Sensors and Actuators B: Chemical最新文献

Anchor carbon dots inside NH2-MIL-88B via ship-in-a-bottle strategy for dual signal enhancement in colorimetric-fluorescent sensors 通过 "瓶中船 "策略在 NH2-MIL-88B 内锚定碳点，实现比色-荧光传感器的双信号增强

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-02 DOI: 10.1016/j.snb.2024.136877

Yuhao Lu, Xiuxiu Dong, Guanya Ji, Xuejing Wang, Tao Wang, Chengshun Tang, Oluwafunmilola Ola, Hongwei Duan, Qian Liu, Qijian Niu

{"title":"Anchor carbon dots inside NH2-MIL-88B via ship-in-a-bottle strategy for dual signal enhancement in colorimetric-fluorescent sensors","authors":"Yuhao Lu, Xiuxiu Dong, Guanya Ji, Xuejing Wang, Tao Wang, Chengshun Tang, Oluwafunmilola Ola, Hongwei Duan, Qian Liu, Qijian Niu","doi":"10.1016/j.snb.2024.136877","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136877","url":null,"abstract":"The increase in oxytetracycline (OTC) pollution has become a significant risk to ecological stability and human health because of excessive use. Therefore, developing a precise and reliable sensor for trace OTC detection is critical. In this work, a dual-mode sensor of colorimetric-fluorescent (CL-FL) with dual signal-on was developed for OTC detection. Firstly, a novel carbon dots encapsulating in cavities of MOFs composite (CDs@NH2-MIL-88B) was constructed by the ship-in-a-bottle approach, which enhanced peroxidase-like activity and fluorescent intensity. Further, combining with surface molecularly imprinted polymer (MIP), the dual-mode sensor was constructed to develop selectivity (CDs@NH2-MIL-88B@rMIP). Finally, the dual signal enhancement mechanism of the sensor comes from the interaction between OTC and identifying binding site involving strong hydrogen bonding and metal complexation from imprinted cavity and CDs@NH2-MIL-88B, respectively. The prepared sensor has a linear detection range of 1.00 × 10-9 - 1.00 × 10-5 M with the limit of detection (LOD) of 1.47 × 10-10 M for the CL mode and a detection range of 1.00 × 10-11 -1.00 × 10-7 M with the LOD of 1.84 × 10-12 M for the FL mode. Meanwhile, the sensor shows high sensitivity, accuracy and reliability in OTC detection. Overall, this work provides a promising CL-FL dual-mode sensing systems with signal-on in the detection of antibiotics and other hazardous pollutants.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic microactuator embedded electrochemical sensing platform towards on-demand sensor cleaning 实现按需清洗传感器的磁性微执行器嵌入式电化学传感平台

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-02 DOI: 10.1016/j.snb.2024.136715

Angel Enriquez, Jae Young Park, Dong Hoon Lee, Carl Russell, Urja Raipancholia, Abigail Ahrens, Jacqueline C. Linnes, Steven T. Wereley, Hyowon Lee

{"title":"Magnetic microactuator embedded electrochemical sensing platform towards on-demand sensor cleaning","authors":"Angel Enriquez, Jae Young Park, Dong Hoon Lee, Carl Russell, Urja Raipancholia, Abigail Ahrens, Jacqueline C. Linnes, Steven T. Wereley, Hyowon Lee","doi":"10.1016/j.snb.2024.136715","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136715","url":null,"abstract":"Reliable, time-resolved detection of biochemical markers is critical for providing actionable healthcare data. Biosensors can track various clinically relevant biomarkers to inform clinicians to make data-driven decisions. However, the notorious effects of complex fluids limit the lifetime of biosensors by fouling the active sensing sites, hindering their long-term functionality. Biomaterials with passive antifouling capabilities have been developed to minimize the effects of biofouling. However, these attempts can only delay the unavoidable outcome of fouling accumulation, which still limits long-term device functionality. Here, we present a novel class of biosensor capable of self-clearing their sensing surface that can avoid and actively remove biofoulants from the electrode surfaces. The active anti-biofouling modality consists of an electrochemical sensing platform embedded with magnetic microactuators previously proven to disrupt protein attachment and blood clot formation. In this study, we characterize the static and dynamic mechanical responses of the torsional thin-film magnetic microactuators. We confirm its protein-clearing capabilities using fluorescent bovine serum albumin. To quantify the advantages of magnetic actuation using electrochemical techniques, we conducted cyclic voltammetry and electrochemical impedance spectroscopy experiments. We believe this work presents a pivotal step towards enabling a truly longitudinal and continuous monitoring of multiple analytes in complex in vivo environment for a truly personalized medicine.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous monitoring of humidity and temperature by polarization volume gratings utilizing responsive cholesteric liquid crystals 利用响应性胆固醇液晶的偏振体积光栅同时监测湿度和温度

