Fukushima Journal of Medical Science最新文献

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Structural associations between self-perception of support and knowledge of disability characteristics of autism spectrum disorder among staff in facilities providing after-school day services. 提供课后日间服务机构的员工对自闭症谱系障碍残疾特征的自我支持感和知识之间的结构性关联。
IF 0.7
Fukushima Journal of Medical Science Pub Date : 2024-07-24 Epub Date: 2024-07-13 DOI: 10.5387/fms.23-00010
Yoshinobu Tanaka, Shigeki Kurasawa, Kazuo Ouchi, Naoyuki Oi
{"title":"Structural associations between self-perception of support and knowledge of disability characteristics of autism spectrum disorder among staff in facilities providing after-school day services.","authors":"Yoshinobu Tanaka, Shigeki Kurasawa, Kazuo Ouchi, Naoyuki Oi","doi":"10.5387/fms.23-00010","DOIUrl":"10.5387/fms.23-00010","url":null,"abstract":"<p><strong>Background: </strong>We constructed a hypothetical model of the knowledge of autism spectrum disorder (ASD) and self-perception of support of staff working in after-school day services to clarify structural relationships.</p><p><strong>Methods: </strong>A questionnaire survey was conducted at 194 facilities providing after-school day services in Fukushima Prefecture (October 2020), including a basic attributes questionnaire, the Literacy Scale of Characteristics of Autistic Spectrum Disorder (LS-ASD), and a staff questionnaire. We developed a hypothetical model of the relationship between self-perception and LS-ASD total scores of after-school service staff. To obtain latent variables for structural equation modeling (SEM) to confirm factor extraction and the interrelationships among variables, exploratory factor analysis was performed. SEM was used to examine the fit of the hypothetical model to the data and the relationships among variables.</p><p><strong>Results: </strong>The study included 302 staff members from 58 of 194 facilities. Four factors (Factor 1, motivation; 2, self-perception of knowledge; 3, information sharing; 4, self-confidence) were extracted. The final model showed that Factor 2 had a positive direct effect (path coefficient = 0.64) and Factor 4 had a negative direct effect (path coefficient = -0.22) on LS-ASD scores. The model goodness of fit was acceptable (Goodness-of-Fit Index = 0.890; Comparative Fit Index = 0.912; Root Mean Square Error of Approximation = 0.086; Akaike's Information Criterion = 392.7).</p><p><strong>Conclusion: </strong>Self-perception of knowledge contributes greatly to knowledge acquisition, while excessive confidence may hinder knowledge retention.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"153-162"},"PeriodicalIF":0.7,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydropic leiomyoma-like ovarian tumor: a case report. 水瘤样卵巢肿瘤:病例报告。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-04-26 Epub Date: 2024-03-15 DOI: 10.5387/fms.2023-22
Tomoko Yamaguchi, Hyo Kyozuka, Yoshihiro Kochi, Fumihiro Ito, Hajime Odajima, Daisuke Suzuki, Yasuhisa Nomura
{"title":"Hydropic leiomyoma-like ovarian tumor: a case report.","authors":"Tomoko Yamaguchi, Hyo Kyozuka, Yoshihiro Kochi, Fumihiro Ito, Hajime Odajima, Daisuke Suzuki, Yasuhisa Nomura","doi":"10.5387/fms.2023-22","DOIUrl":"10.5387/fms.2023-22","url":null,"abstract":"<p><p>Uterine leiomyomas, benign tumors common in reproductive-aged women, can display rare variants such as hydropic leiomyoma (HL), which exhibit unique histological features like zonal edema and increased vascularity. However, due to its rarity, comprehensive clinical knowledge about HL is limited. We report a case of a 49-year-old Japanese woman who was premenopausal and nulliparous, presenting with a two-year history of abdominal distension. An MRI scan revealed a 20 cm mass in the posterior part of the uterus, exhibiting characteristics suggestive of an ovarian tumor. During laparotomy, a cystic tumor connected with a swollen fibroid was found, and pathology confirmed HL. This case emphasizes that hydropic leiomyomas can mimic malignant tumors on ultrasonography due to their atypical features, necessitating additional evaluations using alternative imaging techniques or histopathological examinations for accurate diagnosis and appropriate management. The patient recovered uneventfully, broadening our understanding of HL's clinical presentation.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"93-98"},"PeriodicalIF":0.8,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of walking speed and plantar pressure after chopart amputation. 髋关节截肢后行走速度和足底压力的调查。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-04-26 Epub Date: 2024-03-15 DOI: 10.5387/fms.23-00003
