Mental IllnessPub Date : 2019-01-01Epub Date: 2019-11-04DOI: 10.1108/MIJ-10-2019-0004
Shawna Chan, Robert Bota
{"title":"Personalized TMS: role of RNA genotyping.","authors":"Shawna Chan, Robert Bota","doi":"10.1108/MIJ-10-2019-0004","DOIUrl":"https://doi.org/10.1108/MIJ-10-2019-0004","url":null,"abstract":"<p><strong>Purpose: </strong>Noninvasive brain stimulation (NIBS) such a transcranial magnetic stimulation, intermittent theta burst stimulation, transcranial direct current stimulation and electroconvulsive therapy have emerged as an efficacious and well-tolerated therapy for treatment-resistant psychiatric disorders. While novel NIBS techniques are an exciting addition to the current repertoire of neuropsychiatric therapies, their success is somewhat limited by the wide range of treatment responses seen among treated patients.</p><p><strong>Design/methodology/approach: </strong>In this study, the authors will review the studies on relevant genetic polymorphisms and discuss the role of RNA genotyping in personalizing NIBS.</p><p><strong>Findings: </strong>Genome studies have revealed several genetic polymorphisms that may contribute for the heterogeneity of treatment response to NIBS where the presence of certain single nucleotide polymorphisms (SNPs) are associated with responders versus nonresponders.</p><p><strong>Originality/value: </strong>Historically, mental illnesses have been arguably some of the most challenging disorders to study and to treat because of the degree of biological variability across affected individuals, the role of genetic and epigenetic modifications, the diversity of clinical symptomatology and presentations and the interplay with environmental factors. In lieu of these challenges, there has been a push for personalized medicine in psychiatry that aims to optimize treatment response based on one's unique characteristics.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1108/MIJ-10-2019-0004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38228171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2019-01-01Epub Date: 2019-11-04DOI: 10.1108/MIJ-10-2019-0001
Caroline Lücke, Sylvia Braumandl, Bernhard Becker, Sebastian Moeller, Christina Custal, Alexandra Philipsen, Helge H O Müller
{"title":"Effects of nature-based mindfulness training on resilience/symptom load in professionals with high work-related stress-levels: findings from the WIN-Study.","authors":"Caroline Lücke, Sylvia Braumandl, Bernhard Becker, Sebastian Moeller, Christina Custal, Alexandra Philipsen, Helge H O Müller","doi":"10.1108/MIJ-10-2019-0001","DOIUrl":"https://doi.org/10.1108/MIJ-10-2019-0001","url":null,"abstract":"Purpose The levels of work-related stress and the incidence rates of subsequent related illnesses are increasing in our society, leading to high individual and socioeconomic burdens. Mindfulness training has been shown to be an effective method of improving stress resilience. This paper aims to investigate the efficacy of nature-based mindfulness training in professionals with high levels of work-related stress. Design/methodology/approach In this controlled pilot study, a total of 56 volunteers completed a nature-based mindfulness training progam and were compared to 8 participants (waitlist controls). Psychometric assessments were performed at baseline and after two and four months of training. Findings After two months of training, the scores for self-efficacy, sense of coherence, level of mindfulness and overall psychiatric symptom load had significantly improved in the intervention group, while the control group did not show any significant improvements. A comparison between the intervention and control groups showed a significant difference regarding the sense of coherence only. Research limitations/implications Since this was an exploratory study with a small control group, further studies are needed to verify our findings. Practical implications In conclusion, nature-based mindfulness training seems to be a promising tool for the improvement of resilience and overall psychological health in professionals. Originality/value This was the first study to systematically investigate effects of nature-based mindfulness training in people with high work-related stress.","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1108/MIJ-10-2019-0001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38228173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2019-01-01Epub Date: 2019-11-04DOI: 10.1108/MIJ-10-2019-0007
Marilena Maglia, Roberta Auditore, Stefano Pipitone, Rachele DiPasqua, Lucio Inguscio, Pasquale Caponnetto
{"title":"Combining group psychotherapy and yoga exercises improves quality of life in mental health professionals: a controlled randomized clinical trial.","authors":"Marilena Maglia, Roberta Auditore, Stefano Pipitone, Rachele DiPasqua, Lucio Inguscio, Pasquale Caponnetto","doi":"10.1108/MIJ-10-2019-0007","DOIUrl":"https://doi.org/10.1108/MIJ-10-2019-0007","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the effects of combining 12-week group psychotherapy with yoga exercises on stress perception and quality of life in mental health professionals.</p><p><strong>Design/methodology/approach: </strong>This study was a parallel-arm randomized controlled trial, in which the participants was unaware of which group was the experimental one. Participants involved in our research were assigned to two groups of separate treatment that followed for three months group psychotherapy combined with yoga program for stress management or usual stress coping strategies.</p><p><strong>Findings: </strong>The findings did not reveal a significant difference in stress perception assessed in the two groups either before or after intervention but reveal a significant difference in the quality of life in the two groups before and after the psycho behavioral interventions.</p><p><strong>Originality/value: </strong>The findings did not reveal a significant difference in stress perception assessed in the two groups either before or after intervention but reveal a significant difference in the quality of life in the two groups before and after the psycho behavioral interventions.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1108/MIJ-10-2019-0007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38228170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2018-12-20eCollection Date: 2018-11-06DOI: 10.4081/mi.2018.7901
