Journal of Dermatology & Dermatologic Surgery-JDDS最新文献_第7页

Microcystic adnexal carcinoma: A focused review and updates 微囊性附件癌:重点回顾和最新进展

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2015.03.001

Nouran S. Hamed , Amor Khachemoune

引用次数: 12

Interleukin 17 deficiency and implications in cutaneous and systemic diseases 白细胞介素17缺乏及其对皮肤和全身疾病的影响

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2015.03.004

Elizabeth Z. Welch , Kathryn L. Anderson , Steven R. Feldman

{"title":"Interleukin 17 deficiency and implications in cutaneous and systemic diseases","authors":"Elizabeth Z. Welch , Kathryn L. Anderson , Steven R. Feldman","doi":"10.1016/j.jdds.2015.03.004","DOIUrl":"10.1016/j.jdds.2015.03.004","url":null,"abstract":"<div><h3>Background</h3><p>IL17-targeted therapeutics are being developed to treat psoriasis. IL17 is involved in the pathogenesis of many diseases, and the implications of IL17 blockade are not yet well characterized.</p></div><div><h3>Objective</h3><p>To review the implications of IL17 deficiency to determine potential implications of IL17 blockade.</p></div><div><h3>Methods</h3><p>PubMed was searched for articles related to; basic biology of IL17, in vitro and in vivo studies of IL17 deficiency, animal or human models of IL17 deficiency, and induced deficiency with anti-IL17 deficiency. Of 104 articles, 46 were included in this review.</p></div><div><h3>Results</h3><p>Deficiencies in the IL17 pathway can result in both bacterial and fungal infections and increased tumor growth. IL17 deficiency states are associated with susceptibility to infections from <em>Staphylococcus aureus, Mycobacterium tuberculosis</em> and <em>Candida albicans.</em> IL17 deficiency attenuates rheumatoid arthritis, atopic dermatitis, hapten-induced contact hypersensitivity and irritable bowel disease and is protective in lung cancer.</p></div><div><h3>Limitations</h3><p>Ultimately, clinical trials will determine the side effects of IL17 targeted therapeutics.</p></div><div><h3>Conclusion</h3><p>The implications of the information found in this review demonstrate potential effects to consider when using IL17 targeted therapeutics in the treatment of psoriasis.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 73-79"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.03.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72643009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Psoriasis and connective tissue diseases: What about Sjogren syndrome? 牛皮癣和结缔组织疾病:干燥综合征怎么办?

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2015.04.001

Zohra Aydi, Sana Toujani, Fatma Daoud, Besma Ben Dhaou, Lilia Baili, Fatma Boussema

引用次数: 1

A case report of heart failure after therapy with ustekinumab ustekinumab治疗后心力衰竭1例报告

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2015.03.003

Kourosh Beroukhim , Melissa Danesh , Catherine Nguyen , John Koo , Argentina Leon

引用次数: 6

Treatment of cutaneous leishmaniasis by topical 25% podophyllin solution (single, blinded, therapeutic, controlled study) 外用25%鬼紫素溶液治疗皮肤利什曼病(单、盲、治疗性对照研究)

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2014.10.001

Khalifa E. Sharquie , Adil A. Noaimi , Ahmed G. Al-Ghazzi

{"title":"Treatment of cutaneous leishmaniasis by topical 25% podophyllin solution (single, blinded, therapeutic, controlled study)","authors":"Khalifa E. Sharquie , Adil A. Noaimi , Ahmed G. Al-Ghazzi","doi":"10.1016/j.jdds.2014.10.001","DOIUrl":"10.1016/j.jdds.2014.10.001","url":null,"abstract":"<div><h3>Background</h3><p>There are many therapies that had been used to treat cutaneous leishmaniasis (CL).</p></div><div><h3>Objective</h3><p>To evaluate the effectiveness of topical 25% podophyllin solution in treatment of CL.</p></div><div><h3>Patients and methods</h3><p>Sixty-five patients with acute CL enrolled in this study, which was done in the Department of Dermatology, Baghdad Teaching Hospital, Baghdad, during January 2008–April 2009.The total number of lesions was 124 and duration of lesions ranged from 3 to 12(6.84±2.902)weeks. The size of lesions ranged from 0.5 to 3(1.75±1.81)cm. Diagnosis was confirmed by biopsy and smear. Lesions were divided into two groups with matching of type and size of lesions</p><p><em>Group A</em> treated with topical 25% podophyllin solution once weekly for number of sessions ranged from 3 to 6(4.51±0.85) sessions.</p><p><em>Group B</em> was left untreated as a control group. Follow up was every 2weeks for 8weeks.</p></div><div><h3>Results</h3><p>The total number of lesions was 120:79(65.84%) were ulcerated and 41(34.16%) were dry and 25(40.32%) patients had single lesion while 37(59.677%) patients had multiple lesions.</p><p><em>Group A:</em> 51(85%) lesions out of 60 lesions had cure with number of sessions ranging from 3 to 6(5.137±0.9385) sessions.</p><p><em>Group B:</em> no lesion was cured.</p></div><div><h3>Conclusions</h3><p>Topical 25% podophyllin is a new effective topical therapy for CL, with few side effects.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 108-113"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2014.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76753024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Madura foot: Report of a eumycetoma Moroccan case 马杜拉足:摩洛哥一例尘肺肿病例报告

