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A rapid and non-immersed method of viscosity measurement with small-volume samples based on longitudinal guided waves in capillary 基于毛细管纵向导波的小体积样品粘度快速非浸没测量法
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-09-17 DOI: 10.1016/j.sbsr.2024.100692
Shaohong Qu , Songli Hu , Ting Li , Chaomin Wu , Yuexiu Chen , Linqian Zhao , Lihang Zhu , Jianjun Wu , Zhifeng Tang , Peifang Dong , Fengjiang Zhang
{"title":"A rapid and non-immersed method of viscosity measurement with small-volume samples based on longitudinal guided waves in capillary","authors":"Shaohong Qu ,&nbsp;Songli Hu ,&nbsp;Ting Li ,&nbsp;Chaomin Wu ,&nbsp;Yuexiu Chen ,&nbsp;Linqian Zhao ,&nbsp;Lihang Zhu ,&nbsp;Jianjun Wu ,&nbsp;Zhifeng Tang ,&nbsp;Peifang Dong ,&nbsp;Fengjiang Zhang","doi":"10.1016/j.sbsr.2024.100692","DOIUrl":"10.1016/j.sbsr.2024.100692","url":null,"abstract":"<div><div>Viscosity measurement is crucial in medical diagnostics, pharmaceuticals, and analytical chemistry, where samples are frequently in small volumes and measurements are supposed to be conducted in a short time with convenient approaches. In this study, we propose a viscosity measurement approach based on longitudinal guided waves with a dominant in-plane displacement. The viscosity is determined using the attenuation of longitudinal guided waves in a liquid-filled capillary. The use of guided waves accelerates the measurement while the application of a capillary reduces the sample volume. Additionally, the approach is nondestructive and repeatable since the liquid sample is injected into the capillary instead of immersing the probe into the liquid; the sample is located in a relatively closed tube, reducing the interferences of outside factors. In our propomsed method, the sample volume is only 176.6 μL and the measurement time of one sample is only 5.6 ms. The effectiveness and practicability of the proposed approach is confirmed by measuring silicon oils with viscosities from 9.01 mPa·s to 532 mPa·s and a limit of detection (LOD) of 0.97 mPa·s. The minimum error is about 5 % at 442 mPa·s and the maximum error is about 18 % at 9.01 mPa·s Besides, the approach was employed for detection of viscosity in artificial tear samples, which indicated that satisfactory applicability was achieved. This work not only demonstrates the judicious design of a rapid and non-immersed method for viscosity measurement, but also a promising scheme for point-of-care analysis of tear viscosity, thus offering great potential for at-home diagnosis and personalized healthcare of various ocular diseases.</div></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"46 ","pages":"Article 100692"},"PeriodicalIF":5.4,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosensing in the optical switch configuration on strong plasmonic gratings enabling differential referenced detection 在强等离子光栅的光学开关配置中进行生物传感,实现差分参考检测
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100681
Emilie Laffont , Arnaud Valour , Nicolas Crespo-Monteiro , Pierre Berini , Yves Jourlin
{"title":"Biosensing in the optical switch configuration on strong plasmonic gratings enabling differential referenced detection","authors":"Emilie Laffont ,&nbsp;Arnaud Valour ,&nbsp;Nicolas Crespo-Monteiro ,&nbsp;Pierre Berini ,&nbsp;Yves Jourlin","doi":"10.1016/j.sbsr.2024.100681","DOIUrl":"10.1016/j.sbsr.2024.100681","url":null,"abstract":"<div><p>A deep gold-coated sinusoidal grating is proposed as a transducer for label-free real-time biosensing, operating in a new configuration based on the optical switch effect, which produces complementary optical outputs enabling differential and referenced detection. Biosensing experiments are reported for the first time on this platform, using immunoassays involving biospecific pairs consisting of bovine serum albumin and its antibody, and human serum albumin and its antibody. Direct and sandwich immunoassays are demonstrated along with negative controls. A limit of detection of 6 pg/mm<sup>2</sup> was obtained. A theoretical model correlating the variation in the differential referenced output optical signal with adlayer growth is presented and supports the experimental results. The proposed detection device operating in the optical switch configuration makes a promising case for point-of-care detection applications because the differential detection of two diffracted orders enables common noise suppression and robust interrogation.