Polish Journal of Otolaryngology最新文献

{"title":"Vocal fold electromyography in patients with endoscopic features of unilateral laryngeal paralysis.","authors":"Paulina Krasnodębska, Beata Miaśkiewicz, Agata Szkiełkowska, Henryk Skarżyński","doi":"10.5604/01.3001.0053.8704","DOIUrl":"https://doi.org/10.5604/01.3001.0053.8704","url":null,"abstract":"<p><p>&lt;b&gt;&lt;br&gt;Introduction:&lt;/b&gt; Electromyography (EMG) of the larynx provides information on the electrophysiological condition of laryngeal muscles and innervation. Integration of information obtained from the EMG exams with the clinical parameters as obtained by other methods for laryngeal assessment (endoscopy, perceptual and acoustic analysis, voice self-assessment) provides a multidimensional picture of dysphonia, which is of particular importance in patients with vocal fold (VF) mobility disorders accompanied by glottic insufficiency.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Aim:&lt;/b&gt; The aim of this study was to evaluate laryngeal EMG records acquired in subjects with unilateral vocal fold immobilization with signs of atrophy and glottic insufficiency.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Material and methods:&lt;/b&gt; From the available material of 74 EMG records of patients referred for the exam due to unilateral laryngeal paralysis, records of 17 patients with endoscopic features suggestive of complete laryngeal muscle denervation were selected. The EMG study of thyroarytenoid muscles of mobile and immobile VFs was evaluated qualitatively and quantitatively at rest and during volitional activity involving free phonation of vowel /e/ [ε].&lt;/br&gt; &lt;b&gt;&lt;br&gt;Results:&lt;/b&gt; In all patients, the EMG records from mobile VFs were significantly different from those from immobile VFs. Despite endoscopic features of paralysis, no VF activity whatsoever was observed in as few as 2 patients so as to meet the neurophysiological definition of paralysis. In 88% of cases, electromyographic activity of the thyroarytenoid muscle was observed despite immobilization and atrophy of the vocal fold. In these patients, neurogenic type of record was observed with numerous high- -amplitude mobility units. On the basis of the results, quantitative features of EMG records indicative of paralysis and residual activity of the thyroarytenoid muscle were determined.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Conclusions:&lt;/b&gt; Qualitative and quantitative analysis of laryngeal EMG records provides detailed information on the condition of vocal fold muscles and innervation. EMG records of mobile vs immobile VFs differ significantly from each other. Endoscopic evaluation does not provide sufficient basis for the diagnosis of complete laryngeal muscle denervation.&lt;/br&gt.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"78 2","pages":"18-22"},"PeriodicalIF":0.6,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patogenesis of tinnitus in patients with post-COVID syndrome - preliminary report.","authors":"Paweł Rozbicki, Sandra Krzywdzińska, Michał Kaczmarczyk, Jacek Usowski, Arkadiusz Lubas, Dariusz Jurkiewicz","doi":"10.5604/01.3001.0053.8645","DOIUrl":"10.5604/01.3001.0053.8645","url":null,"abstract":"<p><p>&lt;b&gt;&lt;br&gt;Introduction:&lt;/b&gt; Similarly to hearing loss and dizziness, tinnitus is a frequently reported complication of COVID-19 and remains the subject of numerous scientific reports. However, the exact impact of SARS-CoV-2 on the pathophysiology of tinnitus observed in post-COVID syndrome remains unclear. One suspected cause behind the development of vestibulocochlear symptoms is the inflammation of neural tissue triggered by SARS-CoV-2 infection.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Aim:&lt;/b&gt; The aim of this study was to analyze the results of Brainstem Auditory Evoked Potentials (BAEP) in the context of tinnitus development among patients diagnosed with post-COVID syndrome.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Material and methods:&lt;/b&gt; This retrospective study involved the analysis of BAEP test results of patients admitted to the Audiology Clinic of the Military Institute of Medicine at the National Research Institute and diagnosed with the post-COVID syndrome. The study compared the average latency values of waves I, II, III, IV, V, and intervals I-III, III-V, I-V. The statistical analysis of the obtained data was performed.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Results:&lt;/b&gt; Out of 18 patients (9 female, 9 male) with an average age of 54.22 years (9.65) diagnosed with post-COVID syndrome, tinnitus was identified in 5 individuals (27.78%). A statistically significant increase in wave V latency (5.98 vs. 5.63 [ms]; P &lt; 0.05) and interval III-V (1.99 vs. 1.71 [ms]; P&lt;0.05) was observed between the groups of patients with and without tinnitus.