Talanta Open最新文献

{"title":"Geographic determination of Pinus ponderosa using DART TOFMS, ICP-MS, and LIBS handheld analyzer","authors":"Erin R. Price ,&nbsp;Kierra R. Cano ,&nbsp;Caelin P. Celani ,&nbsp;Helder V. Carneiro ,&nbsp;Karl S. Booksh ,&nbsp;James A. Jordan ,&nbsp;Pamela J. McClure ,&nbsp;Megahn H. Pinedo ,&nbsp;Michael E. Ketterer ,&nbsp;Kent M. Elliott ,&nbsp;Tyler B. Coplen ,&nbsp;Edgard O. Espinoza","doi":"10.1016/j.talo.2025.100440","DOIUrl":"10.1016/j.talo.2025.100440","url":null,"abstract":"<div><div>Due to legal requirements on international imports, it is important for law enforcement and regulatory agencies to identify the geographical provenance of timber. Current methods for geographic identification utilize data generated by direct analysis in real time time-of-flight mass spectrometry (DART TOFMS), genetics, and isotope-ratio mass spectrometry (IRMS), but identification methods based on genetics and IRMS data require months to years to create usable databases. This study used machine learning algorithms to compare the results of DART TOFMS, inductively coupled plasma mass spectrometry (ICP-MS), and a handheld laser-induced breakdown spectroscopy (LIBS) analyzer for use in geographic identification of five populations of <em>Pinus ponderosa</em> spaced between 14 to 72 km apart. The results of the study showed comparable performances from machine learning algorithms applied to the ICP-MS and LIBS data with accuracy and kappa values over 90% while the DART TOFMS had an accuracy of 76% and a kappa value of 70%. This study demonstrated that data from the LIBS handheld analyzer is a viable and intriguing alternative to ICP-MS and DART TOFMS analyses in generating training databases and further indicates that trace elemental analysis via ICP-MS is a promising method for generating databases used to identify the origin of timber.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100440"},"PeriodicalIF":4.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative green stability-indicating HPLC method coupled with fluorescence detection for determination of antidiabetic agent canagliflozin","authors":"Nada Nabil ,&nbsp;Ghada A. Sedik ,&nbsp;Hala E. Zaazaa ,&nbsp;Sally S. El-Mosallamy","doi":"10.1016/j.talo.2025.100436","DOIUrl":"10.1016/j.talo.2025.100436","url":null,"abstract":"<div><div>This study exhibits a sustainable, easy, and reliable stability indicating HPLC approach utilizing fluorometric detection for quantification of canagliflozin (CANA) in the presence of its hepatotoxic oxidative degradation product (OXD). The chromatographic separation was accomplished using Symmetry® C18 column (3.5 μm, 4.6 × 100 mm). The mobile phase consists of 0.1 M phosphate buffer pH 2 and ethanol (40:60 v/v) pumped at a flow rate of 1.0 mL/min throughout the run. The eluted peaks were monitored by the fluorescence detector, and the chromatogram was extracted at emission wavelength of 410 nm for CANA and OXD after excitation at 290 nm which was suitable for both CANA and OXD. Performance of the suggested approach was assessed in accordance with ICH guidelines for linearity, accuracy, precision, robustness, detection, and quantitation limits. Linear relationship was achieved in the range of 0.50–10.00 μg/mL and 0.10–2.00 μg/mL for CANA and OXD, respectively with correlation coefficient 0.9999 for both components. The validated method was effectively utilized for the analysis of CANA in its pure form and drug tablets. The environmental sustainability of the suggested approach was evaluated and validated using various tools, including the analytical eco-scale, the Green Analytical Procedure Index (GAPI), and AGREE. Additional applications were employed to evaluate the ideas of 'blueness' and 'whiteness' through the newly developed Blue Applicability Grade Index (BAGI) and Red-Green-Blue 12 (RGB 12) algorithms. The elevated BAGI score (85) signified exceptional applicability, while the RGB12 score (92.2) verified the cost-effectiveness and sustainability of the used approach.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100436"},"PeriodicalIF":4.