Sensing and Bio-Sensing Research最新文献

筛选
英文 中文
The impact of quantum dot on the SPR detection improvement of molecular interactions between Rap1 interacting factor1 (Rif1) and G4 量子点对 SPR 检测 Rap1 交互因子 1 (Rif1) 和 G4 之间分子交互作用的改进的影响
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100621
Sana Alavi , Hamed Ghadiri , Bahareh Dabirmanesh , Khosro Khajeh
{"title":"The impact of quantum dot on the SPR detection improvement of molecular interactions between Rap1 interacting factor1 (Rif1) and G4","authors":"Sana Alavi ,&nbsp;Hamed Ghadiri ,&nbsp;Bahareh Dabirmanesh ,&nbsp;Khosro Khajeh","doi":"10.1016/j.sbsr.2024.100621","DOIUrl":"10.1016/j.sbsr.2024.100621","url":null,"abstract":"<div><p>The main shortcoming of the Surface Plasmon Resonance (SPR) method is its inability to detect low molecular weight (&lt;400 Da) and dilute samples. Moreover, the study of protein-DNA interactions using SPR is one of the most challenging one. Due to these difficulties, the enhancement of SPR signals has been less explored. According to the proposition that the Rif1 protein can be considered a biomarker in breast cancer, further investigations are needed to understand the mechanism of Rif1 and G4 interaction. For this purpose, we studied different platforms to obtain kinetic data on their interaction and to investigate the increase in the SPR signal using quantum dot (Qdot) nanoparticles. Finally, the nickel-NTA chip was used to immobilize the protein, and the streptavidin was attached to Qdot through the EDC-NHS mechanism to bind the 5′-biotinylated G4 structure that was prepared. Different concentrations of biotinylated-G4 were injected, and the enhancement in the signals was studied by injecting the streptavidin-conjugated Qdots onto the chip. Our results indicate a very low dissociation constant of 6.8 ± 0.9 nM which is in consistent with our previous studies. We could enhance the signals by approximately 6 times which is believed to be due to the high bulk density and refractive index of Qdots.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100621"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000035/pdfft?md5=d5da2b17de6466b2f49b6f961a92a90c&pid=1-s2.0-S2214180424000035-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139664259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parameters determination (energy, charge, electric field, shape) of output profiles of HAp-collagen-glucose-based double layer capacitors; possibility for diabetes detection 确定基于 HAp-胶原-葡萄糖的双层电容器输出曲线的参数(能量、电荷、电场、形状);检测糖尿病的可能性
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100626
Griselda A. Rivera , Rogelio Rodriguez , Susana Vargas
{"title":"Parameters determination (energy, charge, electric field, shape) of output profiles of HAp-collagen-glucose-based double layer capacitors; possibility for diabetes detection","authors":"Griselda A. Rivera ,&nbsp;Rogelio Rodriguez ,&nbsp;Susana Vargas","doi":"10.1016/j.sbsr.2024.100626","DOIUrl":"10.1016/j.sbsr.2024.100626","url":null,"abstract":"<div><p>Numerical values of important parameters associated with a piezoelectric material containing an electrolyte and subjected to external stress were obtained; the applied stress produced, almost instantly, induced charges on the material's surface; these charges move the ions of the electrolyte toward the charged surfaces forming the electric double layer EDL; these two charged surfaces give place to the formation, in the interior of the material, of a particular type of capacitor called double layer capacitor DLC. The values of these parameters associated with DLC show interesting and important characteristics: DLC can store considerable amounts of energy and electric charge, as well as high electric fields; these characteristics can explain the extreme sensitivity of the human body to sense extraordinarily small mechanical actions. While the time to induce the charge on the surface τ<sub>e</sub> is instantaneous, the time τ<sub>i</sub> to form EDL is not; this time controls the shape of the output voltage signals. The presence of glucose modifies the piezoelectric signals allowing to use these profiles to diagnose diabetes. Additionally, expressions were obtained for the chemical capacitance C<sub>μ</sub> as a function of voltage and glucose concentration.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100626"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000084/pdfft?md5=95704545f8ff2383ea138863408d93c3&pid=1-s2.0-S2214180424000084-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139664468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of LaF3 passivated porous silicon pH sensor by deep eutectic solvent based novel chemical route 通过基于深共晶溶剂的新型化学路线制备钝化 LaF3 多孔硅 pH 传感器
