Case Reports in Pathology最新文献

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Acute Myeloid Leukemia in a Cholecystectomy Specimen. 胆囊切除术标本中的急性髓性白血病。
IF 0.6
Case Reports in Pathology Pub Date : 2022-09-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2956052
Ana I Hernandez Caballero, Eduardo Castro-Echeverry, Roula Katerji, Christopher Gonzalez
{"title":"Acute Myeloid Leukemia in a Cholecystectomy Specimen.","authors":"Ana I Hernandez Caballero,&nbsp;Eduardo Castro-Echeverry,&nbsp;Roula Katerji,&nbsp;Christopher Gonzalez","doi":"10.1155/2022/2956052","DOIUrl":"https://doi.org/10.1155/2022/2956052","url":null,"abstract":"<p><p>A 76-year-old man was admitted into the ER for upper abdominal pain. Physical exam and CT scan confirmed acute cholecystitis with multiple cholelithis, and a cholecystectomy was performed. The cholecystectomy specimen showed chronic cholecystitis with exuberant inflammatory infiltrate. On careful examination of the specimen, large atypical cells with vesicular chromatin, folded nuclei, and inconspicuous red nucleoli were noted percolating into the gallbladder wall and lining vascular spaces. These cells were positive for CD117, CD43, and myeloperoxidase and negative for CD20 and CD3 stains. Further workup including peripheral blood flow cytometry confirmed a population of circulating immature myeloid precursors comprising about 38% of events. This is a rare case of acute myeloid leukemia that came to clinical attention by incidentally involving the gallbladder.</p>","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":" ","pages":"2956052"},"PeriodicalIF":0.6,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9529482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33489888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sclero-Hyalinized Low-Grade Appendiceal Mucinous Neoplasm Clinically Mimicking an Ovarian Mass. 临床表现与卵巢肿块相似的低级别阑尾硬透明粘液瘤。
IF 0.6
Case Reports in Pathology Pub Date : 2022-07-15 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9404615
Nnaemeka Thaddeus Onyishi, Anthony Jude Edeh, Ngozi Regina Dim
{"title":"Sclero-Hyalinized Low-Grade Appendiceal Mucinous Neoplasm Clinically Mimicking an Ovarian Mass.","authors":"Nnaemeka Thaddeus Onyishi,&nbsp;Anthony Jude Edeh,&nbsp;Ngozi Regina Dim","doi":"10.1155/2022/9404615","DOIUrl":"https://doi.org/10.1155/2022/9404615","url":null,"abstract":"<p><p>Low-grade appendiceal mucinous neoplasm is a tumor of the appendix whose major clinical relevance derives from its inherent potential for peritoneal dissemination as pseudomyxoma peritonei. It sometimes poses challenges in clinical, radiological, and pathological diagnosis, and it may be confused with gynecological conditions in females. We report a case of low-grade appendiceal mucinous neoplasm presenting as firm sclerotic cystic mass and was initially suspected to be an ovarian mass in a postmenopausal woman. We review the literature for the pathogenesis and clinical implication of sclerohyalinization in mucinous appendiceal tumors.</p>","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":" ","pages":"9404615"},"PeriodicalIF":0.6,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40549872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Epithelioid Hemangioendothelioma with WWTR1-CAMTA1 Fusion in the Parotid Gland Presenting as Bell's Palsy. 腮腺上皮样血管内皮瘤与WWTR1-CAMTA1融合表现为贝尔麻痹。
IF 0.6
Case Reports in Pathology Pub Date : 2022-06-24 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5687190
Landon J Kunzelman, Shweta Agarwal, Nathan Boyd, Cory J Broehm
