膜基生物传感器的调查研究

Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference Pub Date : 1991-04-04 DOI:10.1109/NEBC.1991.154670

A. Lader, C. Tamanaha, J. Li, N. W. Downer, H. Smith, Y. Mendelson, R. Peura

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引用次数: 3

摘要

将天然存在的基于膜的生物识别元素纳入表面结构的系统已经被研究。烷基硅烷分子共价结合在硅/二氧化硅(Si/SiO/sub 2/)电极表面，作为双层膜模拟结构的一半。然后使用洗涤剂透析将脂质和蛋白质重构为该结构的另一半。

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An investigative study of membrane-based biosensors

A system for incorporating naturally occurring membrane-based biological recognition elements into surface structures has been investigated. Alkylsilane molecules were covalently bound to the surface of a silicon/silicon dioxide (Si/SiO/sub 2/) electrode as one half of a bilayer membrane mimetic structure. Detergent dialysis was then used to reconstitute lipids and proteins into the other half of this structure.<>

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Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference

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