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Water-stable, sensitive sensors based on lanthanoid ions and a V-shaped linker 4,4′-(hexafluoroisopropylidene)bis(benzoic acid) for the detection of the antibiotic sulfathiazole and potentially hazardous ions in polluted waters","authors":"Denitsa Elenkova,&nbsp;Magdalina Popova,&nbsp;Maria Milanova","doi":"10.1016/j.talo.2025.100434","DOIUrl":"10.1016/j.talo.2025.100434","url":null,"abstract":"<div><div>As long as metal-organic frames, MOFs, are known to possess properties such as good crystallinity, tunable pores, large surface area, they can be considered suitable for sensing of ions and organic molecules in waters. Powder samples with the composition ([Ln₂(FPB)₃]_∞ (Ln = Eu, Tb) and [Eu_0.2Tb_1.8(FPB)₃] are synthesized under solvothermal conditions to be tested as sensors; the fluorinated organic molecule 4,4′-(hexafluoroisopropylidene)bis(benzoic acid) (H₂FPB) is used as a linker. The structure of the synthesized materials is elucidated by powder X-ray diffraction combined with structure having similar composition. Based on the adsorption/desorption isotherms the specific surface area is determined; values of 281, 257, and 286 m²/g for [Eu₂(FPB)₃], [Tb₂(FPB)₃] and [Eu_0.2Tb_1.8(FPB)₃] are attained, important for the Ln-MOFs as sensory materials. By diffuse-reflectance UV–Vis spectroscopy the light absorption of the samples is elucidated as well as by photoluminescence spectroscopy the action of the samples in solid state and in water suspension is followed. The behavior of the samples in media with different acidity is studied showing their stability in acidic and basic solutions in the pH interval 4–9. The luminescence of Ln-MOFs in the presence of different ions and antibiotics is studied in order to evaluate the sensitivity of the samples. Highest sensitivity to the presence of the antibiotic sulfathiazole (SFT) and to the ions Fe (III), Ag (I), Cr (VI), MnO₄^-, C₂O₄^2-, and H₂PO₄^- is detected. The response of the Ln-MOFs to the quenchers SFT, H₂PO₄^- and Cr(III) and Cr (VI) is evaluated based on the Stern-Volmer constants. Both the static and dynamic quenching mechanism are taken into consideration but the static mechanism is evidenced by the Stern Volmer linear dependence of the lifetime by the concentration of the analyte.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100434"},"PeriodicalIF":4.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Galvanic replacement synthesis of Cu@Zeolitic imidazolate framework-8 reinforced hollow fiber for hollow fiber solid-phase microextraction of diazinon and malathion followed by HPLC-UV determination","authors":"Zahra Doraghi ,&nbsp;Heshmatollah Alinezhad ,&nbsp;Milad Ghani","doi":"10.1016/j.talo.2025.100433","DOIUrl":"10.1016/j.talo.2025.100433","url":null,"abstract":"<div><div>This paper represents the synthesis of zinc-based metal-organic framework-8 by the solvothermal method followed by doping of copper (Cu) metal by the purely chemical galvanic replacement method in the synthesized ZIF-8 substrate. Subsequently, the Cu doped ZIF-8 was used as an adsorbent in the hollow fiber solid-phase microextraction (HF-SPME) method for the extraction and determination of organophosphorus pesticides (OPPs), especially diazinon and malathion, from real samples contentiously from tomato, cucumber, apple, and well water. Optimization was done through the Plackett-Burman design and Box-Behnken design. Limits of detection (LODs) of 0.29 µgL⁻¹ and 0.54 µgL⁻¹, while limits of quantification (LOQs) of 0.96 µgL⁻¹ and 1.79 µgL⁻¹ were recorded for diazinon and malathion, respectively. The linear dynamic ranges (LDRs) for both analytes were established as 1–200 µg L⁻¹ and 2–500 µg L⁻¹ with determination coefficients (R²) of 0.9953 for diazinon and 0.9968 for malathion, indicating excellent linearity. The enrichment factors (EFs) were determined to be 152 for diazinon and 146 for malathion. RSDs% were obtained in the range of 4.21 % - 5.78 % for intra-day and 3.53 % - 6.24 % for inter-day precision. The results obtained from the experiments indicate that the developed method has a significant ability to extract and analyze selected analytes in a wide range of real-world samples, which proves the effectiveness and reliability of the method.