Zack Zdenek Cernovsky, Paul Victor Fayez Istasy, Yves Bureau, Simon Chiu
{"title":"Scale for retrospective assessment of immediate concussion symptoms.","authors":"Zack Zdenek Cernovsky, Paul Victor Fayez Istasy, Yves Bureau, Simon Chiu","doi":"10.4081/mi.2018.7901","DOIUrl":"https://doi.org/10.4081/mi.2018.7901","url":null,"abstract":"<p><p>The retrospective diagnosis of concussion is often missed by clinicians. We present a brief scale for retrospective assessment of the immediate concussion symptoms (ICS) to facilitate the diagnosis of patients without visible head injury or full loss of consciousness. We administered the scale to 90 survivors of car accidents (mean age 42.0, SD=13.6; 33 males, 57 females) at 2 to 33 months after their accident. Our scale consists of 6 items and these were endorsed by the following % of our respondents: feeling dazed (64.4% of our 90 respondents), stunned (73.3%), confused (70.0%), disoriented (62.2%), dizzy (57.8%), and loss of consciousness (22.2%). The statistical properties of the scale are satisfactory (Cronbach alpha = 0.74). The scale correlates with post-accident insomnia (r=0.28), depression (r=0.29), and also with Rivermead measure of the chronic post-concussion syndrome (r=0.34). The ICS scale could be used as a starting point in longitudinal research with brain imaging procedures to evaluate the stages of recovery from the initial concussion. Attached are the English, Spanish, French, German, Italian, Russian, and Czech versions of our scale.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/mi.2018.7901","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36954081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2018-12-20eCollection Date: 2018-11-06DOI: 10.4081/mi.2018.7812
Pasquale Caponnetto, Marilena Maglia, Roberta Auditore, Marta Bocchieri, Antonio Caruso, Jennifer DiPiazza, Riccardo Polosa
{"title":"Improving neurocognitive functioning in schizophrenia by addition of cognitive remediation therapy to a standard treatment of metacognitive training.","authors":"Pasquale Caponnetto, Marilena Maglia, Roberta Auditore, Marta Bocchieri, Antonio Caruso, Jennifer DiPiazza, Riccardo Polosa","doi":"10.4081/mi.2018.7812","DOIUrl":"https://doi.org/10.4081/mi.2018.7812","url":null,"abstract":"<p><p>Cognitive dysfunctions are a common clinical feature of schizophrenia and represent important indicators of outcome among patients who are affected. Therefore, a randomized, controlled, monocentric, singleblind trial was carried out to compare two different rehabilitation strategies adopted for the restoration and recovery of cognitive functioning of residential patients with schizophrenia. A sample of 110 residential patients were selected and, during the experimental period, a group of 55 patients was treated with sets of <i>domain-specific</i> exercises (SRT+CRT), whereas an equal control group was treated with sets of <i>nondomain- specific</i> exercises (SRT+PBO) belonging to the Cogpack® software. The effects on the scores (between T0 and T1) of the variables <i>treatment</i> and <i>time</i> and of the interaction <i>time X treatment</i> were analyzed: for the total BACS, the <i>main effect</i> of the <i>between-factors</i> variable <i>treatment</i> is statistically significant (F=201.562 P=0.000), as well as the effect of the <i>within-factors</i> variable \"<i>time</i>\" (F=496.68 P=0.000).The interaction of these two factors is also statistically significant (F=299.594 P=0.000). The addition of cognitive remediation therapy (CRT) to a standard treatment of metacognitive training (MCT) resulted in a significant improvement in global neurocognitive functioning and has reported positive effects with regard to the strengthening of <i>verbal</i> and <i>working memory, selective</i> and <i>sustained attention</i> at T1. A relevant result is the statistically significance of \"<i>time X treatment</i>\" for all the tests administered: we can assume that the <i>domain-specific</i> cognitive training amplifies the effects of SRT, as the primary and secondary goals of the present study were achieved.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/mi.2018.7812","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36954075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2018-12-20eCollection Date: 2018-11-06DOI: 10.4081/mi.2018.7881
Teruhisa Komori
