Journal of Neurological Surgery Reports最新文献

Malignant Transformation of a Vestibular Schwannoma Without Previous Radiation Exposure: Illustrative Case and Literature Review.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-04-03 eCollection Date: 2025-04-01 DOI: 10.1055/a-2547-5320

Chao Li, James Fowler, Kishore Balasubramanian, Kar-Ming Fung, Piao Zhe, William W Wu

{"title":"Malignant Transformation of a Vestibular Schwannoma Without Previous Radiation Exposure: Illustrative Case and Literature Review.","authors":"Chao Li, James Fowler, Kishore Balasubramanian, Kar-Ming Fung, Piao Zhe, William W Wu","doi":"10.1055/a-2547-5320","DOIUrl":"10.1055/a-2547-5320","url":null,"abstract":"Background: Although malignant transformation of benign vestibular schwannoma (VS) preceded by irradiation has been well documented, few studies have demonstrated malignant transformation in the absence of radiation. Here, we present a rare case of the malignant transformation of a benign VS to a malignant peripheral nerve sheath tumor (MPNST) in the absence of prior irradiation. Additionally, we conducted a literature search to identify all other reported cases of MPNST arising from VS under similar conditions.Case presentation: A 75-year-old female presented to the hospital with a 1-month history of left-sided facial numbness, loss of taste on the left side of her tongue, severe dysarthria, and recent-onset cranial nerve VI and VII palsies. MRI of the brain with and without contrast demonstrated an enlarging cerebellopontine angle mass and signs of brainstem compression. The patient underwent a left retrosigmoid craniotomy and surgical resection. Pathology and immunohistochemistry sequencing findings were consistent for MPNST with rhabdomyoblastic differentiation (malignant triton tumor). An outside review of the case by a large academic institution concurred with the diagnosis. The patient did not report any previous history of irradiation.Conclusion: A total of 11 cases, including ours, have appropriate S-100 immunochemical reactivity to confirm malignant transformation. Due to the limited number of reported cases of MPNST arising from VS without prior irradiation, information regarding pathogenesis and pathological diagnosis is scarce. We provide valuable additions to the literature, including next-generation sequencing data, to identify potentially targetable genetic changes and help elucidate the pathogenesis of MPNST.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 2","pages":"e57-e64"},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma of the Skull Base: Report of a Case and Literature Review.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-04-03 eCollection Date: 2025-04-01 DOI: 10.1055/a-2556-0732

Monica S Trent, Beverly Wang, Edward C Kuan

{"title":"Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma of the Skull Base: Report of a Case and Literature Review.","authors":"Monica S Trent, Beverly Wang, Edward C Kuan","doi":"10.1055/a-2556-0732","DOIUrl":"10.1055/a-2556-0732","url":null,"abstract":"Objective: Chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH) is a rare benign growth within the nasal cavity or paranasal sinuses. We aim to highlight the pathogenesis and clinical presentation of an extremely rare benign mass within the nasal cavity and demonstrate the workup, diagnosis, and management of this rare lesion, as well as review the literature.Methods: Retrospective review of a patient presenting with COREAH of the sinonasal cavity treated at a single tertiary academic medical center. The MEDLINE database was additionally searched for all case series or reports of sinonasal or skull base COREAH.Results: A total of sixteen articles were identified for review. In addition to the current case, a total of nineteen patients were identified in literature found to have sinonasal or skull base COREAH. The most common primary sites of attachment were the lateral nasal wall and posterior septum. Only two cases were identified with skull base attachment. Computed topography (CT) was employed in 84.2% of patients, and CT with MRI was utilized in 26.3% of patients. Endoscopic resection was performed in 100% of patients, with one recurrence reported in the literature and one incomplete resection requiring revision surgery.Conclusion: COREAH is an extremely rare hamartoma consisting of glandular proliferation with cartilaginous and osseous stroma. COREAH is symptomatic in 100% of reported cases in the literature, and complete surgical resection is often curative. Our case represents the longest follow-up reported with 4 years postoperatively revealing no growth or recurrence of COREAH.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 2","pages":"e50-e56"},"PeriodicalIF":0.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Research Primer for Medical Students: Behind the Curtain, a Framework on Peer Review for Trainees.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI: 10.1055/a-2554-2357

Taylor Niznik, Sherwin A Tavakol, Tressie Stephens, Andrew M Bauer, Ian F Dunn, Christopher S Graffeo

