Sensors and Actuators B: Chemical最新文献

{"title":"Ion-Selective Optical Sensors with Internal Reference: on the Quest for Prolonged Functionality and Calibration-Free Measurements","authors":"Nikolai Yu. Tiuftiakov, Andrey V. Kalinichev, Ivan P. Gryazev, Maria A. Peshkova","doi":"10.1016/j.snb.2025.138231","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138231","url":null,"abstract":"As with most chemical sensors, the proliferation of optodes in analytical routine is hampered by the need for periodic sensor calibration. This fundamental limitation arises from a number of chemical and technological factors (e.g., instability of the illumination source, changes in the composition of the sensor phase, etc.), leading to deviation of the optodes signal in parallel measurements and over time. The development of new approaches for calibration-free determination of analytes with optodes remains a pertinent challenge in the field of chemical sensors. The presented study is aimed at the development and validation of ion-selective optical sensor arrays that do not require calibration. These arrays incorporate an internal optical signal reference composed of polymeric optodes with suppressed exchange capacity. The applicability of such optodes as optical signal standards is demonstrated in a broad range of pH and background electrolyte concentrations: from pH 5 to 9 in solutions of cations and lipophilic anions with concentrations reaching 0.1<!-- --> <!-- -->M. This experimental observation is supported by theoretical analyses performed by numerical simulation. The study identifies the effect of coextraction and ion exchange on the range of the optical signal stability. Furthermore, it is shown both theoretically and experimentally that by modulating the acidity of the lipophilic indicator in the standard optode, the operational range of the internal reference can be adjusted to the desired pH or electrolyte concentrations. In addition, the validation results demonstrate the feasibility of determining Na⁺ concentration in the sample using internal standards with fair accuracy.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"76 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A near-infrared fluorescent probe for the detection of vicinal-dithiol-containing proteins and its application in vivo","authors":"Guangwei Wang, Fang-Fang Guo, Jiaojiao Wu, Liang-Liang Gao, Xinrong Tian, Jianjian Zhang, Yuan Guo","doi":"10.1016/j.snb.2025.138235","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138235","url":null,"abstract":"Vicinal-dithiol-containing proteins (VDPs) play a significant role in maintaining cellular redox homeostasis and serve as important biomarkers for diagnosing redox-related diseases, such as obesity and cancer. However, the currently reported fluorescent probes are restricted in biological applications due to their short emission wavelengths and insufficient sensitivity. To address this limitation, we developed a novel near-infrared fluorescent probe (<strong>M1</strong>) for sensitive tracking of VDPs by utilizing coumarin-benzopyrylium moiety as the fluorophore and two methoxy-substituted maleimide groups matching double active cysteine residues of VDPs as the recognition site. <strong>M1</strong> exhibits negligible fluorescence in aqueous media but emits strong red fluorescence upon specific binding to VDPs. The probe shows high sensitivity for detecting reduced bovine serum albumin (rBSA) within the concentration range of 0-7.5<!-- --> <!-- -->μM, with a detection limit as low as 0.070<!-- --> <!-- -->μM. Furthermore, <strong>M1</strong> has been successfully applied not only to super-resolution fluorescence imaging of VDPs in A549 cells, but also to confocal fluorescence imaging of VDPs in zebrafish.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"11 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An integrated metal-organic frameworks and membrane fusion platform for the separation and detection of exosome miRNA in thyroid cancer diagnosis","authors":"Jing Chen ,&nbsp;Qianying Zhou ,&nbsp;Huiying Xie ,&nbsp;Simin Liu ,&nbsp;Jing Peng ,&nbsp;Ting Huang ,&nbsp;Yanyan Chen ,&nbsp;Jin-Xiang Chen ,&nbsp;Jun Chen ,&nbsp;Zong Dai ,&nbsp;Minmin Li","doi":"10.1016/j.snb.2025.138219","DOIUrl":"10.1016/j.snb.2025.138219","url":null,"abstract":"<div><div>Traditional diagnosis of thyroid cancer involves invasive procedures, making it crucial to find convenient and rapid methods for early detection of thyroid cancer. Exosomal miRNA has emerged as a potential and effective biomarker for thyroid cancer diagnosis. However, simple, rapid, and sensitive analysis of exosomal miRNA remains challenging. In this study, we present an integrated platform for the rapid separation of exosomes using metal-organic frameworks (MOF) materials, followed by membrane-fusion-based DNAzyme signal amplification for the highly sensitive detection of miR-31 within extracellular vesicles (EVs), aiming to achieve early diagnosis of thyroid cancer. For the proposed method, MOF not only serves as a medium for separating EVs but also releases Zn^2 + upon acid-induced cleavage, which further acts as a cofactor for DNAzyme, reducing the cost and simplifying the process. Furthermore, the combination of membrane fusion-based DNAzyme circuits for miRNA analysis in EVs shows high sensitivity with a detection limit of 1.05 × 10 ³ particles/mL. The method can also effectively and accurately distinguish the expression of miR-31 in the plasma EVs of normal and thyroid cancer patients. This strategy has high accuracy and practicality and is expected to play an important role in disease diagnosis and drug research.