子宫颈胚胎性横纹肌肉瘤1例

IF 0.7 Q4 PATHOLOGY
Vishal Bahall, Lance De Barry, S. Sankar
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引用次数: 5

摘要

子宫颈胚胎横纹肌肉瘤(RMS)是一种极为罕见的间充质肿瘤,占所有宫颈癌的不到1%。这种高度恶性肿瘤主要影响青少年和年轻人。由于缺乏关于这种临床实体的出版物,没有明确建立的治疗方案。然而,包括手术干预和辅助放化疗在内的多模式治疗方法似乎可以改善患者的预后。在此,我们报告一例24岁女性的子宫胚胎性横纹肌肉瘤,她表现为外生性宫颈肿块和阴道出血。组织病理学和免疫组织化学证实子宫子宫颈胚胎性横纹肌肉瘤,并延伸至子宫下段。该患者成功地接受了新辅助放化疗、全腹子宫切除术和双侧输卵管卵巢切除术以及辅助放化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is an exceedingly rare mesenchymal tumor that accounts for less than 1% of all cervical cancers. This highly malignant tumor primarily affects adolescents and young adults. Due to the paucity of publications on this clinical entity, there are no clearly established treatment protocols. However, a multimodal approach to treatment that involves surgical intervention combined with adjuvant chemoradiotherapy appears to improve patient outcomes. Herein, we report a case of embryonal rhabdomyosarcoma of the uterine cervix in a 24-year-old female, who presented with an exophytic cervical mass and vaginal bleeding. Histopathology and immunohistochemistry confirmed embryonal rhabdomyosarcoma of the uterine cervix with extension into the lower uterine segment. This patient was successfully managed with a combination of neoadjuvant chemoradiotherapy, a total abdominal hysterectomy with bilateral salpingo-oophorectomy, and adjuvant chemoradiotherapy.
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