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jssdds.2013.12.004

Naoufal Hjira , Adil Boudhas , Abderrahmane Al Bouzidi , Mohammed Boui

引用次数: 6

Recurrent non-healing perianal ulcer: A case of tuberculosis cutis orificialis 复发性不愈合肛周溃疡1例

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2014.08.003

Khalid Mohammed Al Attas, Mohammad Kamrul Ahsan, Hasan Yehia Hannani, Amr Mohammed Gamal, Srinivas Bhavanarushi

引用次数: 0

Failure of non-cultured melanocyte–keratinocyte transplantation in periungual vitiligo: A case report 非培养黑色素细胞-角化细胞移植治疗甲周白癜风失败1例

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2014.10.002

Norah Alsubait , Sanjeev Mulekar , Ahmed Al Issa

{"title":"Failure of non-cultured melanocyte–keratinocyte transplantation in periungual vitiligo: A case report","authors":"Norah Alsubait , Sanjeev Mulekar , Ahmed Al Issa","doi":"10.1016/j.jdds.2014.10.002","DOIUrl":"10.1016/j.jdds.2014.10.002","url":null,"abstract":"<div><h3>Background</h3><p>Vitiligo is a common pigmentary skin disorder, affecting 0.5–1% of world population. It is one of the psychologically devastating skin disorders, which have different medical and surgical modalities of treatment.</p></div><div><h3>Objective</h3><p>To report the failure of non-cultured melanocyte–keratinocyte transplantation in periungual vitiligo.</p></div><div><h3>Method</h3><p>The method used was introduced by Gauthier and Surleve-Bazeille, modified by Olsson and Juhlin, and recently by Mulekar. A shaved biopsy skin sample of approximately one-fifth the size of the recipient area was used. Skin sample is incubated; cells mechanically separated using trypsin-EDTA solution, and then centrifuged to prepare a suspension. The suspension is then applied to dermabraded depigmented skin area and collagen dressing was used to keep it in place.</p></div><div><h3>Results</h3><p>Treated lesions on the right hand of female with stable periungual vitiligo showed very poor repigmentation (less than 10%) with only very small new brown spots.</p></div><div><h3>Conclusion</h3><p>Acral vitiligo is one of the difficult-to-treat areas, and further studies are required to explain the variable outcomes of non-cultured melanocyte–keratinocyte transplantation treatment of clinically stable acral vitiligo patients.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 123-125"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2014.10.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74254260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Extensive anogenital lichen sclerosus with vaginal stenosis: A case report 广泛的肛门生殖器硬化地衣伴阴道狭窄1例

IF 0.4

Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jssdds.2013.11.002

Ahmed Samy El-agwany

引用次数: 1

Psychological disorders associated with rosacea: Analysis of unscripted comments 与酒渣鼻相关的心理障碍:非脚本评论分析

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Journal of Dermatology & Dermatologic Surgery-JDDS Pub Date : 2015-07-01 DOI: 10.1016/j.jdds.2015.04.003

Leah A. Cardwell , Michael E. Farhangian , Hossein Alinia , Sandy Kuo , Steve R. Feldman

{"title":"Psychological disorders associated with rosacea: Analysis of unscripted comments","authors":"Leah A. Cardwell , Michael E. Farhangian , Hossein Alinia , Sandy Kuo , Steve R. Feldman","doi":"10.1016/j.jdds.2015.04.003","DOIUrl":"10.1016/j.jdds.2015.04.003","url":null,"abstract":"<div><p><em>Background:</em> Conditions affecting the face are particularly prone to causing psychological comorbidity; patients may be reluctant to inform their physician about their psychological distress. Unscripted comments could provide novel insight regarding the psychological impact of rosacea. <em>Aim:</em> To assess psychologically distressing aspects of rosacea reported in an informal medical setting. <em>Methods:</em> Random sample of 10% of 27,051 posts analyzed, 446 comments addressed psychological effects of rosacea. Comments analyzed for symptoms of depression, anxiety, low confidence/self-esteem, and aspects of rosacea which cause distress, including symptoms, lifestyle change and difficulty with treatments. Brand names were changed to generic equivalent. <em>Results:</em> Symptoms of depression (<em>n</em>  =6) were mentioned, but no comments expounded on any suicide plan. Anxiousness (<em>n</em>  =5) were mentioned. Symptoms, or clinical manifestations (<em>n</em>  =20). Patients also voiced difficulty with treatments (<em>n</em>  <!-->15). <em>Limitations:</em> Online forums may provide patient perceptions that patients would not share with a doctor, but the sample may not be representative of all rosacea patients. <em>Conclusions:</em> Inquiring about psychological impact of rosacea might be helpful in identifying patients who would benefit from supportive psychological measures.</p></div>","PeriodicalId":43409,"journal":{"name":"Journal of Dermatology & Dermatologic Surgery-JDDS","volume":"19 2","pages":"Pages 99-103"},"PeriodicalIF":0.4,"publicationDate":"2015-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jdds.2015.04.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84529573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12