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100625
Md. Hafijur Rahman , Mohammad Taufiq Alam , Abu Bakar Md. Ismail
{"title":"Fabrication of LaF3 passivated porous silicon pH sensor by deep eutectic solvent based novel chemical route","authors":"Md. Hafijur Rahman ,&nbsp;Mohammad Taufiq Alam ,&nbsp;Abu Bakar Md. Ismail","doi":"10.1016/j.sbsr.2024.100625","DOIUrl":"10.1016/j.sbsr.2024.100625","url":null,"abstract":"<div><p>Lanthanum fluoride (LaF<sub>3</sub>) and other rare-earth halides are commonly used in sensor and optical equipment. A deep eutectic solvent (DES) based LaF<sub>3</sub> passivated porous silicon (PS) sensor for sensing the pH of buffer solution has been fabricated in this research. An electrochemically etched PS structure has been prepared and passivated with novel DES-based LaF<sub>3</sub> to fabricate pH sensor. For the deposition of LaF<sub>3</sub> thin film to create heterostructure devices, a variety of complex and costly processes have been employed. In a quest to find a facile technique to fabricate a pH sensor, this research presents the justification of sensing characteristics of DES-based spin-deposited LaF<sub>3</sub>/PS structure. Energy dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD) analyses both supported the almost stoichiometric and highly crystalline nature of LaF<sub>3</sub>. Scanning electron microscopy (SEM) was used to confirm the uniform morphological structure. The sensing characteristics of fabricated pH sensors have been confirmed by studying the capacitance-voltage (C<img>V) characteristics of prepared structure in a different buffer solution with different pH values. From the experimental results, it was observed that DES-based LaF<sub>3</sub> passivated PS structure shows voltage shift at the inflexion point of C<img>V characteristics for different pH solutions. In light of this, it can be said that a pH sensor for sensing the pH levels of any buffer solution may be fabricated by depositing novel DES-based LaF<sub>3</sub> both inside the pores of PS and on top of it using the spin coating approach.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100625"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000072/pdfft?md5=134db4f97098e00a8853ab638e7c8ba2&pid=1-s2.0-S2214180424000072-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139664466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Embroidered 3D capacitive sensor integrated with bandage for monitoring of volume and type of biofluids 与绷带集成的 3D 电容式绣花传感器,用于监测生物流体的体积和类型
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100634
Saima Qureshi , Goran M. Stojanović , Mitar Simić , Sanja Kojić , Bojan Petrović , Ana Tomas Petrović , Muhammad Umar Aslam Khan
{"title":"Embroidered 3D capacitive sensor integrated with bandage for monitoring of volume and type of biofluids","authors":"Saima Qureshi ,&nbsp;Goran M. Stojanović ,&nbsp;Mitar Simić ,&nbsp;Sanja Kojić ,&nbsp;Bojan Petrović ,&nbsp;Ana Tomas Petrović ,&nbsp;Muhammad Umar Aslam Khan","doi":"10.1016/j.sbsr.2024.100634","DOIUrl":"https://doi.org/10.1016/j.sbsr.2024.100634","url":null,"abstract":"<div><p>Textile based sensors have gained tremendous attention in moisture sensing. Moisture monitoring is crucial in wound healing. To promote the healing process, it is essential to maintain an optimal level of moisture while limiting unnecessary dressing changes. The objective of this research was to test how well a textile moisture sensor can detect moisture from the body and wound fluid when attached to the dressing. To this end, a 3D interdigitated capacitive structure was embroidered with silver conductive threads on the textile substrate, and a bandage was placed in the centre of the multilayer structure. When compared to traditional planar interdigitated structures, the main innovation of the proposed 3D capacitive structure lies in a larger surface area for interaction with the surrounding