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"443 ","pages":"Article 138219"},"PeriodicalIF":8.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterostructured multimetallic CoFe2O4@CeCuOx nanozyme from dual-MOF for efficient detection and degradation of hydroquinone","authors":"Fang-Yue Ning ,&nbsp;Zhi-Fang Wang ,&nbsp;Ying Li,&nbsp;Yan-Feng Huang","doi":"10.1016/j.snb.2025.138232","DOIUrl":"10.1016/j.snb.2025.138232","url":null,"abstract":"<div><div>The phenolic contaminants can severely affect human health and aquatic environment because of their high ecotoxicity and carcinogenic risk. Accordingly, the design and construction of MOF-based nanozymes with superior catalytic performance and high stability is indispensable for sensing and degradation of hydroquinone (HQ) in water. In this work, a novel dual-MOF composite precursor was fabricated by deposition a layer of FeCo-PBAs on CeCu-MOF nanosheets. Then the dual-MOF precursor comprising multiple metallic species Fe, Co, Ce, and Cu within the heterostructure was converted into quasi-dual-MOF (a multimetallic mixed-valence CoFe₂O₄@CeCuO_x composite) by low-temperature pyrolysis. The resulting CoFe₂O₄@CeCuO_x not just inherited exceptional properties of dual-MOF, but also greatly enhanced structural stability and robustness. More importantly, it showed improved peroxidase-like activity by synergistic effects and demonstrated outstanding performance for HQ detection with a wide linear range of 5–300 µM，a low detection limit of 0.458 µM. Further utilizing the peroxidase-like activity, CoFe₂O₄@CeCuO_x was used in activating H₂O₂ for HQ degradation with 98.3 % removal within 75 min. This work offers a novel avenue for the feasible design of highly active nanozymes for sensing and pollutant removal.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"443 ","pages":"Article 138232"},"PeriodicalIF":8.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A self-accelerated responsive fluorescent sensor for rapid and specific cancer biomarker EpCAM detection and cancer imaging in vivo","authors":"Sirui Bai, Jinfeng Yang, Long He, Abdukerem Abduwahap, Xiangya Dou, Xuezhou Yang, Jiayun Liu, Huiyun Xu, Dong-En Wang","doi":"10.1016/j.snb.2025.138230","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138230","url":null,"abstract":"The detection and in-situ fluorescence imaging of cancer biomarkers are crucial for early cancer diagnosis, progression and treatment informing as well as prognosis evaluation. Epithelial cell adhesion molecule (EpCAM) is a protein-based cancer biomarker that has been affirmed as an attractive target for epithelioid cancer diagnosis and therapy. Current fluorescence sensors for EpCAM are limited by either being “always on” or sensing and imaging only in living cells, leading to high background interference or restricted practicability. In this study, a simple yet effective <strong>APN</strong> sensor based on aptamer-conjoined polydiacetylene nanoliposomes was developed for near-infrared (NIR) fluorescence turn-on sensing of EpCAM. Multiple electrostatic and noncovalent interactions among EpCAM, the aptamer and cationic polydiacetylene (PDA) nanoliposomes in the system synergistically produced a self-accelerated effect that enabled detection of EpCAM within few minutes with high sensitivity and selectivity. Our <strong>APN</strong> sensor could also realize the quantification and in-situ mapping of EpCAM in targeted cancer cells. Bioimaging studies in tumor-bearing mice modes further demonstrated the capability of <strong>APN</strong> sensor as an excellent imaging agent for sustained EpCAM-targeted cancer imaging <em>in vivo</em>. Additionally, <strong>APN</strong> sensor was further employed to delineate the cancer lesions in pathological sections from patients with breast cancer, showing favorable differentiating ability. Thus, our strategy not only establishes an appealing alternative for EpCAM sensing and targeted cancer imaging but also provides a universal sensing platform applicable to design sensors for other disease biomarkers.