{"title":"Epithelioid Hemangioendothelioma with <i>WWTR1-CAMTA1</i> Fusion in the Parotid Gland Presenting as Bell's Palsy.","authors":"Landon J Kunzelman,&nbsp;Shweta Agarwal,&nbsp;Nathan Boyd,&nbsp;Cory J Broehm","doi":"10.1155/2022/5687190","DOIUrl":"https://doi.org/10.1155/2022/5687190","url":null,"abstract":"<p><p>Epithelioid hemangioendothelioma is a rare tumor of endothelial differentiation most commonly arising in soft tissue, liver, and lung, following a variable clinical course. Most cases are characterized by a t(1;3)(p36;q23-25) resulting in <i>WWTR1-CAMTA1</i> fusion. Only five epithelioid hemangioendothelioma have been previously reported arising in the salivary glands. None have presented as Bell's palsy. In the current case, a 37-year-old female presented with a longstanding complaint of pain and fullness in the right preauricular region and progressive episodes of Bell's palsy and facial nerve weakness. Surgical resection showed a tumor comprised of atypical cells with occasional intracytoplasmic vacuoles in a fibromyxoid stroma. Immunohistochemical stains demonstrated the neoplastic cells expressed ERG, CD31, and CD34, confirming vascular differentiation. Fluorescence in situ hybridization revealed a t(1;3)(p36;q25), confirming a diagnosis of epithelioid hemangioendothelioma. At 12-month follow-up, the patient has no evidence of disease.</p>","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":" ","pages":"5687190"},"PeriodicalIF":0.6,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40468390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature. 双胎妊娠胎盘异位胎儿肝组织1例报告及文献复习。
IF 0.6
Case Reports in Pathology Pub Date : 2022-06-13 eCollection Date: 2022-01-01 DOI: 10.1155/2022/1966025
Andrei Leucă, Pieter Demetter, Amélie Boulay, Katherina Vanden Houte, Valérie Segers, Laurine Verset
{"title":"Ectopic Fetal Liver Tissue in the Placenta of a Twin Pregnancy: A Case Report and Review of Literature.","authors":"Andrei Leucă,&nbsp;Pieter Demetter,&nbsp;Amélie Boulay,&nbsp;Katherina Vanden Houte,&nbsp;Valérie Segers,&nbsp;Laurine Verset","doi":"10.1155/2022/1966025","DOIUrl":"https://doi.org/10.1155/2022/1966025","url":null,"abstract":"<p><p>Ectopic liver tissue represents a rare entity and is mostly attributed to events occurring during embryogenesis. Previous case reports documented the presence of fetal liver parenchyma within temporarily developed organs during pregnancy, such as the placenta or the umbilical cord. Moreover, the terminology of these benign findings varies from \"ectopic liver\" to \"hepatocellular adenoma-like neoplasm\" or \"hepatocellular adenoma\". Ancillary tests performed on these lesions have shown positive immunohistochemical staining for hepatocellular origin marker HepPar-1. Only one recent case report comprising molecular analysis showed no beta-catenin gain-of-function mutation. We report a case of ectopic liver in one placenta of a twin pregnancy, with an updated review of literature.</p>","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":" ","pages":"1966025"},"PeriodicalIF":0.6,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40223712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Consecutive Cervicovaginal Cytology Specimens Confirm Persistent Colonization by Cokeromyces recurvatus: Case Report and Literature Review 多个连续的宫颈阴道细胞学标本证实了复发角酵母的持续定植:病例报告和文献复习
IF 0.6
Case Reports in Pathology Pub Date : 2022-05-13 DOI: 10.1155/2022/2151926
Keng Lor, C. Hartley, B. Pritt, A. M. Kemp, Amy A. Swanson, C. Sturgis
{"title":"Multiple Consecutive Cervicovaginal Cytology Specimens Confirm Persistent Colonization by Cokeromyces recurvatus: Case Report and Literature Review","authors":"Keng Lor, C. Hartley, B. Pritt, A. M. Kemp, Amy A. Swanson, C. Sturgis","doi":"10.1155/2022/2151926","DOIUrl":"https://doi.org/10.1155/2022/2151926","url":null,"abstract":"The published literature on cervicovaginal cytology includes fewer than ten reported cases of Cokeromyces recurvatus identified in Pap test samples. We report a unique case of an asymptomatic 27-year-old female with persistent gynecologic tract colonization by C. recurvatus in which distinctive fungal microorganisms were identified in three samples collected over three consecutive years.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"2022 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89076890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intradural Extramedullary Concurrent Schwannoma and Meningothelial Hyperplasia at C2-C3 Cervical Vertebrae: A Case Report and Review of Literature C2-C3颈椎硬膜内髓外并发神经鞘瘤及脑膜上皮增生1例报告及文献复习
IF 0.6
Case Reports in Pathology Pub Date : 2022-05-05 DOI: 10.1155/2022/1087918