Kazuo Ouchi, Mari Sato, Yuki Kashiwabara, Mutsumi Shimazaki, Shoji Yabuki
{"title":"Investigation of walking speed and plantar pressure after chopart amputation.","authors":"Kazuo Ouchi, Mari Sato, Yuki Kashiwabara, Mutsumi Shimazaki, Shoji Yabuki","doi":"10.5387/fms.23-00003","DOIUrl":"10.5387/fms.23-00003","url":null,"abstract":"<p><strong>Background: </strong>In foot amputation, Chopart amputation is considered to have a high risk of deformity, and can result in poor function. We experienced a case in which Chopart amputation combined with tendon transfer and tendon lengthening was performed, and the patient was eventually able to walk independently with a foot prosthesis without experiencing deformity of the foot. We investigated walking speed and plantar pressure after Chopart amputation with and without a foot prosthesis.</p><p><strong>Case: </strong>A 78-year-old man underwent Chopart amputation with tendon transfer and tendon lengthening. As a result, he was able to stand up and walk, both while bearing weight on the heel of the affected foot, but he was unable to push off the ground using that foot. When a foot prosthesis was introduced, the patient's walking speed increased from 0.6 m/s without the prosthesis to 0.8 m/s with the prosthesis, which was an increase of 33%. The plantar pressure at the stump decreased from 129.3 N/cm<sup>2</sup> on average without the prosthesis to 51.6 N/cm<sup>2</sup> with the prosthesis, which was a 59% decrease. Wearing a foot prosthesis improved the patient's walking speed and decreased plantar pressure at the amputation stump.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"99-102"},"PeriodicalIF":0.8,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of testicular stiffness in boys with unilateral cryptorchidism after orchiopexy by ultrasound strain elastography. 通过超声应变弹性成像评估单侧隐睾男童睾丸切除术后的睾丸硬度。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-04-26 Epub Date: 2024-03-09 DOI: 10.5387/fms.2023-19
Yuichi Sato, Yusuke Kirihana, Satoru Meguro, Ryo Tanji, Akifumi Onagi, Ruriko Honda-Takinami, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Hidenori Akaihata, Soichiro Ogawa, Motohide Uemura, Yoshiyuki Kojima
{"title":"Evaluation of testicular stiffness in boys with unilateral cryptorchidism after orchiopexy by ultrasound strain elastography.","authors":"Yuichi Sato, Yusuke Kirihana, Satoru Meguro, Ryo Tanji, Akifumi Onagi, Ruriko Honda-Takinami, Kanako Matsuoka, Seiji Hoshi, Junya Hata, Hidenori Akaihata, Soichiro Ogawa, Motohide Uemura, Yoshiyuki Kojima","doi":"10.5387/fms.2023-19","DOIUrl":"10.5387/fms.2023-19","url":null,"abstract":"<p><strong>Purpose: </strong>We assessed the stiffness of unilateral undescended testes after orchiopexy, examining its value in tracking histopathological changes and fertility potential during postoperative follow-up. Additionally, we explored the optimal timing for surgery based on testicular stiffness.</p><p><strong>Patients and methods: </strong>Thirty-six boys who had been diagnosed with unilateral undescended testis and treated with orchiopexy were included in the study. Testicular stiffness was evaluated several times over respective follow-up periods by ultrasound strain elastography after orchiopexy. The strain ratios were measured as the ratios of the elasticities of the descended testis to those of the operated testes. The patients were divided into two groups based on the age at which they underwent orchiopexy:under < 2 years (Group A) and ≥ 2 years (Group B).</p><p><strong>Results: </strong>The mean strain ratios were 0.90 ± 0.32 and 0.92 ± 0.20 in Groups A and B, respectively. In Group A, the strain ratio was constant regardless of postoperative months (r = 0.01, p = 0.99); however, in Group B, it tended to increase with postoperative months (r = 0.42, p = 0.07).</p><p><strong>Conclusions: </strong>Evaluation of testicular stiffness may be useful for the estimation of histopathological changes and fertility potential in boys with unilateral undescended testes at follow-up appointments after orchiopexy. Our data indicate that performing orchiopexy as early as possible may be recommended to avoid testicular damage.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"57-64"},"PeriodicalIF":0.8,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139724417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differentiation of ovarian serous carcinoma from ovarian clear cell carcinoma using a 10-gene signature selected by comprehensive gene expression analysis. 利用综合基因表达分析选出的 10 个基因特征区分卵巢浆液性癌和卵巢透明细胞癌。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-04-26 Epub Date: 2024-03-15 DOI: 10.5387/fms.23-00011