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Discussion:&lt;/b&gt; Study results analyzing BAEP changes in patients with post-COVID syndrome in the context of tinnitus are insufficient in current literature. The only available report linking post-COVID syndrome with sensorineural hearing loss demonstrated a statistically significant increase in latency values of waves III, V, and an increase in intervals I-III, III-V.&lt;/br&gt; &lt;b&gt;&lt;br&gt;Conclusions:&lt;/b&gt; Tinnitus in patients suffering from post-COVID syndrome may be related to prolonged conduction of nerve impulses within the brainstem auditory pathway. Detailed pathophysiology of these changes requires further research.&lt;/br&gt.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 6","pages":"18-22"},"PeriodicalIF":0.6,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The analysis of etiology and treatment of chronic rhinosinusitis in our own material.","authors":"Natalia Ratajczyk-Socha,&nbsp;Jurek Olszewski","doi":"10.5604/01.3001.0016.2343","DOIUrl":"https://doi.org/10.5604/01.3001.0016.2343","url":null,"abstract":"<p><p>&lt;b&gt;Introduction and aim:&lt;/b&gt; The aim of the study was the analysis of etiology and treatment of chronic rhinosinusitis in our own material.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Material and methods:&lt;/b&gt; The study was performed on 520 women aged 18-87 and 789 men aged 19-85, diagnosed and treated for chronic rhinosinusitis between 2016 and 2020. The analysis was based on the medical records, taking into account: gender; age; type of symptoms; allergy tests; probable cause of inflammation; type of anatomical anomalies; assessment of the stage based on the Lund-Mackay score for CT scans; number of operations; pathology report; postoperative complications.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; The study showed that the hospitalized patients were most often aged 41-50, 51-60, and 31-40 for women and 51-60, 41-50, and 31-40 for men, respectively. The results of allergy tests in chronic rhinosinusitis patients showed that women were most often allergic to Pyralgin + Ketonal + paracetamol + ibuprofen in 4.50%, to penicillins in 1.07%, and to house dust mites in 0.92%, while in men positive reactions were found in 3.36% for Pyralgin + Ketonal + paracetamol + ibuprofen, 0.99% for house dust mites and 0.92% for cat and dog hair, respectively. Absence of anatomical anomalies was found in 20.75% of women and 26.36% of men, but most often they occurred in the form of deviated nasal septum and enlarged middle nasal concha. The pathology reports revealed the following: chronic rhinosinusitis, chronic polypoid rhinosinusitis, chronic cystic rhinosinusitis, and chronic allergic rhinosinusitis.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusions:&lt;/b&gt; The main symptoms in patients with chronic rhinosinusitis included: nasal congestion + rhinorrhea, nasal congestion + nasal discharge + olfactory impairment, and nasal congestion + nasal discharge + headache. The most common probable causes of chronic rhinosinusitis in the studied patients included: anatomical anomalies, allergies, and irritants including tobacco smoke. Depending on the assessment of the stage based on the Lund-Mackay score for CT scans, it appears that moderate to severe inflammation prevailed in the studied patients.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 4","pages":"14-22"},"PeriodicalIF":0.6,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health care system efficiency in otolaryngological surgeries during COVID-19 pandemic in years 2020-2021 compared to years 2018-2019: data from the Military Institute of Medicine in Warsaw.","authors":"Piotr Rot,&nbsp;Jakub Nicer,&nbsp;Łukasz Skrzypiec,&nbsp;Jakub Nowocień,&nbsp;Aldona Chloupek,&nbsp;Dariusz Jurkiewicz,&nbsp;Maria Sobol","doi":"10.5604/01.3001.0053.6709","DOIUrl":"10.5604/01.3001.0053.6709","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Coronavirus disease 19 (COVID-19) pandemic had a great impact on the health care system. This resulted not only from changes in the way medical facilities operated but also from the need to treat a huge number of patients. On the other hand, uninfected people feared visiting the doctor.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Aim:&lt;/b&gt; The aim of the study was to assess the impact of the COVID-19 pandemic on the diagnostics and treatment of patients with head and neck cancer.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Materials and methods:&lt;/b&gt; This retrospective study involved analysis of data of patients from a single hospital unit who underwent surgical procedures due to head and neck cancer during the COVID-19 pandemic in years 2020-2021 (pandemic group) compared to years 2018-2019 (pre-pandemic group).&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; Patients in the pandemic group (n = 123) were older and were more likely to have grade 3 cancer than patients in the pre-pandemic group (n = 116). Cancer stages were similar in both groups. During the pandemic, time from the first outpatient visit to surgery was longer (median 1.6 vs. 0.8 months), while time to radiotherapy was shorter (median 50.5 vs. 63 days) than in the pre-pandemic period.