environment, leading to enhanced sensitivity to changes in capacitance with the respect to the moisture. The 3D structure of the bandage increased the ratio between electrodes and surface area to impact the surface charge sensitivity towards the adsorbed charges of the wound and body fluid. To observe the performance of the sensor, the bandage was exposed to simulated body fluid and wound fluid. Between dry and wet conditions, the sensor can detect capacitance differences of several orders of magnitude. The threshold volume for the 3D bandage was 30 μL to 50 μL, depending on the type of biofluids. The capacitive bandage integration with the inductor was tested at high frequencies (1–400 MHz). The shift in impedance was observed for the tested fluids. Finally, to compare sensing properties of the proposed structure against the previously reported designs, a bandage sensitivity was checked for three different configurations: (a) the proposed 3D bandage, (b) a 2D bandage, composed of textile substrate with both electrodes embroidered on top of bandage, and (c) classical interdigital structure without bandage composed of textile with embroidered electrodes on the top of it. The sensitivity of the 3D bandage for simulated body fluid and wound fluid is &gt;6.6% and 7.4%, respectively, higher than the other two structures. The integration of the proposed textile-based sensor into a bandage could facilitate wound care and have a significant impact on efficacy for patients.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100634"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000163/pdfft?md5=8e5ddb4860e19eada6da1764b49b2c3c&pid=1-s2.0-S2214180424000163-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140000300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electronic nose coupled with artificial neural network for classifying of coffee roasting profile 电子鼻结合人工神经网络对咖啡烘焙特征进行分类
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100632
Suryani Dyah Astuti , Ihsan Rafie Wicaksono , Soegianto Soelistiono , Perwira Annissa Dyah Permatasari , Ahmad Khalil Yaqubi , Yunus Susilo , Cendra Devayana Putra , Ardiyansyah Syahrom
{"title":"Electronic nose coupled with artificial neural network for classifying of coffee roasting profile","authors":"Suryani Dyah Astuti ,&nbsp;Ihsan Rafie Wicaksono ,&nbsp;Soegianto Soelistiono ,&nbsp;Perwira Annissa Dyah Permatasari ,&nbsp;Ahmad Khalil Yaqubi ,&nbsp;Yunus Susilo ,&nbsp;Cendra Devayana Putra ,&nbsp;Ardiyansyah Syahrom","doi":"10.1016/j.sbsr.2024.100632","DOIUrl":"10.1016/j.sbsr.2024.100632","url":null,"abstract":"<div><p>Coffee known for its diverse aromas shaped by postharvest treatments, particularly the roasting process, plays a pivotal role in determining the quality of the brewed beverage. This study focuses on classifying the aroma of Arabica coffee beans based on roasting temperature, employing an electronic nose equipped with a TGS gas array sensor. The classification methodology integrates deep learning through an artificial neural network (ANN), along with a calculation analysis utilizing the Pearson correlation coefficient. Raw Robusta coffee beans were subjected to five distinct roasting treatments (185 °C, 195 °C, 205 °C, 215 °C, and 225 °C), resulting in light roasts, light to medium roasts, medium to dark roasts, medium to dark roasts, and dark roasts. The repeatability test affirms the TGS sensor's reliability, exhibiting a standard deviation (STD) below 20%. Notably, the TGS 2612 and TGS 2611 sensors, dedicated to odor detection, demonstrated excellent validity with an STD below 10% across various roasting temperatures. Classification results from deep learning cross-validation showcase impressive accuracy: 98.2% for Light Roasts, 98.4% for Light to Medium Roasts, 98.8% for Medium Roasts, 97.8% for Medium Roasts, and 95.9% for Dark Roasts. In conclusion, this study reveals that the <em>E</em>-nose, utilizing the TGS gas sensor array with deep learning analysis, effectively detects and classifies coffee types based on roasting time with high accuracy.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100632"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221418042400014X/pdfft?md5=f4975afc65180a2085792fef1bd77b89&pid=1-s2.0-S221418042400014X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139921883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copper nanoclusters modified molybdenum disulfide quantum dots probe for sensitive detection of tetracycline 用于灵敏检测四环素的纳米铜簇修饰二硫化钼量子点探针