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100681"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000631/pdfft?md5=82c8610a8f58931ded96d3a1afb0d26f&pid=1-s2.0-S2214180424000631-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142041129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and characterization of ss-DNA/RGO/MoS2 modified carbon paste electrode for highly sensitive detection of capecitabine 用于高灵敏度检测卡培他滨的ss-DNA/RGO/MoS2修饰碳浆电极的开发与表征
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100675
Masoumeh Mohammadi , Amir Abbas Rafati , Ahmad Bagheri
{"title":"Development and characterization of ss-DNA/RGO/MoS2 modified carbon paste electrode for highly sensitive detection of capecitabine","authors":"Masoumeh Mohammadi ,&nbsp;Amir Abbas Rafati ,&nbsp;Ahmad Bagheri","doi":"10.1016/j.sbsr.2024.100675","DOIUrl":"10.1016/j.sbsr.2024.100675","url":null,"abstract":"<div><p>Capecitabine (CAP) is a chemotherapeutic agent used in cancer treatment, necessitating the development of sensitive and selective detection methods for its analysis in clinical samples. The present research utilized a simplified procedure for developing a novel electrochemical sensor based on a carbon paste electrode (CPE) modified with single-stranded DNA (ss-DNA), reduced graphene oxide (RGO), and molybdenum disulfide (MoS2). Unmodified (bare CPE) and modified (ss-DNA/RGO/MoS<sub>2</sub>/CPE) electrodes were characterized by scanning electron microscopy (SEM), EDX analysis, and cyclic voltammetry (CV). Characterization data confirm the good conductivity and electrocatalytic nature with more electrochemically active sites in ss-DNA/RGO/MoS<sub>2</sub>/CPE compared to bare CPE in the determination of CAP in real samples. Two linear ranges were obtained for CAP concentration within the ranges of 0.01–10.00 μM and 10.00–60.00 μM, with a detection limit of 0.0108 μM and a limit of quantification of 0.036 μM. The lower linear concentration range of 0.01–10.00 μM showed a sensitivity of 276.85 AM<sup>−1</sup> cm<sup>−2</sup>, while the range of 10–60 μM had a sensitivity of 5.88 AM<sup>−1</sup> cm<sup>−2</sup>. The performance of the modified electrode was tested in human serum samples, yielding satisfactory recovery results. The selectivity and practical ability of ss-DNA/RGO/MoS<sub>2</sub>/CPE to determine CAP in the presence of different interfering species were investigated, demonstrating the sensor's selective, reliable, and accurate response.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100675"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000576/pdfft?md5=b2828545dadebaf9dd658e8b24369e33&pid=1-s2.0-S2214180424000576-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design of hexagonal shaped spectroscopy based biosensor for the detection of tuberculosis 设计基于六角形光谱的结核病检测生物传感器
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100682
Rakib Hossen , Md. Selim Hossain , Sadia Afrin Mim , Md. Al-Amin , Sabbir Ahmed , Md. Ashrafuzzaman , Md. Ashiq Salahin , Shuvo Sen
{"title":"Design of hexagonal shaped spectroscopy based biosensor for the detection of tuberculosis","authors":"Rakib Hossen ,&nbsp;Md. Selim Hossain ,&nbsp;Sadia Afrin Mim ,&nbsp;Md. Al-Amin ,&nbsp;Sabbir Ahmed ,&nbsp;Md. Ashrafuzzaman ,&nbsp;Md. Ashiq Salahin ,&nbsp;Shuvo Sen","doi":"10.1016/j.sbsr.2024.100682","DOIUrl":"10.1016/j.sbsr.2024.100682","url":null,"abstract":"<div><p>A proposal has been made to identify tuberculosis cells using a novel compact sensor based on photonic crystal fiber: PCF in accordance with hexagonal spectroscopy. This proposed structure, which consists of a closely packed hexagonal air hole in the cladding region and a hollow-core area, possesses a very low loss of 6.30 × 10<sup>−8</sup> dB/m and an exceptionally high sensitivity of up to 91.75 % (tuberculosis cell for 