Science of the Total Environment最新文献

{"title":"Meta-analysis reveals the effectiveness and best practices for the iconic Mediterranean seagrass restoration","authors":"Arianna Pansini ,&nbsp;Manuel Berlino ,&nbsp;Maria Cristina Mangano ,&nbsp;Gianluca Sarà ,&nbsp;Giulia Ceccherelli","doi":"10.1016/j.scitotenv.2025.179325","DOIUrl":"10.1016/j.scitotenv.2025.179325","url":null,"abstract":"<div><div>Seagrass forest restoration programs have become a global priority to reverse their decline and regain their ecosystem services. However, defining the restoration effectiveness has remained controversial, probably due to the wide selection of procedures experienced mainly on short-term periods and local scales. Here, scientific literature from 40 years of experience on experimental works and active restoration interventions of the Mediterranean foundation seagrass <em>Posidonia oceanica</em> has been systematically summarized through a meta-analysis. Twenty-five variables concerning the characteristics of the site selection, procedural context, and plant performance evidenced the best practices for the seagrass restoration. Results have evidenced the importance of the correct selection of the donor and receiving site, the use of plagiotropic cuttings bearing at least three shoots, and the need of monitoring the total extent of restored area for long term periods, considering more than one plant trait to define the plant performance. Higher biological levels should be also considered to estimate the recovery of the habitat structure and ecosystem functioning.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"976 ","pages":"Article 179325"},"PeriodicalIF":8.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Timing since deforestation for pastures implementation in the western Amazon: Impacts on stream water biogeochemistry","authors":"Felipe Rossetti de Paula ,&nbsp;Gabriel Lourenço Brejão ,&nbsp;María Angélica Pérez-Mayorga ,&nbsp;Lilian Casatti ,&nbsp;Silvio Frosini de Barros Ferraz ,&nbsp;Alexandra Montebelo Krusche ,&nbsp;Alex Vladimir Krusche","doi":"10.1016/j.scitotenv.2025.179320","DOIUrl":"10.1016/j.scitotenv.2025.179320","url":null,"abstract":"<div><div>Water quality degradation is a global concern and land use changes is one of the main causes of water pollution globally. In the Brazilian Amazon, large-scale deforestation is mostly associated to pasturelands, with strong implications for soils and stream waters biogeochemistry and resulting in environmental degradation. Studies addressing soil biogeochemistry in Amazonian pastures of different ages documented a consistent pattern of elements peaking on the first years after deforestation, followed by a continuous decrease until reach depletion in older, degraded pastures. The same pattern is expected on the adjacent stream water biogeochemistry due to the land-water connection; however, this issue has not being explored. We assessed how timing since deforestation impacts water biogeochemistry in streams of Rondônia State, Brazil, a region that showed a relatively fast colonization process associated to large-scale deforestation for pasture implementation since 1970. Mapping deforestation from 1984 to 2011 and collecting water samples in 2012 for 41 headwater catchments, we (i) compared water biogeochemistry among streams draining undisturbed catchments with primary forests (PRI) and streams draining pasture catchments deforested mostly in a recent (NEW) and in a distant past (OLD); and (ii) related water biogeochemistry with land use intensity (pasture permanency along years), also considering the effect of covariates (soils, forest cover, and catchment area) in our analysis. Our results indicate that pasture implementation altered the concentrations of ions and nutrients in the stream ecosystem, with distinct water quality impacts between newer and older pastures. In general, the longer the area stayed under pasture use, the larger were the alterations in the water biogeochemistry (lower NO₃⁻, DOC, and DOX and higher Ca²⁺, Mg²⁺, DIC and COND). Pasture degradation is a widespread process in the Amazon and it is strongly associated to increasing deforestation. Thus, pasture reclamation and intensification is urgently necessary to achieve the long-term productivity and sustainability of Amazonian pasturelands, avoiding new deforestation and environmental degradation. Adopting Best Management Practices (riparian forested buffers) is another action to protect water resources in the region.