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100628
Xiaoxue Tang , Haonan Chi , Zijian Jia , Jingxue Lv , Yuguang Lv , Jiang Wu
{"title":"Copper nanoclusters modified molybdenum disulfide quantum dots probe for sensitive detection of tetracycline","authors":"Xiaoxue Tang ,&nbsp;Haonan Chi ,&nbsp;Zijian Jia ,&nbsp;Jingxue Lv ,&nbsp;Yuguang Lv ,&nbsp;Jiang Wu","doi":"10.1016/j.sbsr.2024.100628","DOIUrl":"10.1016/j.sbsr.2024.100628","url":null,"abstract":"<div><p>By combining molybdenum disulfide quantum dots (MoS<sub>2</sub> QDs) synthesized using a facile hydrothermal method with copper nanoclusters (Cu NCs), copper-ion-modified molybdenum disulfide probes (Cu-MoS<sub>2</sub> QDs) were obtained, enabling sensitive detection and specific recognition of tetracycline (TET). The synthesized probes were characterized using techniques such as fourier-transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and scanning electron microscopy (SEM). The fluorescence values of the probes and TET after their reaction at different concentrations were used to calculate a detection limit of 30 nM for the synthesized probes. The recovery rate of actual samples reached a high value of 95.70%, with a relative standard deviation below 2.00%, demonstrating excellent accuracy and precision. The probe exhibited high selectivity towards TET. The accuracy is maximized when the concentration of the probe is 4.50 × 10<sup>−5</sup> mol/L, indicating enhanced performance of the molybdenum disulfide probe after copper ion modification and obtaining favorable detection outcomes. This probe holds great potential in enhancing the safety of animal-derived food, ensuring public health, and preserving water resources.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100628"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000102/pdfft?md5=8ad8af1d82359d9e54c0e9a4929dbf01&pid=1-s2.0-S2214180424000102-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139819557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The necessity of nanotechnology in Mycoplasma pneumoniae detection: A comprehensive examination 纳米技术在肺炎支原体检测中的必要性:全面考察
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100631
Amir Matini, Seyed Morteza Naghib
{"title":"The necessity of nanotechnology in Mycoplasma pneumoniae detection: A comprehensive examination","authors":"Amir Matini,&nbsp;Seyed Morteza Naghib","doi":"10.1016/j.sbsr.2024.100631","DOIUrl":"https://doi.org/10.1016/j.sbsr.2024.100631","url":null,"abstract":"<div><p><em>Mycoplasma pneumoniae</em> (MP) is a prominent etiological agent of bronchitis and community-acquired pneumonia. MP, the smallest prokaryotes that are wall-less, free-living, and capable of self-replication, are present in more than 200 species of arthropods, animals, and humans. The swift advancement of nanotechnology has facilitated the utilization of a wide range of nanomaterials in constructing effective biosensing platforms that can detect a variety of target analytes. Nanomaterials possess unique magnetic, optical, and electronic properties and a high ratio of surface area to volume. These attributes enable the manipulation and control of these materials through the covalent or noncovalent attachment of recognition moieties. This has generated possibilities for detecting pathogenic microbes that were hitherto unattainable. Regulating the dimensions and composition of the nanomaterials' surfaces can substantially enhance the analytical capabilities of nanomaterials used in assays. As a result, the identification of pathogenic bacteria at the location of the incident can be accomplished swiftly and with minimal sample volumes required to ensure public safety. Assays utilizing nanomaterials offer numerous advantages over traditional pathogen detection methods. These include cost-effectiveness, rapidity, and exceptional precision, mainly when applied to high-throughput screening processes. Furthermore, these assays do not require labels and provide real-time responses. Moreover, they adhere to the standards and regulations set forth by regulatory agencies, hospitals, and the food