1.345). Numerous optical parameters have been identified and assessed, comprised of the numerical aperture, the V-parameter, or normalized frequency (V<sub>eff</sub>), and the effective area (A<sub>eff</sub>). The operational wavelength range is defined as 0.80–3.0 THz. The numerical investigation of the properties of the proposed TB sensors is performed within the environment of COMSOL Multiphysics (Version 5.3) using FV-FEM stands for the full vector finite element method. PCF sensors composed of hexagonal lattice in a circular form with ZEONEX as the backdrop material is intended to boost the sensitivity response in comparison to the earlier works. Additionally, the sensor that is being displayed achieves a single modality throughout its whole operational wavelength range. This proposed sensor may play a significant role in identifying tuberculosis thanks to its superior sensitivity response and extremely minimal confinement loss. So, it is clearly seen that this sensor could be used to bio-medical sectors with process of terahertz (THz) wave pulse.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100682"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000643/pdfft?md5=7c54a42c5e807d84b2c1af5ebcafa53e&pid=1-s2.0-S2214180424000643-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A pioneering electrochemical sensor for the simultaneous determination of nitrofurantoin and furazolidone residues in food and municipal wastewater samples 用于同时测定食品和城市污水样品中硝基呋喃妥因和呋喃唑酮残留量的开创性电化学传感器
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100678
Wondimeneh Dubale Adane, Bhagwan Singh Chandravanshi, Merid Tessema
{"title":"A pioneering electrochemical sensor for the simultaneous determination of nitrofurantoin and furazolidone residues in food and municipal wastewater samples","authors":"Wondimeneh Dubale Adane,&nbsp;Bhagwan Singh Chandravanshi,&nbsp;Merid Tessema","doi":"10.1016/j.sbsr.2024.100678","DOIUrl":"10.1016/j.sbsr.2024.100678","url":null,"abstract":"<div><p>In this study, a pioneering electrochemical sensor was developed for simultaneously determining nitrofurantoin (NFT) and furazolidone (FZD) residues in food and municipal wastewater samples. The sensor was prepared by integrating gold‑silver-alloy nanocoral clusters (Au-Ag-ANCCs) with zinc oxide nanoparticles (ZnO-NPs), carbon paste electrode (CPE) and polyethylene oxide (PEO) nanocomposites. The surface morphology and elemental compositions of Au-Ag-ANCCs/ZnO-NPs-CPE/PEO were characterized by FT-IR, XRD, SEM, EDX, EIS, and CV. The sensor showed exceptional performance over a wide linear range, from 1.0 pM to 250 μM for NFT and 0.9 nM to 360 μM for FZD. The detection and quantification limits were found to be 0.26 pM and 0.88 pM for NFT and 0.023 pM and 0.076 pM for FZD, respectively. In addition, the sensor exhibited excellent repeatability, reproducibility, selectivity, and long-lasting stability. When applied to the detection of AZM and ENF residues in poultry, fish, honey, dairy products and municipal wastewater, it exhibited excellent recoveries of 96.3–102.8% and relative standard deviations between 1.87% and 1.53%. In general, the developed sensor represents a significant advance in the fight against antibiotic residue pollution.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100678"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000606/pdfft?md5=5244175717dacaab194f51d448284fad&pid=1-s2.0-S2214180424000606-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid, low-cost determination of Hg2+, Cu2+, and Fe3+ using a cellulose paper-based sensor and UV–vis method with silver nanoparticles synthesized with S. mammosum 使用纤维素纸基传感器和紫外-可见光法,结合用 S. mammosum 合成的银纳米粒子,快速、低成本地测定 Hg2+、Cu2+ 和 Fe3+
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100680
Fernanda Pilaquinga , Jeroni Morey , Paulino Duel , Gabriela S. Yánez-Jácome , Esthefanía Chuisaca-Londa , Karen Guzmán , Jazel Caiza , Melanny Tapia , Alexis Debut , Karla Vizuete , María de las Nieves Piña