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"976 ","pages":"Article 179320"},"PeriodicalIF":8.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collaborative effects of antimony-arsenic contaminations on microbial communities in the typical antimony mining areas of Southwest China","authors":"Qingying Zhao ,&nbsp;Junsheng Li ,&nbsp;Zhao Tan ,&nbsp;Wenjie Li ,&nbsp;Zemin Zhang ,&nbsp;Xiao Guan ,&nbsp;Jinhua Li","doi":"10.1016/j.scitotenv.2025.179249","DOIUrl":"10.1016/j.scitotenv.2025.179249","url":null,"abstract":"<div><div>Antimony (Sb) and arsenic (As) co-contamination is prevalent in Sb mining areas and poses significant risks to the surrounding ecological environment. However, the extent of this co-contamination and the impact of key environmental variables and long-term exposure on the microbial communities remain poorly understood. Therefore, this study assessed Sb-As levels in three representative antimony mining areas in Southwest China and explored the relationships between microorganisms and environmental variables. The results indicated that the concentrations of soil Sb ranged from 6.90 to 50,794.07 mg/kg and As from 4.56 to 8798.86 mg/kg. The potential ecological risk index (RI) in mining and smelting areas surpassed 260, indicating a significantly high risk level. Sb-As predominantly exist as residual fractions. pH, electrical conductivity (EC), and interactions between Sb-As are critical factors influencing the transformation of their chemical fractions. Sb-As exposure altered the microbial community structure and diversity, with positive correlations dominating the co-network. Spearman correlation, redundancy analysis (RDA), canonical correspondence analysis (CCA), and random forest analysis (RF) indicated that the total concentration of Sb-As, the bioavailable fractions of Sb-As, pH, oxidation-reduction potential (Eh), and EC were the main variables affecting the microbial community. Variation partition analysis (VPA) indicated that Sb-As and their chemical fractions explained more microbial community variation than the physicochemical properties. Moreover, the bioavailable fractions were an even more significant variable influencing the microbial communities than the total concentrations of Sb-As. In-depth research on the ecological impact of Sb-As on microbial communities provides valuable insights for environmental monitoring and management.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179249"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimising node-based strategies for enhanced carbon sequestration in mining cities","authors":"Yunshan Wan ,&nbsp;Mengqiu Cao ,&nbsp;Xiaoling Wang ,&nbsp;Yuxin Jiang ,&nbsp;Menglin Ou ,&nbsp;Chunbo Huang","doi":"10.1016/j.scitotenv.2025.179233","DOIUrl":"10.1016/j.scitotenv.2025.179233","url":null,"abstract":"<div><div>Continuous exploitation of mineral resources has had a significant impact on natural ecosystems. This makes it imperative to address problematic nodes in order to restore and improve ecosystem functions within mining areas. However, only a few studies have systematically discussed how to achieve regional carbon sequestration benefits at the regional level, using optimising node-based strategies and taking the impacts of external risk into account. This study develops ‘structure-risk’ node optimisation strategies that could be employed to improve regional carbon sequestration using ecological network theory. Using Xinzhou City, in Shanxi Province, as a case study, the approach ranks carbon nodes by linking node topology features to the landscape risk index. Our results show that from 2000 to 2020, the network exhibited stronger cohesion (clustering: 0.34 to 0.37; degree: 4.80 to 5.27) but reduced efficiency (closeness: 28.70 to 24.87; path length: 0.49 to 0.52) and key node importance (eigenvector: 2.98 to 2.72). Ecological nodes vary in correlation with ‘structure’ and ‘risk’, and thus require targeted optimisation. Node topology positively correlates with carbon sequestration (<em>p</em> &lt; 0.001) and negatively with risk (p &lt; 0.001), with key-linked nodes being crucial and high-risk areas offering limited storage potential. Subsequently, we delineate the optimisation sequence of these nodes to facilitate the restoration of urban areas impacted by mining. This study contributes to enhancing understanding of the intricate interplay between ecological networks and carbon sequestration dynamics under risk interference, thus providing valuable insights for sustainable urban transformation in mining regions.