industry. Nonetheless, obstacles exist in the detection of MP. The persistent difficulty in diagnosing pneumonia caused by MP is attributable to the absence of a sensitive, specific, and rapid detection method. Early-stage MP infections are frequently misdiagnosed due to the absence of distinct clinical and imaging features and atypical symptoms. In addition to serological tests, PCR and rapid culture derived from pharynx samples are the principal laboratory diagnostic techniques. Rapid antigen assays are another example. In this review, various nanotechnology-based methods for detecting MP are examined. Although applying nanotechnology to the detection of MP has yielded encouraging results, obstacles remain to be resolved. Further research is necessary to optimize these nanotechnology-based detection methods' sensitivity, specificity, and velocity.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100631"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000138/pdfft?md5=1979a7159ba5f6dfb62f725090b4e1f0&pid=1-s2.0-S2214180424000138-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel biosensor for highly sensitive detection of serum albumin in artificial human urine using CuNPs@AG 利用 CuNPs@AG 高灵敏度检测人造人体尿液中血清白蛋白的新型生物传感器
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100633
Awaz Sayfallah Sami , Sabah Subhi Ismael Barani , Rzgar Farooq Rashid , Samie Yaseen Sharaf Zeebaree , Aymn Yaseen Sharaf Zeebaree , Osama Ismail Haji Zebari , Ali Mousa Ali , Khalaf Simo Ilyas , Falah Hasan Biso , Muhammad Mirhaj Issa
{"title":"Novel biosensor for highly sensitive detection of serum albumin in artificial human urine using CuNPs@AG","authors":"Awaz Sayfallah Sami ,&nbsp;Sabah Subhi Ismael Barani ,&nbsp;Rzgar Farooq Rashid ,&nbsp;Samie Yaseen Sharaf Zeebaree ,&nbsp;Aymn Yaseen Sharaf Zeebaree ,&nbsp;Osama Ismail Haji Zebari ,&nbsp;Ali Mousa Ali ,&nbsp;Khalaf Simo Ilyas ,&nbsp;Falah Hasan Biso ,&nbsp;Muhammad Mirhaj Issa","doi":"10.1016/j.sbsr.2024.100633","DOIUrl":"10.1016/j.sbsr.2024.100633","url":null,"abstract":"<div><p>Detecting early signs of disease can significantly mitigate the risk of severe consequences. Chronic kidney disease (CKD), stemming from various underlying conditions like diabetes mellitus, high blood pressure, obesity, and heart disease, manifests as an impairment in the kidneys' ability to efficiently filter blood. Consequently, a small amount of the protein albumin might be excreted into the urine. In this study, we have developed a novel biosensor utilizing copper nanoparticles to identify even trace levels of albumin in urine samples. Unlike conventional immunoassay methods, our biosensor doesn't rely on antibodies for its creation. By utilizing gum tree as a stabilizing agent, we've successfully synthesized the copper nanosensor, achieving distinct optical properties and prolonged stability. This method allowed for the precise quantification of bovine serum albumin (BSA) under optimized conditions. To perform quantitative analysis, we established a calibration curve by plotting the variations in absorbance at 580 nm between the sample and the blank. This assay effectively detected albumin within the concentration range of 25 to 250 mg/L (with an R<sup>2</sup> value of 0.98), and it exhibited a low limit of detection (LOD) at 6.5 mg/L. Notably, CuNPs demonstrated excellent specificity towards albumin. Moreover, we successfully applied this developed method for the rapid screening of albumin in synthetic and authentic urine samples, achieving recovery percentages ranging from 90% to 104% using UV–visible spectrometry. Overall, this colorimetric method holds significant promise for on-site albumin detection, offering high accuracy, exceptional selectivity, and minimal reagent consumption.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100633"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000151/pdfft?md5=2a5f69eecf602f07b744080ce8e2dd44&pid=1-s2.0-S2214180424000151-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140019615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrochemical bio-sensor of caffeine in food beverages on using silver vanadium oxide decorated in graphitic carbon nitride (AgVO@g-CN) Nano composite modified glassy carbon electrode 使用氮化石墨碳中装饰的氧化银钒(AgVO@g-CN)纳米复合改性玻璃碳电极对食品饮料中的咖啡因进行电化学生物传感器分析