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"26 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deformable U-shaped microelectrodes made of carbon-PDMS for blood coagulation test","authors":"Wei Guan ,&nbsp;Fei Ma ,&nbsp;Yuan Luo ,&nbsp;Chengwu Han ,&nbsp;Fei Su ,&nbsp;Xiaoxing Xing","doi":"10.1016/j.snb.2025.138236","DOIUrl":"10.1016/j.snb.2025.138236","url":null,"abstract":"<div><div>Blood coagulation test is heavily required for a broad range of diseases. Microfluidic devices with much smaller footprints and sample consumption have emerged as promising tools for blood clotting assay compared with the commercialized instruments. However, the existing microdevices also pose challenges in terms of the dependency on the relatively costly labeling process and optical setup, as well as the complex fabrication process. In this paper, we demonstrate a deformable 3D U-shaped microelectrode made of conducting carbon-PDMS composite, which suspends in a microchannel for measuring blood clotting based on viscosity change. The microelectrode together with the device is fabricated by replica-molding process. Thus, it enables label-free electrical measurements via a mechanically deformed electrode implemented through low-cost and concise fabrication. The device is capable of measuring glycerol solutions, as modeled viscous fluids, with varied viscosities from 3 cP to 30 cP and infusion flow rates from 0.5 ml/min to 1 ml/min. We also demonstrate the device capability in differentiating the normal blood and the blood pre-treated with high and low concentrations of antiplatelet drug. Meanwhile, we further verify that the device output reflects a blood clotting tendency aligned with that indicated by the tests using clinical approach.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"443 ","pages":"Article 138236"},"PeriodicalIF":8.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implanted fiber-optic sensor for analyzing catalytic reactions and kinetics in Au/TiO2 systems","authors":"Duo Zhao ,&nbsp;Shiyu Jiang ,&nbsp;Junao Zhang ,&nbsp;Fengguo Zhu ,&nbsp;Yue Wang ,&nbsp;Ying Guo ,&nbsp;Siyu Qian","doi":"10.1016/j.snb.2025.138238","DOIUrl":"10.1016/j.snb.2025.138238","url":null,"abstract":"<div><div>In heterogeneous photocatalytic reactions, understanding the catalytic processes and its kinetics is crucial for catalyst design and performance evaluation. However, real-time monitoring the interface reaction such as pollutant degradation remains a challenge. In this study, the implantable optical fiber sensors with real-time catalytic monitoring capability were created by modifying the sensing surface with Au/TiO₂ heterojunction photocatalysts. As pollutants adsorb and degrade on the catalytic interface, surface refractive index changes occur. The evanescent field on the sensing surface covers the photocatalytic layer, enabling in situ and real-time monitoring of surface refractive index changes for catalytic reaction analysis. The flexible fiber-optic Surface Plasmon Resonance (SPR) sensors can be directly immersed in a pollutant solution Rhodamine 6 G (R6G) to monitor its degradation rate and kinetic processes. It reveals that the optimal size of Au nanoparticles (AuNPs) can facilitate efficient electron transfer at heterojunction catalysts. The time-resolved resonance wavelength shift further elucidates the degradation kinetics of photocatalysts with varying Au/TiO₂ composition. The fiber-optic sensor demonstrated comparable accuracy to conventional UV-Vis spectrophotometry in assessing TiO₂ photocatalytic degradation (84.13 % vs. 81.25 % efficiency, respectively), with a relative deviation less than 5 %. However, unlike the discrete data collected by traditional UV-Vis methods, the miniaturized and implantable fiber-optic SPR sensor can collect data every 0.25 s. It demonstrates real-time monitoring capability and enables more accurate evaluation of dynamic reaction processes. This in situ sensing strategy provides new insights into photocatalytic mechanisms and shows great potential for guiding catalyst design and optimization.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"443 ","pages":"Article 138238"},"PeriodicalIF":8.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and morphology-dependent CO2 gas sensing properties of Ca & Al codoped ZnO nanostructures","authors":"Yijun Yang ,&nbsp;JinBeom Kwon ,&nbsp;Dong Geon Jung ,&nbsp;Daewoong Jung","doi":"10.1016/j.snb.2025.138217","DOIUrl":"10.1016/j.snb.2025.138217","url":null,"abstract":"<div><div>Monitoring CO₂ emissions is critical due to their impact on climate change, necessitating the development of efficient gas sensors with high sensitivity and selectivity at moderate operating temperatures. This study investigated the gas-sensing performance of ZnO nanomaterials, particularly undoped ZnO and Ca,Al codoped ZnO, for CO₂ detection. Gas sensing measurements were conducted in a chamber with a fixed total flow rate of 1000 sccm, adjusting the temperature and CO₂ gas concentration between 1000 and 5000 ppm. Three types of ZnO nanomaterials, including nanowires (NWs), nanorods, and nanoparticles, were synthesized via a sol–gel method and evaluated for their gas-sensing capabilities. Among these, the NWs exhibited the highest response to CO₂. The Ca,Al codoped ZnO NWs demonstrated superior gas sensitivity, particularly at high CO₂ concentrations and at lower levels. The limit of detection for CO₂ was 6.65 ppm. Furthermore, the codoped ZnO NWs exhibited significant responses to various gases, with the highest response recorded for CO₂ (9.56 at 5000 ppm). This performance highlights the strong potential of the Ca,Al codoped ZnO NWs as effective gas sensors for CO₂ detection at moderate temperatures.