Journal of Dermatology & Dermatologic Surgery-JDDS最新文献

{"title":"Localized lepromatous leprosy","authors":"Khalid M. Alwunais","doi":"10.1016/j.jdds.2015.03.005","DOIUrl":"10.1016/j.jdds.2015.03.005","url":null,"abstract":"<div><p>Lepromatous leprosy is usually generalized at diagnosis and may consist of erythematous macules, papules and nodules containing abundant <em>Mycobacterium leprae</em> and affecting wide spread areas of the skin. Localized skin involvement by lepromatous leprosy is rare.</p><p>In this report a 37<!--> <!-->year old Filipino man presented with erythematous lesions localized on the right elbow and left knee for 9<!--> <!-->months associated with diminished sensation.</p><p>Clinically the patient presented with localized lesions mimicking tuberculoid leprosy, although a biopsy from the lesion revealed lepromatous type leprosy.</p><p>A skin biopsy showed numerous acid fast bacilli and fat laden macrophages with a paucity of lymphocytes, Slit skin smear examination for <em>M. leprae</em> from the lesion revealed a Bacteriological Index (BI) of 6+ which is compatible with lepromatous leprosy.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 133-135"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73509608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subcorneal pustular dermatosis in a 7-year old Saudi child: A case report and review of the literature","authors":"Ali Al Ameer,&nbsp;Abdullah Al Salman,&nbsp;Ibraheem Al Braheem,&nbsp;Yosif Al Marzoq,&nbsp;Mariam Imran","doi":"10.1016/j.jssdds.2014.01.001","DOIUrl":"10.1016/j.jssdds.2014.01.001","url":null,"abstract":"<div><p>Subcorneal pustular dermatosis (SCPD) also known as Sneddon–Wilkinson disease (<span>Sneddon and Wilkinson, 1956</span>) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence (<span>Johnson and Cripps, 1974</span>). The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis. In this paper we present the case of a 7-years-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Oral and topical corticosteroid has been successfully used in the treatment of the disease.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 136-139"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jssdds.2014.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73095132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatological effects of Nigella sativa","authors":"Salih H.M. Aljabre ,&nbsp;Omar M. Alakloby ,&nbsp;Mohammad A. Randhawa","doi":"10.1016/j.jdds.2015.04.002","DOIUrl":"10.1016/j.jdds.2015.04.002","url":null,"abstract":"<div><p><em>Nigella sativa</em> seed, commonly known as black seed, has been employed as a natural remedy for many ailments for centuries in many cultures. It contains many active components including thymoquinone, thymohydroquinone, dithymoquinone, thymol, carvacrol, nigellimine, nigellicine, nigellidine and alphahederin. It was reported to possess numerous pharmacological effects related to several organs of the body. In this article, the literature pertaining to dermatological effects of <em>N. sativa</em> is reviewed. To the best of our knowledge this is the first review in this subject and we expect it stimulates further studies on the dermatological effects and application of <em>N. sativa</em>.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 92-98"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82975712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of contact dermatitis","authors":"Sultan T. Al-Otaibi,&nbsp;Hatem Ali M. Alqahtani","doi":"10.1016/j.jdds.2015.01.001","DOIUrl":"10.1016/j.jdds.2015.01.001","url":null,"abstract":"<div><p>Skin disorders compromise more than 35% of all occupationally related disorders. Most of these are contact dermatitis as a result from contact with a chemical substance. Contact dermatitis can be either irritant or allergic type. Each type has a different mechanism while the clinical presentation is the same. Management of contact dermatitis must include both medical treatment and workplace modifications as appropriate to reduce exposure to the causative agents. Physicians should be aware of this preventable medical condition.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 86-91"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81952257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum prolactin levels in dermatological diseases: A case–control study","authors":"Nadia Abdalhafid Elsherif ,&nbsp;Abdalla I. El-Sherif ,&nbsp;Salwa A. El-Dibany","doi":"10.1016/j.jdds.2015.03.002","DOIUrl":"10.1016/j.jdds.2015.03.002","url":null,"abstract":"<div><h3>Background</h3><p>Recent lines of evidence suggest that prolactin (PRL) as a neurohormone may play a role in the activity of psoriasis and some other immune-mediated diseases. Our aim was to evaluate the correlation between serum PRL levels and severity of psoriasis, vitiligo and alopecia areata.