Biomedical Spectroscopy and Imaging最新文献_第2页

Raman spectroscopy applications for the diagnosis and follow-up of type 2 diabetes mellitus. A brief review 拉曼光谱在2型糖尿病诊断及随访中的应用。简要回顾

Biomedical Spectroscopy and Imaging Pub Date : 2020-11-30 DOI: 10.3233/bsi-200207

Alejandra Loyola-Leyva, K. Hernández-Vidales, J. Loyola-Rodríguez, F. J. González

{"title":"Raman spectroscopy applications for the diagnosis and follow-up of type 2 diabetes mellitus. A brief review","authors":"Alejandra Loyola-Leyva, K. Hernández-Vidales, J. Loyola-Rodríguez, F. J. González","doi":"10.3233/bsi-200207","DOIUrl":"https://doi.org/10.3233/bsi-200207","url":null,"abstract":"Background: There is considerable interest in developing faster, less invasive, and more objective techniques to diagnose type 2 diabetes mellits (T2DM). Optical techniques like Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) are efficient, precise, low-cost, portable, and easy to handle, which seem to overcome most of the present difficulties of actual tests for T2DM diagnosis. However, the use of both Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) has been limited for T2DM diagnosis or follow-up. Objective: To gather information regarding the use of Raman spectroscopy and SERS to evaluate the spectra of biofluids (blood components, saliva, and urine) and tissues (skin) as an early diagnostic tool or follow-up for T2DM. Results: Skin and biofluids provide a great amount of information that can be analyzed by Raman spectroscopy and SERS. These optical techniques are excellent for clinical applications and can differentiate people with T2DM from healthy individuals, predict complications arising from T2DM (chronic kidney disease), and might be used to monitor glucose (glycemic control). Conclusion: Raman spectroscopy and SERS are good optical techniques for the diagnosis of T2DM in which sample preparation is not necessary or very simple, non-destructive, non-invasive, relatively fast to acquire, and low-cost.","PeriodicalId":44239,"journal":{"name":"Biomedical Spectroscopy and Imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bsi-200207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42690266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Electron paramagnetic resonance (EPR) spectroscopy: Food, biomedical and pharmaceutical analysis 电子顺磁共振(EPR)光谱:食品、生物医学和药物分析

Biomedical Spectroscopy and Imaging Pub Date : 2020-11-27 DOI: 10.3233/bsi-200206

S. Iravani, G. Soufi

引用次数: 3

ATR-FTIR spectroscopy for virus identification: A powerful alternative 用于病毒识别的ATR-FTIR光谱：一种强大的替代方法

Biomedical Spectroscopy and Imaging Pub Date : 2020-06-09 DOI: 10.3233/bsi-200203

Marfran C. D. Santos, Camilo L. M. Morais, K. M. Lima

{"title":"ATR-FTIR spectroscopy for virus identification: A powerful alternative","authors":"Marfran C. D. Santos, Camilo L. M. Morais, K. M. Lima","doi":"10.3233/bsi-200203","DOIUrl":"https://doi.org/10.3233/bsi-200203","url":null,"abstract":"In pandemic times, like the one we are witnessing for COVID-19, the discussion about new efficient and rapid techniques for diagnosis of diseases is more evident. In this mini-review, we present to the virological scientific community the potential of attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy as a diagnosis technique. Herein, we explain the operation of this technique, as well as its advantages over standard methods. In addition, we also present the multivariate analysis tools that can be used to extract useful information from the data towards classification purposes. Tools such as Principal Component Analysis (PCA), Successive Projections Algorithm (SPA), Genetic Algorithm (GA) and Linear and Quadratic Discriminant Analysis (LDA and QDA) are covered, including examples of published studies. Finally, the advantages and disadvantages of ATR-FTIR spectroscopy are emphasized, as well as future prospects in this field of study that is only growing. One of the main aims of this paper is to encourage the scientific community to explore the potential of this spectroscopic tool to detect changes in biological samples such as those caused by the presence of viruses.","PeriodicalId":44239,"journal":{"name":"Biomedical Spectroscopy and Imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bsi-200203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43952103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 23

Protein adsorption on ZnO films studied by ATR-FTIR spectroscopy 蛋白质在ZnO薄膜上吸附的ATR-FTIR光谱研究

Biomedical Spectroscopy and Imaging Pub Date : 2020-05-15 DOI: 10.3233/bsi-200199

