{"title":"Use of a discrete electro-oculographic control system with and without oscillatory motion of the head","authors":"D.H. Bahi, J. LaCourse, F.C. Hludik","doi":"10.1109/NEBC.1991.154614","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154614","url":null,"abstract":"The effectiveness of the discrete electrooculographic control system (DECS) and various methods of its use are studied. This device utilizes the dipole present in the eye to emulate a standard computer input device. Initial tests of the DECS system parameters show that this device may be useful as an input device for persons with some degree of uncontrollable vibration when resting or moving. Though somewhat cumbersome in comparison to a conventional joystick or mouse, the DECS is a novel input device for any user.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128214417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple modal frequency analysis for monitoring of bone healing","authors":"M. Nowak, M. N. Selamat, N. Baharin, W. Rahman","doi":"10.1109/NEBC.1991.154656","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154656","url":null,"abstract":"Multiple frequency modes were examined in an analogy of tibial bone healing. Wooden dowels were examined by striking with an instrumented hammer and monitoring an accelerometer at the other end of the rod. Three frequency modes were determined for intact rods, along with rods with partial transverse cuts (1/4, 1/2, 3/4 diameter depths). Fully cut rods were repaired with glue or foam to simulate complete and incomplete bone healing. The use of multiple frequency modes was determined to be a better predictor of cut bone than the first mode alone. Repaired rods displayed similar results. This work demonstrates the validity of frequency examination beyond simple first mode determination for the analysis of bone healing. Implications and future work are discussed.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126807221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Lader, C. Tamanaha, J. Li, N. W. Downer, H. Smith, Y. Mendelson, R. Peura
{"title":"An investigative study of membrane-based biosensors","authors":"A. Lader, C. Tamanaha, J. Li, N. W. Downer, H. Smith, Y. Mendelson, R. Peura","doi":"10.1109/NEBC.1991.154670","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154670","url":null,"abstract":"A system for incorporating naturally occurring membrane-based biological recognition elements into surface structures has been investigated. Alkylsilane molecules were covalently bound to the surface of a silicon/silicon dioxide (Si/SiO/sub 2/) electrode as one half of a bilayer membrane mimetic structure. Detergent dialysis was then used to reconstitute lipids and proteins into the other half of this structure.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125626697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanism of the voltage-induced conductance change in the Na channel","authors":"H. R. Leuchtag","doi":"10.1109/NEBC.1991.154632","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154632","url":null,"abstract":"A mechanism proposed for the voltage-dependent sodium channel postulates solid-state Na/sup +/ conduction through the polypeptide structure. Ion conduction is assumed to be state solid-state, through the protein subunits of the channel, rather than aqueous, through a hypothetical pore. The channel conformational change is taken to be a phase transition, with the closed state ferroelectric and the open state superionically conducting. This hypothesis is consistent with the known experimental properties of the channel, and it explains channel properties that current theories are unable to explain-in particular, the initiation of a sodium current by a membrane depolarization. The hypothesis explains channel hysteresis, heat and cold block, magnitude of surface charge, and other observed properties.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131904733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. C. Johnson, M. Krag, D. Pflaster, L. Haugh, M. Pope
{"title":"A device for measuring soft tissue pressure: application to human intervertebral disc and bovine tendon","authors":"C. C. Johnson, M. Krag, D. Pflaster, L. Haugh, M. Pope","doi":"10.1109/NEBC.1991.154682","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154682","url":null,"abstract":"A needle mounted strain gauge pressure sensor has been developed that has proven to be both accurate and reliable. It is a resistive strain gauge mounted on a pressure diaphragm which is exposed to pressure through a silicone window. The transducer is used in a Wheatstone bridge configuration and incorporates a dummy resister for temperature compensation. The transducer cable also contains an excitation voltage limiting circuit for protection of the sensor. The authors used a Measurements Group model 2100 amplifier to provide an excitation voltage of 3 V DC and a gain of 300. Although the sensor's maximum deviation from linearity is over 5%, its curve can be fitted by a quadratic to within 0.4% error. Its use for intradiscal pressure measurements appears to be very satisfactory. Measurement of tendon and ligament tensile force was also good.