Integrated Pharmacy Research and Practice最新文献

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A Framework for Locating Prescribed Medication at Pharmacies. 在药店查找处方药的框架。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-01-01 DOI: 10.2147/IPRP.S415674
Matiwos Tekalign Wondmagegn, Evarist Nabaasa, Endashaw Amsalu Melesse, Ewunate Assaye Kassaw
{"title":"A Framework for Locating Prescribed Medication at Pharmacies.","authors":"Matiwos Tekalign Wondmagegn,&nbsp;Evarist Nabaasa,&nbsp;Endashaw Amsalu Melesse,&nbsp;Ewunate Assaye Kassaw","doi":"10.2147/IPRP.S415674","DOIUrl":"https://doi.org/10.2147/IPRP.S415674","url":null,"abstract":"<p><strong>Introduction: </strong>Accessibility of available medication at pharmacies is one of the core problems in the health sector of developing countries. The mechanism for optimally accessing the available drugs in pharmacies is unclear. Usually, patients in need are compelled to haphazardly switch between pharmacies in search of their prescription medications due to lack of information about the locations of pharmacies with required drug.</p><p><strong>Objective: </strong>The primary objective of this study is to develop a framework that will simplify the process of identifying and locating nearest pharmacy when searching for prescribed medications.</p><p><strong>Methods: </strong>Primary constraints (distance, drug cost, travel time, travel cost, opening and closing hours of pharmacies) in accessing required prescribed medications from pharmacies were identified from literature, and the client's and pharmacies' latitude and longitude coordinates were used to find the nearest pharmacies that have the required prescribed medication in stock.</p><p><strong>Results: </strong>The framework with web application was developed and tested on simulated patients and pharmacies and was successful in optimizing the identified constraints.</p><p><strong>Discussions: </strong>The framework will potentially reduce patient expenses and prevent delays in obtaining medication. It will also contribute for future pharmacy and e-Health information systems.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"127-136"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/f8/iprp-12-127.PMC10292612.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9726344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adherence to Good Pharmacy Practices by Community Pharmacies in Lebanon and Opportunities for Quality Improvement: It is Time to Act. 黎巴嫩社区药房遵守良好药房规范和提高质量的机会:是采取行动的时候了。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-01-01 DOI: 10.2147/IPRP.S377635
Alein Bou-Saba, Kassem M Kassak, Pascale Salameh
{"title":"Adherence to Good Pharmacy Practices by Community Pharmacies in Lebanon and Opportunities for Quality Improvement: It is Time to Act.","authors":"Alein Bou-Saba,&nbsp;Kassem M Kassak,&nbsp;Pascale Salameh","doi":"10.2147/IPRP.S377635","DOIUrl":"https://doi.org/10.2147/IPRP.S377635","url":null,"abstract":"<p><strong>Purpose: </strong>Good pharmacy practice is an important standard that highlight the quality of services in community pharmacies. In 2018, The Order of Pharmacists in Lebanon (OPL) published their own good pharmacy practices (GPP) guidelines. The need exists for investigational studies to assess GPP implementation status and the professional conduct of on-site staff towards these standards.</p><p><strong>Methods: </strong>Data collection was carried out between February and August 2020 using a questionnaire covering: Socio-demographic variables; Indicator A (Attitude of the Community Pharmacists); Indicator B (Services and Facilities); Indicator C (Dispensing); Indicator D (Storage). Data analysis were performed on SPSS version 25, <i>T</i>-Test and ANOVA were used. A significant p value of <0.001, 95% confidence interval and variables with missing data counting less than 10% were considered.</p><p><strong>Results: </strong>A total of 211 staffers from pharmacies were enrolled in the study, each representing one community pharmacy. The mean percent of adherence to GPP standards by community pharmacies in the South of Lebanon was below the recommended threshold of 75%. Only 65.09% adhered to all tested indicators (27% to Indicator A, 56.91% to Indicator B, 68.61% to Indicator C, 66.31% to Indicator D). Higher indicators were seen among providers who were aware of OPL standards (OR = 4.021), female (OR= 2.011) and being a licensed pharmacist (OR=3.506). Cronbach alpha of the overall score was 0.615.