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100433"},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MIP-based sensing strategies for the diagnosis of prostate and lung cancers","authors":"İnci Uludağ Anıl,&nbsp;Mustafa Kemal Sezgintürk","doi":"10.1016/j.talo.2025.100432","DOIUrl":"10.1016/j.talo.2025.100432","url":null,"abstract":"<div><div>Prostate and lung cancer are among the most prevalent and lethal forms of the disease, and, globally, cancer is a primary cause of mortality. Early diagnosis and the application of precise biomarkers are crucial for prolonging patient lifespan and enhancing quality of life. Molecularly imprinted polymers (MIPs) are synthetic substances capable of selectively identifying and binding specific target molecules. Besides their sensitivity to biomolecules, MIPs offer significant advantages in cancer biomarker detection due to their cost-effectiveness and flexible architectures. MIP-based biosensors designed for the detection of prostate and lung cancer-specific biomarkers provide unique solutions that enhance the diagnostic process and improve its accuracy. This study aims to assess the present state of MIP-based biosensors in the detection of biomarkers for prostate and lung cancer, as well as the potential opportunities provided by this technology. This study will present an overview of potential biomarkers for lung and prostate cancer, clarify the fundamental features of MIPs, and discuss their uses in MIP-based biosensors along with prospective future applications. In this context, our review is aimed to contribute to the development of innovative methods used in early cancer diagnosis.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100432"},"PeriodicalIF":4.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dummy template molecularly imprinted polymer-based sensors in analytical and bioanalytical applications","authors":"Alaa Bedair ,&nbsp;Mahmoud Hamed ,&nbsp;Mahmoud El Hassab ,&nbsp;Reham E. Kannouma ,&nbsp;Reda M. Abdelhameed ,&nbsp;Fotouh R. Mansour","doi":"10.1016/j.talo.2025.100431","DOIUrl":"10.1016/j.talo.2025.100431","url":null,"abstract":"<div><div>Molecular imprinting technology (MIT) is a method for the preparation of artificial receptors for a certain target molecule derived from synthetic polymers. The technique used in synthesizing the molecularly imprinted polymers (MIPs) results in the development of cavities that are properly matched to the exact structure, sizes, and functional groups of the targeted molecule. As a result, these MIPs are capable of specifically identifying the target molecules. In recent decades, it has been widely employed across various fields such as chromatography, antibody and receptor mimetics, solid-phase extraction, biosensors, and others. However, MIPs faced restrictions in selecting the template, mostly because of the insufficient safety and inadequate stability of the compound, making experimental procedures challenging. Furthermore, when utilizing the target analyte as the template, there is a possibility of template leakage or incomplete removal, leading to potential interference with the experimental outcomes. Consequently, the template molecule for MIT may not always be acceptable for direct utilization. The advent of the MIT dummy template offers a convenient and practical solution to prevent these scenarios. As a result, the dummy MIT (DMIT) has emerged as a promising approach. In this review, the roles of DMIT in sensing and biosensing are discussed.