{"title":"Rapid, low-cost determination of Hg2+, Cu2+, and Fe3+ using a cellulose paper-based sensor and UV–vis method with silver nanoparticles synthesized with S. mammosum","authors":"Fernanda Pilaquinga ,&nbsp;Jeroni Morey ,&nbsp;Paulino Duel ,&nbsp;Gabriela S. Yánez-Jácome ,&nbsp;Esthefanía Chuisaca-Londa ,&nbsp;Karen Guzmán ,&nbsp;Jazel Caiza ,&nbsp;Melanny Tapia ,&nbsp;Alexis Debut ,&nbsp;Karla Vizuete ,&nbsp;María de las Nieves Piña","doi":"10.1016/j.sbsr.2024.100680","DOIUrl":"10.1016/j.sbsr.2024.100680","url":null,"abstract":"<div><p>As water effluents are often highly contaminated with metals, having a quick and cost-effective method of analysis is crucial. This study used the supernatant derived from the green synthesis of silver nanoparticles (AgNPs) with <em>Solanum mammosum</em> to detect mercury, copper, and iron with a low-cost cellulose paper-based sensor and a rapid colorimetric method applying ultraviolet–visible spectroscopy (UV–Vis). AgNPs in two precursor concentrations using silver nitrate, 1 mM (17.4 ± 9 nm) and 50 mM (and 22 ± 8.1 nm), were utilized to assess the efficacy of the analysis and removal of Hg<sup>2+</sup>, Cu<sup>2+</sup>, and Fe<sup>3+</sup> from contaminated water. Cellulose paper-based sensor showed limits of detection (LODs) for Hg<sup>2+</sup> of 2.46 and 123 μM using AgNPs at concentrations of 1 and 50 mM, respectively. For Cu<sup>2+</sup>, the LODs were 55 and 2750 μM, and for Fe<sup>3+</sup>, the LODs were 49  and 2470 μM using the respective concentrations. To differentiate and detect the cations with the naked eye, a potassium iodide and potassium ferrocyanide (1:1) aqueous solution was used, producing a yellow, pink, and blue color for Hg<sup>2+</sup>, Cu<sup>2+</sup>, and Fe<sup>3+</sup>, respectively. Additionally, the titration curves of Hg<sup>2+</sup>, Fe<sup>3+</sup>, and Cu<sup>2+</sup> were examined by UV–Vis using the supernatant liquid. The LODs for the UV–Vis method using AgNPs at a concentration of 1 mM were 1.50 μM for Hg<sup>2+</sup>, 10.7 μM for Cu<sup>2+</sup>, and 4.33 μM for Fe<sup>3+</sup>, while the LODs for AgNPs at 50 mM were 5.75, 27.6, and 15 μM for Hg<sup>2+</sup>, Cu<sup>2+</sup>, and Fe<sup>3+</sup>, respectively. Furthermore, these nanoparticles were utilized to assess the efficacy of the removal of Hg<sup>2+</sup>, Cu<sup>2+</sup>, and Fe<sup>3+</sup> from contaminated water. Removal efficiency with the solid 50 mM AgNPs was analyzed via flame absorption spectrophotometry; values over 95% were obtained for the three ions. The results underscore the effectiveness of a green synthesis approach to generating AgNPs, enabling efficient and economical cation analysis and water decontamination.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100680"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221418042400062X/pdfft?md5=c04cacbc1ad844b5bf1a9eae761103e1&pid=1-s2.0-S221418042400062X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142048299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring nanotechnology in forensic investigations: Techniques, innovations, and future prospects 探索法医调查中的纳米技术:技术、创新和未来前景
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100674
Muhammad Farhat Ullah , Yousaf Khan , M. Ijaz Khan , Barno Sayfutdinovna Abdullaeva , M. Waqas
{"title":"Exploring nanotechnology in forensic investigations: Techniques, innovations, and future prospects","authors":"Muhammad Farhat Ullah ,&nbsp;Yousaf Khan ,&nbsp;M. Ijaz Khan ,&nbsp;Barno Sayfutdinovna Abdullaeva ,&nbsp;M. Waqas","doi":"10.1016/j.sbsr.2024.100674","DOIUrl":"10.1016/j.sbsr.2024.100674","url":null,"abstract":"<div><p>This work thoroughly reviews nanotechnology's enormous impact on forensic investigations. Various forensic science applications, including explosives detection, chemical warfare agent analysis, latent print visualization, and DNA detection, have been made possible by the unique features of nanotechnology. Rapid and accurate results, simplified analysis processes, and increased sensitivity in evidence identification have all been made possible by its integration. By developing sophisticated nanosensors, nanomanipulators, and nanoimaging instruments, nanotechnology research has also transformed the field of criminal investigation. It has improved forensic methods like document analysis, dating bloodstains, and explosive detection. Nanotechnology holds the potential for more effective investigations and a revolutionary future in forensic science despite difficulties like standardization and expense. To fully realize the potential of nanotechnology for advancing forensic investigations and upholding justice, collaborative efforts and proactive solutions are required. This review provides in-depth knowledge of nanotechnology's function in forensic science and potential future applications.