Polish Journal of Otolaryngology最新文献

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Tonsillar origin of deep neck infection as a negative prognostic factor for developing complications. 深颈感染的扁桃体起源是发生并发症的负面预后因素。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-10-28 DOI: 10.5604/01.3001.0015.3431
P. Matoušek, L. Čábalová, Debora Formánková, L. Staníková, P. Čelakovský, J. Mejzlík, V. Chrobok, P. Komínek
{"title":"Tonsillar origin of deep neck infection as a negative prognostic factor for developing complications.","authors":"P. Matoušek, L. Čábalová, Debora Formánková, L. Staníková, P. Čelakovský, J. Mejzlík, V. Chrobok, P. Komínek","doi":"10.5604/01.3001.0015.3431","DOIUrl":"https://doi.org/10.5604/01.3001.0015.3431","url":null,"abstract":"Aim: The aim of this study was to compare the odontogenic and tonsillar origins of deep neck infection (DNI) as a negative prognostic factor for developing complications. Methods: This was a retrospective study of 544 patients with tonsillar and odontogenic origins of DNI treated between 2006 and 2015 at 6 ENT Departments and Departments of Oral and Maxillofacial Surgery. Complications from DNI (descending mediastinitis, sepsis, thrombosis of the internal jugular vein, pneumonia, and pleuritis) were evaluated in both groups and compared. Associated comorbidities (cardiovascular involvement, hepatopathy, diabetes mellitus respiratory involvement, gastroduodenal involvement) were reviewed. Results: Five hundred and forty-four patients were analyzed; 350/544 males (64.3%) and 19/544 females (35.7%). There were 505/544 cases (92.8%) with an odontogenic origin and 39/544 cases (7.2%) with a tonsillar origin of DNI. Complications occurred more frequently in the group with tonsillar origin of DNI (P < 0.001). There was no difference in diabetes mellitus between the two groups. Conclusions: Currently, the tonsillar origin of DNI occurs much less frequently; nevertheless, it carries a much higher risk of developing complications than cases with an odontogenic origin. We recommend that these potentially high-risk patients with a tonsillar origin of deep neck infections should be more closely monitored.","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"56 1","pages":"42-45"},"PeriodicalIF":0.6,"publicationDate":"2021-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85975056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in free flaps' reconstructions with and without coupling device for venous anastomosis. 静脉吻合术中有偶联装置与无偶联装置自由皮瓣重建的差异。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-09-30 DOI: 10.5604/01.3001.0015.3207
M. Rysz, Filip Kissin
{"title":"Differences in free flaps' reconstructions with and without coupling device for venous anastomosis.","authors":"M. Rysz, Filip Kissin","doi":"10.5604/01.3001.0015.3207","DOIUrl":"https://doi.org/10.5604/01.3001.0015.3207","url":null,"abstract":"Introduction: Introduction of the coupler devices for anastomoses of neck vessels changes planning and performance of the surgical procedures. The Rigid ring of the coupling devices keeps a vein open and less prone to occlusion. Therefore, this should improve the flap survival rate and surgery duration. Aim: The aim of the study was to point out the differences in surgery planning between couplers and sutures for venous microsurgical anastomoses. Methods: The medical records of 209 patients who underwent 212 microvascular free flap reconstructions from January 2011 till December 2017 were retrospectively analyzed; 103 received radial forearm free flap (RFFF); 43 - anterolateral thigh flap (ALTF); 51 - fibula free flap (FFF); 15 - iliac crest free flap (ICFF). In 189 cases, reconstruction was performed simultaneously with tumor resection and in 23 cases, reconstruction was secondary, after previous oncological treatment. Among 443 anastomoses, suturing was used for 212 arteries and 127 venous anastomoses, while coupling was used for 104 venous anastomoses. Results: The mean surgery duration for suturing was 452.82 min vs 358.88 min for coupling (P<0.05). Differences in flap survival and partial necrosis rates between coupling and suturing groups were not statistically significant (P>0.05). Donor vessel distribution in the neck was significantly different in both groups. Estimated costs of the surgical procedures performed with and without coupler devices were not equal. Conclusions: The use of couplers for venous anastomosis in free flap head and neck reconstructions impacts the surgery process by shortening surgery duration which leads to cost reduction..","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"22 1","pages":"6-12"},"PeriodicalIF":0.6,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83477722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laryngeal High-Speed Videoendoscopy with Laser Illumination: A Preliminary Report. 