Fukushima Journal of Medical Science最新文献_第2页

Rice bodies in nontuberculous mycobacterial tenosynovitis of the wrist joint. 腕关节非结核性分枝杆菌腱鞘炎中的稻体。

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Fukushima Journal of Medical Science Pub Date : 2026-10-10 Epub Date: 2026-03-25 DOI: 10.5387/fms.25-00035

Itaru Ogawa, Takuya Kameda, Chiharu Nagashima, Kazuki Kobayashi, Yoichi Kaneuchi, Takeo Suzuki, Michiyuki Hakozaki, Takuya Nikaido, Yoshihiro Matsumoto

引用次数: 0

A case of circumferential caval penetration caused by an inferior vena cava filter with asymptomatic duodenal perforation. 由下腔静脉滤过器引起的十二指肠无症状穿孔的绕周腔静脉穿透1例。

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Fukushima Journal of Medical Science Pub Date : 2026-10-10 Epub Date: 2026-03-25 DOI: 10.5387/fms.25-00010

Keiichi Ishida, Yoichi Sato, Hironori Uekita, Junichiro Haga

引用次数: 0

Unilateral eosinophilic fasciitis: a case report and review of the literature. 单侧嗜酸性筋膜炎1例报告及文献复习。

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Fukushima Journal of Medical Science Pub Date : 2026-10-10 DOI: 10.5387/fms.26-00019

Maki Takada, Miyuki Yamamoto, Takashi Ito, Toshiyuki Yamamoto

{"title":"Unilateral eosinophilic fasciitis: a case report and review of the literature.","authors":"Maki Takada, Miyuki Yamamoto, Takashi Ito, Toshiyuki Yamamoto","doi":"10.5387/fms.26-00019","DOIUrl":"https://doi.org/10.5387/fms.26-00019","url":null,"abstract":"A 59-year-old Japanese man developed pruritus and swelling of the right dorsal foot after weeding his garden in a crouching position for approximately one hour. Over a period of five months, the swelling, as well as skin induration, progressed unilaterally from the right thigh to the lower leg and dorsal foot. Laboratory tests, including eosinophil fraction and inflammatory markers, were within normal limits, and computed tomography showed no evidence of deep vein thrombosis or malignancy. A full-thickness biopsy including the fascia revealed marked fascial thickening with fibrosis of the subcutaneous connective tissue, and perivascular lymphocytic inflammatory infiltrates without conspicuous eosinophils, leading to a diagnosis of eosinophilic fasciitis. Oral prednisolone (30 mg/day) resulted in gradual improvement. To the best of our knowledge, 11 cases of unilateral eosinophilic fasciitis have been reported (three in Japan and eight outside Japan). Including the present case (total 12), six cases lacked peripheral blood eosinophilia, and seven lacked significant eosinophilic infiltration in tissue; five showed neither. Eosinophilic fasciitis should be considered even in the absence of eosinophilia; therefore, early full-thickness biopsy including the fascia is essential for accurate diagnosis.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New-onset of polymyalgia rheumatica in an elderly patient with calcium pyrophosphate deposition (CPPD) disease. 老年焦磷酸钙沉积（CPPD）病患者新发风湿性多肌痛1例。

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Fukushima Journal of Medical Science Pub Date : 2026-10-10 Epub Date: 2026-03-25 DOI: 10.5387/fms.25-00034

Kiysohi Migita, Toshiyuki Tsurumoto, Haruki Matsumoto, Shuhei Yoshida, Kazufumi Yamasaki, Fumi Mori, Tomoyuki Asano, Ichiro Isomoto, Atsushi Kawakami