Shinji Nomura, Takafumi Watanabe, Reiko Honma, Susumu Matsukura, Emi Ito, Jun-Ichi Imai, Yuichiro Kiko, Osamu Suzuki, Yuko Hashimoto, Manabu Kojima, Shigenori Furukawa, Shu Soeda, Shinya Watanabe, Keiya Fujimori
{"title":"Differentiation of ovarian serous carcinoma from ovarian clear cell carcinoma using a 10-gene signature selected by comprehensive gene expression analysis.","authors":"Shinji Nomura, Takafumi Watanabe, Reiko Honma, Susumu Matsukura, Emi Ito, Jun-Ichi Imai, Yuichiro Kiko, Osamu Suzuki, Yuko Hashimoto, Manabu Kojima, Shigenori Furukawa, Shu Soeda, Shinya Watanabe, Keiya Fujimori","doi":"10.5387/fms.23-00011","DOIUrl":"10.5387/fms.23-00011","url":null,"abstract":"<p><strong>Aim: </strong>Ovarian serous carcinoma (OSC) and ovarian clear cell carcinoma (OCCC) are two major histological types of epithelial ovarian carcinoma (EOC), each with different biological features and clinical behaviors. Although immunostaining is commonly used for differential diagnosis between OSC and OCCC, correct identification of EOC with mixed-type histology is sometimes a diagnostic challenge. The aim of the present study was to explore candidate genes as potential diagnostic biomarkers that distinguish OSC from OCCC.</p><p><strong>Methods: </strong>A total of 57 surgical specimens were obtained from EOC patients who had previously undergone primary debulking surgery. Total RNAs were extracted from fresh-frozen tissues of EOC patients, and were used for comprehensive gene expression analysis using DNA microarray technology.</p><p><strong>Results: </strong>Ten candidate genes, FXYD2, TMEM101, GABARAPL1, ARG2, GLRX, RBPMS, GDF15, PPP1R3B, TOB1, and GSTM3 were up-regulated in OCCC compared to OSC. All EOC patients were divided into two groups according to hierarchical clustering using a 10-gene signature.</p><p><strong>Conclusion: </strong>Our data suggest that the 10 candidate genes would be an excellent marker for distinguishing OSC from OCCC. Furthermore, the molecular signatures of the 10 genes may enlighten us on the differences in carcinogenesis, and provide a theoretical basis for OCCC's resistance to chemotherapy in the future.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"65-73"},"PeriodicalIF":0.8,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A reduction method for anterior opening displacement in thoracolumbarvertebral fractures with diffuse idiopathic skeletal hyperostosis using the skull clamp-assisted position. 弥漫性特发性骨骼增生症胸腰椎骨折患者使用颅骨钳辅助体位的前开口移位还原法。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-04-26 Epub Date: 2024-03-20 DOI: 10.5387/fms.23-00014
Hiroshi Kobayashi, Kazuyuki Watanabe, Yoshihiro Kobayashi, Kinshi Kato, Takuya Nikaido, Koji Otani, Shoji Yabuki, Shin-Ichi Konno, Yoshihiro Matsumoto
{"title":"A reduction method for anterior opening displacement in thoracolumbarvertebral fractures with diffuse idiopathic skeletal hyperostosis using the skull clamp-assisted position.","authors":"Hiroshi Kobayashi, Kazuyuki Watanabe, Yoshihiro Kobayashi, Kinshi Kato, Takuya Nikaido, Koji Otani, Shoji Yabuki, Shin-Ichi Konno, Yoshihiro Matsumoto","doi":"10.5387/fms.23-00014","DOIUrl":"10.5387/fms.23-00014","url":null,"abstract":"<p><p>Diffuse idiopathic skeletal hyperostosis (DISH) frequently occurs in the spine, resulting in unstable fractures. Treating thoracolumbar fractures in patients with DISH is often difficult because the anterior opening of the vertebral body is exacerbated by dislocation in the prone position, making reduction difficult. In this study, we introduced a novel skull clamp-assisted positioning (SAP) technique. The patient is placed in a supine position with a skull clamp used in cervical spine surgery before surgery to prevent the progression of dislocation and to restore the patient's position. Using this method, the mean difference in local kyphosis angle improved from -2.9 (±8.4)° preoperatively to 10.9 (±7.7)° postoperatively. Furthermore, posterior displacement decreased from a preoperative mean of 5.5 (±4.3) mm to 0.3 (±0.7) mm postoperatively. Complications such as neurological sequelae, implant fracture, and surgical site infection were not observed through one year of postoperative follow-up. SAP may decrease invasiveness and complications. Longer-term studies and larger sample sizes are needed to establish long-term efficacy and benefits.