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100431"},"PeriodicalIF":4.1,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143644377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cutting-edge design of a novel electrochemical voltammetric nanosensor modified with molecularly imprinted polymer along with multi-walled carbon nanotubes for selective safinamide recognition","authors":"Engy A. Ibrahim ,&nbsp;Samah S. Saad ,&nbsp;Maha A. Hegazy ,&nbsp;Laila E. Abdel Fattah ,&nbsp;Hoda M. Marzouk","doi":"10.1016/j.talo.2025.100428","DOIUrl":"10.1016/j.talo.2025.100428","url":null,"abstract":"<div><div>Safinamide mesylate (SAF) is an innovative adjuvant treatment for managing wearing-off symptoms in Parkinson's disease (PD). Our novel approach involves the development of a differential pulse voltammetric (DPV) technique for SAF determination. This method utilizes a carbon nanocomposite paste electrode that is modified by a molecularly imprinted polymer (MIP) to serve as a recognition element for SAF. Additionally, multi-walled carbon nanotubes (MWCNTs) are incorporated to enhance the electrode's sensitivity. The MIP was subjected to a thorough characterization process, including analysis of rebinding, differential scanning calorimetry, field emission scanning electron microscopy, and Fourier-transform infrared spectroscopy. The cavities of the MIP recognize and bind to the medication, functioning as reliable host-tailored artificial receptors. The resulting modified electrode functions as a voltammetric sensor, enabling the nano detection of SAF. The fabricated MIP/MWCNTs-CPE demonstrates a linear range from 0.3 to 22.0 μg/mL and excellent sensitivity, with a limit of detection (LOD) of 0.079 μg/mL. According to ICH guidelines, the enhanced method has been validated for quality control testing on the pharmaceutical product and spiked human plasma. The proposed method was found to be practical, reliable, cost-effective, and efficient means of estimating the investigated drug. The method's sustainability was assessed by analyzing its scores for greenness, blueness, and whiteness. Therefore, this method has the potential to be a long-term, practical analytical tool for in vitro studies and quality control laboratories.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100428"},"PeriodicalIF":4.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microwave-assisted synthesis of watercress-derived N,S-doped carbon dots for sensitive spectrofluorimetric determination of rifaximin antibiotic: Greenness, blueness, and whiteness assessment","authors":"Rehab H. Elattar ,&nbsp;Asmaa Kamal El-Deen ,&nbsp;Randa A. Abdel Salam ,&nbsp;Ghada M. Hadad ,&nbsp;Anmar Anwar Khan ,&nbsp;Galal Magdy","doi":"10.1016/j.talo.2025.100426","DOIUrl":"10.1016/j.talo.2025.100426","url":null,"abstract":"<div><div>A rapid microwave-assisted method was developed for synthesizing watercress-derived nitrogen and sulfur carbon dots (N,S-CDs) in just one minute using thiourea as a nitrogen and sulfur source and watercress as a green carbon source. Different spectroscopic and microscopic techniques were used to characterize the N,S-CDs. The synthesized N,S-CDs exhibited maximum fluorescence emission at 386 nm after being excited at 320 nm. Rifaximin (RFX) could quench the native fluorescence of the N,S-CDs quantitatively based on the inner filter effect (IFE) and static quenching mechanisms. The results revealed a good linearity over the range of 0.2–30.0 µg/mL, with a correlation coefficient of 0.9996. The developed method demonstrated excellent accuracy, with recovery values between 99.16 % and 99.97 %, and good precision, as the %RSD values were ≤ 1.3 % for both intra-day and inter-day precision. The detection and quantitation limits were found to be 0.06 µg/mL and 0.19 µg/mL, respectively. The method was successfully applied for determining RFX in its tablets with high selectivity. The developed method produced comparable results to those obtained by the published HPLC method in terms of precision and accuracy. Finally, the developed method demonstrated excellent green, blue, and white characteristics based on the results obtained <em>via</em> the analytical Eco-scale, AGREE, MoGAPI, BAGI, and RGB12 tools. The suggested method offers a sensitive, fast, and eco-friendly spectrofluorimetric methodology for estimating the RFX without requiring hazardous organic solvents or complicated equipment.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100426"},"PeriodicalIF":4.