激光照明喉部高速视频内窥镜:初步报告。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-09-07 DOI: 10.5604/01.3001.0015.2575
Jakub Malinowski, Ewa Niebudek-Bogusz, Marcin Just, Joanna Morawska, Anna Racino, Joanna Hoffman, Magda Barańska, Magdalena Marianna Kowalczyk, Wioletta Pietruszewska
{"title":"Laryngeal High-Speed Videoendoscopy with Laser Illumination: A Preliminary Report.","authors":"Jakub Malinowski,&nbsp;Ewa Niebudek-Bogusz,&nbsp;Marcin Just,&nbsp;Joanna Morawska,&nbsp;Anna Racino,&nbsp;Joanna Hoffman,&nbsp;Magda Barańska,&nbsp;Magdalena Marianna Kowalczyk,&nbsp;Wioletta Pietruszewska","doi":"10.5604/01.3001.0015.2575","DOIUrl":"https://doi.org/10.5604/01.3001.0015.2575","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;br&gt;&lt;b&gt;Introduction:&lt;/b&gt; Advances in computer image analysis have enabled the use of new functional imaging methods in the diagnosis of laryngeal diseases. Particularly interesting techniques of dynamic laryngeal imaging involve High Speed Videoendoscopy (HSV). This still-developed technique allows to overcome the limitations of laryngovideostroboscopy (LVS) and a more detailed analysis of the glottal function based on the image of the actual vibrations of the vocal folds. It also enables the determination of objective coefficients parameterizing phonatory vibrations of the vocal folds.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Aim:&lt;/b&gt; The aim of this pilot study was to evaluate the use of a high-speed videoendoscopy set with laser illumination for the diagnosis of glottic pathology in ENT practice.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Material and methods:&lt;/b&gt; The study included 40 patients who underwent LVS followed by HSV. The modern HSV examination kit - Advanced Larynx Imager System (ALIS), used for the first time in a clinical setting in Poland, is characterized by significantly improved, compared to the previously used high-speed cameras, operational parameters - a light head, the possibility of continuous lighting operation without excessive heating of the head tip, registration of the image in full color scale. Thanks to such modernization, the safety and course of the examination do not differ from laryngoscopy conducted with commonly used recorders. The device owes some of these improvements to a laser illuminator which was used for the first time as the main light source in a high-speed camera. In the study, two cases were selected to present the results of HSV and the analysis of the generated kymograms - a woman with no glottic pathology and a man with a polyp of the right vocal fold. In the first case, the HSV examination compared with the LVS revealed a discrete glottis functional disorder in the form of a tendency to hyperphonation. The patient with an organic lesion had a clearly visible irregularity of vocal fold vibrations, which also allowed to trace mucosal wave disturbances related to its reflection from the pathological structure of the glottis and the formation of a return wave, both on the fold affected by the lesion and, to a lesser extent, contralaterally. The glottic dysfunctions observed in the studied patients were confirmed in the generated kymograms and the graphs of the glottal width waveform (GWW), as well as in the parameters calculated on their basis, assessing the frequency and amplitude of phonatory vibrations.&lt;/br&gt; &lt;br&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The use of high-speed videoendoscopy allows for a much more accurate assessment of the phonatory function of the glottis than in laryngovideostroboscopy. The presented HSV system allows for obtaining high quality kinematic images of the larynx, color fidelity, and contrast. The use of this technology in laryngological practice enab","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 6","pages":"1-10"},"PeriodicalIF":0.6,"publicationDate":"2021-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Acute sinusitis in daily clinical practice. 急性鼻窦炎在日常临床实践中。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-08-31 DOI: 10.5604/01.3001.0015.2378