{"title":"Clinical Research Primer for Medical Students: Behind the Curtain, a Framework on Peer Review for Trainees.","authors":"Taylor Niznik, Sherwin A Tavakol, Tressie Stephens, Andrew M Bauer, Ian F Dunn, Christopher S Graffeo","doi":"10.1055/a-2554-2357","DOIUrl":"10.1055/a-2554-2357","url":null,"abstract":"Academic scholarship is an increasingly emphasized component of undergraduate medical education (UME), in particular since the USMLE Step 1 examination transitioned to a pass/fail grading scheme in 2022. Peer review is a cornerstone of academic publishing, but essentially no formal training exists at the UME or graduate medical education levels to prepare trainees for participation in the process as authors or reviewers. This clinical research primer presents an introductory set of guidelines and pearls to empower trainee participation in the peer-review process as both authors and reviewers. We outline a systematic approach to manuscript evaluation and recommend a nonlinear strategy that begins with the Abstract and Methods, followed by Figures, Tables, and Results, concluding with the Discussion. This framework includes guidelines for constructing effective reviews, from initial summary and overall recommendations to specific, actionable comments. Participation in peer review can also advance trainees' scholarly development by exposing gaps in literature that inspire new research questions and developing their ability to anticipate and address potential reviewer critiques in their own manuscript preparation. While initial implementation requires close supervision from experienced mentors, this structured approach streamlines the peer-review learning process and provides substantial benefits for all participants in academic publishing, enhancing both mentorship relationships and scholarly development.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e45-e49"},"PeriodicalIF":0.6,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11957855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skull Base Rhabdomyosarcoma Mimicking Osteomyelitis in a Pediatric Patient. 一名小儿患者的颅底横纹肌肉瘤模拟骨髓炎

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-03-20 eCollection Date: 2025-01-01 DOI: 10.1055/a-2544-3543

Avraham Adelman, Landon Richardson, Nikita Chapurin, Brian C Lobo, Si Chen

{"title":"Skull Base Rhabdomyosarcoma Mimicking Osteomyelitis in a Pediatric Patient.","authors":"Avraham Adelman, Landon Richardson, Nikita Chapurin, Brian C Lobo, Si Chen","doi":"10.1055/a-2544-3543","DOIUrl":"10.1055/a-2544-3543","url":null,"abstract":"Rhabdomyosarcoma (RMS) is a rare malignant tumor, affecting 4.58 per 1 million children, with approximately 35% occurring in the head and neck. Skull base RMS commonly presents at advanced stages and delays diagnosis due to its overlapping features with other skull base pathology, and difficulty accessing the lesion for biopsy. This case illustrates these challenges in skull base RMS mimicking osteomyelitis of the petrous apex. Case: A 6-year-old immunocompetent female, with a history of two acute otitis media episodes, presented with a 3-week history of sixth cranial nerve palsy and sudden-onset complete seventh cranial nerve palsy. She did not have pain or otorrhea. Computed tomography (CT) and magnetic resonance imaging revealed a 1.3 cm left petrous apex enhancing lesion with extension into the mastoid and clivus with surrounding bony and soft tissue destruction. A nuclear medicine scan (Technetium-99m followed by gallium) demonstrated avid uptake in the left petrous apex. The working diagnosis was skull base osteomyelitis, for which the patient received 2.5 weeks of antibiotics. After failing to improve, repeat imaging showed significant progression of the disease and extension into the nasopharynx and sphenoid sinus. An endoscopic trans-sphenoidal biopsy was performed with pathology consistent with RMS. CT chest revealed lung metastases. The patient partially responded to chemotherapy with vincristine, actinomycin-D, and cyclophosphamide alternating with vincristine and irinotecan. During week 13 of chemotherapy, she received concomitant proton therapy to a total dose of 5040 cGyRBE. Five months after diagnosis, she developed leptomeningeal spread, which was further complicated by meningitis, and passed away.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e41-e44"},"PeriodicalIF":0.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Approaches to Optic Nerve Decompression in Osteopetrosis: A Review of Endoscopic Endonasal and Transcaruncular Techniques.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-03-20 eCollection Date: 2025-01-01 DOI: 10.1055/a-2544-3435

Rita Maria Jalkh, Patrick Abou Raji Feghali, Ghena Lababidi, Houssein Darwish, Zeina Korban