{"title":"New-onset of polymyalgia rheumatica in an elderly patient with calcium pyrophosphate deposition (CPPD) disease.","authors":"Kiysohi Migita, Toshiyuki Tsurumoto, Haruki Matsumoto, Shuhei Yoshida, Kazufumi Yamasaki, Fumi Mori, Tomoyuki Asano, Ichiro Isomoto, Atsushi Kawakami","doi":"10.5387/fms.25-00034","DOIUrl":"10.5387/fms.25-00034","url":null,"abstract":"We herein present an 87-year-old febrile female patient with knee joint pain. The presence of calcium pyrophosphate crystals in synovial fluids led to a diagnosis of calcium pyrophosphate dihydrate (CPPD) disease. She was treated with nonsteroidal anti-inflammatory drugs (NSAIDs), resulting in the resolution of the knee joint arthritis and inflammatory signs. However, 3 weeks from the first onset of knee joint pain, she relapsed with febrile episodes accompanied by myalgia around the shoulder and morning stiffness. Ultrasonography revealed bilateral long head biceps tenosynovitis. A diagnosis of polymyalgia rheumatica (PMR), considered to be a complication in addition to the pre-existing CPPD disease, was made according to the EULAR/ACR provisional classification criteria for PMR. Steroid therapy resolved the symptoms. This case demonstrates the importance of considering the possibility of overlapping PMR in patients with an atypical clinical course of CPPD disease. Careful differentiation of PMR and CPPD disease is necessary in elderly patients with atypical inflammatory arthropathy.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":"349-354"},"PeriodicalIF":0.9,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-communicable diseases among subcontract and primary workers involved in decontamination after the fukushima daiichi nuclear power plant accident: an observational study. 福岛第一核电站事故后参与去污工作的分包工和初级工的非传染性疾病：一项观察性研究。

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Fukushima Journal of Medical Science Pub Date : 2026-10-10 DOI: 10.5387/fms.25-00049

Fumiya Oguro, Yoshitaka Nishikawa, Toyoaki Sawano, Yurie Kobashi, Naomi Ito, Masaharu Tsubokura

{"title":"Non-communicable diseases among subcontract and primary workers involved in decontamination after the fukushima daiichi nuclear power plant accident: an observational study.","authors":"Fumiya Oguro, Yoshitaka Nishikawa, Toyoaki Sawano, Yurie Kobashi, Naomi Ito, Masaharu Tsubokura","doi":"10.5387/fms.25-00049","DOIUrl":"https://doi.org/10.5387/fms.25-00049","url":null,"abstract":"Objective: Evidence on the population-level burden of major non-communicable diseases (NCDs) among Fukushima decontamination workers is limited, and it remains unclear whether subcontracted employment, a potential marker of employment-related vulnerability, is associated with NCD prevalence and health risk awareness. We therefore compared the prevalence of NCDs by employment status.Methods: We conducted a cross-sectional study using health checkup data from 2,790 workers (2011-2017). Data concerning hypertension, diabetes mellitus, and dyslipidemia were evaluated, along with the workers' self-reported awareness of diagnosis or treatment. Employment status was categorized as subcontracted worker or prime contractor worker. Group differences were assessed using Welch's t-tests and chi-squared tests, and quantile regression adjusted for age and sex.Results: The study included a total of 2,790 decontamination workers, of whom 1,716 were subcontracted workers (median age, 51 years; range, 18-82). The subcontracted workers had higher mean systolic blood pressure, a lower prevalence of self-reported hypertension, and higher blood glucose levels in extreme cases.Conclusions: The subcontracted workers had higher systolic blood pressure despite lower self-reported hypertension. Future studies should investigate factors contributing to differences in NCD prevalence between subcontracted and prime contractor workers, such as lower self-awareness and barriers to healthcare access among subcontracted workers.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Standardized uptake value in normal bone using stand-alone SPECT with ^99mTc hydroxymethylene diphosphonate. 使用99mTc羟亚甲基二膦酸盐独立SPECT对正常骨的标准化摄取值。

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Fukushima Journal of Medical Science Pub Date : 2026-10-10 DOI: 10.5387/fms.26-00004

Hiroki Suenaga, Shiro Ishii, Keijiro Saito, Junko Hara, Ryo Yamakuni, Shigeyasu Sugawara, Kenji Fukushima, Hiroshi Ito