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"87-92"},"PeriodicalIF":0.8,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11140203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders. 严重进食障碍儿童口服营养与全肠外营养代谢参数的比较。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-03-22 DOI: 10.5387/fms.2023_02
Yuichi Suzuki, Shuntaro Itagaki, Maki Nodera, Kazuhide Suyama, Hirooki Yabe, Mitsuaki Hosoya
{"title":"Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders.","authors":"Yuichi Suzuki, Shuntaro Itagaki, Maki Nodera, Kazuhide Suyama, Hirooki Yabe, Mitsuaki Hosoya","doi":"10.5387/fms.2023_02","DOIUrl":"https://doi.org/10.5387/fms.2023_02","url":null,"abstract":"<p><strong>Background: </strong>This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration.</p><p><strong>Methods: </strong>We prospectively assessed the physical conditions of patients with eating disorders after the start of nutrition therapy. The assessments were performed at admission and at 2 and 4 weeks. Lipid metabolism was assessed based on triglyceride (TG), total cholesterol (TC), and free carnitine (FC) levels, as well as acylcarnitine/free carnitine (AC/FC) ratio.</p><p><strong>Results: </strong>A total of 18 patients were included. Of these, 12 and 6 received an oral diet (OD group) and total parenteral nutrition (TPN group), respectively. The mean body mass indexes at hospital admission were 12.8 kg/m<sup>2</sup> in the OD group and 12.7 kg/m<sup>2</sup> in the TPN group. At 2 weeks after the start of refeeding, TC, TG, and AC/FC levels were significantly lower in the TPN group than in the OD group. Other blood test results did not show any significant differences between the two groups.</p><p><strong>Conclusions: </strong>Fat-free glucose-based nutrition promoted lipid metabolism over a 2-week period after the start of refeeding, suggesting that balanced energy and lipid intake are essential, even in TPN.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outpatient rehabilitation for an older couple in a repopulated village 10 years after the Fukushima nuclear disaster:An embedded case study. 福岛核灾难10年后,一个重新人口稠密的村庄里一对老年夫妇的门诊康复:一个嵌入式案例研究。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-01-27 Epub Date: 2023-11-11 DOI: 10.5387/fms.2023-01
Yuta Saito, Sora Sato, Yoshitaka Nishikawa, Fumiya Oguro, Nobuaki Moriyama, Keiichiro Sato, Yurie Kobashi, Toyoaki Sawano, Akihiko Ozaki, Takeo Nakayama, Masaharu Tsubokura, Seiji Yasumura, Shohei Sakai
{"title":"Outpatient rehabilitation for an older couple in a repopulated village 10 years after the Fukushima nuclear disaster:An embedded case study.","authors":"Yuta Saito, Sora Sato, Yoshitaka Nishikawa, Fumiya Oguro, Nobuaki Moriyama, Keiichiro Sato, Yurie Kobashi, Toyoaki Sawano, Akihiko Ozaki, Takeo Nakayama, Masaharu Tsubokura, Seiji Yasumura, Shohei Sakai","doi":"10.5387/fms.2023-01","DOIUrl":"10.5387/fms.2023-01","url":null,"abstract":"<p><p>BackgroundLittle information is available on the role of community-based rehabilitation after a nuclear disaster. Here, we report the case of an older couple living in an area repopulated after the Fukushima nuclear disaster of 2011 who received outpatient rehabilitation.Case presentationAn 84-year-old woman underwent total hip arthroplasty (THA) after she fell and sustained a trochanteric fracture while caring for her husband with Alzheimer's disease. The 85-year-old husband experienced worsening behavioral and psychological symptoms of dementia (BPSD) following his wife's hospitalization. The couple received rehabilitation at an outpatient facility in a nearby village using a shuttle service. The woman's postoperative anxiety was relieved and her physical function improved. Moreover, the husband's BPSD symptoms decreased.ConclusionA wife and husband showed improvement in physical function after THA and alleviation of BPSD, respectively, following rehabilitation. In post-disaster, resource-scarce areas, older adults may benefit from utilizing the outpatient rehabilitation services available in the surrounding area.