{"title":"左脑室和第三脑室非典型畸胎瘤/横纹肌样瘤（AT/RT）切除术的半球间-经皮质入路。","authors":"Douglas Chung, Patrick F O' Brien, Hasan Syed","doi":"10.1055/a-2701-4192","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Atypical teratoid/rhabdoid tumors (AT/RT) are malignant central nervous system (CNS) tumors that represent 3% of all pediatric CNS tumors. Majority of cases have SMARCB1 gene mutations and historically carried a poor prognosis.</p><p><strong>Case presentation: </strong>A 9-year-old boy was diagnosed with a third ventricle AT/RT and initially underwent endoscopic surgical biopsy. Subsequent tumor resection was completed using an interhemispheric-transcortical approach.</p><p><strong>Lessons: </strong>Surgical approaches to ventricular system must be tailored to the tumor characteristics on a case-by-case basis. We present a case using a transcortical approach for understanding of the microsurgical anatomy for safe resection of a third ventricle AT/RT.</p>","PeriodicalId":44256,"journal":{"name":"Journal of Neurological Surgery Reports","volume":"86 3","pages":"e187-e188"},"PeriodicalIF":0.7000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483719/pdf/","citationCount":"0","resultStr":"{\"title\":\"Interhemispheric-Transcortical Approach for Resection of an Atypical Teratoid/Rhabdoid Tumor (AT/RT) of the Left Lateral and Third Ventricle.\",\"authors\":\"Douglas Chung, Patrick F O' Brien, Hasan Syed\",\"doi\":\"10.1055/a-2701-4192\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Atypical teratoid/rhabdoid tumors (AT/RT) are malignant central nervous system (CNS) tumors that represent 3% of all pediatric CNS tumors. Majority of cases have SMARCB1 gene mutations and historically carried a poor prognosis.</p><p><strong>Case presentation: </strong>A 9-year-old boy was diagnosed with a third ventricle AT/RT and initially underwent endoscopic surgical biopsy. Subsequent tumor resection was completed using an interhemispheric-transcortical approach.</p><p><strong>Lessons: </strong>Surgical approaches to ventricular system must be tailored to the tumor characteristics on a case-by-case basis. We present a case using a transcortical approach for understanding of the microsurgical anatomy for safe resection of a third ventricle AT/RT.</p>\",\"PeriodicalId\":44256,\"journal\":{\"name\":\"Journal of Neurological Surgery Reports\",\"volume\":\"86 3\",\"pages\":\"e187-e188\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483719/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurological Surgery Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/a-2701-4192\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurological Surgery Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2701-4192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Interhemispheric-Transcortical Approach for Resection of an Atypical Teratoid/Rhabdoid Tumor (AT/RT) of the Left Lateral and Third Ventricle.
Introduction: Atypical teratoid/rhabdoid tumors (AT/RT) are malignant central nervous system (CNS) tumors that represent 3% of all pediatric CNS tumors. Majority of cases have SMARCB1 gene mutations and historically carried a poor prognosis.
Case presentation: A 9-year-old boy was diagnosed with a third ventricle AT/RT and initially underwent endoscopic surgical biopsy. Subsequent tumor resection was completed using an interhemispheric-transcortical approach.
Lessons: Surgical approaches to ventricular system must be tailored to the tumor characteristics on a case-by-case basis. We present a case using a transcortical approach for understanding of the microsurgical anatomy for safe resection of a third ventricle AT/RT.
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