</p><p><strong>Conclusion: </strong>Further steps shall be taken to improve the compliance to GPP standards. Steps shall include, identification of the core standards, such as dispensing, provision of adequate information, monitoring of storage conditions, and ensuring the presence of a licensed pharmacist. It is highly recommended that the OPL and the Ministry of Public Health develop a \"Self-assessment tool\" and an efficient training program to increase community Pharmacists' awareness status. Regular assessment shall be carried to monitor the progress overtime.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"25-35"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/0c/iprp-12-25.PMC9888014.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10647014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceptions of Community Pharmacists Towards Patient Counseling and Continuing Pharmacy Education Programs in Sudan. 社区药剂师对苏丹患者咨询和继续药学教育项目的看法。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-01-01 DOI: 10.2147/IPRP.S406219
Riham M Hamadouk, Bashir A Yousef, Esra D Albashair, Fatimah M Mohammed, Ahmed H Arbab
{"title":"Perceptions of Community Pharmacists Towards Patient Counseling and Continuing Pharmacy Education Programs in Sudan.","authors":"Riham M Hamadouk,&nbsp;Bashir A Yousef,&nbsp;Esra D Albashair,&nbsp;Fatimah M Mohammed,&nbsp;Ahmed H Arbab","doi":"10.2147/IPRP.S406219","DOIUrl":"https://doi.org/10.2147/IPRP.S406219","url":null,"abstract":"<p><strong>Background: </strong>Community pharmacists are uniquely positioned at the heart of communities, and their patient counseling role is the cornerstone for achieving the required therapeutic goals. Therefore, the main objective of this study is to explore the perceptions of community pharmacists regarding patient counseling, and their perception towards continuing pharmacy education programs.</p><p><strong>Methods: </strong>A descriptive, cross-sectional design was performed among randomly selected 238 community pharmacies in Khartoum locality (Sudan) from September 2022 to December 2022. The data were collected using a self-administered questionnaire adopted from a previous study with few minor modifications, which was adding three sociodemographic questions. Descriptive statistics were carried out according to the study objective to analyze the pharmacists' responses.</p><p><strong>Results: </strong>The majority of the community pharmacists gave counseling and understood its importance to the patients, most of them (70.6%) took 1-5 minutes during the dispensing process. The dose was the most provided information by community pharmacists (26.7%) followed by administration (23.7%) and duration (22.4%). Few (28.2%) of the patients ask the pharmacists about the cost of the medication. Lack of patients' interest (55%) was the major barrier to effective counseling followed by lack of time (47.9%). Almost all (96.2%) pharmacists in this study were interested in continuing pharmacy education programs, and they preferred programs focusing on common diseases (36.6%), and common drugs (30.3%).</p><p><strong>Conclusion: </strong>This study showed that the majority of community pharmacists in the Khartoum locality had positive perceptions toward patient counseling and they were interested in continuing pharmacy education programs.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"77-85"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d5/e2/iprp-12-77.PMC10082612.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9284030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Pharmacist-Led Pharmaceutical Care Interventions Within Community Pharmacies: Narrative Review. 社区药房药剂师主导的药学服务干预的结果:叙述性回顾。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-01-01 DOI: 10.2147/IPRP.S408340
Ismaeil Eldooma, Maha Maatoug, Mirghani Yousif
