Ali Al Ameer, Abdullah Al Salman, Ibraheem Al Braheem, Yosif Al Marzoq, Mariam Imran
{"title":"Subcorneal pustular dermatosis in a 7-year old Saudi child: A case report and review of the literature","authors":"Ali Al Ameer, Abdullah Al Salman, Ibraheem Al Braheem, Yosif Al Marzoq, Mariam Imran","doi":"10.1016/j.jssdds.2014.01.001","DOIUrl":null,"url":null,"abstract":"<div><p>Subcorneal pustular dermatosis (SCPD) also known as Sneddon–Wilkinson disease (<span>Sneddon and Wilkinson, 1956</span>) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence (<span>Johnson and Cripps, 1974</span>). The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis. In this paper we present the case of a 7-years-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Oral and topical corticosteroid has been successfully used in the treatment of the disease.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 136-139"},"PeriodicalIF":0.2000,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jssdds.2014.01.001","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Dermatology & Dermatologic Surgery-JDDS","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210836X14000025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 1
Abstract
Subcorneal pustular dermatosis (SCPD) also known as Sneddon–Wilkinson disease (Sneddon and Wilkinson, 1956) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence (Johnson and Cripps, 1974). The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis. In this paper we present the case of a 7-years-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Oral and topical corticosteroid has been successfully used in the treatment of the disease.
角膜下脓疱性皮肤病(SCPD)也被称为Sneddon - Wilkinson病(Sneddon and Wilkinson, 1956)是一种罕见的、良性的、慢性的、无菌的脓疱性皮肤病,通常发生在中年或老年妇女;它在儿童和青少年时期很少见(Johnson and Cripps, 1974)。原发性病变为豌豆大小的脓疱,典型描述为半脓疱,半透明的松弛性水泡。组织学上最重要的特征是角膜下中性粒细胞的积聚,没有海绵状病或棘层松解。在本文中,我们提出了一个7岁的男孩诊断为SCPD基于特点的临床和组织学特征。口服和外用皮质类固醇已成功地用于治疗这种疾病。