Fukushima Journal of Medical Science最新文献_第3页

Successful treatment of anti-signal recognition particle antibody-positive myositis with intravenous cyclophosphamide: A case report. 静脉注射环磷酰胺成功治疗抗信号识别颗粒抗体阳性肌炎1例。

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Fukushima Journal of Medical Science Pub Date : 2025-01-18 Epub Date: 2024-12-07 DOI: 10.5387/fms.24-00013

Jumpei Temmoku, Shuhei Yoshida, Kanae Tsuchihashi, Yuya Sumichika, Kenji Saito, Haruki Matsumoto, Yuya Fujita, Naoki Matsuoka, Tomoyuki Asano, Nozomu Matsuda, Shuzo Sato, Kiyoshi Migita

引用次数: 0

2024 Fukushima Medical University International Symposium on the Fukushima Health Management Survey -3.11: Sharing Lessons of Fukushima with Japan and the World. 2024福岛医科大学福岛健康管理调查国际研讨会-3.11：与日本和世界分享福岛经验。

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Fukushima Journal of Medical Science Pub Date : 2025-01-18 Epub Date: 2024-12-07 DOI: 10.5387/fms.24-00058

Rie Mizuki, Seiji Yasumura

引用次数: 0

Histological outcome evaluation of selected brain preparation protocols for white fiber dissection. 对选定的白纤维解剖脑制备方案进行组织学结果评估。

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Fukushima Journal of Medical Science Pub Date : 2024-10-18 Epub Date: 2024-10-04 DOI: 10.5387/fms.23-00016

Masayuki Yamada, Kenichiro Iwami, Mudathir Bakhit, Masahiro Okamoto, Kiyoshi Saito, Masazumi Fujii

{"title":"Histological outcome evaluation of selected brain preparation protocols for white fiber dissection.","authors":"Masayuki Yamada, Kenichiro Iwami, Mudathir Bakhit, Masahiro Okamoto, Kiyoshi Saito, Masazumi Fujii","doi":"10.5387/fms.23-00016","DOIUrl":"10.5387/fms.23-00016","url":null,"abstract":"Background: White fiber dissection is essential for studying brain connections.　However, preparation protocols have not been validated.Methods: We microstructurally analyzed Klingler's brain preparation method and freezing process and assessed changes under two protocols:freeze-only and freeze-thaw.　The microstructure changes of these protocols were evaluated by measuring the ratio of the total gap area to the white matter area and determining the mean eccentricity value to assess the degree of anisotropy.Results: Sixty hemispheres were allocated to ten different freezing protocols.　In the freeze-only protocols, the total gap area ratio was significantly higher compared to that of specimens fixed with only formaldehyde, particularly after continuous freezing for 3-4 weeks;however, the difference in eccentricity was not significant.　In the freeze-thaw protocols, both the area ratio and eccentricity were significantly higher compared to the freeze-only.　The optimum degree of fiber separation in the freeze-thaw protocols reached its peak with four cycles of 1-week freezing periods interrupted by six hours of thawing.Conclusion: The Klingler method assists in the separation of the white fibers through the gaps formed by ice crystals, but an appropriate degree of anisotropy is reached when the freezing protocol is interrupted by at least four thawing cycles.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"203-209"},"PeriodicalIF":0.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The utility of MRI for the preoperative differential diagnosis of uterine sarcoma and leiomyoma: a single-center study. 核磁共振成像在子宫肉瘤和子宫肌瘤术前鉴别诊断中的应用：一项单中心研究。

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Fukushima Journal of Medical Science Pub Date : 2024-10-18 Epub Date: 2024-10-04 DOI: 10.5387/fms.23-00018