{"title":"Outcomes of Pharmacist-Led Pharmaceutical Care Interventions Within Community Pharmacies: Narrative Review.","authors":"Ismaeil Eldooma,&nbsp;Maha Maatoug,&nbsp;Mirghani Yousif","doi":"10.2147/IPRP.S408340","DOIUrl":"https://doi.org/10.2147/IPRP.S408340","url":null,"abstract":"<p><p>Pharmaceutical care (PhC) services interventions led by pharmacists within community pharmacies (CPs) are essential in achieving optimal medication use outcomes. PhC is a concept related to medication use goals optimization through the reduction and prevention of drug-related problems (DRPs). This review paper summarized the literature on pharmacist-led PhC interventions within CPs. PubMed and Google Scholar publications were searched, identified, and summarized. Results showed that some studies handled community pharmacists' roles, and some talked about PhC interventions. However, some studies reviewed the use of medicines, adherence, and follow-up, while other groups were on counseling, patient education, and health promotion. Pharmacists integrated some studies concerning diagnosis and disease screening into community pharmacy services. Besides these studies, there were studies on system design and installation of PhC service models. Most of the identified research results showed pharmacist-led intervention benefits for patients. These benefits include reduced DRPs, clinical, economical, humane, education and knowledge, disease prevention and immunization, identification of practice process problems, and the need for current practice redesigning. In conclusion, pharmacists can help patients achieve optimal outcomes through pharmacist-led interventions. Despite mentioned results, We recommend researching comprehensively applied PhC services provision models within CPs for more pharmacists-led interventions and role activation.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"113-126"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/d1/iprp-12-113.PMC10198268.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9557905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Exploring Changes in Attitudes, Behaviors, and Self-Measured Health Data Through Lifestyle Modification Support by Community Pharmacists: Suito-Ogaki Selfcare (SOS) Trial. 通过社区药剂师的生活方式改变支持探索态度、行为和自我测量健康数据的变化:sui - ogaki自我护理(SOS)试验。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-01-01 DOI: 10.2147/IPRP.S408813
Yasushi Hibino, Shohei Matsumoto, Hisamitsu Nagase, Takamasa Nakamura, Yoshihito Kato, Tatsuya Isomura, Michiko Hori
{"title":"Exploring Changes in Attitudes, Behaviors, and Self-Measured Health Data Through Lifestyle Modification Support by Community Pharmacists: Suito-Ogaki Selfcare (SOS) Trial.","authors":"Yasushi Hibino,&nbsp;Shohei Matsumoto,&nbsp;Hisamitsu Nagase,&nbsp;Takamasa Nakamura,&nbsp;Yoshihito Kato,&nbsp;Tatsuya Isomura,&nbsp;Michiko Hori","doi":"10.2147/IPRP.S408813","DOIUrl":"https://doi.org/10.2147/IPRP.S408813","url":null,"abstract":"<p><strong>Purpose: </strong>Contributing to public health by supporting people's health is the social mission of community pharmacists. This multicenter, prospective case series study aimed to evaluate changes in people's behavior and health states through community pharmacists' self-care support for healthy lifestyles.</p><p><strong>Methods: </strong>The participants were recruited from voluntary adults aged ≥20 years who agreed to participate in the study, at community pharmacies in Gifu, Japan, between June and September 2021. Participants self-managed their lifestyles for six months while recording their health data, including blood pressure (BP), daily using devices (home BP monitor, body composition monitor, and activity meter) and a diet-recording app. They received lifestyle modification support at pharmacies at least once per month. Participants' subjective health status, attitudes, and behavioral changes were evaluated using self-report questionnaires. Due to the exploratory nature of this study, data were primarily analyzed descriptively.</p><p><strong>Results: </strong>Fifty-four participants aged 20 to 77 (mean age: 49.6 years; female participant proportion: 55.6%) participated in this study. Their mean weekly BP shifted almost horizontally from baseline to week 24 (systolic BP: 118.8 to 121.5 mmHg; diastolic BP: 76.1 to 77.5 mmHg). At six months, 38.9% and 35.2% of the participants reported better overall health and mental health, respectively, than at baseline. Over 85% of the participants became more proactive in improving their lifestyles regarding salt intake, diet, weight loss, and exercise, although drinking and smoking habits were more challenging to change. All the participants reported that they intended to continue to improve their lifestyle.