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusion:&lt;/b&gt; During the pandemic, patients had to wait slightly longer for surgery but not for radiotherapy when compared with the pre-pandemic period. Despite this, they did not have more advanced disease.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 4","pages":"48-52"},"PeriodicalIF":0.6,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41151916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An algorithmic approach to sinonasal evaluation preceding bone marrow transplantation.","authors":"Matin Ghazizadeh,&nbsp;Golfam Mehrparvar,&nbsp;Maryam Ghazizadeh","doi":"10.5604/01.3001.0053.4752","DOIUrl":"10.5604/01.3001.0053.4752","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; The authors conducted this study to review the available resources and prepare an algorithmic approach to pre-transplantation sinonasal evaluation.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Materials and methods:&lt;/b&gt; The sources of data were PubMed, Cochrane databases, and Google Scholar. We searched the available database for English-language studies using the keywords rhinosinusitis, transplantation, post -transplant sinusitis. Studies of all designs were included.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; Thirty-five relevant studies were retrieved from a total of 182 articles. The review of references guided us to 5more publications.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Discussion:&lt;/b&gt; We have proposed an algorithmic approach to sinonasal evaluation before transplantation which can provide a brief but comprehensive assessment of the patients. The evaluation begins with a thorough history and physical examination, including nasal endoscopy with careful attention to objective evidence of inflammation. CT scan should not be considered in all of the cases.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusion:&lt;/b&gt; We have suggested an algorithm to provide a comprehensive and cost-effective way for the evaluation of sinonasal diseases before planned immunosuppression in order to assist in reducing post-transplantation morbidity and mortality.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 4","pages":"7-13"},"PeriodicalIF":0.6,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41119905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The assesment of intraoperative use of mesna in canal wall-up cholesteatoma surgery - preliminary report.","authors":"Marta Pietraszek,&nbsp;Anna Bartochowska,&nbsp;Małgorzata Wierzbicka,&nbsp;Wojciech Gawęcki","doi":"10.5604/01.3001.0016.3415","DOIUrl":"https://doi.org/10.5604/01.3001.0016.3415","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Surgery is still the method of choice in chronic otitis media with cholesteatoma. Except for some specific clinical situations, classic canal wall up technique (CWU), remains a gold standard as a primary treatment in most departments. Unfortunately, the risk of recurrence in such an approach is estimated at 9 to even 70%. This fact prompts researchers to look for ways to reduce those unfavourable statistics. One of the recognized methods supporting the removal of cholesteatoma is the intraoperative use of mesna (sodium 2-mercaptoethanesulfonate). This synthetic sulphur compound disrupts disulfide bridges in polypeptide chains, thanks to which it facilitates matrix preparation.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Aim:&lt;/b&gt; To evaluate the effect of intraoperative use of mesna on the treatment outcomes in patients with chronic otitis media with cholesteatoma operated on by means of the canal wall up technique (CWU).&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Material and methods:&lt;/b&gt; 459 surgical reports of patients with middle ear cholesteatoma were analyzed. In total, 52 adult patients with no history of previous ear surgery operated on by means of the CWU technique by the same experienced otosurgeon with all follow-up data available were included in the study. Twenty-six were operated on with the use of mesna (mesna group) and 26 by means of the classic CWU technique (control / no-mesna group). There were 28 women and 24 men with a mean age of 41 years.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Main Outcome Measure(s):&lt;/b&gt; Postoperative hearing results and cholesteatoma recidivism rate.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; Overall recidivism rate was 21.15 %. It was higher in the no-mesna (26.9%) than in the mesna group (15.4%) - although the outcomes were better in the mesna group, the difference was not statistically significant (P = 0.49715). Hearing gain was better in the mesna than in the no-mesna group (10 dB vs 7 dB), but the difference was not statistically significant (P = 0.20089).