R. Rammal, Daniel F Marker, Rana Naous
{"title":"Intradural Extramedullary Concurrent Schwannoma and Meningothelial Hyperplasia at C2-C3 Cervical Vertebrae: A Case Report and Review of Literature","authors":"R. Rammal, Daniel F Marker, Rana Naous","doi":"10.1155/2022/1087918","DOIUrl":"https://doi.org/10.1155/2022/1087918","url":null,"abstract":"Concomitant schwannomas and benign meningothelial proliferations, including meningothelial hyperplasia or meningioma, rarely occur at the same location outside the setting of neurofibromatosis. Herein, we present a rare case of concurrent schwannoma and benign meningothelial hyperplasia concomitantly occurring in the cervical spine of a 69-year-old male patient with no history of any genetic disorder.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"39 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86154343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix 子宫颈胚胎性横纹肌肉瘤1例
IF 0.6
Case Reports in Pathology Pub Date : 2022-04-13 DOI: 10.1155/2022/8459566
Vishal Bahall, Lance De Barry, S. Sankar
{"title":"A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix","authors":"Vishal Bahall, Lance De Barry, S. Sankar","doi":"10.1155/2022/8459566","DOIUrl":"https://doi.org/10.1155/2022/8459566","url":null,"abstract":"Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is an exceedingly rare mesenchymal tumor that accounts for less than 1% of all cervical cancers. This highly malignant tumor primarily affects adolescents and young adults. Due to the paucity of publications on this clinical entity, there are no clearly established treatment protocols. However, a multimodal approach to treatment that involves surgical intervention combined with adjuvant chemoradiotherapy appears to improve patient outcomes. Herein, we report a case of embryonal rhabdomyosarcoma of the uterine cervix in a 24-year-old female, who presented with an exophytic cervical mass and vaginal bleeding. Histopathology and immunohistochemistry confirmed embryonal rhabdomyosarcoma of the uterine cervix with extension into the lower uterine segment. This patient was successfully managed with a combination of neoadjuvant chemoradiotherapy, a total abdominal hysterectomy with bilateral salpingo-oophorectomy, and adjuvant chemoradiotherapy.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"14 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72708575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
INI-1-Deficient Sinonasal Carcinoma: Case Report with Emphasis on Differential Diagnosis i -1缺失型鼻窦癌1例报告并强调鉴别诊断
IF 0.6
Case Reports in Pathology Pub Date : 2022-03-30 DOI: 10.1155/2022/5629984
Anwaar M. Alsayed, Eman Aljufairi, Amjad O. Alshammari, Khalid A Alsindi, Omar A Sabra
{"title":"INI-1-Deficient Sinonasal Carcinoma: Case Report with Emphasis on Differential Diagnosis","authors":"Anwaar M. Alsayed, Eman Aljufairi, Amjad O. Alshammari, Khalid A Alsindi, Omar A Sabra","doi":"10.1155/2022/5629984","DOIUrl":"https://doi.org/10.1155/2022/5629984","url":null,"abstract":"SMARCB1-deficient sinonasal carcinoma is a newly described entity, with less than 100 reported cases. It is characterized by basaloid or rhabdoid morphology and is diagnosed by complete loss of nuclear SMARCB1 (INI-1). The morphologic appearance, specific immunophenotypic markers, and unique molecular make-up distinguish this entity from other various malignant neoplasms. We present a case of a 55-year-old male that presented with a large progressing palatine mass. Magnetic resonance imaging showed a heterogeneous mass involving the left maxillary space. The initial biopsy was diagnosed as undifferentiated carcinoma. Resection was performed, and immunohistochemical studies revealed a complete loss of INI-1, refining the diagnosis to SMARCB1-deficient sinonasal carcinoma. Diagnosis of SMARCB1-deficient sinonasal carcinoma should be considered in all undifferentiated sinonasal carcinomas. Immunohistochemistry or molecular studies are mandatory to confirm the diagnosis and exclude other morphologically similar entities.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"25 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90115603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Deep Seated Lobular Capillary Hemangioma (Pyogenic Granuloma) of the Colon: A Rare Case Requiring Surgery beyond Endoscopic Management 结肠深层小叶毛细血管瘤(化脓性肉芽肿):一个罕见的病例需要手术超越内镜管理
