively measured shunt severity and atrial septum/PFO morphology.</p><p><strong>Methods: </strong>Fifty-five consecutive patients with proven PFO on contrast transoesophageal echocardiography (cTOE) underwent cTTE with high density contrast (colloid, mannitol) and invasive quantification of right-to-left shunt severity using the thermodilution method. Echocardiographic shunt severity was classified according to the degree of left atrial (cTOE) or left atrial/ventricular (cTTE) opacification as grade 0 (no bubbles), grade 1(mild), grade 2 (moderate) grade 3 (significant opacification).</p><p><strong>Results: </strong>For PFO detection, the sensitivity of rest + Valsalva cTOE was 100%. Compared with this reference, sensitivity of rest + Valsalva cTTE was 98.2%, Valsalva cTTE 97.7%, rest cTTE, 83.9% and rest cTOE, 77.3%. No significant association was observed between left-heart opacification grade on rest or Valsalva cTTE/cTOE and invasively measured right-to-left shunt severity categorized as < 10%, 10-19%, or ≥ 20% (p = 0.10-0.26). A moderate association only was identified between rest + Valsalva cTOE left atrium opacification grade and < 10% and ≥ 10% right-to-left shunt severity (p = 0.024, Cramér's coefficient = 0.368). No significant relationship was found between left-heart opacification grade and the presence of atrial septal aneurysm, Eustachian valve/Chiari's network, or PFO channel width and length (p = 0.45-0.77). Compared with rest cTOE, rest cTTE demonstrated equal contrast opacification grade in 56% and higher in 40%. Valsalva cTTE showed equal contrast opacification grade in 29% and higher in 46% of studies vs. Valsalva cTOE.</p><p><strong>Conclusions: </strong>In studies using high-density contrast, cTOE and cTTE with Valsalva, but not rest studies, are highly sensitive for PFO assessment. There is no clinically relevant relationship between the left-heart bubble opacification grade and invasively measured right-to-left shunt severity or atrial septum morphology. The left-heart contrast opacification grade is equal to or higher in cTTE than in cTOE, especially in rest studies.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13218023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148043910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strain characterization of multi-chamber cardiac dysfunction and associated prognosis in patients undergoing TAVR for severe AS.","authors":"Thomas Meredith, David Roy, Farhan Mohammed, Amy Pomeroy, Michael P Feneley, David W M Muller, Christopher Hayward, Mayooran Namasivayam","doi":"10.1186/s44156-026-00122-6","DOIUrl":"10.1186/s44156-026-00122-6","url":null,"abstract":"<p><strong>Background: </strong>In patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR), myocardial dysfunction may extend beyond the left ventricle and remain underrecognized by conventional severity classification paradigms. Strain echocardiography allows early detection of subclinical dysfunction across cardiac chambers, potentially enhancing prognostic stratification.</p><p><strong>Methods: </strong>We retrospectively analysed 234 patients with severe AS undergoing TAVR who had echocardiograms suitable for strain analysis. Left ventricular (LV), left atrial (LA), and right ventricular (RV) strain values were quantified pre- and post-TAVR. Chamber dysfunction was defined using consensus strain thresholds, and multichamber impairment (MCI) was defined by dysfunction in two or more chambers. A modified damage staging system incorporating strain data was compared to an established model. The association between chamber impairment and all-cause mortality was explored.</p><p><strong>Results: </strong>Strain-defined chamber impairment was common, with 29% of patients exhibiting MCI. LA dysfunction was the most frequent isolated abnormality, accounting for 88% of single chamber impairment. Modest improvement was observed post-TAVR, predominantly in LV global longitudinal strain (+ 1.8 ± 3.5%, p < 0.01). MCI was associated with higher rates of atrial fibrillation, chronic kidney disease, and mitral/tricuspid regurgitation. At 12-month follow-up, patients with three-chamber impairment had significantly increased mortality risk (HR 6.84, 95% CI 1.77-26.4, p = 0.005). The modified staging system reclassified 27% of patients into higher risk categories but did not significantly improve predictive accuracy over the established model.