Electron paramagnetic resonance (EPR) spectroscopy: Food, biomedical and pharmaceutical analysis

IF 0.3 Q4 SPECTROSCOPY

Biomedical Spectroscopy and Imaging Pub Date : 2020-11-27 DOI:10.3233/bsi-200206

S. Iravani, G. Soufi

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引用次数: 3

Abstract

Electron paramagnetic resonance (EPR) spectroscopy can be applied as an effective and non-invasive spectroscopic method for analyzing samples with unpaired electrons. EPR is suitable for the quantification of radical species, assessment of redox chemical reaction mechanisms in foods, evaluation of the antioxidant capacity of food, as well as for the analysis of food quality, stability, and shelf life. It can be employed for evaluating and monitoring the drug release processes, in vitro and in vivo. EPR can be employed for the direct detection of free radical metabolites, and the evaluation of drug release mechanisms from biodegradable polymers; it can be employed for analyzing the drug antioxidant effects. Additionally, spatial resolution can be achieved through EPR-imaging. EPR spectroscopy and imaging have shown diverse applications in food, biomedical and pharmaceutical fields, and also more applications are predictable to emerge in the future. This review highlights recent advances and important challenges related to the application of EPR in food, biomedical and pharmaceutical analysis and assessment.

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电子顺磁共振(EPR)光谱:食品、生物医学和药物分析

电子顺磁共振(EPR)光谱是一种有效的、无创的分析未配对电子样品的光谱方法。EPR适用于自由基种类的定量测定、食品中氧化还原化学反应机制的评价、食品抗氧化能力的评价以及食品质量、稳定性和保质期的分析。它可用于体外和体内药物释放过程的评价和监测。EPR可用于直接检测自由基代谢产物，评价生物降解聚合物的药物释放机制;可用于分析药物的抗氧化作用。此外，通过epr成像可以实现空间分辨率。EPR光谱和成像技术已经在食品、生物医学和制药等领域得到了广泛的应用，未来还将出现更多的应用。本文综述了EPR在食品、生物医学和药物分析与评价方面的最新进展和面临的重要挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biomedical Spectroscopy and Imaging SPECTROSCOPY-

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期刊介绍： Biomedical Spectroscopy and Imaging (BSI) is a multidisciplinary journal devoted to the timely publication of basic and applied research that uses spectroscopic and imaging techniques in different areas of life science including biology, biochemistry, biotechnology, bionanotechnology, environmental science, food science, pharmaceutical science, physiology and medicine. Scientists are encouraged to submit their work for publication in the form of original articles, brief communications, rapid communications, reviews and mini-reviews. Techniques covered include, but are not limited, to the following: • Vibrational Spectroscopy (Infrared, Raman, Teraherz) • Circular Dichroism Spectroscopy • Magnetic Resonance Spectroscopy (NMR, ESR) • UV-vis Spectroscopy • Mössbauer Spectroscopy • X-ray Spectroscopy (Absorption, Emission, Photoelectron, Fluorescence) • Neutron Spectroscopy • Mass Spectroscopy • Fluorescence Spectroscopy • X-ray and Neutron Scattering • Differential Scanning Calorimetry • Atomic Force Microscopy • Surface Plasmon Resonance • Magnetic Resonance Imaging • X-ray Imaging • Electron Imaging • Neutron Imaging • Raman Imaging • Infrared Imaging • Terahertz Imaging • Fluorescence Imaging • Near-infrared spectroscopy.