Magdalena Arcimowicz
{"title":"Acute sinusitis in daily clinical practice.","authors":"Magdalena Arcimowicz","doi":"10.5604/01.3001.0015.2378","DOIUrl":"https://doi.org/10.5604/01.3001.0015.2378","url":null,"abstract":"<p><p>Understanding the appropriate use of diagnostics and treatment in acute rhinosinusitis is of immense importance given the high prevalence of this disease in the general population. The ability to differentiate between the principal phenotypes of acute sinusitis, namely acute viral infection (cold), acute post-viral sinusitis and acute bacterial sinusitis, determines the future management and is fundamental to providing rational therapeutic recommendations - especially as regards antibiotic treatment, which is very often overused in acute sinusitis even though bacterial phenotypes only account for 0.5-2% of all cases of the disease. The latest therapeutic recommendations contained in the EPOS2020 position paper introduce a system based on integrated care pathways (ICPs), which comprise pharmacy-supported self-care and e-health as the first level, followed by primary care as the second, with specialist care being reserved for patients who develop a more severe course of the disease, have suspected complications or suffer from recurrent acute sinusitis. Management of acute sinusitis is primarily based on symptomatic treatment modalities, with phytotherapeutic support, as well as on antiinflammatory treatment, while antibiotic therapy is used in very specific and limited indications. Complications are relatively rare in acute sinusitis and they are not considered to be associated with antibiotic intake. Considering the high prevalence of acute forms of sinusitis, their significant impact on quality of life and high direct and indirect costs of treatment, the right diagnosis and management, without unnecessary escalation of therapy, can substantially translate into a number of public health benefits.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 4","pages":"40-50"},"PeriodicalIF":0.6,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39442117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Early or late tracheotomy in patients after multiple organ trauma. 多器官创伤后早期或晚期气管切开术。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-07-06 DOI: 10.5604/01.3001.0015.0083
Łukasz Skrzypiec, Piotr Rot, Maciej Fus, Agnieszka Witkowska, Marcin Możański, Dariusz Jurkiewicz
{"title":"Early or late tracheotomy in patients after multiple organ trauma.","authors":"Łukasz Skrzypiec,&nbsp;Piotr Rot,&nbsp;Maciej Fus,&nbsp;Agnieszka Witkowska,&nbsp;Marcin Możański,&nbsp;Dariusz Jurkiewicz","doi":"10.5604/01.3001.0015.0083","DOIUrl":"https://doi.org/10.5604/01.3001.0015.0083","url":null,"abstract":"<p><p>The analysis of the study group of 124 patients revealed a statistically significant shortening of mechanical ventilation requirement period in patients in whom tracheotomy had been performed before hospitalization day 10 (G1). The average length of mechanical ventilation was shorter by 20.3 days in G1 as compared to G2. On average, the duration of ICU stay was shorter by 39.4 days in G1 as compared to G2. Total hospitalization time was also significantly shorter in this group of patients (G1). The overall length of hospital stay for patients in whom tracheotomy had been performed prior to hospitalization day 10 was on average 43.1 days shorter as compared to patients in whom the procedure had been performed at a later date. Tab. I. provides the comparison of the results obtained in both study groups. Statistically significant differences (p &lt; 0.05) were demonstrated between G1 and G2 regarding the length of the mechanical ventilation, the length of ICU stay, and length of hospitalization. null null No statistically significant differences