{"title":"Standardized uptake value in normal bone using stand-alone SPECT with 99mTc hydroxymethylene diphosphonate.","authors":"Hiroki Suenaga, Shiro Ishii, Keijiro Saito, Junko Hara, Ryo Yamakuni, Shigeyasu Sugawara, Kenji Fukushima, Hiroshi Ito","doi":"10.5387/fms.26-00004","DOIUrl":"https://doi.org/10.5387/fms.26-00004","url":null,"abstract":"Objective: To evaluate the feasibility of standardized uptake value (SUV) measurement and availability of bone single photon emission computed tomography (SPECT) images using a stand-alone SPECT system.Methods: 30 patients with prostate cancer without bone metastases underwent 99mTc-HMDP bone SPECT using a stand-alone system. SUVmax, SUVpeak, and SUVmean were measured with standardized VOIs at C6, Th6, L3, S1, the sternum, femoral necks, iliac wings, and scapular spines. Associations with age, height, weight, and BMI were assessed using Pearson's correlation.Results: Across sites, mean±SD SUVmax, SUVpeak, and SUVmean were 2.53±0.96, 2.38±0.89, and 2.03±0.76. SUVmax ranged from 1.41±0.30 (femoral neck) to 3.55±0.74 (ilium). Regional coefficients of variation were 21-27%, and SUVs were lower than values reported for SPECT/CT. Age correlated positively with SUVmax in the sacrum and scapula and slightly negatively in the lumbar spine and sternum. Height correlated positively with sternum SUVmax and negatively with sacrum and scapula SUVmax. Weight and BMI correlated negatively with SUVmax in the sacrum, femoral neck, ilium, and scapula; BMI was also negatively correlated in the lumbar spine.Conclusion: Bone SUVs measured with SPECT-only were lower than SPECT/CT but showed modest between-patient variability, supporting the feasibility of quantitative bone SPECT using a stand-alone system.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of motor function deterioration on swallowing function in older adults: a narrative review. 运动功能恶化对老年人吞咽功能的影响：一项叙述性回顾。

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Fukushima Journal of Medical Science Pub Date : 2026-09-04 DOI: 10.5387/fms.26-00008

Mari Sato, Tetsuo Hayashi

{"title":"The impact of motor function deterioration on swallowing function in older adults: a narrative review.","authors":"Mari Sato, Tetsuo Hayashi","doi":"10.5387/fms.26-00008","DOIUrl":"https://doi.org/10.5387/fms.26-00008","url":null,"abstract":"Similar to motor function, swallowing function declines with age. Dysphagia in older adults has detrimental effects, including an increased risk of pneumonia and mortality, highlighting the importance of early detection and intervention at the community level. This review aims to comprehensively discuss the relationship between motor and swallowing functions in older adults through a narrative review, including existing limitations, with the goal of contributing to the early detection of dysphagia and the development of treatment strategies.Regarding the relationship between swallowing and whole-body skeletal muscle strength, associations between swallowing or tongue pressure and grip strength have been reported. A relationship between tongue pressure and respiratory muscles has been hypothesized, given the association between tongue pressure and walking function, which focuses on age-related changes in neural function, and the fact that certain swallowing-related muscles contract in coordination with respiratory movements.Detailed assessment of research, such as endoscopic swallowing studies, and verification of causal relationships through intervention and longitudinal studies are expected to contribute to the early detection and treatment of dysphagia.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Redo cardiac and great vessel surgery: necessity of meticulous preparation and contingency planning. 重做心脏和大血管手术：精心准备和应急计划的必要性。

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Fukushima Journal of Medical Science Pub Date : 2026-08-13 DOI: 10.5387/fms.25-00051

Ken-Ichi Imasaka

{"title":"Redo cardiac and great vessel surgery: necessity of meticulous preparation and contingency planning.","authors":"Ken-Ichi Imasaka","doi":"10.5387/fms.25-00051","DOIUrl":"10.5387/fms.25-00051","url":null,"abstract":"Recent advances in surgical techniques and perioperative management have significantly improved the outcomes of cardiac and/or thoracic aortic surgery compared with earlier decades. However, redo procedures remain particularly challenging, with surgical results still inferior to those of primary operations. The complexity arises from altered anatomy, dense adhesions, and increased risks of injury to vital structures. Careful surgical planning is therefore indispensable, and four strategic steps are especially critical. First, meticulous preoperative assessment with contrast-enhanced computed tomography is required to delineate the spatial relationship between the heart, great vessels, and sternum. Second, the optimal approach to intrapericardial access must be determined, including whether cardiopulmonary bypass should be instituted prior to median sternotomy. Third, safe and deliberate dissection of adhesions surrounding the heart and great vessels is essential to avoid catastrophic complications. Finally, effective organ protection strategies, particularly for the brain and myocardium, are paramount to ensure favorable outcomes. This review highlights common pitfalls encountered in redo cardiac and/or thoracic aortic surgery and discusses practical strategies to overcome them, aiming to provide surgeons with a structured framework for improving safety and results in these high-risk procedures.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148725498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathophysiological and clinical significance of hepatokine Fetuin-A and myocardial N-myristoylation in heart failure. 心衰患者肝因子Fetuin-A及心肌n-肉豆蔻酰化的病理生理及临床意义。