</p><p><strong>Conclusion: </strong>The participants' responses suggested that community pharmacists' support helped increase participants' health awareness and promote their health-enhancing behaviors. However, its impact on health parameters should be further examined in future studies. More vigorous, tailored self-care support may be worth considering in developing a more effective, community-fitted health/well-being support system in Japan.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"87-99"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/30/c1/iprp-12-87.PMC10143748.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9763049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Community Pharmacists' Views on the Early Stages of Implementation of a National Pilot Independent Prescribing Service in Wales: A Qualitative Study. 社区药剂师对威尔士实施国家独立处方服务试点早期阶段的看法:一项定性研究。
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2023-01-01 DOI: 10.2147/IPRP.S395322
Efi Mantzourani, Rhian Deslandes, Karen Hodson, Andrew Evans, Lydia Taylor, Cherie Lucas
{"title":"Community Pharmacists' Views on the Early Stages of Implementation of a National Pilot Independent Prescribing Service in Wales: A Qualitative Study.","authors":"Efi Mantzourani,&nbsp;Rhian Deslandes,&nbsp;Karen Hodson,&nbsp;Andrew Evans,&nbsp;Lydia Taylor,&nbsp;Cherie Lucas","doi":"10.2147/IPRP.S395322","DOIUrl":"https://doi.org/10.2147/IPRP.S395322","url":null,"abstract":"<p><strong>Background: </strong>A pilot Independent Prescribers' Service (IPS) was introduced in 13 community pharmacies across Wales in June 2020. Independent Pharmacist Prescribers (IPPs) could prescribe in the areas of management of acute conditions, contraception, or opioid withdrawal, as agreed with local commissioners. Access to the patients' medical records was provided via <i>Choose Pharmacy</i>, the national community pharmacy IT platform.</p><p><strong>Objective: </strong>To explore the experiences of IPPs delivering the service and commissioners responsible for financial resources regarding the IPS in Wales.</p><p><strong>Methods: </strong>A qualitative methodology was employed, with purposive sampling, semi-structured interviews, and inductive thematic analysis.</p><p><strong>Results: </strong>Five themes were constructed from 13 interviews (n=9 IPPs; n=4 commissioners): (i) patient experience and safety; (ii) professional enablement and rebalancing workload of GPs; (iii) role and limitations of remote consultations; (iv) funding and business model; (v) functionality on <i>Choose Pharmacy</i> to support patient care. The design of the service allowed pharmacists to determine how best to deliver the IPS, maximizing access for patients and promoting a sense of professional value amongst pharmacists.</p><p><strong>Conclusion: </strong>This study builds on the body of evidence on enhanced patient experience with prescribing services in the community, reinforcing that IPPs have a key role in rebalancing management of common conditions from GP surgeries to community pharmacies. Several considerations need to be addressed to ensure future success of the service implementation, delivery and enhanced sustainability, such as formal referral pathways and access to medical records. These can be used by other commissioning bodies in the UK and internationally to build a network of suitably supported IPPs, confident to appropriately deal with uncomplicated acute and chronic conditions; and liaise with primary and/or secondary care when referrals are needed.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"12 ","pages":"11-23"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/f1/iprp-12-11.PMC9888007.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9213181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating Knowledge of Antibiotics, Antimicrobial Resistance and Antimicrobial Stewardship Concepts Among Final Year Undergraduate Pharmacy Students in Northern Nigeria. 调查尼日利亚北部药学专业最后一年本科生对抗生素、抗菌药耐药性和抗菌药管理概念的了解。
IF 2.1
Integrated Pharmacy Research and Practice Pub Date : 2022-12-23 eCollection Date: 2022-01-01 DOI: 10.2147/IPRP.S385692