{"title":"Surgical Approaches to Optic Nerve Decompression in Osteopetrosis: A Review of Endoscopic Endonasal and Transcaruncular Techniques.","authors":"Rita Maria Jalkh, Patrick Abou Raji Feghali, Ghena Lababidi, Houssein Darwish, Zeina Korban","doi":"10.1055/a-2544-3435","DOIUrl":"10.1055/a-2544-3435","url":null,"abstract":"Osteopetrosis is a rare genetic disorder characterized by impaired osteoclast function and excessive bone density, often leading to compressive optic neuropathy due to bony overgrowth of the optic canal. Timely surgical intervention is critical for preventing permanent vision loss in affected patients. This review summarizes the available literature on the surgical techniques of endoscopic endonasal optic nerve decompression (EEOND) and the transcaruncular approach in osteopetrosis patients. EEOND is a minimally invasive technique that offers excellent visualization, advanced instrumentation, and access to the optic nerve through the nasal corridor and requires mastering the anatomy of the sphenoid bone to achieve success. However, challenges arise from the dense and brittle nature of the bone in osteopetrosis, complicating the procedure. The transcaruncular approach provides a targeted route to the medial optic canal with minimal external scarring. However, its limited scope may not suffice for extensive decompression in severe cases. Early surgical intervention correlates with better visual outcomes, particularly in pediatric patients who are at higher risk for rapid progression of vision loss. Integrating advanced imaging and hybrid surgical techniques may enhance decompression efficacy. In conclusion, both EEOND and the transcaruncular approach are valuable for managing optic nerve compression in osteopetrosis, each with distinct advantages and limitations. Ongoing advancements in surgical techniques and a multidisciplinary approach are essential to optimize patient outcomes.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e36-e40"},"PeriodicalIF":0.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11925620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subependymal Giant Cell Astrocytoma in an Adult without Tuberous Sclerosis: Systematic Review and Illustrative Case Example.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-02-27 eCollection Date: 2025-01-01 DOI: 10.1055/a-2530-5965

Brandon M Holler, Alexander R Evans, Abigail York, Christopher S Graffeo

{"title":"Subependymal Giant Cell Astrocytoma in an Adult without Tuberous Sclerosis: Systematic Review and Illustrative Case Example.","authors":"Brandon M Holler, Alexander R Evans, Abigail York, Christopher S Graffeo","doi":"10.1055/a-2530-5965","DOIUrl":"10.1055/a-2530-5965","url":null,"abstract":"Background Subependymal giant cell astrocytoma (SEGA) is a rare neoplasm arising from subependymal tissue. Predominantly associated with the tuberous sclerosis complex (TSC), SEGA may present with a range of diverse symptoms, most commonly seizures or neurocutaneous features of TSC. We present a novel case of sporadic SEGA in a 59-year-old woman who presented with acute intraparenchymal hemorrhage (IPH). Methods Systematic literature review and illustrative case example. Results A 59-year-old woman presented with a headache decreased level of consciousness, and acute IPH involving the anterior septum pellucidum and right medial caudate head. MRI was concerning for an underlying neoplasm, which grew slowly on follow-up imaging, prompting microsurgical resection. A gross total resection was achieved, and postoperative pathology confirmed SEGA (WHO grade I) without TSC1/2 mutation. She remained disease-free and neurologically intact at 1-year follow-up. A systematic review identified seven publications that revealed pathologically confirmed SEGA in nine adult patients without TSC. Headache, papilledema, and visual disturbances were the most common presenting symptoms. Treatment protocols included microsurgical resection versus biopsy followed by radiographic surveillance, and the overall rate of symptom-free survival was at least 80% as of the last follow-up. Conclusion We report the tenth case of sporadic SEGA in an adult patient without TSC, as well as an associated systematic review of this rare neoplastic entity. Further study is required to identify risk factors for the development of sporadic SEGA, as well as potential avenues for the management of this disease that may depart from the standard protocol in pediatric TSC patients.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e31-e35"},"PeriodicalIF":0.6,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11867713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Keyhole Mini-Craniotomy Middle Fossa Approach for Tegmen Repair: A Case Series and Technical Instruction.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1055/a-2514-7338

Syed M Adil, Tanner J Zachem, Jordan K Hatfield, Jihad Abdelgadir, Kimberly Hoang, Patrick J Codd

{"title":"Keyhole Mini-Craniotomy Middle Fossa Approach for Tegmen Repair: A Case Series and Technical Instruction.","authors":"Syed M Adil, Tanner J Zachem, Jordan K Hatfield, Jihad Abdelgadir, Kimberly Hoang, Patrick J Codd","doi":"10.1055/a-2514-7338","DOIUrl":"10.1055/a-2514-7338","url":null,"abstract":"Background and Importance Tegmen defects associated with cerebrospinal fluid (CSF) leaks are a rare pathology that can result in severe complications if left untreated. There is no universal optimal surgical algorithm for repair, although the most common techniques are the middle fossa craniotomy (traditionally 25 cm 2 in area), the transmastoid approach, or both. Here, we describe successful use of a keyhole mini-craniotomy, only 6 cm 2 in area, without mastoidectomy or days of lumbar drainage. Clinical Presentation Three patients presented with right-sided CSF otorrhea and hearing loss, with varying sizes of tegmen defects and associated encephaloceles. Keyhole craniotomies measuring 3 × 2 cm were used to perform a multilayer repair comprising an intradural collagen dural substitute, extradural fascial graft, extradural collagen dural substitute, fibrin sealant, and sometimes bony reconstruction using partial thickness craniotomy grafting. All patients were discharged on postoperative day 1 or 2, with no recurrence of symptoms at 6 months. Conclusion The keyhole craniotomy approach does not sacrifice the extent of operative access for this pathology. This minimally invasive approach can likely be used more often without need for concomitant mastoidectomy, ultimately enabling shorter hospital stays and more rapid recovery.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e19-e23"},"PeriodicalIF":0.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete Hearing Recovery after Retrosigmoid Resection of Jugular Foramen Schwannoma with Concurrent Ipsilateral Vestibular Schwannoma.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-02-06 eCollection Date: 2025-01-01 DOI: 10.1055/a-2516-7311