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100674"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000564/pdfft?md5=4c2b3d3104b4b23a2335e2ebb1df4585&pid=1-s2.0-S2214180424000564-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141939686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screen-printed carbon electrode functionalized with AuNPs-cysteamine self-assembled monolayers for enzymatic uric acid detection in non-invasive samples. 以 AuNPs-半胱胺自组装单层为功能化的丝网印刷碳电极,用于无创样本中的酶尿酸检测。
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100677
Héctor David Hernández , Rocio B. Dominguez , Juan Manuel Gutiérrez
{"title":"Screen-printed carbon electrode functionalized with AuNPs-cysteamine self-assembled monolayers for enzymatic uric acid detection in non-invasive samples.","authors":"Héctor David Hernández ,&nbsp;Rocio B. Dominguez ,&nbsp;Juan Manuel Gutiérrez","doi":"10.1016/j.sbsr.2024.100677","DOIUrl":"10.1016/j.sbsr.2024.100677","url":null,"abstract":"<div><p>Uric acid (UA) is a relevant biomarker that at abnormal levels could provide information for the timely diagnosis of chronic-degenerative diseases, such as Diabetes mellitus, cardiovascular deficiencies or gut. This work presents a simple surface functionalization of screen-printed carbon electrodes (SPCE) with cysteamine self-assembled monolayers (SAMs) assembled over electrodeposited gold nanoparticles (AuNPs). The modification allowed the immobilization of uricase enzyme, preserving its biocatalytic activity and resulting in sensitive and selective UA detection. The developed biosensor device exhibited a linear detection range from 100 μM – 1000 μM, a sensitivity of 6.622 nA/μM and a limit of detection (LOD) of 4.6 μM with selectivity to UA molecules over common interfering analytes. When evaluated in urine samples, the analytical capabilities of the PTSPCE/AuNPS/SAMs/Uox biosensor remained, achieving an average recovery rate of 126.91%. The obtained analytical parameters proved to be competitive when utilizing non-invasive fluids, suggesting the possibility of conducting detection assays with potential clinical applications using an implemented electrochemical biosensor through a simple, flexible, and reproducible methodology.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100677"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221418042400059X/pdfft?md5=cf2494735990680abaa07c6cf1157b5f&pid=1-s2.0-S221418042400059X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel high-sensitivity sensor with asymmetric elliptical shaped exposed core and gold coating for sucrose and chemical concentration detection 用于蔗糖和化学浓度检测的新型高灵敏度传感器,具有非对称椭圆形裸露核心和金涂层
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100679
Tanvir Hossain , Md. Arafat Rahman , Md. Rifat Rahman , Tanvir Ahmed
{"title":"A novel high-sensitivity sensor with asymmetric elliptical shaped exposed core and gold coating for sucrose and chemical concentration detection","authors":"Tanvir Hossain ,&nbsp;Md. Arafat Rahman ,&nbsp;Md. Rifat Rahman ,&nbsp;Tanvir Ahmed","doi":"10.1016/j.sbsr.2024.100679","DOIUrl":"10.1016/j.sbsr.2024.100679","url":null,"abstract":"<div><p>The article introducing an innovative exposed core SPR biosensor employing an asymmetrical elliptic air hole PCF known for remarkable sensitivity. Gold-plated fiber sensor detects changes in refractive index. This sensor effectively covers a RI scale of 1.28 to 1.42 for analytes, showcasing its versatility in simultaneous detection. Taking into account the RI change at the outer surface, attractive sensing implementations such as optimal wavelength sensitivity of 