Samirah N Abdu-Aguye, Kromdi G Barde, Hadiza Yusuf, Basira Kankia Lawal, Aishatu Shehu, Elijah Mohammed
{"title":"Investigating Knowledge of Antibiotics, Antimicrobial Resistance and Antimicrobial Stewardship Concepts Among Final Year Undergraduate Pharmacy Students in Northern Nigeria.","authors":"Samirah N Abdu-Aguye, Kromdi G Barde, Hadiza Yusuf, Basira Kankia Lawal, Aishatu Shehu, Elijah Mohammed","doi":"10.2147/IPRP.S385692","DOIUrl":"10.2147/IPRP.S385692","url":null,"abstract":"<p><strong>Introduction: </strong>Well trained, knowledgeable and competent pharmacists are indispensable in the fight against antimicrobial resistance (AMR), which is a current global public health problem. The aim of this work was to assess knowledge of antibiotics, antimicrobial resistance and antimicrobial stewardship of fifth year pharmacy students at three universities in Northern Nigeria.</p><p><strong>Methods: </strong>A descriptive cross-sectional study that used a paper-based questionnaire to collect data from July to September 2021 was conducted. The questionnaire was self-administered and divided into four sections. The first section collected information about the demographic data of respondents, while section B explored their knowledge of antibiotics and AMR. Section C contained six questions assessing knowledge of various aspects of antimicrobial stewardship (AMS), while the final part assessed respondents' preparedness to work with antibiotics and perceptions of their current knowledge of these concepts. Descriptive statistics were used to report the results obtained.</p><p><strong>Results: </strong>A total of 164 questionnaires were retrieved. Majority of respondents were male (58.3%) and aged between 21 and 25 years (53.4%). Most of them had some knowledge of antibiotics and AMR, however several misconceptions with respect to these concepts were identified. Only 80 (48.8%) of respondents indicated that they knew what AMS was, although most of these students were correctly knowledgeable about the goals and scope of AMS and composition of the AMS team. Generally, less than half of respondents agreed that their current knowledge of antibiotics, AMR or AMS was adequate for their future careers, and over 90% of them agreed that they would like more education about these topics.</p><p><strong>Conclusion: </strong>Many of the study's' respondents were somewhat knowledgeable about these concepts, although several knowledge gaps were also observed. Improving undergraduate pharmacy education with respect to these concepts is recommended.</p>","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"11 ","pages":"187-195"},"PeriodicalIF":2.1,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a3/cb/iprp-11-187.PMC9793721.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10446272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of HIV Rapid Test Kits Inventory Management Practice and Challenges in Public Health Facilities of Addis Ababa, Ethiopia [Corrigendum] 评估埃塞俄比亚亚的斯亚贝巴公共卫生设施的艾滋病毒快速检测试剂盒库存管理做法和挑战[勘误]
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2022-04-01 DOI: 10.2147/iprp.s369644
Azmeraw Bekele, Fenet Gemechu, Mihretu Ayalew
{"title":"Assessment of HIV Rapid Test Kits Inventory Management Practice and Challenges in Public Health Facilities of Addis Ababa, Ethiopia [Corrigendum]","authors":"Azmeraw Bekele, Fenet Gemechu, Mihretu Ayalew","doi":"10.2147/iprp.s369644","DOIUrl":"https://doi.org/10.2147/iprp.s369644","url":null,"abstract":"[This corrects the article DOI: 10.2147/IPRP.S356134.].","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"66 1","pages":"95 - 96"},"PeriodicalIF":2.9,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72486373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Potential Drug Interactions with AiDKlinik® in a Random Population Sample 随机人群样本中潜在药物与AiDKlinik®相互作用的评价
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2022-03-01 DOI: 10.2147/IPRP.S351938
J. Schmidberger, C. Kloth, Martin Müller, W. Kratzer, J. Klaus