Achilles A Kanaris, Nicholas E F Hac, Stephen T Magill, Kevin Y Zhan

{"title":"Complete Hearing Recovery after Retrosigmoid Resection of Jugular Foramen Schwannoma with Concurrent Ipsilateral Vestibular Schwannoma.","authors":"Achilles A Kanaris, Nicholas E F Hac, Stephen T Magill, Kevin Y Zhan","doi":"10.1055/a-2516-7311","DOIUrl":"10.1055/a-2516-7311","url":null,"abstract":"Introduction Cerebellopontine angle (CPA) tumors frequently present with hearing loss, which influences whether a hearing-preservation versus hearing ablative surgical approach is chosen. We discuss a case of complete hearing recovery after resection of a jugular foramen schwannoma (JFS) in a patient who also had a small intracanalicular vestibular schwannoma (VS). Case A 46-year-old woman presented with left ear fullness, tinnitus, and imbalance for 9 months. She had no lower cranial nerve dysfunction. Audiometry demonstrated Class D hearing with 4% word recognition on the left. Vestibular testing showed absent caloric response on the left and subtle central findings. Magnetic resonance imaging demonstrated a left 3.3-cm JFS and separate left 1-cm intracanalicular VS. A retrosigmoid approach was performed for a radical subtotal resection of the JFS, relieving the mass effect on the vestibulocochlear nerve. The small intracanalicular VS was not manipulated. Pathology confirmed schwannoma with neurofibromatosis type 2 (NF2) mutation in the tumor but normal NF2 germline. Postoperative audiometry at 6 weeks showed normal audiometric thresholds with 100% discrimination. Subtle left caloric response was noted on postoperative vestibular testing and central oculomotor findings improved. Discussion The presented case describes the management of concurrent ipsilateral VS and JFS in the absence of NF2 and demonstrates a unique complete and rapid recovery of hearing following JFS resection without manipulation of concurrent VS. This case supports the use of a hearing-preservation approach in similar cases and corroborates previous reports of hearing recovery following resection of non-VS CPA tumors with hearing-preservation approaches.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e24-e30"},"PeriodicalIF":0.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel Technique for Nasopharyngeal Stenosis Repair: Combined Transoral Robotic and Endonasal Approaches for Enhanced Visualization and Surgical Precision.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-01-27 eCollection Date: 2025-01-01 DOI: 10.1055/a-2466-7414

Russel T Wagner, Sammy Khalili, Blake Henning, Neil S Mundi

引用次数: 0

Single-Session Surgical Intervention with Resection of a Primary Cranial Osteosarcoma and Cranioplasty using a 3D-Printed Craniotomy Template and Cranioplasty Molds.

IF 0.6

Journal of Neurological Surgery Reports Pub Date : 2025-01-23 eCollection Date: 2025-01-01 DOI: 10.1055/a-2508-0868

Sven Duda, Philipp Ivanyi, Mohamed Omar, Christian Hartmann, Eugen Musienko, Heinrich Wessling

{"title":"Single-Session Surgical Intervention with Resection of a Primary Cranial Osteosarcoma and Cranioplasty using a 3D-Printed Craniotomy Template and Cranioplasty Molds.","authors":"Sven Duda, Philipp Ivanyi, Mohamed Omar, Christian Hartmann, Eugen Musienko, Heinrich Wessling","doi":"10.1055/a-2508-0868","DOIUrl":"10.1055/a-2508-0868","url":null,"abstract":"Although osteosarcomas are the most frequent primary malignant bone tumors, the primary cranial manifestation of this condition is very rare with only a limited number of cases presented in the literature. We present the case of a 20-year-old male patient who underwent single-session surgical intervention for resection of right frontal osteosarcoma with a tailor-made craniotomy and cranioplasty using virtually designed 3D-printed templates and molds. Subsequently, the patient was treated according to the EURAMOS protocol and received adjuvant systemic chemotherapy. At 18-month follow-up, the patient was clinically asymptomatic, and both the magnetic resonance imaging scan of the head and the staging computed tomography showed no signs of tumor recurrence or metastases. The case presented shows that the use of 3D-printed molds facilitate a safe preoperative planning of the resection area and a single-session surgery including a custom-made cranioplasty responding to the highest esthetical standards.","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 1","pages":"e8-e13"},"PeriodicalIF":0.6,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0