</p></div><div><h3>Patients and methods</h3><p>We performed a case–control study on 100 subjects: 75 patients; suffering from psoriasis, vitiligo and alopecia areata; 25 patients in each group and 25 age- and sex-matched healthy controls.</p></div><div><h3>Results</h3><p>Serum prolactin levels were significantly high in all three dermatological diseases in comparison with the control group (<em>P</em> <!-->=<!--> <!-->0.000). The mean<!--> <!-->±<!--> <!-->SD of the serum prolactin levels was 21.8<!--> <!-->±<!--> <!-->11.5<!--> <!-->ng/ml, 16.9<!--> <!-->±<!--> <!-->6.8<!--> <!-->ng/ml, and 16.6<!--> <!-->±<!--> <!-->8.0<!--> <!-->ng/ml in patients with alopecia areata, psoriasis and vitiligo respectively. Moreover, the serum prolactin levels in patients with alopecia areata and psoriasis were significantly correlated with disease severity (<em>P</em> <!-->&lt;<!--> <!-->0.05), however no statistically significant correlation was noted between vitiligo severity and serum prolactin levels (<em>P</em> <!-->&gt;<!--> <!-->0.05).</p></div><div><h3>Conclusions</h3><p>Prolactin may play a role in the pathogenesis of alopecia areata, psoriasis, and vitiligo; and may serve as a biological marker of disease activity in patients with psoriasis and alopecia areata.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 104-107"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80226612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ciliary phthiriasis: Dermoscopic diagnosis","authors":"Siham Lakjiri,&nbsp;Salim Gallouj,&nbsp;Fatima Zahra Mernissi","doi":"10.1016/j.jdds.2014.12.001","DOIUrl":"10.1016/j.jdds.2014.12.001","url":null,"abstract":"<div><p>Phthiriasis palpebrarum (lice infestation of eyelid) is a rarely reported disorder. It may present as blepharoconjunctivitis, and is therefore often neglected. We present a 36<!--> <!-->year-old female who suffered itching and irritation at eyelids. A careful examination of the eyelids objectified blackish granules of cilia. Dermoscopic examination revealed the presence of nits attached to the eyelashes with tiny brownish punctuation found on the skin, which they could easily recognize as adult lice that were mobilized around the eyelids. She was successfully treated with oral ivermectin. After clinical and dermoscopical control, no more lice or nits were present in the patient. This report emphasizes the importance of the correct diagnosis and management of this disease, and the interest of dermoscopy in the diagnosis and treatment evaluation of phthiriasis palpebrarum.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 130-132"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2014.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90808248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psoriasis induced by Interferon alfa-2a and ribavirin in a patient followed for hepatitis C","authors":"N. Amraoui ,&nbsp;S. Gallouj ,&nbsp;N. Oubelkacem ,&nbsp;W. Bono ,&nbsp;F. Mernissi","doi":"10.1016/j.jdds.2015.01.002","DOIUrl":"10.1016/j.jdds.2015.01.002","url":null,"abstract":"<div><p>In patients suffering from chronic hepatitis C, Interferon (INF) associated with ribavirin therapy can induce various side effects involving the skin. Our case describes the clinical course of a patient with chronic hepatitis C treated with pegylated α2 INF plus ribavirin. After 6<!--> <!-->weeks of therapy he developed psoriasis. However, given the progressive improvement of his transaminase levels and viral load decrease, we continued the protocol of the treatment and we started topical calcipotriol/betamethasone dipropionate ointment for psoriasic lesions. After this, the psoriasis improved in a slow but comprehensive manner. This paper suggests that physicians should keep in mind the possibility of the onset of psoriasis as a side effect of INF treatment for chronic hepatitis C.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 126-129"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91424076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital self-healing reticulohistiocytosis (Hashimoto–Pritzker syndrome)","authors":"Ali M. Al Ameer,&nbsp;Abdullah Al Salman,&nbsp;Yosif Al Marzoq,&nbsp;Abdulmohsin Al Hajri,&nbsp;Ibraheem Al Omran,&nbsp;Salha Al Dossari,&nbsp;Mariam Imran","doi":"10.1016/j.jdds.2014.03.002","DOIUrl":"10.1016/j.jdds.2014.03.002","url":null,"abstract":"<div><p>A case of congenital self-healing reticulohistiocytosis in an otherwise healthy newborn boy is presented. Erythematous papules covered by scales on the groin and single nodule on the left side of the forehead, which disappeared spontaneously within four months. Clinical features, histological and immunohistochemical findings are described. Up to our knowledge this is the first case described in Saudi Arabia.