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-02 DOI: 10.1016/j.snb.2024.136879

Zhao-Yi Chen, Hao Yang, Shi-Long Li, Sen-Sen Li, Lu-Jian Chen

{"title":"Simultaneous monitoring of humidity and temperature by polarization volume gratings utilizing responsive cholesteric liquid crystals","authors":"Zhao-Yi Chen, Hao Yang, Shi-Long Li, Sen-Sen Li, Lu-Jian Chen","doi":"10.1016/j.snb.2024.136879","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136879","url":null,"abstract":"Optical sensing devices are utilized for noncontact operation in harsh environments due to their advantage of local separation between the measurement and detector systems. Cholesteric liquid crystals (CLCs) with vivid structural colors are integrated into optical sensors, attracting significant interest for naked-eye detection. To enable vision-based, real-time remote monitoring, we propose a cost-effective method to convert the stimuli-responsive reflection change of CLCs into recordable diffraction patterns using polarization volume gratings (PVGs). This enables real-time remote readout of environmental parameters. PVGs are constructed through holographic polarization interference and photoalignment technologies. The diffraction efficiency of PVGs varies with relative humidity (RH). To improve sensing accuracy and extend the monitoring range of RH, we employ two methods: an orthogonal grating structure and dual-wavelength detection optical path. In addition, we demonstrate the simultaneous measurement of humidity and temperature by cascading independently responding PVGs. We believe that this work will provide a broader perspective and expand the application of light dimensions in LC-based optical sensing.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual, fast and highly sensitive detection of zearalenone by two-color optical sensor based on label-free split aptazyme. 利用基于无标记拆分普酶的双色光学传感器，直观、快速、高灵敏地检测玉米赤霉烯酮。

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-02 DOI: 10.1016/j.snb.2024.136880

Tongtong Lai, Qinghong Sun, Zhimeng Lv, Linhui Xie, Shiwen Niu, Jingyan Zhang, Jiancai Tang, Shengmao Li, Yingping Luo

{"title":"Visual, fast and highly sensitive detection of zearalenone by two-color optical sensor based on label-free split aptazyme.","authors":"Tongtong Lai, Qinghong Sun, Zhimeng Lv, Linhui Xie, Shiwen Niu, Jingyan Zhang, Jiancai Tang, Shengmao Li, Yingping Luo","doi":"10.1016/j.snb.2024.136880","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136880","url":null,"abstract":"Concerning significant risks of zearalenone (ZEN) to human health and safety, a two-color optical sensor, termed as split aptazyme, was developed in this work. The constructed split aptazyme employed ZEN-binding split aptamer as highly target-recognized element and split G-quadruplex DNAzyme as efficient signal reporter. In the absence of ZEN, the two fragments of split aptazyme remained separate and the solution showed colorless. But in the presence of trace ZEN, these two segments would immediately assemble to form a complex that could perform oxidation of 2,2′-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) to colored ABTS•+ (dark green). More importantly, the solution color would change into yellowish-brown upon further increasing the concentration of ZEN, owing to a new reaction happening between excess ZEN and ABTS•+. This approach showed high selectivity towards ZEN over other tested toxins with a low measurable detection limit value of 6 nM. Notably, the split aptazyme was successfully applied for the quantitative detection of ZEN in real samples (millet, oat, coix seed, and bitter almond) and enabled naked-eye detection of ZEN at concentrations as low as 1 μM. Given that split aptazyme-based assay for ZEN determination was easy-to-use, label-free, equipment-free and rapid with high speciﬁcity and sensitivity, this developed sensing strategy would be readily applicable for on-site visual detection for other toxins via replacing the corresponding aptamer sequences.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graphene-based chemiresistive hydrogen sensor for room temperature operation 用于室温操作的石墨烯基化学电阻式氢传感器