Hiroyuki Yazawa, Riho Yazawa, Kazuki Anjo, Akari Inazuki, Manabu Kikuta

{"title":"The utility of MRI for the preoperative differential diagnosis of uterine sarcoma and leiomyoma: a single-center study.","authors":"Hiroyuki Yazawa, Riho Yazawa, Kazuki Anjo, Akari Inazuki, Manabu Kikuta","doi":"10.5387/fms.23-00018","DOIUrl":"10.5387/fms.23-00018","url":null,"abstract":"Although uterine sarcoma is a rare disease, its prognosis is extremely poor;thus, it is important to differentiate it from uterine leiomyoma.　In this retrospective study, we examined the association between preoperative MRI findings and postoperative pathology results in 170 patients with uterine tumors who underwent preoperative MRI examination at Fukushima Red Cross Hospital.　In 4 cases of sarcoma / smooth muscle tumor of unknown malignant potential (STUMP), abnormal findings were found at a high frequency with T1-weighted imaging (T1WI) (75%), T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and contrast enhancement (CE) (100%).　In cases of ordinary leiomyoma, on the other hand, abnormal findings were less frequent.　The rates of high DWI signal intensity for degenerated and cellular leiomyoma were 31% and 64%, respectively, and the CE-positive rates were 31% and 57%, respectively.　Apparent Diffusion Coefficient (ADC) values appeared to be useful in differentiating degenerated leiomyoma from sarcoma.　The relatively characteristic findings of uterine sarcoma on MRI images may overlap with those of degenerated leiomyoma and cellular leiomyoma, making it difficult to diagnose sarcoma on imaging alone.　However, findings that distinguish sarcoma from ordinary, degenerated, and cellular leiomyoma cases are worthy of attention, to avoid overlooking sarcoma.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"211-218"},"PeriodicalIF":0.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Remote Orthotic Fabrication Method Using Small Three-Dimensional Printers and Computed Tomography Data: A Technical Report. 使用小型三维打印机和计算机断层扫描数据的远程矫形器制作方法：技术报告。

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Fukushima Journal of Medical Science Pub Date : 2024-10-18 Epub Date: 2024-10-04 DOI: 10.5387/fms.23-00015

Takeru Yokota, Takuya Nikaido, Masanori Abe, Yoshihiro Kikuchi, Shinichi Konno, Miho Sekiguchi, Takuya Kameda, Yojiro Takahashi, Katsuhiro Yoshida, Yasufumi Sekiguchi, Yoshihiro Matsumoto

{"title":"Remote Orthotic Fabrication Method Using Small Three-Dimensional Printers and Computed Tomography Data: A Technical Report.","authors":"Takeru Yokota, Takuya Nikaido, Masanori Abe, Yoshihiro Kikuchi, Shinichi Konno, Miho Sekiguchi, Takuya Kameda, Yojiro Takahashi, Katsuhiro Yoshida, Yasufumi Sekiguchi, Yoshihiro Matsumoto","doi":"10.5387/fms.23-00015","DOIUrl":"10.5387/fms.23-00015","url":null,"abstract":"Introduction: Computer-aided design and manufacturing (CAD/CAM) methods have gained prominence in early orthotic provision.　This study introduces an innovative approach using compact three-dimensional (3D) printers and computed tomography data to generate segmented body models for traditional Damen corset orthoses.　The goals included evaluating the comfort and fit of orthoses and assessing the effectiveness of our approach for prosthetic companies with limited financial resources.Materials and methods: Lumbar and thoracolumbar orthoses were crafted via CAD/CAM.　Four healthy patients wore the orthoses, with whom immediate and 1-week comfort and fit assessments were conducted.　A prosthetist assessed fit, and the Japanese edition of OPUS-CSD, the Orthotics Prosthetics Users' Survey-Client Satisfaction with Device, was used for subjective assessment of comfort and fit.Results: The fit evaluations were satisfactory for all patients with positive predefined criteria.　Questionnaire responses confirmed high satisfaction and comfort, confirming a successful orthosis fit.Conclusion: We established an orthotic fabrication method using CAD/CAM methods with 3D printers.　Additionally, we confirmed the comfort and fit of the corsets so produced.　The initial cost of 3D printers is lower than that of traditional carving machines, enabling even small-scale orthotic fabrication facilities to utilize CAD/CAM methods.　Further research and refinements of this manufacturing approach are expected to expand its applicability.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"193-201"},"PeriodicalIF":0.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seven cases illustrating difficulties in the treatment of MPO-ANCA-positive refractory otitis media. 七个病例说明 MPO-ANCA 阳性难治性中耳炎的治疗难题。

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Fukushima Journal of Medical Science Pub Date : 2024-10-18 Epub Date: 2024-10-04 DOI: 10.5387/fms.2023-21