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Fukushima Journal of Medical Science Pub Date : 2026-08-13 DOI: 10.5387/fms.26-00021

Yusuke Tomita, Tomofumi Misaka, Tetsuro Yokokawa, Yasuchika Takeishi

{"title":"Pathophysiological and clinical significance of hepatokine Fetuin-A and myocardial N-myristoylation in heart failure.","authors":"Yusuke Tomita, Tomofumi Misaka, Tetsuro Yokokawa, Yasuchika Takeishi","doi":"10.5387/fms.26-00021","DOIUrl":"10.5387/fms.26-00021","url":null,"abstract":"Heart failure (HF) is a systemic syndrome in which myocardial remodeling and multiorgan dysfunction exacerbate each other. This review focuses on the hepatokine Fetuin-A and the post-translational modification N-myristoylation in HF. Regarding Fetuin-A, we first demonstrated that circulating Fetuin-A levels were significantly lower in HF patients than in control subjects without structural heart disease. This reduction was associated with hepatic hypoperfusion. In a prospective study of 202 HF patients who underwent cardiopulmonary exercise testing, the combination of lower Fetuin-A and impaired exercise tolerance was independently associated with increased risk of cardiac events, suggesting that Fetuin-A could serve as a novel mediator of cardiac-hepatic-peripheral interaction. Regarding N-myristoylation, expression of N-myristoyltransferase 2 (NMT2) was significantly reduced in failing hearts. Cardiac-specific NMT2 knockdown exacerbated cardiac dysfunction, whereas AAV9-mediated NMT2 gene transfer attenuated cardiac remodeling and HF. Click chemistry-based proteomics identified MARCKS as a crucial substrate, and N-myristoylation of MARCKS prevented pathological hypertrophy by promoting its membrane localization, thereby suppressing CaMKII-HDAC4 signaling. These findings indicate that Fetuin-A and NMT2-dependent N-myristoylation play important roles in HF pathophysiology and represent potential novel therapeutic targets.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of interscalene brachial plexus block with postural modification for inferior shoulder dislocation with fracture: a case report. 斜角肌间臂丛阻滞加体位改良治疗下肩脱位骨折1例。

IF 0.9

Fukushima Journal of Medical Science Pub Date : 2026-08-13 DOI: 10.5387/fms.25-00053

Takeru Yokota, Hiroki Sato, Toshiki Sato, Yota Kaneko, Michiyuki Hakozaki, Yoshihiro Matsumoto

{"title":"Utility of interscalene brachial plexus block with postural modification for inferior shoulder dislocation with fracture: a case report.","authors":"Takeru Yokota, Hiroki Sato, Toshiki Sato, Yota Kaneko, Michiyuki Hakozaki, Yoshihiro Matsumoto","doi":"10.5387/fms.25-00053","DOIUrl":"10.5387/fms.25-00053","url":null,"abstract":"Background: Inferior shoulder dislocation (luxation erecta) is a rare condition, accounting for approximately 0.5% of all shoulder dislocations, typically resulting from high-energy trauma, such as falls or motor vehicle accidents.Case presentation: This case involved a man in his late 50s who sustained an inferior left shoulder dislocation with a greater tuberosity fracture after falling 2 m during work-related activities. Due to the patient's elevated BMI and absence of an anesthesiologist, general anesthesia was not feasible and local anesthesia led to inadequate pain relief and complicated reduction. We employed an interscalene brachial plexus block, enhanced by a modified approach involving positional adjustment and elastic taping, to address the abducted arm position and potential cervical spine concerns. Reduction was successfully performed without complications, such as neurovascular injury and respiratory issues.Conclusions: This report describes a modified interscalene block technique that may serve as a practical alternative in selected cases where general anesthesia is unavailable.","PeriodicalId":44831,"journal":{"name":"Fukushima Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0