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"49-54"},"PeriodicalIF":0.8,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10867431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89719927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Roles of extracellular matrix in lung diseases. 细胞外基质在肺部疾病中的作用。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-01-27 Epub Date: 2024-01-25 DOI: 10.5387/fms.2023-07
Yoshinori Tanino
{"title":"Roles of extracellular matrix in lung diseases.","authors":"Yoshinori Tanino","doi":"10.5387/fms.2023-07","DOIUrl":"10.5387/fms.2023-07","url":null,"abstract":"<p><p>Extracellular matrix (ECM) is a non-cellular constituent found in all tissues and organs. Although ECM was previously recognized as a mere \"molecular glue\" that supports the tissue structure of organs such as the lungs, it has recently been reported that ECM has important biological activities for tissue morphogenesis, inflammation, wound healing, and tumor progression. Proteoglycans are the main constituent of ECM, with growing evidence that proteoglycans and their associated glycosaminoglycans play important roles in the pathogenesis of several diseases. However, their roles in the lungs are incompletely understood. Leukocyte migration into the lung is one of the main aspects involved in the pathogenesis of several lung diseases. Glycosaminoglycans bind to chemokines and their interaction fine-tunes leukocyte migration into the affected organs. This review focuses on the role chemokine and glycosaminoglycan interactions in neutrophil migration into the lung. Furthermore, this review presents the role of proteoglycans such as syndecan, versican, and hyaluronan in inflammatory and fibrotic lung diseases.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"1-9"},"PeriodicalIF":0.8,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10867433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139547471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reference values of lumbar spine range of motion by sex and age based on the assessment of supine trunk lateral bending-A preliminary study. 基于仰卧躯干侧弯评估的腰椎活动范围参考值(按性别和年龄)--初步研究。
IF 0.8
Fukushima Journal of Medical Science Pub Date : 2024-01-27 Epub Date: 2023-12-20 DOI: 10.5387/fms.2023-24
Shigetaka Nakanishi, Kazuyuki Watanabe, Kazuo Ouchi, Michiyuki Hakozaki, Naoyuki Oi, Shinichi Konno
{"title":"Reference values of lumbar spine range of motion by sex and age based on the assessment of supine trunk lateral bending-A preliminary study.","authors":"Shigetaka Nakanishi, Kazuyuki Watanabe, Kazuo Ouchi, Michiyuki Hakozaki, Naoyuki Oi, Shinichi Konno","doi":"10.5387/fms.2023-24","DOIUrl":"10.5387/fms.2023-24","url":null,"abstract":"<p><p>[Purpose] The purpose of this study was to clarify the preliminary reference values for the lumbar spine range of motion associated with lateral bending exercises by gender and age group. [Methods] Subjects were 82 volunteers without low back pain, including five males and five females in each age group from 16-19 to 80-89 years. All subjects underwent radiographs of the lumbar spine with lateral flexion; the range of lateral flexion of the vertebrae from T12 to the sacrum (ROLB) was measured twice by three observers. [Results] The ROLB of the entire T12-S1 of all subjects showed a significant negative correlation with age in both sexes (p < 0.01). The ROLB of the lumbar spine tended to be greater in females, with a statistically significant difference between those aged 16-19 and 70-79 (p < 0.05). Lateral flexion angles for each intervertebral segment were largest at L3-L4 and smallest at L5-S1 (0.7°). [Conclusion] Lumbar ROLB reference values were examined by gender and age group; ROLB was greatest in L3-L4, and ROLB tended to be lower in older age groups.</p>","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"25-33"},"PeriodicalIF":0.8,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10867432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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