{"title":"Pemphigus vulgaris and lichen planus pigmentosus in an HIV-positive patient.","authors":"Bushra Muna, Srikanth Shanmugam","doi":"10.4103/ijstd.ijstd_102_23","DOIUrl":"10.4103/ijstd.ijstd_102_23","url":null,"abstract":"<p><p>Pemphigus vulgaris is a rare autoimmune blistering disorder which can occur with other disorder with autoimmune etiology like lichen planus pigmentosus. The concurrence of pemphigus vulgaris and HIV infection has been rarely reported in literature. Here we report a 31 year old patient who came with oral and skin erosions suggestive of pemphigus vulgaris and later developed HIV infection with lichen planus pigmentosus.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"137-138"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kaposi's sarcoma unmasked by corticosteroids in an advanced HIV patient with tuberculosis immune reconstitution inflammatory syndrome.","authors":"Harshith B Kadnur, Haripriya Challa Reddy, Balasaheb Wanve, Rumapriya Sonowal, Hardik Rughwani, Anuradha Sekaran","doi":"10.4103/ijstd.ijstd_8_24","DOIUrl":"10.4103/ijstd.ijstd_8_24","url":null,"abstract":"<p><p>In this case report, we present a 35-year-old homosexual man with advanced HIV disease and disseminated tuberculosis (TB) who developed paradoxical TB immune reconstitution inflammatory syndrome (IRIS). Corticosteroids, vital in life-threatening IRIS, were initiated, resulting in symptom resolution but unmasking AIDS-associated Kaposi's sarcoma (KS). Diagnostic confirmation revealed disseminated KS, necessitating a comprehensive therapeutic strategy involving chemotherapy and thalidomide as a steroid-sparing agent. This case underscores the complexity of managing advanced HIV disease with IRIS, emphasizing the cautious use of corticosteroids due to the potential risk of KS unmasking. The report contributes to the limited documentation of indigenous HIV-associated KS cases in India and highlights the need for vigilant monitoring and careful therapeutic decisions in this population.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"141-143"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Posterior uveitis of syphilitic etiology.","authors":"Murugan Sankaranantham","doi":"10.4103/ijstd.ijstd_65_23","DOIUrl":"10.4103/ijstd.ijstd_65_23","url":null,"abstract":"<p><p>Uveitis in syphilis was reported often though it is not common. It can occur both in early and late syphilis. Syphilis transmission through anal contact and heterosexual contact is common. Transmission through oral sex in the absence of extragenital lesions is extremely rare. If not diagnosed earlier, uveitis can damage the vision permanently. The eyes will not see what the mind does not know. Hence, this case was reported to alert the young physicians to recognize this condition earlier. A high index of suspicion is essential to arrive at the diagnosis of this condition. Ocular syphilis and late syphilitic manifestations are quite rare nowadays. Once again, a resurge in syphilis cases was observed widely all over the globe and also in India. At this juncture, it will not be a surprise to have once again a rising incidence of cerebral venous system and central nervous system syphilis. Young physicians would not have a chance to come across a case of a case of ophthalmic syphilis. The report of such cases will alert them and make them suspect and diagnose cases of ocular syphilis earlier so that we can overcome the chances of preventable blindness with effective treatment.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"120-121"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niharika Dhattarwal, Prakhar Srivastava, Prashant Verma, Sumathi Muralidhar, Niti Khunger
{"title":"The first \"confirmed\" case of lymphogranuloma venereum at Apex Regional STD Centre in North India in the last two decades: Importance of specimens from multiple sites.","authors":"Niharika Dhattarwal, Prakhar Srivastava, Prashant Verma, Sumathi Muralidhar, Niti Khunger","doi":"10.4103/ijstd.ijstd_61_24","DOIUrl":"10.4103/ijstd.ijstd_61_24","url":null,"abstract":"","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"169-170"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling epilepsia partialis continua as an early indicator of HIV encephalitis.","authors":"Balakrishnan Arivalagan, Jitesh Goel, Salil Gupta, Bhanu Pratap Singh, Srishti Bhardwaj, Karthik Rayapureddi","doi":"10.4103/ijstd.ijstd_56_24","DOIUrl":"10.4103/ijstd.ijstd_56_24","url":null,"abstract":"<p><p>A young male with no known addictions and comorbidities presenting with recurrent clonic-myoclonic movements, initially localized to the left corner of the mouth and left upper limb, evolving into epilepsia partialis continua, despite appropriate sequential antiepileptic medications, subsequently progressed to refractory status epilepticus. He was tested positive for HIV infection and his neuroimaging revealed nonenhancing lesions, a novel finding in HIV-related encephalitis. We managed him with intravenous immunoglobulin along with multiple antiepileptic medications and highly active antiretroviral therapy (ART), and he exhibited a rapid clinical recovery over 3 weeks. This case highlights the importance of initiating immunomodulatory therapy promptly at presentation and underscores the challenges of managing drug interactions between antiepileptic drugs and antiretroviral therapy (ART), emphasizing the need for careful selection of medications in HIV-infected individuals.