&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusions:&lt;/b&gt; Our preliminary results show that mesna reduces recidivism rates in patients with cholesteatoma. Further study with the analysis of a larger group of patients is needed to prove it statistically.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 4","pages":"1-6"},"PeriodicalIF":0.6,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41177226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of mastoid portion of facial nerve course in temporal bone using computed tomography.","authors":"Paulina Szot,&nbsp;Iga Płachta,&nbsp;Emilia Nagórska,&nbsp;Eliza Brożek-Mądry","doi":"10.5604/01.3001.0016.3300","DOIUrl":"https://doi.org/10.5604/01.3001.0016.3300","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; The facial nerve (FN) follows a complex route in the temporal bone. Successful temporal bone surgery requires knowledge of its course which can be achieved using imaging methods such as computed tomography. This investigation aims to analyze the FN course in its mastoid portion and second genu and the frequency of its atypical course.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Material and methods:&lt;/b&gt; This is a retrospective study that enrolled 104 CT scans of temporal bones of patients followed up in the outpatient clinic of the Otorhinolaryngology Department of Dentistry Faculty of the Medical University of Warsaw between 2020 and 2022. FN courses were classified as straight, bulging, or letter \"S\"-like. Other parameters estimated: &lt;/br&gt; • position of the second genu according to the prominence of the lateral semicircular canal (classified as lateral, medial, or middle) and its distance from a line adjacent to the lateral semicircular canal was measured;&lt;/br&gt; • the distance between the short process of the incus and the outermost point of the second genu;&lt;/br&gt; • the course of the mastoid portion of FN and the location of SG in comparison to the tympanic portion of n. VII. The course was later classified as lateral, medial, or middle.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; Among the 104 assessed temporal bones, the course of the mastoid portion of FN was classified as bulging in 47 cases (45.2%). Straight and letter \"S\"-like courses were present in 41 (39.4%) and 16 (15.4%) cases, respectively. Deviation of the second genu according to the prominence of the lateral semicircular canal was medial in 86 cases (82.7%), and middle in 4 cases (3.8%). In the rest, second genu was paramedian to the prominence of the later circular canal. The mean distance between the short process of the incus and the outermost point of SG was 4.9 mm (0.73 mm). The mastoid portion was located laterally, medially, and in the middle of the tympanic portion plane in, respectively, 4.8%, 83.7%, and 11.5%. The second genu was located laterally, medially, and in the middle of the tympanic portion plane in 1.9%, 73.1%, and 25%, respectively. In conclusion, seven temporal bones (6.7%) of five patients presented with a lateral displacement of FN in relation to the established anatomical landmarks.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusions:&lt;/b&gt; Although the atypical course of FN, including the lateral displacement of the mastoid portion, is rare, screening for it is crucial before surgical exploration.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 4","pages":"39-47"},"PeriodicalIF":0.6,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41164398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Difficult glottis: Diagnostic dilemma in viewof the clinical presentation.","authors":"Hanna Klimza,&nbsp;Joanna Witkiewicz,&nbsp;Joanna Jackowska,&nbsp;Małgorzata Wierzbicka","doi":"10.5604/01.3001.0053.7263","DOIUrl":"10.5604/01.3001.0053.7263","url":null,"abstract":"<p><p>&lt;br&gt;&lt;b&gt;Introduction:&lt;/b&gt; The taxonomy of vocal fold lesions has been refined, and it serves as a common descriptive language for diagnosis, treatment algorithms, and reporting of outcomes. However, we observe rare cases when numerous pathologies overlap, resulting in an unclear and complicated clinical presentation of the glottis.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; The aim of this paper is to present cases of overlapping etiopathological factors which poses a challenge when making a diagnosis and referring a patient for adequate treatment.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Material and method:&lt;/b&gt; The study presents different photographs of the glottis, including some unique and unusual images in which overlapping pathologies were captured. The photographs are accompanied by case descriptions, comments, and pathological analyses.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Results:&lt;/b&gt; Four selected photographs showed a bunch of exophytic growth lesions with foci of whitish plaques, covered by yellowish crusts, with thinned, reddened vocal folds presenting foci of leukoplakia. The study discussed possible causes of vocal folds edema, diffuse erythema, presence of crusts or exudate, whitish debris/plaques or development of leukoplakia, non-neoplastic ulceration, as well as injected and reddened mucous membrane. Chronic infectious laryngitis, idiopathic ulcerative laryngitis, and drug-induced laryngitis were also mentioned. The study also raised the issues concerning diabetics and patients treated with inhaled corticosteroids, including candidiasis and primary aspergillosis of the larynx.