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-02 DOI: 10.1016/j.snb.2024.136889

Cao Tang, Wei Jin, Xue Xiao, Xin Qi, Yanqing Ma, Lei Ma

引用次数: 0

A competitive cathodic photoelectrochemical sensor based on a signal amplification of CdIn2S4 photoanode for trenbolone detection 基于 CdIn2S4 光阳极信号放大的竞争性阴极光电化学传感器，用于检测群勃龙

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-01 DOI: 10.1016/j.snb.2024.136883

Jinkun Yuan, Xin Chen, Hongmin Ma, Zhongfeng Gao, Xiang Ren, Rui Xu, Dan Wu, Qin Wei

引用次数: 0

Toehold and Hairpin Assembly-Mediated Tripedal DNA Walker for Circulating Tumor DNA Detection in Human Blood 用于检测人体血液中循环肿瘤 DNA 的趾持式和发夹组装式三足 DNA Walker

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-11-01 DOI: 10.1016/j.snb.2024.136887

Wei Li, Jiayue Li, Shuaijing Wang, Manman Duan, Shang Sun, Wanling Cui, Zhenguang Wang

{"title":"Toehold and Hairpin Assembly-Mediated Tripedal DNA Walker for Circulating Tumor DNA Detection in Human Blood","authors":"Wei Li, Jiayue Li, Shuaijing Wang, Manman Duan, Shang Sun, Wanling Cui, Zhenguang Wang","doi":"10.1016/j.snb.2024.136887","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136887","url":null,"abstract":"Circulating tumor DNA (ctDNA) levels in the peripheral blood are correlated with tumor burden and malignant progression. Sensitive and accurate detection of ctDNA in human blood remains to be explored. This study introduces a novel approach that employs toehold-assisted ctDNA capture and hairpin assembly-mediated tripedal DNA walker, facilitating the sensitive detection of a broad range of ctDNAs. Specifically, the design includes a capture probe featuring an overhanging toehold domain for the identification of ctDNA, alongside three hairpin structures that incorporate blocked DNAzymes for the DNA walking mechanism. The capture probe identifies ctDNA through a toehold-mediated strand displacement reaction, which subsequently initiates the assembly of the three hairpin structures, resulting in the formation of a tripedal DNA walker. This tripedal walker is capable of initiating a walking process that generates detectable fluorescent signals for the quantification of ctDNA. The toehold-assisted ctDNA capture method demonstrates excellent accuracy and specificity for identical strands with a single-base mismatch, while the tripedal walker exhibits enhanced efficiency compared to bipedal and unipedal walkers. Furthermore, two stages of signal amplification were achieved, allowing for the sensitive detection of ctDNA with a detection limit of 0.3 fM in buffer solutions and 0.8 fM in serum samples. The quantitative analysis of ctDNA in human blood was effectively performed, demonstrating the method’s ability to distinguish between blood samples from healthy individuals and those from patients with tumor. Therefore, this method represents a significant advancement in ctDNA detection for clinical noninvasive liquid biopsies and holds considerable promise for tumor diagnosis.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142562308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-mode visual imaging of latent fingerprints based on organic fluorescent probe with enhanced TICT emission 基于增强 TICT 发射的有机荧光探针的潜伏指纹双模式视觉成像技术

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-10-31 DOI: 10.1016/j.snb.2024.136874

Zheng-Hong Pu, Jiao He, Xiang Liu, Jian Wang, Qing-Hong Bai, Cheng-Hui Wang, Xin Xiao