Wolfgang G. Hinze, M. Fallah, K. Hauser

{"title":"Protein adsorption on ZnO films studied by ATR-FTIR spectroscopy","authors":"Wolfgang G. Hinze, M. Fallah, K. Hauser","doi":"10.3233/bsi-200199","DOIUrl":"https://doi.org/10.3233/bsi-200199","url":null,"abstract":". In many scientiﬁc ﬁelds there is a high interest to study molecular adsorption processes on surfaces. The adsorbed molecule can have signiﬁcant impact on the properties of the material under study, for example protein adsorption to inorganic material can enhance its biocompatibility. Attenuated total reﬂection Fourier-transform infrared (ATR-FTIR) spectroscopy is a suitable method to monitor such adsorption processes close to a surface. In this study, ZnO ﬁlms were synthesized on silicon ATR substrates via a mild hydrothermal reaction. The ﬁlms were then characterized by scanning electron microscopy (SEM) and FTIR microscopy. Chemical imaging with FTIR microscopy allowed to analyze the composition of the heterogeneous ﬁlm samples. ATR-FTIR spectroscopy was then applied to investigate the adsorption properties of the ZnO ﬁlms. Protein solutions of bovine serum albumine (BSA) were circulated in a closed cycle over the ZnO ﬁlm and IR spectra were recorded during the adsorption process. A stronger protein adsorption was observed for silicon substrates coated with ZnO than for plain silicon. Furthermore, subsequent ﬂushing with pure water and desorption measurements indicated a stronger protein binding to ZnO than to plain silicon.","PeriodicalId":44239,"journal":{"name":"Biomedical Spectroscopy and Imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bsi-200199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47577645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

MR spectroscopy in Alzheimer’s disease 阿尔茨海默病的磁共振光谱

Biomedical Spectroscopy and Imaging Pub Date : 2020-05-15 DOI: 10.3233/bsi-200194

N. Sheikh-Bahaei

引用次数: 5

Application of tunable quantum cascade lasers to monitor dynamics of bacteriorhodopsin in the mid-IR spectral range 可调谐量子级联激光器在中红外光谱范围内监测细菌视紫红质动力学中的应用

Biomedical Spectroscopy and Imaging Pub Date : 2020-05-15 DOI: 10.3233/bsi-200195

P. Stritt, Michael Jawurek, K. Hauser

引用次数: 6

European Conference on the Spectroscopy of Biological Molecules – Dublin 2019 2019年欧洲生物分子光谱学会议-都柏林

Biomedical Spectroscopy and Imaging Pub Date : 2020-05-15 DOI: 10.3233/bsi-200202

S. Quinn, H. Byrne, P. Haris

{"title":"European Conference on the Spectroscopy of Biological Molecules – Dublin 2019","authors":"S. Quinn, H. Byrne, P. Haris","doi":"10.3233/bsi-200202","DOIUrl":"https://doi.org/10.3233/bsi-200202","url":null,"abstract":"Initiated in 1985, the bi-ennial European Conference on the Spectroscopy of Biological Molecules (ECSBM) has become recognised as one of the leading international conferences at which applications of biomolecular spectroscopy in fundamental scientific research, medical and clinical sciences, and the pharmaceutical industries are explored [1]. The 18th edition of ECSBM took place in the O’Brien Centre for Science, University College Dublin from the 19th – 22nd August 2019, co-chaired by Susan J. Quinn, UCD, and Hugh J. Byrne, TU Dublin. Spectroscopy of Biological Molecules entails the fundamental understanding of biomolecular structure, function and dysfunction, their contributions in organisms, including plants, animals and humans, as well as the development of technologies to monitor their presence, performance, and/or production (e.g. diagnostic imaging, process control). ECSBM provides a platform for a multidisciplinary community, developing a wide range of spectroscopic techniques (IR, Raman, UV-Vis, fluorescence, NMR, EPR) for the investigation of the structures, functions and dysfunctions of biological molecules, exploring the potential applications of the techniques in areas including food and nutrition, biomedical imaging, anticancer research, drug delivery and nano-biotechnology. The scope of the scientific topics covered has recently extended to applications in the fields of biomedical imaging, anticancer research, drug delivery and nano-biotechnology. At the meeting in Dublin, the impact for food science and nutrition was also included within the scope of the programme. In total, the meeting was attended by 177 delegates, from 22 countries, including USA (3) and Brazil (5). The programme entailed 18 oral, and 2 poster sessions. There were a total of 70 oral and 69 poster","PeriodicalId":44239,"journal":{"name":"Biomedical Spectroscopy and Imaging","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3233/bsi-200202","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47960375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Recent advances in LA-ICP-MS for biomedical applications LA-ICP-MS在生物医学应用中的最新进展

Biomedical Spectroscopy and Imaging Pub Date : 2020-01-27 DOI: 10.3233/bsi-200193

L. D. Barbosa, Alessandra Sussulini

引用次数: 3

A Li-Fi based wireless system for surveillance in hospitals 基于Li-Fi的医院无线监控系统

Biomedical Spectroscopy and Imaging Pub Date : 2020-01-27 DOI: 10.3233/bsi-200191

Afaf Mosaif, S. Rakrak

引用次数: 4

Embedded implementation of biomedical applications in heterogeneous systems 异构系统中生物医学应用的嵌入式实现

Biomedical Spectroscopy and Imaging Pub Date : 2020-01-27 DOI: 10.3233/bsi-200192

R. Latif, A. Saddik

引用次数: 2