Koshi Otsuki, Mitsuyoshi Imaizumi, Shigeyuki Murono

{"title":"Seven cases illustrating difficulties in the treatment of MPO-ANCA-positive refractory otitis media.","authors":"Koshi Otsuki, Mitsuyoshi Imaizumi, Shigeyuki Murono","doi":"10.5387/fms.2023-21","DOIUrl":"10.5387/fms.2023-21","url":null,"abstract":"There are increasing reports of patients with refractory otitis media caused by anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), especially myeloperoxidase (MPO)-ANCA-positive middle ear disease.　However, making a definitive diagnosis can be difficult, which can adversely affect the outcome of treatment.　We reviewed the diagnostic features of MPO-ANCA-positive middle ear disease and here discuss the difficulties of timely diagnosis and treatment.　Seven cases were eligible (6 women, 1 man;aged 57-83 years), and all were MPO-ANCA positive and proteinase 3 (PR3)-ANCA negative.　The patients were referred to our institution for management of intractable otitis media (2/7), progressive hearing loss (7/7) with facial palsy (1/7), and/or a high MPO-ANCA titer (5/7).　All patients underwent tapering steroid therapy and their MPO-ANCA titer was monitored.　Refractory MPO-ANCA-positive otitis media was noted:5 of 7 cases showed improvement with tapering steroid therapy but cure was not achieved in the remaining 2 cases.　This study demonstrates the difficulties in the diagnosis and treatment of localized AAV.　Early diagnosis and treatment can improve the prognosis of patients with AAV but global diagnostic criteria for ear disease have not been established.　Additional cases should be prospectively examined to establish a treatment for MPO-ANCA-positive middle ear disease.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"175-182"},"PeriodicalIF":0.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of attitudes toward schizophrenia among medical students and health professionals in Japan and their associated factorsamong medical students: a cross-sectional study. 日本医学生和卫生专业人员对精神分裂症的态度及其相关因素的比较：一项横断面研究。

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Fukushima Journal of Medical Science Pub Date : 2024-10-18 Epub Date: 2024-10-04 DOI: 10.5387/fms.23-00012

Mariko Kataoka, Tetsuya Ohira, Satoshi Tsuboi, Itaru Miura, Hirooki Yabe

{"title":"Comparison of attitudes toward schizophrenia among medical students and health professionals in Japan and their associated factorsamong medical students: a cross-sectional study.","authors":"Mariko Kataoka, Tetsuya Ohira, Satoshi Tsuboi, Itaru Miura, Hirooki Yabe","doi":"10.5387/fms.23-00012","DOIUrl":"10.5387/fms.23-00012","url":null,"abstract":"Changing perceptions of schizophrenia is crucial for both medical professionals and students.　This study examined negative attitudes toward schizophrenia among medical students, psychiatrists, psychiatric staff, physicians, and non-medical workers.　We created an 18-item survey using a web-based tool to assess attitudes toward schizophrenia, focusing on three factors:stigma, underestimation of patients' abilities, and skepticism about treatment.　To compare scores among the five participants' groups, we used analysis of covariance, adjusting for age and sex.　The study included 237 medical students, 10 psychiatrists, 16 psychiatric staff, 26 physicians, and 98 non-medical workers.　After adjusting for age and sex, the overall discrimination score for psychiatrists was significantly lower than those of medical students, physicians, and non-medical workers.　Among medical students, a comparison of each score by grade revealed that underestimation of patients' abilities scores was significantly higher in the fourth year than in the third year.　Furthermore, those aspiring to become psychiatrists had significantly lower adjusted mean and stigma scores than students with different career goals (p<0.05).　In conclusion, medical students, as well as physicians and non-medical workers, displayed higher levels of stigma towards schizophrenia than psychiatrists.　It is essential to explore modifying factors to improve medical students' attitudes towards schizophrenia.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"219-228"},"PeriodicalIF":0.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subjective Difficulty with Higher-Level Functional Capacity in Community-Dwelling Older People withMild Cognitive Impairment. 在社区居住的轻度认知障碍老年人对高级功能能力的主观困难。

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Fukushima Journal of Medical Science Pub Date : 2024-10-18 Epub Date: 2024-10-04 DOI: 10.5387/fms.23-00013

Yoshitaka Shiba, Saori Anzai, Takuya Ueda, Naoki Sasa, Tetsuya Yamagami, Yoshitsugu Omori

{"title":"Subjective Difficulty with Higher-Level Functional Capacity in Community-Dwelling Older People withMild Cognitive Impairment.","authors":"Yoshitaka Shiba, Saori Anzai, Takuya Ueda, Naoki Sasa, Tetsuya Yamagami, Yoshitsugu Omori","doi":"10.5387/fms.23-00013","DOIUrl":"10.5387/fms.23-00013","url":null,"abstract":"Background and purpose: Mild cognitive impairment (MCI) is a predictor of future age-related dementia.　We herein investigated associations of MCI with higher-level functional capacities, as well as with subjective difficulty regarding these functions, in community-dwelling older people, to identify a simple method for early MCI detection.Method: We administered a test battery to 118 community-dwelling older people living in an urban area.　The battery consisted of three tests;the Tokyo Metropolitan Institute of Gerontology Index of Competence (TMIG-IC), the Touch Panel-type Dementia Assessment Scale (TDAS), and the Geriatric Depression Scale-15.　We then excluded participants with possible dementia or depression symptoms, and divided the remainder (n = 67) into an MCI group (n = 16) and a non-MCI group (n = 51), according to TDAS performance.Results: Logistic regression analysis with the MCI and non-MCI groups as dependent variables indicated that TMIG-IC was a significant variable.　Male sex and the perception that preparing meals and filling out pension forms had become more difficult were significantly associated with MCI, each independently increasing the probability of MCI.Conclusions: Subjective difficulty with higher-level functions and impairment in higher-level functional capacity may serve as indices for mass screening for MCI.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"183-192"},"PeriodicalIF":0.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11625852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palliative care practices and their relationship to training: A cross-sectional study of community-oriented physicians. 姑息关怀实践及其与培训的关系：以社区为导向的医生横断面研究。