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133034132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spectral distribution of current during electrosurgery","authors":"S. Selikowitz, J. Lacourse","doi":"10.1109/NEBC.1991.154672","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154672","url":null,"abstract":"A spectrum analysis of current in axial body structures during electrosurgery, utilizing a canine model in a simulated transurethral resection, has revealed a shift to lower frequency peaks as the power levels of the generator were increased. The authors verified prior investigations in the time domain, where greater collective current levels were observed in arteries, followed sequentially by vein, muscle, and nerve. Arterial/venous current ratios were in the range of 2:1 in the extremities. The levels of current in cylindrical structures were proportional to cross-sectional area and appeared to be conduit dependent. Great vessels, such as the aorta and the heart, appear to act as sinks for large amounts of current, sometimes exceeding 500 mA total with 3000 mA noted at peaks 40 Hz separate from the generator center frequency at 680 kHz. The cardiac muscle, likewise, contains substantial current at practically all frequencies measured within a 100 kHz range of center, and even beyond.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115467210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modeling amplitude-modulated (AM) tone encoding behavior of cochlear nucleus neurons","authors":"S. Ghoshal, D.O. Kim, R. Northrop","doi":"10.1109/NEBC.1991.154553","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154553","url":null,"abstract":"An attempt was made to understand the mechanisms underlying the response of the cochlear nucleus (CN) neurons, specifically the choppers, to the AM tone. The AM tone excitation via the auditory nerve fibers was modeled as a combination of DC, AC, and a zero-mean Gaussian noise current at the soma of the model neuron. The DC represents the high frequency carrier beyond the neuron's phase-locking limit and the AC represents the envelope. With a systematic variation of DC, AC, and noise amplitudes, the stellate cell models could reproduce the low-pass and band-pass modulation transfer functions (MTFs) and intrinsic oscillations (IOs). A close correlation was observed between the IO frequency and the best envelope frequency in the stellate cell models.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"217 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122090058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impedance mapping of myocardial tissue during ischemia","authors":"M. Mirotznik, M. Fallert, D. Bogen, K. Foster","doi":"10.1109/NEBC.1991.154640","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154640","url":null,"abstract":"An impedance measurement system was developed for measuring myocardial tissue impedance (MTI) during ischemia in sheep and epicardial mapping system was developed that used a four electrode method with cardiac cycle gated and signal averaged measurements. After 60 minutes of ischemia, MTI increased by an average of 200% compared to non-ischemic tissue. A myocardial tissue model was developed which suggests that changes in MTI are primarily due to changes in cellular volume fraction.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130537285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New configurations of the electrocautery hemostat","authors":"R. Aston, E. Lottick","doi":"10.1109/NEBC.1991.154574","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154574","url":null,"abstract":"Several configurations of the electrocautery hemostat (ECH) are investigated. It is shown that a displaced blade retains the grasping feature, as it improves the blade sharpness, resulting in a reduction of tissue damage. A properly configured ECH can be made sharper than a standard commercially available electrosurgical unit (ESU) blade. It is concluded that the smallest area among the hemostat blades would have superior cutting capabilities. Tissue damage by an ECH can be decreased at a given force on the blade, by reducing the thickness of the blade in contact with the tissue. Grinding standard ESU blades to a finer edge makes them sharper and would reduce tissue damage, since they require less power for a given operation.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131310068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Sacristán, R. Peura, A. Shahnarian, R. Fiddian-Green
{"title":"Development of a flexible PCO/sub 2/ microsensor for gastrointestinal pHi monitoring","authors":"E. Sacristán, R. Peura, A. Shahnarian, R. Fiddian-Green","doi":"10.1109/NEBC.1991.154620","DOIUrl":"https://doi.org/10.1109/NEBC.1991.154620","url":null,"abstract":"The intramucosal pH (pHi) is indirectly determined by measuring the PCO/sub 2/ in the lumen of the gut, and the bicarbonate ion concentration in an arterial blood sample; the pHi is then calculated using the Henderson-Hasslebach equation. A microsensor is developed to measure the intramural PCO/sub 2/. The microsensor is designed as part of a flexible catheter for insertion into the colon or stomach. The sensor satisfied all accuracy and performance criteria after being tested in vivo. The in vivo performance was validated in pigs, with induced intestinal ischemia by comparing the sensor pHi measurements to those determined using a balloon tanometer and a needle pH electrode directly placed in the mucosal tissue.<<ETX>>","PeriodicalId":434209,"journal":{"name":"Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1991-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121198712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}