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"159-162"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pregnancy-associated <i>de novo</i> systemic lupus erythematosus in people living with HIV/AIDS.","authors":"Vibhu Mendiratta, Anukriti Yadav","doi":"10.4103/ijstd.ijstd_100_23","DOIUrl":"10.4103/ijstd.ijstd_100_23","url":null,"abstract":"<p><p>Pregnancy with systemic lupus erythematosus (SLE) requires special attention in view of the enhanced risks to the fetus and the aggravation of SLE during pregnancy. Human immunodeficiency virus infection can further complicate the course of pregnancy as well as the outcome. We present a case of a 28-year-old primigravida who was diagnosed case of people living with HIV/AIDS and presented with SLE at 34 weeks of gestation. Subsequent evaluation of the patient revealed latent tuberculosis also. Cutaneous lesions responded well to oral corticosteroids, however, the outcome of pregnancy was hydrops fetalis. This report highlights the complex interplay of multiple comorbidities and their adverse impact on pregnancy outcome.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"121-125"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Behcet syndrome: A rare cause of recurrent genital ulceration.","authors":"Sanya Kamal Narang, Hiral A Shah","doi":"10.4103/ijstd.ijstd_92_24","DOIUrl":"10.4103/ijstd.ijstd_92_24","url":null,"abstract":"<p><p>Behcet syndrome (BS) is a chronic relapsing multisystem vasculitis with skin findings with an important contribution of genetics. Here, we present a case of a 16-year-old male with a complaint of recurrent genital, and oral ulceration with skin lesions and a history of recurrent thrombophlebitis at the sites of venepuncture. There were no systemic manifestations. Pathergy test and HLA-B51 were negative. The diagnosis was confirmed based on the International Criteria for Behcet disease (ICBD) for BS. Tapering doses of systemic corticosteroid and colchicine showed promising response and regression of lesions.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"156-159"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relapse of secondary syphilis in a PLHIV - A new entity.","authors":"Murugan Sankaranantham","doi":"10.4103/ijstd.ijstd_24_24","DOIUrl":"10.4103/ijstd.ijstd_24_24","url":null,"abstract":"<p><p>Syphilis and other bacterial sexually transmitted infections (STIs) are on the verge of resurge throughout the world. Coinfection of syphilis and HIV is quite common as they both share a common mode of transmission. The behavior of syphilis is quite altered in the presence of HIV. Relapse of secondary syphilis after the recommended treatment is quite unusual. One such case has been reported, and possible pathogenesis was discussed.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"147-149"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kaposi's sarcoma immune reconstitution inflammatory syndrome: A forgotten entity nowadays.","authors":"Fernández Romero Cristina, Vila Cobreros Lorena, Fenollosa Sanz Tamara, Flores Cid Juan, Valero Núñez Marta, Puglia Santos Víctor Carlos, Galeano Paniagua Laura Andrea, Carmena Ramón Rafael, Quecedo Estébanez Esther","doi":"10.4103/ijstd.ijstd_57_24","DOIUrl":"10.4103/ijstd.ijstd_57_24","url":null,"abstract":"<p><p>The appearance of antiviral therapy has led to a change in the prognosis and clinical manifestations of patients with human immunodeficiency virus infections and Kaposi's sarcoma. However, there are still countries in which access is inadequate and the disease progresses toward disseminated forms with an unfavorable outcome. We present two patients who presented with skin lesions that progressed for a month, compatible with disseminated Kaposi's sarcoma in the context of HIV. One month after starting treatment, they were admitted for multi-organ failure associated with an Immune reconstitution inflammatory syndrome and eventually died.</p>","PeriodicalId":44880,"journal":{"name":"Indian Journal of Sexually Transmitted Diseases and AIDS","volume":"45 2","pages":"151-154"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}