{"title":"Extreme prolongation of expiration breathing: Effects on electroencephalogram and autonomic nervous function.","authors":"Teruhisa Komori","doi":"10.4081/mi.2018.7881","DOIUrl":"https://doi.org/10.4081/mi.2018.7881","url":null,"abstract":"<p><p>To clarify the physiological and psychological effects of deep breathing, the effects of extreme prolongation of expiration breathing (Okinaga) were investigated using electroencephalogram (EEG) and electrocardiogram (ECG). Participants were five male Okinaga practitioners in their 50s and 60s. Participants performed Okinaga for 31 minutes while continuous EEG and ECG measurements were taken. After 16 minutes of Okinaga, and until the end of the session, the percentages of theta and alpha 2 waves were significantly higher than at baseline. After 20 minutes, and until the end of the session, the percentage of beta waves was significantly lower than at baseline. The high frequency component of heart rate variability was significantly lower after 12 minutes of Okinaga and lasted until 23 minutes. The low frequency/high frequency ratio was significantly lower after 18 minutes of Okinaga and until the end of the session. Okinaga produced relaxation, suggesting that deep breathing may relieve anxiety. However, study limitations include potential ambiguity in the interpretation of the low frequency/high frequency ratio, the small sample, and the fact that EEG was measured only on the forehead.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/mi.2018.7881","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36954077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2018-12-05eCollection Date: 2018-11-06DOI: 10.4081/mi.2018.7819
Robert Myers
{"title":"Fully-integrated medical home for people with severe and persistent mental illness: A description and outcome analysis of a Medicare Advantage Chronic Special Needs Program.","authors":"Robert Myers","doi":"10.4081/mi.2018.7819","DOIUrl":"https://doi.org/10.4081/mi.2018.7819","url":null,"abstract":"<p><p>People with severe persistent mental illness pose a significant challenge to managed care organizations and society in general. The financial costs are staggering as is the community impact including homelessness and incarceration. This population also has a high incident of chronic comorbid disorders that not only drives up healthcare costs but also significantly shortens longevity. Traditional case management approaches are not always able to provide the intense and direct interventions required to adequately address the psychiatric, medical and social needs of this unique population. This article describes a Medicare Advantage Chronic Special Needs Program that provides a Medical Home, Active Community Treatment, and Integrated Care. A comparison of utilization and patient outcome measures of this program with fee for service Medicare found significant reduction in utilization and costs, as well as increased adherence to the management of chronic medical conditions and preventative services.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2018-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/mi.2018.7819","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36954905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2018-12-05eCollection Date: 2018-11-06DOI: 10.4081/mi.2018.7887
Pasquale Caponnetto
{"title":"Psychological and psychopathological sequelae in cardiovascular acute disease.","authors":"Pasquale Caponnetto","doi":"10.4081/mi.2018.7887","DOIUrl":"https://doi.org/10.4081/mi.2018.7887","url":null,"abstract":"<p><p>The burden of mental illness is profound and growing. Each year, almost one in three adults in the non-institutionalized community has a diagnosable mental or addictive disorder, and this figure climbs to approximately 40% among emergency departments patients. We described the principal cardiovascular acute disease and their emotional and behavioral consequences where psychological intervention could improve the care pathway and clinical outcome. Peer-reviewed articles from Medline, Psycinfo, Web of Science, Scopus, and Cochrane library, about psychological and psychopathological sequelae in cardiovascular acute disease were searched. The psychological and psychopathological sequelae associated to stroke include emotional and behavioral changes and cognitive impairment. Fear, symptoms of depression, anxiety or specific post-traumatic symptoms like intrusions, hyper-arousal and/or cognitive avoidance are common in people suffering of cardiovascular acute disease treated at emergency departments. In emergency departments, health personnel must recognize psychological and psychopathological sequelae in cardiovascular acute disease in order to develop effective interventions for these patients. Identify factors that are associated with both psychological distress and physical distress and promote interventions aimed at reducing psychological distress and improving psychological health empowerment is an important element to consider in order to offer the best care to vulnerable population as that suffering of cardiovascular acute disease.</p>","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2018-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/mi.2018.7887","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36954079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mental IllnessPub Date : 2018-11-06DOI: 10.4081/mi.2018.7806
Bharat R Sampathi
{"title":"Asian mental health and use of drama therapy for acculturative family distancing in immigrant families.","authors":"Bharat R Sampathi","doi":"10.4081/mi.2018.7806","DOIUrl":"https://doi.org/10.4081/mi.2018.7806","url":null,"abstract":"Not available","PeriodicalId":44029,"journal":{"name":"Mental Illness","volume":null,"pages":null},"PeriodicalIF":6.3,"publicationDate":"2018-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4081/mi.2018.7806","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36776155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}