额骨尤文氏肉瘤伴颅内扩张。

IF 0.6 Q4 CLINICAL NEUROLOGY
Journal of Neurological Surgery Reports Pub Date : 2025-07-14 eCollection Date: 2025-07-01 DOI:10.1055/a-2649-0851
Sana Ahuja, Shaivy Malik, Charanjeet Ahluwalia
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引用次数: 0

摘要

尤文氏肉瘤虽然罕见,但主要影响儿童和年轻人,通常表现在长骨上。颅脑受累,特别是在额骨,是非常罕见的,提出诊断和治疗的挑战。细致的病理评估是识别和处理这种非典型表现的关键。一名16岁男性表现为左额叶肿胀和神经系统症状。影像学显示左额骨占位性病变伴颅内延伸。组织病理学根据特征性发现和阳性免疫组织化学标记证实为尤文氏肉瘤。鉴别诊断包括转移性神经母细胞瘤、原始神经外胚层肿瘤和脊索瘤,强调综合评估的重要性。尤文氏肉瘤累及颅骨需要多学科的方法来准确诊断和治疗。本病例强调了临床、放射学和病理评估在识别罕见表现中的重要性。团队之间的协作对于定制管理策略和最佳患者结果至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ewing's Sarcoma of the Frontal Bone with Intracranial Extension.

Ewing's sarcoma, though rare, primarily affects children and young adults, commonly manifesting in long bones. Cranial involvement, particularly in the frontal bone, is exceptionally uncommon, posing diagnostic and therapeutic challenges. Meticulous pathological assessment is crucial for recognizing and managing such atypical presentations. A 16-year-old male presented with left frontal swelling and neurological symptoms. Imaging revealed a space-occupying lesion involving the left frontal bone with intracranial extension. Histopathology confirmed Ewing's sarcoma based on characteristic findings and positive immunohistochemical markers. Differential diagnoses include metastatic neuroblastoma, primitive neuroectodermal tumors, and chordomas, highlighting the importance of comprehensive evaluation. Ewing's sarcoma involving the skull necessitates a multidisciplinary approach for accurate diagnosis and management. This case underscores the significance of clinical, radiological, and pathological assessments in recognizing rare manifestations. Collaboration among teams is crucial for tailored management strategies and optimal patient outcomes.

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