were observed in mortality rates between the study groups (Fig. 1.) (P = 0.256). The mortality rate in early tracheotomy group (G1) was lower and amounted to 2%. In patients in whom tracheotomy was performed on day 10 or later (G2), the mortality rate was slightly higher and amounted to 9%. In some patients, initiation of treatment was required due to pneumonia developing as a complication in mechanically ventilated patients and referred to as ventilator-associated pneumonia. This complication developed in 6 patients in G1 and 26 patients in G2. The study assessed the relationship between the occurrence of this complication and the timing of tracheotomy. Pneumonia was significantly more frequent in patients in whom tracheotomy had been performed on hospitalization day 10 or later (P = 0.011). null null The comparison of results is presented in Tab. II.&lt;/br&gt; &lt;/br&gt;Another analyzed aspect of the study consisted in the results obtained by the patients in the baseline evaluation of the level of consciousness as assessed using the Glasgow Coma Scale (GCS). Data were checked for potential correlation between the GCS scores and the timing of the tracheotomy and the lengths of mechanical ventilation, ICU stay, and hospitalization. Correlation between GCS scores and the duration of stay within the ICU was demonstrated with a statistically significant correlation coefficient (Spearman's rank coefficient in the range of -0.4 to -0.2). &lt;/br&gt; &lt;/br&gt;ICU stay and total hospitalization lengths were shorter in patients with higher baseline GCS scores compared to patients with lower baseline GCS scores. The results are illustrated graphically (Fig. 2., 3.).</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 6","pages":"23-27"},"PeriodicalIF":0.6,"publicationDate":"2021-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A randomized, double-blind, placebo- -controlled study to investigate the use of bacteriophages in patients with chronic rhinosinusitis with nasal polyps. 一项随机、双盲、安慰剂对照的研究,旨在研究噬菌体在慢性鼻窦炎合并鼻息肉患者中的应用。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-06-30 DOI: 10.5604/01.3001.0015.0084
Konstantin Grigorievich Dobretsov, Oxana Kolenchukova, Alexander Sipkin, Luisa Maria Bellussi, Giorgio Ciprandi, Desiderio Passali
{"title":"A randomized, double-blind, placebo- -controlled study to investigate the use of bacteriophages in patients with chronic rhinosinusitis with nasal polyps.","authors":"Konstantin Grigorievich Dobretsov,&nbsp;Oxana Kolenchukova,&nbsp;Alexander Sipkin,&nbsp;Luisa Maria Bellussi,&nbsp;Giorgio Ciprandi,&nbsp;Desiderio Passali","doi":"10.5604/01.3001.0015.0084","DOIUrl":"https://doi.org/10.5604/01.3001.0015.0084","url":null,"abstract":"<p><p>Background A randomized, double-blind placebo-controlled study investigated the use of bacteriophages in the treatment of chronic rhinosinusitis with nasal polyps. Materials and Methods 40 adult patients with сhronic rhinosinusitis with nasal polyps were examined. All patients underwent functional endoscopic sinus surgery. After the surgery, 20 patients got the intranasal gel with a bacteriophages mixture (Otofag, Micromir, Russia) twice a day for ten weeks, and 20 patients got a placebo. Results On the 10th day, IL-1β secretion diminished (63 mg/ml versus 440 mg/ml in control). There was a decrease in the total number of microorganisms and Enterobacteriaceae (5.7 x 106 CFU/ml versus 1.2 x 109 CFU/ml in control), and the absence of Streptococci (versus 2.1 x 109 CFU/ml in control) on the 30th day of the treatment in the group with the bacteriophages. On the 10th day, a decrease in the activity of secretory IL-1β and IL-8 strongly and very strongly correlated with a total number of microorganisms (r = 0.7; r = 0.9 respectively), as well as secretory IL-8 with Enterobacteriaceae (r = 0.72) and Staphylococci (r = 0.65) in the active group treated with the bacteriophages. On the 30th day, the decrease in serum IL-1β significantly correlated with the total number of microorganisms (r = 0.80) and enterobacteria (r = 0.90) in the active group. Conclusions The administration of bacteriophages restored the balance of microorganisms in the nasal cavity and decreased the inflammatory response in chronic rhinosinusitis with nasal polyps. These changes, such as an inflammation dampening, could theoretically reduce the recurrent growth of polyp tissue in the future.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 6","pages":"33-37"},"PeriodicalIF":0.6,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Piezoelectric bone conduction hearing implant Osia® - audiological and quality of life benefits. 压电骨传导助听器Osia®-听力学和生活质量的好处。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-06-24 DOI: 10.5604/01.3001.0014.9342