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 1","pages":"Pages 55-57"},"PeriodicalIF":0.4,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2014.03.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78503069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinico-epidemiological profile of vitiligo patients in Najran Region, Saudi Arabia","authors":"Hamad Ayed AL Fahaad","doi":"10.1016/j.jdds.2014.05.001","DOIUrl":"10.1016/j.jdds.2014.05.001","url":null,"abstract":"<div><h3>Objectives</h3><p>To assess the prevalence of vitiligo among patients with dermatological diseases in Najran, South-Western Saudi Arabia, and to explore the epidemiological profile of vitiligo patients in the region.</p></div><div><h3>Materials and methods</h3><p>This single-observer, cross-sectional, descriptive study was conducted over a period of six months by recording the clinico-epidemiological profile of 101 vitiligo cases. The patients were diagnosed by history, clinical findings and Wood’s lamp at the dermatology out-patient clinic in the King Khalid Hospital, Najran. Demographic and clinical data of the patients were collected using a pre-structured data collection form. Pearson <em>χ</em>² test and Fisher’s exact test were used to explore the significant association of selected characteristics with ‘type’ and ‘site’ of vitiligo among the study-patients.</p></div><div><h3>Results</h3><p>The estimated prevalence of vitiligo cases among the dermatology out-patient clinic attendees was 1.98%. Vitiligo patients were predominantly males (57.4%), Saudis (93.1%), housewives (24.8%), and non-smokers (95%). The mean age of the study-patients was 34.33<!--> <!-->±<!--> <!-->15.82 years, and the highest number (28.7%) belonged to the age group ‘31–40<!--> <!-->years’. Of the cases, 5.9% had a family history of vitiligo, 6.9% had diabetes mellitus, and 4% were suffering from anemia. Approximately 99% of the patients or the parents of the pediatric patients were affected by either moderate or mild stress due to vitiligo. Highest number (48.5%) of the patients presented localized type of vitiligo, whereas 22.8% had acrofacial, 20.8% showed vulgaris, 5% presented universal, 2% had acral, and 1% experienced segmental type of vitiligo. Around one-fourth (25.7%) of the patients had vitiligo only on their extremities, while remaining cases experienced vitiligo on the other parts of their body. Median duration of the disease was 4<!--> <!-->years (IQR: 2–7.5<!--> <!-->years). The type of vitiligo showed a significant association with sex, underlying diseases, and stress grade (<em>p</em> <!-->&lt;<!--> <!-->0.05), while the site of vitiligo was significantly associated with sex and stress grade (<em>p</em> <!-->&lt;<!--> <!-->0.05).</p></div><div><h3>Conclusion</h3><p>Localized vitiligo was found to be the most common type of vitiligo prevalent in the Najran Region. Because stress has a role in provoking vitiligo, community based awareness programs should be developed to reduce the stress in order to control and modify the course of the disease.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 1","pages":"Pages 31-35"},"PeriodicalIF":0.4,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2014.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79701460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bowen’s disease in a patient with Primary Sjögren’s syndrome: A case report and a review of the literature","authors":"Besma Ben Dhaou,&nbsp;Imen Rachdi,&nbsp;Rym Ben Mously,&nbsp;Zohra Aydi,&nbsp;Fatma Daoud,&nbsp;Lilia Baili,&nbsp;Insaf Mokhtar,&nbsp;Fatma Boussema","doi":"10.1016/j.jdds.2014.05.002","DOIUrl":"10.1016/j.jdds.2014.05.002","url":null,"abstract":"<div><p>A rare case of Bowen’s disease (BD) in a patient with Primary Sjögren’s syndrome is reported. A 42-year-old woman suffering from Primary Sjögren’s syndrome retained on the basis of clinical and serological findings, was admitted 3<!--> <!-->years later for genital bleeding. The diagnosis of Bowen’s disease was established by clinical and histolopathological examination. Classical association of lymphoma and Sjögren’s syndrome is described, but to the best of our knowledge, it is the second report of BD associated to Sjögren’s syndrome in published literature. A common physio-pathological etiology cannot be excluded.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 1","pages":"Pages 62-65"},"PeriodicalIF":0.4,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2014.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75990605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}