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; To conclude, everyday clinical practice involves encountering cases of unclear onset and course, with complicated presentation of the glottis. Therefore, comprehensive history-taking and thorough investigation of systemic causes are of immense importance. Recommended management includes conducting the most meticulous differential diagnosis, implementing treatment for the most likely cause, and, whenever possible, refraining from biopsy in order to avoid permanent damage to vocal cords.&lt;/br&gt.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 4","pages":"53-57"},"PeriodicalIF":0.6,"publicationDate":"2023-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41104642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biologicals in the treatment of chronic rhinosinusitis with nasal polyps – position of the Polish Society of Otorhinolaryngologists –Head and Neck Surgeons and the Polish Society of Allergology experts","authors":"Dariusz Jurkiewicz, Maciej Kupczyk, Eliza Brożek-Mądry, Piotr Rapiejko","doi":"10.5604/01.3001.0053.5965","DOIUrl":"10.5604/01.3001.0053.5965","url":null,"abstract":"<p><p>Chronic rhinosinusitis with nasal polyps (CRSwNP) has a significant impact on the well-being and social functions of the \u0000patient. The generalized inflammatory process with the formation of nasal polyps and excess eosinophils in the mucosa of \u0000the paranasal sinuses is called type 2 inflammation, which is mediated by Th2 lymphocytes – cells of the immune system \u0000responsible for chronic inflammatory processes. Today, we also know the key pro-inflammatory mediators against which new \u0000drugs have been developed, the so-called biological drugs, are produced in cell lines. In this document, we present currently \u0000available biologicals approved for the treatment of patients with T2-related chronic rhinosinusitis.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 2","pages":"1-11"},"PeriodicalIF":0.6,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9738957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The management of sudden sensorineural hearing loss during COVID-19 pandemic.","authors":"Paweł Rozbicki,&nbsp;Jacek Usowski,&nbsp;Jacek Siewiera,&nbsp;Dariusz Jurkiewicz","doi":"10.5604/01.3001.0016.3301","DOIUrl":"https://doi.org/10.5604/01.3001.0016.3301","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; The COVID-19 pandemic constituted a significant challenge for healthcare systems. Epidemiological restrictions led to deferral of healthcare and influenced the variety of symptoms reported by patients suffering from Sudden Sensorineural Hearing Loss.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Aim:&lt;/b&gt; The aim of the study was to compare the duration of treatment implementation and symptoms reported by patients suffering from SSNHL before and during the COVID-19 pandemic.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Material and methods:&lt;/b&gt; Patients admitted to the Military Institute of Medicine - National Research Institute for SSNHL treatment were included in a survey conducted between 01.10.2021-31.12.2021. Questions on symptoms reported, chronic conditions, timeframe between first symptoms and implementation of pharmacotherapy, and hyperbaric oxygen therapy were included in the survey. The results were compared with data obtained by the Team between 01.2017-12.2019.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; 34 patients (19 females, 15 males) of the average age of 46.3 who participated in the survey indicated a significantly delayed implementation of pharmacotherapy and hyperbaric oxygen therapy in comparison to population from before the pandemic (12.08 vs. 5.41 [days]; 17.5 vs. 8.29 [days]). The survey also showed differences in the number of symptoms reported.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Discussion:&lt;/b&gt; The differences in time of implementation of SSNHL treatment could have been related to pandemic restrictions which contributed to longer queueing for health benefits and fear of contact with health service. Differences in symptomatology point towards SARS-CoV-2 as a pathogenetic factor of SSNHL.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusions:&lt;/b&gt; The COVID-19 pandemic significantly influenced the treatment of Sudden Sensorineural Hearing Loss. The study demonstrated a diverse symptomatology of SSNHL before and during the pandemic.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"77 3","pages":"7-11"},"PeriodicalIF":0.6,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41165363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}