Joanna Marszał, Renata Gibasiewicz, Magdalena Błaszczyk, Maria Gawłowska, Wojciech Gawęcki
{"title":"Piezoelectric bone conduction hearing implant Osia® - audiological and quality of life benefits.","authors":"Joanna Marszał,&nbsp;Renata Gibasiewicz,&nbsp;Magdalena Błaszczyk,&nbsp;Maria Gawłowska,&nbsp;Wojciech Gawęcki","doi":"10.5604/01.3001.0014.9342","DOIUrl":"https://doi.org/10.5604/01.3001.0014.9342","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Nowadays, there are many options to treat hearing-impaired patients: tympanoplastic surgery, hearing aids and a wide range of implantable devices.&lt;/br&gt;&lt;/br&gt; &lt;b&gt;Aim:&lt;/b&gt; The aim of this study is to present the mid-term audiological and quality of life benefits after the implantation of Osia®, an active piezoelectric bone conduction hearing implant. &lt;/br&gt;&lt;/br&gt; &lt;b&gt;Material and methods:&lt;/b&gt; The state of the tissues in the implanted area, as well as audiological and quality of life results were analyzed at six, nine and twelve months after implantation in a group of four adult patients with bilateral mixed hearing loss (1 after bilateral canal-wall-down mastoidectomy, 2 with chronic simple otitis media and after myringoplasty in the opposite ear, 1 with bilateral otosclerosis and after stapedotomy in the opposite ear). &lt;/br&gt;&lt;/br&gt; &lt;b&gt;Results:&lt;/b&gt; No postoperative complications were found in any of the cases. One year after surgery the mean audiological gain in FF PTA4 (pure tone average for 0.5, 1, 2, and 4 kHz) was 52.2 ± 3.5 dB in comparison to the unaided situation, the mean speech understanding with Osia® in quiet was 90 ± 8.2% for 50 dB SPL, 98.8 ± 2.5% for 65 dB SPL and 100 ± 0% for 80 dB SPL, and the mean speech understanding with Osia® in noise was 37.5% ± 23.6 for 50 dB SPL, 93.8 ± 4.8% for 65 dB SPL and 98.8 ± 2.5% for 80 dB SPL. There was also an evident improvement in the quality of hearing as well as in the quality of life, measured by APHAB (Abbreviated Profile of Hearing Aid Benefit) and SSQ (Speech, Spatial and Qualities of Hearing Scale). &lt;/br&gt;&lt;/br&gt; &lt;b&gt;Conclusions:&lt;/b&gt; The Osia® is an effective treatment option for patients with bilateral mixed hearing loss. The mid-term audiological and quality of life results are excellent, but further observations including bigger groups of patients and a longer follow- -up are required.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 6","pages":"11-22"},"PeriodicalIF":0.6,"publicationDate":"2021-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
OK-432 treatment of pediatric patients with recurrent thyroglossal duct cyst after surgery. OK-432治疗小儿甲状腺舌管囊肿术后复发。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-06-16 DOI: 10.5604/01.3001.0014.9073
Nobuo Ohta, Shigeru Fukase, Miho Nakazumi, Teruyuki Sato, Takahiro Suzuki
{"title":"OK-432 treatment of pediatric patients with recurrent thyroglossal duct cyst after surgery.","authors":"Nobuo Ohta,&nbsp;Shigeru Fukase,&nbsp;Miho Nakazumi,&nbsp;Teruyuki Sato,&nbsp;Takahiro Suzuki","doi":"10.5604/01.3001.0014.9073","DOIUrl":"https://doi.org/10.5604/01.3001.0014.9073","url":null,"abstract":"<p><p>&lt;b&gt;Introduction:&lt;/b&gt; Recurrent thyroglossal duct cyst after surgery is not a rare condition and first-line treatment has not been established yet.&lt;br/&gt;&lt;br/&gt; &lt;b&gt;Aim:&lt;/b&gt; Evaluation of outcomes and complications of OK-432 treatment in patients with recurrent thyroglossal duct cyst after surgery. &lt;br/&gt;&lt;br/&gt; &lt;b&gt;Material and methods:&lt;/b&gt; This study is designed as a case series with planned data collection at Tohoku Medical and Pharmaceutical University and Fukase Clinic. Five patients with recurrent thyroglossal duct cyst after surgery received this therapy between January 2014 and February 2020 on an outpatient basis, without hospitalization. OK-432 solution was injected into the lesion using an 18- or 27-gauge needle, depending on the location and size of the lesion, as well as on possible complications.