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Fukushima Journal of Medical Science Pub Date : 2024-07-24 Epub Date: 2024-07-19 DOI: 10.5387/fms.23-00007

Kuniko Kodama, Satoshi Kanke, Ryuki Kassai

{"title":"Palliative care practices and their relationship to training: A cross-sectional study of community-oriented physicians.","authors":"Kuniko Kodama, Satoshi Kanke, Ryuki Kassai","doi":"10.5387/fms.23-00007","DOIUrl":"10.5387/fms.23-00007","url":null,"abstract":"Objectives: This study aimed to investigate the training methods family physicians (FPs) use to enhance their professional development in palliative care. We also determined the relationship between these methods and palliative care practice.Methods: A questionnaire survey was administered to 557 FPs. Palliative care practices were measured using the palliative care self-reported practices scale (PCPS;range 1-5), and associations among the eight indicators of FP palliative care training were considered. Quantile regression analysis was used for the analysis.Results: Valid responses were received from 307 FPs:99.4% of the FPs provided palliative care and home visits, and 92.8% received palliative care training. The PCPS score was higher in participants who reported having received palliative care training (adjusted coefficient, 0.4 [95% CI, 0.12-0.68]; P=0.004). The palliative care training method was found to be significantly associated with the PCPS score \"Self-study through literature\" (adjusted coefficient 0.18 [95% CI, 0.01-0.34]; P=0.03) and \"Reflection on the practices\" (adjusted coefficient 0.24 [95% CI, 0.08-0.4]; P=0.004).Conclusions: FPs actively provided palliative care in their communities and used various palliative care training methods for professional development. \"Reflection on the practices\" and \"Self-study through literature\" were important elements of community-based palliative care practice.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"141-151"},"PeriodicalIF":0.7,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Four cases of isolated fallopian tube torsion successfully treated with laparoscopic surgery:A case series. 腹腔镜手术成功治疗四例孤立性输卵管扭转：病例系列。

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Fukushima Journal of Medical Science Pub Date : 2024-07-24 Epub Date: 2024-06-26 DOI: 10.5387/fms.23-00021

Riho Yazawa, Hiroyuki Yazawa, Kazuki Anjyo, Akari Inazuki

{"title":"Four cases of isolated fallopian tube torsion successfully treated with laparoscopic surgery:A case series.","authors":"Riho Yazawa, Hiroyuki Yazawa, Kazuki Anjyo, Akari Inazuki","doi":"10.5387/fms.23-00021","DOIUrl":"10.5387/fms.23-00021","url":null,"abstract":"We report four cases of isolated fallopian tube torsion (IFTT) successfully treated with laparoscopic surgery over the past 10 years. Two young women (each 19 years old) were IFTT with paraovarian cyst (POC) and tubal preservation was possible with detorsion and cystectomy. The other two patients (a 41-year-old woman with hydrosalpinx and a 50-year-old woman with hematosalpinx) underwent salpingectomy and adnexectomy, respectively, because there was no desire for tubal preservation. One patient had emergency surgery due to severe abdominal pain, one had semi-emergency surgery due to mild abdominal pain, and the other two were diagnosed during scheduled surgery without symptoms.Although IFTT was considered a very rare disease, our case series and recent reports suggest that it may have been underestimated, as it accounts for approximately 10% of adnexal torsion cases. Preoperative diagnosis of IFTT may be more difficult than for adnexal torsion because of its infrequency and nonspecific, vague clinical symptoms.　Since the prevalent age for this disease is young, as in our first 2 patients, early surgical intervention to preserve the fallopian tubes should be chosen when necessary, and it seems to be important for gynecologists to be aware of this disease for earlier diagnosis and appropriate surgical intervention.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"163-168"},"PeriodicalIF":0.7,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0