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"443 ","pages":"Article 138217"},"PeriodicalIF":8.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic carbon dots nanozyme coupled in-situ growth strategy: Colorimetric/ratiometric fluorescent/photothermal multi-model detection of Microcystin-LR","authors":"Dan Chang,&nbsp;Yanan Yan,&nbsp;Jianyang Feng,&nbsp;Jianan Pei,&nbsp;Xintong Yang,&nbsp;Yang Liu,&nbsp;Lihong Shi,&nbsp;Shaomin Shuang,&nbsp;Chuan Dong","doi":"10.1016/j.snb.2025.138224","DOIUrl":"10.1016/j.snb.2025.138224","url":null,"abstract":"<div><div>Enzyme linked immunosorbent assay (ELISA) has become the gold standard assay format in multiple fields. Here, we develop a nano-catalyst-triggered cascade platform based on magnetic carbon dots nanozyme (MCDs) for colorimetric/ratiometric fluorescent/photothermal multi-model detection of Microcystin-LR (MC-LR). The multifunctional tracer (MCDs@PB) is first constructed by a simple in-suit shell-growing strategy. The synergy of MCDs and PB endows MCDs@PB with robust fluorescence emission, remarkable photothermal signal, favorable magnetic response, ultrahigh peroxidase mimicking activity along with superb antibody coupling efficiency. Notably, the Michaelis constant (K_m) and maximum reaction velocity (V_max) values of MCDs@PB are 0.56 mM and 11.12 × 10⁻⁸ M s⁻¹ for 3,3′,5,5′-tetramethylbenzidine (TMB), and 0.012 mM and 3.55 × 10⁻⁸ M s⁻¹ for hydrogen peroxide (H₂O₂), indicating that MCDs@PB have good affinity for both substrates. Leveraging this foundation, a triple-mode ELISA platform is designed. This platform consists of three parts: (1) catalytic amplification system triggered by TMB and H₂O₂, (2) ratiometric fluorescent analysis constructed by introducing rhodamine B into MCDs@PB-mediated ELISA system, and (3) photothermal assay achieved by the near-infrared laser-driven photothermal properties of oxidized TMB. The calculated limits of detection for MC-LR are 0.09 ng/mL in catalytic colorimetric mode, 0.12 ng/mL in ratiometric fluorescent mode, and 0.17 ng/mL in photothermal mode. The application feasibility of MCDs@PB-mediated ELISA is further verified in food and environmental samples with satisfactory recoveries. This work not only provides a new inspiration for the rational design of CDs-triggered signal tracers, but also exhibits their great potential in multimodal immunoassays.</div></div>","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"443 ","pages":"Article 138224"},"PeriodicalIF":8.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"G-Quadruplex/Hemin Self-Assembly Powered Homogeneous Electrochemical/Visual Sensor for Efficient and Reliable Detection of Ochratoxin A","authors":"Chunyuan Tang, Bingzheng Yuan, Libo Li, Lijun Luo, Tianyan You","doi":"10.1016/j.snb.2025.138233","DOIUrl":"https://doi.org/10.1016/j.snb.2025.138233","url":null,"abstract":"Electrochemical (EC) aptasensors stand out in ochratoxin A (OTA) detection due to their rapid analysis capabilities. However, existing EC aptasensors rely on layer-by-layer assembly techniques for immobilization. Thus, developing a simple technique that can efficiently and accurately detect OTA remains a significant challenge. Herein, an homogeneous EC/visual sensor is developed to achieve an efficient and reliable detection of OTA. First, gold nanoparticles grown on mesoporous polydopamine nanoparticles (AuNPs@mPDA) serve as nanocontainers for hemin encapsulation. OTA aptamers and SH-complementary DNA (SH-cDNA) act as a “biogate” to encapsulate hemin. The presence of OTA can trigger the opening of the biogate, releasing hemin, which then self-assembles into G-quadruplex/hemin DNAzyme (GQH). GQH acts as the electron transfer mediator, generating an EC signal. Meanwhile, GQH catalyzes colorimetric substrates, and the resulting visual response can be rapidly assessed for OTA contamination using a portable colorimeter. Overall, this homogeneous strategy and dual-signal mode effectively circumvent the errors induced by environmental factors and the tedious electrode preparation, thereby significantly enhancing the efficiency and reliability of detection. The proposed homogeneous sensor can sensitively electrochemically detect OTA in the range from 1<!-- --> <!-- -->pg/mL to 500<!-- --> <!-- -->ng/mL via the EC method and visually within the range from 100<!-- --> <!-- -->pg/mL to 500<!-- --> <!-- -->ng/mL. Furthermore, this sensor has exhibited satisfactory performance in the detection of OTA in complex food matrices, highlighting its potential in food safety monitoring.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":"46 1","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}