{"title":"Dual-mode visual imaging of latent fingerprints based on organic fluorescent probe with enhanced TICT emission","authors":"Zheng-Hong Pu, Jiao He, Xiang Liu, Jian Wang, Qing-Hong Bai, Cheng-Hui Wang, Xin Xiao","doi":"10.1016/j.snb.2024.136874","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136874","url":null,"abstract":"Fluorescence-based imaging has emerged as a promising technique for high-resolution visualization of latent fingerprints (LFPs), but detecting LFPs by fluorescent probes remains challenging at present. Herein, a water-soluble fluorescent dye (DEPN) with red emission and twisted intramolecular charge transfer (TICT) properties was synthesized, which function as a dual-mode in-situ imaging probe for LFPs. The desired solid composite fluorescent fingerprint powder DEPN@MMT can be obtained by milling with montmorillonite (MMT) to realize the imaging of LFPs with 1-3 levels of details, which has the advantages of simple preparation, low doping ratio, good photostability, and is not limited by the substrate. Comparison with the actual fingerprint details extracted by fingerprint reader revealed a good match between the both, indicating that the fingerprint powder has high application value. The permanent preservation of LFPs with different curvatures was also realized by making rubbings. In addition, DEPN was able to image LFPs in aqueous solution with a concentration of 50 μM over a wide pH range, and it took only 20 s to obtain high-quality images that met the NFIQ2 detection standard. This dual-mode imaging probe of LFPs is highly practical, offering adaptable detection patterns for a range of complicated situations. It provides a valuable method for rapid and convenient visualization of LFPs, as well as their subsequent preservation and analysis.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous dual-colour labelling of mitochondria and lysosomes: an indolium-based approach 线粒体和溶酶体的同步双色标记：基于吲哚鎓的方法

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-10-31 DOI: 10.1016/j.snb.2024.136862

Carlos Benitez-Martin, Francisco Najera, Ezequiel Perez-Inestrosa

引用次数: 0

Tuning the Peroxidase-Mimic Activity of CuX-Trithiocyanuric Acid Complexes for Colorimetric Detection of Gastric Cancer-Associated D-Amino Acids 调节 CuX-Trithiocyanuric Acid 复合物的过氧化物酶模拟活性以比色检测胃癌相关 D-氨基酸

IF 8.4 1区化学

Sensors and Actuators B: Chemical Pub Date : 2024-10-31 DOI: 10.1016/j.snb.2024.136871

Xiaoying Gao, Jiarui Zhu, Jiahui Zhao, Lei Zhao, Ying Sun, Jiazhen Lin, Mengli Hu, Yunjia Liu, Shenghong Yang, Jian Liu

{"title":"Tuning the Peroxidase-Mimic Activity of CuX-Trithiocyanuric Acid Complexes for Colorimetric Detection of Gastric Cancer-Associated D-Amino Acids","authors":"Xiaoying Gao, Jiarui Zhu, Jiahui Zhao, Lei Zhao, Ying Sun, Jiazhen Lin, Mengli Hu, Yunjia Liu, Shenghong Yang, Jian Liu","doi":"10.1016/j.snb.2024.136871","DOIUrl":"https://doi.org/10.1016/j.snb.2024.136871","url":null,"abstract":"A cascade colorimetric detection of salivary D-amino acids (DAAs) holds promise for the preliminary screening diagnosis of gastric cancer. Pursuing metal-organic complexes with high peroxidase-mimic (POD-mimic) activity is crucial to enhance diagnosis efficiency. In this work, we developed a straightforward strategy in a “one-pot” process to modulate the POD-mimic activity of CuX-trithiocyanuric acid (CuX-TTCA) complexes. By adjusting the molar ratios of CuX (Cl, Br, and I) and TTCA during synthesis to modify the coordination configuration of Cu(I) in CuX-TTCA, we easily tuned their POD-mimic activities. Among them, CuCl-TTCA-2 with a feeding molar ratio of 2:1 for CuCl:TTCA exhibited remarkable POD-mimic activity attributed to its exposed catalytic active sites and efficient mass transfer ability during catalysis. Long-lived 1O2 was identified as the primary reactive oxygen intermediate. A highly sensitive and selective cascade colorimetric detection platform was developed for two typical DAAs associated with gastric cancer, namely D-proline and D-alanine, achieving limit of detection values of 1.1 and 0.8 μM, respectively. As a proof-of-concept application, our cascade detection platform demonstrated excellent specificity in distinguishing saliva samples between gastric cancer patients and healthy individuals. The outstanding selectivity and reliable outcomes from DAAs assay make our detection platform highly promising for preliminary screening diagnosis of gastric cancer and patient self-detection applications. Our straightforward strategy for tuning POD-mimic activity provides an in-depth understanding on structure-activity relationship in nanozymes, offering valuable opportunities to advance enzyme-mimic optimization for other potential applications.","PeriodicalId":425,"journal":{"name":"Sensors and Actuators B: Chemical","volume":null,"pages":null},"PeriodicalIF":8.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0