An investigative study of membrane-based biosensors

Abstract

A system for incorporating naturally occurring membrane-based biological recognition elements into surface structures has been investigated. Alkylsilane molecules were covalently bound to the surface of a silicon/silicon dioxide (Si/SiO/sub 2/) electrode as one half of a bilayer membrane mimetic structure. Detergent dialysis was then used to reconstitute lipids and proteins into the other half of this structure.<>