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2024-02-01 DOI: 10.1016/j.sbsr.2024.100637
V. Vinothkumar , A. Poongan , Abhishek Mandal , P. Venkatesh
{"title":"Electrochemical bio-sensor of caffeine in food beverages on using silver vanadium oxide decorated in graphitic carbon nitride (AgVO@g-CN) Nano composite modified glassy carbon electrode","authors":"V. Vinothkumar ,&nbsp;A. Poongan ,&nbsp;Abhishek Mandal ,&nbsp;P. Venkatesh","doi":"10.1016/j.sbsr.2024.100637","DOIUrl":"10.1016/j.sbsr.2024.100637","url":null,"abstract":"<div><p>The silver vanadate AgVO@g-CN was synthesized by the Co-precipitation method for the first time. The electrocatalytic potential of the AgVO@g-CN nanocomposite is investigated using cyclic voltammetry and differential pulse voltammetry to detect caffeine (CAF). The linear relationship between peak current and CAF concentration has been determined to be in the 6.5 to 255 μM wide linear range, with a lower detection limit of 0.038 μM. The sensitivity of produced electrode was 5.87 μAμM<sup>−1</sup> cm<sup>−1</sup>. The successful application of the modified AgVO@g-CN nanocomposite electrode for CAF detection demonstrates operational stability, and the novel technique displayed good repeatability and reproducibility. Caffeine levels in commercial coffee, Red Bull, and Coca-Cola were successfully determined using the proposed sensor. The results obtained clearly show the capability of sensing and possible application of AgVO@g-CN nanocomposite for real-time electrochemical detection of CAF.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100637"},"PeriodicalIF":5.3,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180424000199/pdfft?md5=a30202865f8f1ee01f2ccd059ccd62e3&pid=1-s2.0-S2214180424000199-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140019775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Numerical analysis of a metal-insulator-metal waveguide-integrated magnetic field sensor operating at sub-wavelength scales 以亚波长尺度工作的金属-绝缘体-金属波导集成磁场传感器的数值分析
IF 5.3
Sensing and Bio-Sensing Research Pub Date : 2023-12-27 DOI: 10.1016/j.sbsr.2023.100618
Mohammad Ashraful Haque , Rummanur Rahad , Md. Omar Faruque , Md Sadi Mobassir , Rakibul Hasan Sagor
{"title":"Numerical analysis of a metal-insulator-metal waveguide-integrated magnetic field sensor operating at sub-wavelength scales","authors":"Mohammad Ashraful Haque ,&nbsp;Rummanur Rahad ,&nbsp;Md. Omar Faruque ,&nbsp;Md Sadi Mobassir ,&nbsp;Rakibul Hasan Sagor","doi":"10.1016/j.sbsr.2023.100618","DOIUrl":"10.1016/j.sbsr.2023.100618","url":null,"abstract":"<div><p>This article introduces a novel plasmonic magnetic field sensor (MFS) that utilizes a Metal-Insulator-Metal (MIM) waveguide configuration with a W-shaped cavity filled with magnetic fluid (MF). The MFS's unique design combines the advantages of plasmonic sensing, offering a promising solution for the detection of magnetic field strength. It operates based on the inherent properties of surface plasmon polaritons and the magneto-optical properties of MF, resulting in a shift in resonant wavelength. The performance of the proposed MFS has been investigated through numerical calculation employing the finite element method (FEM). Remarkably, the MFS exhibits a maximum magnetic field sensitivity of 49.11 pm/Oe, covering a detection range from 33 Oe to 200 Oe. The recorded figure of merit (FOM) and Q-factor of the MFS are 18.39 and 18.4 respectively, attesting to its high performance and reliability. This innovation has the potential to revolutionize fields such as navigation, medical diagnostics, and robotics technologies by seamlessly integrating optical sensing into traditional devices. The proposed sensor's excellent performance, compact size, and cost-effectiveness position it as a promising technology for widespread adoption, contributing to advancements in magnetic field sensing across scientific, industrial, and technological domains.</p></div>","PeriodicalId":424,"journal":{"name":"Sensing and Bio-Sensing Research","volume":"43 ","pages":"Article 100618"},"PeriodicalIF":5.3,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214180423000703/pdfft?md5=715b6874aec420c5078c6de2de205743&pid=1-s2.0-S2214180423000703-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139053637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信