97,000 nm/RIU and optimal amplitude sensitivity of 529.20 RIU<sup>−1</sup> are attained. Furthermore, with a resolution of 9.09 × 10<sup>−6</sup> RIU, a figure in merit of 170 RIU<sup>−1</sup>, an FWHM of 570 nm, and a detection accuracy of 0.0166 nm<sup>−1</sup>, the suggested sensor is impressive. This suggested sensor finds application in monitoring sucrose solutions across a spectrum ranging from 0% to 45% chemical concentration over time. It has an ideal amplitude sensitivity of 530.95 RIU<sup>−1</sup> and an ideal wavelength sensitivity of 10,000 nm/RIU for sucrose solutions at the 40% concentration level. Furthermore, the sensor shows an ideal wavelength sensitivity of 35,000 nm/RIU and an ideal amplitude sensitivity of 793.80 RIU<sup>−1</sup> for the detection of 2-propanol. Nevertheless, beyond sucrose noticing auspicious sensing qualities by the suggested sensor its feasibility for impact fully identifying a range of biochemical and organic samples. As a result, the proposed sensor holds promise as an exemplary choice the realms in biomedical sensing, the detection of lower RI analyses as well as chemical analysis. Streamlining practical application, the sensor's structure incorporates eight elliptical air holes, uncomplicated readily manufactural with existing technologies.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100679"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000618/pdfft?md5=cd4622f7739f0092933261f5d3ca1c94&pid=1-s2.0-S2214180424000618-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142048257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of a handheld electronic nose for real-time poultry freshness assessment 应用手持电子鼻实时评估家禽新鲜度
IF 5.4
Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI: 10.1016/j.sbsr.2024.100685
Patrick Ferrier , Yvonne Spethmann , Birte Claussen , Lawrence Nsubuga , Tatiana Lisboa Marcondes , Simon Høegh , Tugbars Heptaskin , Christian Wiechmann , Horst-Günter Rubahn , Roana de Oliveira Hansen
{"title":"Application of a handheld electronic nose for real-time poultry freshness assessment","authors":"Patrick Ferrier ,&nbsp;Yvonne Spethmann ,&nbsp;Birte Claussen ,&nbsp;Lawrence Nsubuga ,&nbsp;Tatiana Lisboa Marcondes ,&nbsp;Simon Høegh ,&nbsp;Tugbars Heptaskin ,&nbsp;Christian Wiechmann ,&nbsp;Horst-Günter Rubahn ,&nbsp;Roana de Oliveira Hansen","doi":"10.1016/j.sbsr.2024.100685","DOIUrl":"10.1016/j.sbsr.2024.100685","url":null,"abstract":"<div><p>Meat and fish are the most resource-demanding food products with a high carbon footprint. However, worldwide, tons of meat and fish products that are still safe to consume are discarded as waste due to uncertainty about their freshness. This study evaluates the application of a newly developed electronic nose (e-nose) to assess the freshness level of chicken and turkey under regular processing conditions. The device, comprising a micro-cantilever sensor functionalized with a binder selective to the freshness biomarker cadaverine, is crucial in reducing this waste. Upon exposure to cadaverine, the sensor resonance frequency changes as a function of analyte concentration. Standard cadaverine concentrations are measured by High-Performance Liquid Chromatography (HPLC) and associated with the shelf-life estimation determined by sensory and microbial evaluations during an 18-day storage period (5 °C). The findings show that the sensory panel evaluates the meat as unsuitable between days 7 and 9, while bacterial data shows high bacterial levels after day 4. HPLC and e-nose data show increasing cadaverine levels after day 4, correlating well with the bacterial count. The data calibrates the electronic nose, demonstrating its potential as a shelf-life prediction tool, which can assist human sensorial evaluation and significantly reduce food waste.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"45 ","pages":"Article 100685"},"PeriodicalIF":5.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000679/pdfft?md5=74575e97c46486e8e2521735ad35331e&pid=1-s2.0-S2214180424000679-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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