&lt;br/&gt; &lt;br/&gt; &lt;b&gt;Results:&lt;/b&gt; Lesions showed marked reduction or total shrinkage in all patients, with no local scarring or deformity at the injection site. Side effects manifested as local pain at the site of injection and fever (37.5-38.5°C) observed in three patients, but the symptoms resolved within a few days.&lt;br/&gt; &lt;br/&gt; &lt;b&gt;Conclusions:&lt;/b&gt; Since OK-432 therapy is simple, easy, safe and effective, it can be used as an alternative to surgery in the treatment of recurrent thyroglossal duct cyst after surgery.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 6","pages":"28-32"},"PeriodicalIF":0.6,"publicationDate":"2021-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The impact of radiotherapy on the quality of life in patients with early-stage clinical head and neck cancer. 放疗对早期临床头颈癌患者生活质量的影响。
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-05-12 DOI: 10.5604/01.3001.0014.8759
Jakub Milecki, Małgorzata Żmijewska-Tomczak, Krzysztof Osmola, Małgorzata Wierzbicka
{"title":"The impact of radiotherapy on the quality of life in patients with early-stage clinical head and neck cancer.","authors":"Jakub Milecki,&nbsp;Małgorzata Żmijewska-Tomczak,&nbsp;Krzysztof Osmola,&nbsp;Małgorzata Wierzbicka","doi":"10.5604/01.3001.0014.8759","DOIUrl":"https://doi.org/10.5604/01.3001.0014.8759","url":null,"abstract":"<p><p>Radiotherapy (RT) for patients with head and neck squamous cell carcinoma (HNSCC) affects vital functions related to the irradiation volume of the head and neck region and, in addition, has a negative impact on social functioning, thereby significantly impairing patients' quality of life (QoL). The aim of this study was to assess changes in the quality of life in patients with head and neck cancer treated with curative RT at 12 months after completion of RT. The aim of this study was to assess the differences between the baseline QoL of patients with early clinical stage HNSCC and at 12 months after curative/radical RT. The prospective clinical study included 92 patients in good general condition (ECOG 0-1 - Eastern Cooperative Oncology Group performance status), without regional or distant metastases, diagnosed with pathomorphologically confirmed early-stage head and neck squamous cell carcinoma treated with definitive RT. All patients participating in the study signed an informed consent form. QoL was assessed using the standard EORTC QLQ-C30 and QLQH&amp;N35 questionnaires. In addition, information on clinical aspects and data relating to socio-demographic factors were obtained from each patient. Statistical analysis was performed using a statistical package (SPSS 17.0). T-test was used for dependent and independent samples. A general linear model was used for repeated measures. Patients' QoL deteriorated significantly after definitive RT. Worse QoL Core-30 scores in patients 12 months after the end of RT, compared with baseline QoL, before the start of RT, were observed in domains such as physical performance, fulfillment of life roles, cognitive functioning, loss of appetite, fatigue and constipation. For the QLQ-H&amp;N35 questionnaires, patients 12 months after the end of RT reported problems in relation to aspects of life such as senses, mouth opening, dry mouth, thick saliva, pain, and weight loss. RT, even in early clinical stage head and neck cancer, has a negative impact on QoL, despite modern treatment techniques.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":"75 5","pages":"1-8"},"PeriodicalIF":0.6,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39439653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Does neuromonitoring affect voice quality in patients subjected to a complete thyroidectomy ? 神经监测是否会影响甲状腺全切除术患者的语音质量?
IF 0.6
Polish Journal of Otolaryngology Pub Date : 2021-05-12 DOI: 10.5604/01.3001.0014.8779
Piotr Bryk, Stanislaw Głuszek
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