{"title":"Evaluation of Potential Drug Interactions with AiDKlinik® in a Random Population Sample","authors":"J. Schmidberger, C. Kloth, Martin Müller, W. Kratzer, J. Klaus","doi":"10.2147/IPRP.S351938","DOIUrl":"https://doi.org/10.2147/IPRP.S351938","url":null,"abstract":"Purpose Undesirable drug interactions are frequent, they endanger the success of therapy, and they lead to adverse drug reactions. The present study aimed to evaluate statistically potentially drug interactions in a locally circumscribed, random sample population. Patients and Methods In a random sample population of 264 patients taking medications, we performed analyses with the drug information system AiDKlinik®. Statistical analysis was performed using SAS version 9.4. Results Statistically potentially drug interactions were recorded in 82/264 (31.1%) subjects, including 39/82 (47.56%) men, and 43/82 (52.43%) women (χ2= 0.081; p = 0.776). The average number of potential possible interactions detected per person was 1.60 ± 1.21. The regression model with the variables age, body-mass-index and number of long-term-medications shows a significant association between the number of long-term medications taken and the number of moderately severe and severe reactions to drug interactions (F(3.239) = 28.67, p < 0.0001; (t(239) 8.28; p < 0.0001)). After backward elimination, the regression model showed a significant interaction with the number of long-term medications (t (240) = 8.73, p < 0.0001) and body-mass-index (t (240) = 2.02, p = 0.0442). In descriptive analysis, the highest percentages of potential drug interactions occurred in 42/82 (51.22%) subjects with body mass indices (BMIs) >25 kg/m2 and in 28/82 (34.15%) subjects aged 61–70 years. Conclusion Number of long-term medications use, age, and obesity may lead to increased drug–drug interactions in a random population sample.","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"49 1","pages":"61 - 69"},"PeriodicalIF":2.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73404435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of HIV Rapid Test Kits Inventory Management Practice and Challenges in Public Health Facilities of Addis Ababa, Ethiopia 评估埃塞俄比亚亚的斯亚贝巴公共卫生设施的艾滋病毒快速检测试剂盒库存管理实践和挑战
IF 2.9
Integrated Pharmacy Research and Practice Pub Date : 2022-03-01 DOI: 10.2147/IPRP.S356134
Azmeraw Bekele, Fenet Gemechu, Mihretu Ayalew
{"title":"Assessment of HIV Rapid Test Kits Inventory Management Practice and Challenges in Public Health Facilities of Addis Ababa, Ethiopia","authors":"Azmeraw Bekele, Fenet Gemechu, Mihretu Ayalew","doi":"10.2147/IPRP.S356134","DOIUrl":"https://doi.org/10.2147/IPRP.S356134","url":null,"abstract":"Background Many people with undiagnosed HIV live in sub-Saharan Africa and vulnerable laboratory systems undermine testing services. Methods A facility-based mixed-approach cross-sectional study was conducted from January 1 to February 1, 2020. A total of 23 health facilities were included in the study which stratified into hospitals and health centers. Six months of bin card records and request and resupply forms (RRFs) were reviewed. Data were collected through physical inventory, observation, and document review. After the data was imported into the MS Excel 2016 spreadsheet, it was analyzed using SPSS | Version 20 | Software. In addition, 12 semi-structured in-depth interviews were conducted and responses were analysed using a thematic approach. Results The entire health facility had RRF reports and bin card records while the availability of HIV rapid test kits was 75%. More than half, 38 (55.1%) of the bin card records were updated and the average data accuracy of bin cards was 84.1%. The data quality of the RRF reports was determined accurate 18 (78.3%), complete 15 (65.22%), and on-time 7 (30.3%). Sixteen (69.6%) health facilities experienced at least one stock out with an average daily stock out of 4%. The wastage rate was 0.0083%. Only 9 (39.1%) health facilities have fulfilled acceptable storage conditions. Conclusion Most of the health facilities did no longer fulfilled acceptable storage conditions. Similarly, the data quality of most bin card records and RRF reports was poor. This deprived inventory management practice was likely related to supply, staff, and documentation challenges.","PeriodicalId":45655,"journal":{"name":"Integrated Pharmacy Research and Practice","volume":"17 1","pages":"85 - 94"},"PeriodicalIF":2.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83630946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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