IF 0.6
Case Reports in Pathology Pub Date : 2022-03-29 DOI: 10.1155/2022/5641608
Jae-Youn Park, Min-Jae Jung
{"title":"Deep Seated Lobular Capillary Hemangioma (Pyogenic Granuloma) of the Colon: A Rare Case Requiring Surgery beyond Endoscopic Management","authors":"Jae-Youn Park, Min-Jae Jung","doi":"10.1155/2022/5641608","DOIUrl":"https://doi.org/10.1155/2022/5641608","url":null,"abstract":"Background Lobular capillary hemangiomas typically present as skin or oral mucosa lesions and have rarely been described in unusual sites, including the gastrointestinal tract. Most colonic lobular capillary hemangiomas, either asymptomatic or associated with GI bleeding, have been amenable to endoscopic treatment in literatures. Case Presentation. A 41-year-old woman presented with an incidental colonic mass during a systemic workup after adjuvant chemotherapy for HER2-positive breast cancer. Abdominal computed tomography revealed a deep seated colonic mass in the splenic flexure. An endoscopic strip biopsy was attempted for differential diagnosis of this lesion, but uncontrolled bleeding occurred, and an emergency surgery was eventually performed. Microscopic examination showed lobular capillary hemangioma involving full thickness of the colonic wall with mucosal ulceration. Conclusions Colonic lobular capillary hemangioma is a benign vascular proliferation but is a candidate in differential diagnosis of benign or malignant tumors. Furthermore, the exceptional case may be deep seated and require more invasive surgery, unlike most cases of colonic lobular capillary hemangioma that can be treated with endoscopic modality.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"78 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88536764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents 术前应用生物制剂和免疫抑制剂治疗小肠结肠淋巴细胞性静脉炎
IF 0.6
Case Reports in Pathology Pub Date : 2022-03-07 DOI: 10.1155/2022/5120607
Soh Okano, T. Yao, Osamu Nomura, A. Nagahara, Toshiaki Hagiwara, Kiichi Sugimoto, Makoto Takahashi, K. Sakamoto
{"title":"Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents","authors":"Soh Okano, T. Yao, Osamu Nomura, A. Nagahara, Toshiaki Hagiwara, Kiichi Sugimoto, Makoto Takahashi, K. Sakamoto","doi":"10.1155/2022/5120607","DOIUrl":"https://doi.org/10.1155/2022/5120607","url":null,"abstract":"Enterocolic lymphocytic phlebitis is phlebitis of unknown etiology in which lymphocytes affect veins without arteries and shows evidence of systemic vasculitis in the intestinal wall and mesentery, mainly in the small intestine and colon. Although patients present with a variety of gastrointestinal symptoms and findings like those of inflammatory bowel disease or ischemic bowel disease, there are no specific findings for enterocolic lymphocytic phlebitis. As a result, a diagnosis tends to be made after surgery. There are few case reports of enterocolic lymphocytic phlebitis, and the impact of chronic courses and immunosuppressive drugs on enterocolic lymphocytic phlebitis is not well known. A 47-year-old man was treated with infliximab and steroids for unexplained ulceration and narrowing of the ileocecal area, which was suspected to be inflammatory bowel disease with atypical findings. Lymphocytic phlebitis was noted in the surgical specimen, and enterocolic lymphocytic phlebitis was diagnosed. No recurrence of enterocolic lymphocytic phlebitis was observed postoperatively. This disease should also be considered among patients with inflammatory bowel disease-like lesions that do not respond to infliximab or steroids.","PeriodicalId":45638,"journal":{"name":"Case Reports in Pathology","volume":"11 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88674970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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