</p><p><strong>Conclusion: </strong>Multichamber dysfunction, particularly involving the LA, is prevalent in patients undergoing TAVR and confers a higher early mortality risk. While the addition of strain data improves damage detection, its incremental prognostic value over conventional models appears modest in this cohort. Larger studies are required to explore this further. Comprehensive strain imaging may nonetheless identify patients requiring closer surveillance and targeted post-TAVR therapy.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147844203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of contemporary echocardiography for the detection of cardiac sarcoidosis.","authors":"Joseph Okafor, Alessia Azzu, Raheel Ahmed, Kshama Wechalekar, Athol Wells, A John Baksi, Rakesh Sharma, Peter Collins, Nilesh Sutaria, Petros Nihoyannopolos, Roxy Senior, Vasileios Kouranos, Rajdeep S Khattar","doi":"10.1186/s44156-026-00111-9","DOIUrl":"10.1186/s44156-026-00111-9","url":null,"abstract":"<p><strong>Background: </strong>The ability of echocardiography (TTE) to diagnose cardiac sarcoidosis (CS) has traditionally been limited by its low sensitivity. We sought to determine the optimal TTE parameters to detect cardiac involvement in sarcoidos is with the inclusion of strain and 3DE to standard conventional TTE data.</p><p><strong>Methods: </strong>Consecutive patients referred for evaluation of suspected CS were prospectively recruited and underwent symptom evaluation, 12-lead ECG, ambulatory ECG monitoring, TTE with 3DE and strain, cardiac magnetic resonance and ¹⁸F-FDG-PET. We identified the TTE phenotype most likely to identify CS. We evaluated the ability of a novel multi-parametric approach to screen for cardiac involvement among sarcoidosis patients and compared this to existing criteria.</p><p><strong>Results: </strong>Of the 181 patients recruited (mean age 55 ± 11 years, 60% male, mean LVEF 57 ± 10%), 106 (59%) were diagnosed with CS. The strongest TTE parameters to predict CS were the presence of a dilated LV cavity (end-diastolic/end-systolic ≥ 71/28ml/m² females; ≥80/32ml/m² males), LVEF < 50%, RWMA involving multiple myocardial territories and basal septal thinning. This 'probable CS' TTE model had 96% specificity, 33% sensitivity and 92% PPV for the diagnosis of CS. The strain parameters most specific for a CS diagnosis were LVGLS and LVGCS greater than - 13% and - 15%, respectively. Adding strain or 3D data did not significantly improve the overall diagnostic ability of TTE. The optimal screening strategy for CS among sarcoidosis patients involved evaluation of symptoms, ECG or ambulatory ECG monitoring, and 'probable CS' TTE. This approach had a sensitivity of 90%, compared to 77% and 84% for the 2014 Heart Rhythm Society and 2020 American Thoracic Society criteria, respectively. In the asymptomatic patient, the absence of abnormal rhythm data and a normal TTE excluded CS in 94% of patients.</p><p><strong>Conclusion: </strong>The presence of LV dilatation, LV systolic impairment, multi-territory RWMA and basal septal thinning are the most specific TTE parameters for the detection of CS. In combination with symptom evaluation and ECG data, comprehensive echocardiography remains a useful screening tool among sarcoidosis patients with suspected cardiac involvement.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13112891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiography in cardio-oncology: optimising service delivery.","authors":"Joshua Lushington, Abhinav Kandala, Jose Bingcang, Ana Ferreira, Alex Byrne, Alex Sirker, Sanjeev Bhattacharyya, Jonathan Lambert, Victoria Grandage, Rachael Windsor, Robin Chung, Alison Macklin, J Malcolm Walker, Arjun K Ghosh","doi":"10.1186/s44156-026-00115-5","DOIUrl":"10.1186/s44156-026-00115-5","url":null,"abstract":"<p><p>Echocardiography plays a central role in the cardiovascular assessment and surveillance of patients with active cancer or in remission. With the development of specialised cardio-oncology services, the demand for echocardiography in cancer patients continues to grow. Here we explain the nuances of echocardiography in cardio-oncology, and detail how our institution has optimised service delivery to minimise cancer patient healthcare visits, improve time to cardio-toxicity diagnosis and utilising physiologists to lead cancer survivorship clinics.</p>","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13094049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts from the British Society of Echocardiography annual meeting 2025.","authors":"","doi":"10.1186/s44156-026-00108-4","DOIUrl":"10.1186/s44156-026-00108-4","url":null,"abstract":"","PeriodicalId":45749,"journal":{"name":"Echo Research and Practice","volume":"13 Suppl 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}