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double-reverse-signal ratiometric fluorescence probe for residual determination of chlorpyrifos pesticide in surface water based on scalable upcycling of rice straw to luminescent CQDs via energy-efficient alkali treatment","authors":"Rania El-Shaheny ,&nbsp;Lateefa Al-Khateeb ,&nbsp;Mahmoud El-Maghrabey ,&nbsp;Galal Magdy ,&nbsp;Heba M. Hashem","doi":"10.1016/j.talo.2025.100427","DOIUrl":"10.1016/j.talo.2025.100427","url":null,"abstract":"<div><div>A smart, green, practical, and simple method has been developed for the preparation of blue emissive carbon dots (RS-CDs). The developed synthesis protocol is accomplished at room temperature via an instrument-free approach using the alkali treatment of rice straw. The furnished RS-CDs were thoroughly characterized via transmission electron microscopy, energy-dispersive X-ray spectrometry, x-ray photoelectron spectroscopy, UV-Vis, and fluorescence spectroscopy. The RS-CDs exhibited excellent performance as a double-response-reverse type ratiometric fluorescence probe for the widely used insecticide chlorpyrifos. By systematically investigating and optimizing the experimental conditions, a new sensitive and accurate RS-CDs-based ratiometric fluorescence probe was constructed, taking advantage of the simultaneous decrease of emission intensity at 396 nm and increase of a new emission peak at 340 nm upon adding chlorpyrifos. The ratio of fluorescence intensity at 340 and 396 nm (F_340/396) showed excellent correlation to chlorpyrifos concentration over the range of 7.1 – 142.4 µM with a detection limit of 2.3 µM. Excellent recovery percentages have been obtained for chlorpyrifos in tap, river, and irrigation water, 102.24 ± 1.52, 104.33 ± 1.79, and 100.43 ± 2.51 %, respectively. The presented approach is the first to convert agricultural waste into nanomaterial by room temperature treatment. Boosting the value of rice straw via upcycling to luminescent CDs is one of the things that helps sustain the practice in limited-income labs. The environmental impact, greenness, practicality, economical, and analytical attributes of the developed method have been positively confirmed by different recent metrics.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100427"},"PeriodicalIF":4.1,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143578571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of eco-friendly sensitive HPLC method for determination of Letrozole and assessment of validation","authors":"Hayam Mahmoud Lotfy ,&nbsp;Asena Ayse Genc ,&nbsp;M. Soner Bay ,&nbsp;Gizem Tiris ,&nbsp;Reem H. Obaydo ,&nbsp;Nevin Erk","doi":"10.1016/j.talo.2025.100425","DOIUrl":"10.1016/j.talo.2025.100425","url":null,"abstract":"<div><div>The greening of analytical methods has gained interest in the field of quantitative analysis to reduce environmental impact and improve analyst's safety and health. For postmenopausal women with hormone-responsive advanced breast cancer, Letrozole (LTZ) has been a standard first-line endocrine therapy A green HPLC method was developed, optimized, validated, and applied for quantification of the LTZ in tablets. Experiments were conducted on the Inertsil ODS- 3® C18 (5 µm, 150 × 4.6 mm). An isocratic elution was applied using a mobile phase consisting of ethanol: water (50:50, v/v). A wavelength of 230.0 nm was chosen for the analysis. An experiment was finished 3.0 mins. Calibration graphs for each drug were rectilinear in the range of 0.1 – 40.0 µg/mL. Validation studies were carried out based on International Conference on Harmonization (ICH) recommendations. The student (t) test for means and the (F) test for standard deviations were used to compare the results. In this study, we utilized the ChlorTox Scale, Greenness Index, AGREE, GAPI, and NQS Indicator to comprehensively evaluate the environmental, safety, and sustainability aspects of analytical methodology, aligning our approach with the United Nations Sustainable Development Goals (SDGs). It can be applied to quality control, bioequivalence studies, and routine analysis.</div></div>","PeriodicalId":436,"journal":{"name":"Talanta Open","volume":"11 ","pages":"Article 100425"},"PeriodicalIF":4.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143553000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}