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179233"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pesticide contamination of small standing water bodies in the agricultural landscape of northeast Germany","authors":"Stefan Lorenz ,&nbsp;Fee Nanett Trau ,&nbsp;Lena C. Ruf,&nbsp;Karin Meinikmann,&nbsp;Kathrin Fisch,&nbsp;Matthias Stähler,&nbsp;Detlef Schenke,&nbsp;Holly Lyon Blevins,&nbsp;Marlen Heinz","doi":"10.1016/j.scitotenv.2025.179250","DOIUrl":"10.1016/j.scitotenv.2025.179250","url":null,"abstract":"<div><div>Lentic small water bodies (LSWBs) play a crucial role in global freshwater ecology. Despite their ecological importance, LSWBs are often overlooked in many conservation strategies and scientific studies. A key problem for these ecosystems is anthropogenic stress, in particular the intensive use of pesticides in agriculture. The present study aimed to investigate the extent and variability of pesticide pollution in LSWBs at large spatial and temporal scales. It aimed to identify which substances are frequently detected in these waters and which have the greatest ecotoxicological impact. The study identified eight common pesticides that were detected in low concentrations in many samples at the regional scale. Nine substances also exceeded regulatory acceptable concentration levels (RACs), indicating potential ecological risks. Nicosulfuron, a widely used herbicide in maize growing areas, posed a particular threat as it frequently exceeded its RACs and is persistent in both soil and water. The constant herbicide contamination over three years in LSWBs shown in this study will most likely lead to cascading ecosystem-level effects by changed trophic interactions and altered habitat quality. Other substances, such as chlorpyrifos and clothianidin are no longer used in agriculture, but still showed similar exceedances of RACs. The study emphasizes that LSWBs are particularly prone to continuous pesticide contamination leading to serious ecological consequences that cannot be detected by one-off sampling, which could hold equally true for LSWBs in other agricultural regions of Germany.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179250"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of pH and salinity on the release of polystyrene microplastics derived dissolved organic matter as revealed by experimental studies and molecular dynamic simulations","authors":"Yue Yin,&nbsp;Zhen Li,&nbsp;Ruotong Li,&nbsp;Beichen Yang,&nbsp;Tinglin Huang,&nbsp;Huan Tang","doi":"10.1016/j.scitotenv.2025.179307","DOIUrl":"10.1016/j.scitotenv.2025.179307","url":null,"abstract":"<div><div>Microplastics-derived dissolved organic matter (MPs-DOM) poses a significant risk to aquatic systems. This study characterized MPs-DOM from polystyrene microplastics (PSMPs) upon photoaging in freshwater and seawater. For pristine PSMPs, plastic additives are the predominant substances in MPs-DOM. As the degree of aging increases, intermediates emerge as the new predominant substances in MPs-DOM. Both higher pH and salinity accelerate the aging of PSMPs and MPs-DOM release. Molecular dynamics simulations align with experiments showing that increased pH and salinity levels enhance the release of MPs-DOM. Interaction energy calculations revealed a link between MPs-DOM release amount and the interaction intensity between PSMPs and MPs-DOM. Generally, MPs-DOM having lower interaction energy with PSMPs is more liable to release, and aging of PSMPs leads to a decrease in their interaction energy with MPs-DOM. For example, the interaction energies in the pH 10 seawater system were slightly lower than those in the pH 7 seawater system. In the pH 7 seawater system, the interaction energy between butyl acetate and PSMPs was −41.97 kJ/mol, while in the pH 10 seawater system, this value was −26.86 kJ/mol. These insights are crucial for assessing the environmental behavior of MPs and MPs-DOM in aqueous environments.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179307"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the environmental, health and economic linkages of traditional tapas in Spain: A cluster and LCA approach","authors":"Cristina Álvarez-Folgueras,&nbsp;Cristina Hidalgo-González,&nbsp;Julio Abad-González,&nbsp;David Pérez-Neira","doi":"10.1016/j.scitotenv.2025.179280","DOIUrl":"10.1016/j.scitotenv.2025.179280","url":null,"abstract":"<div><div>‘Tapas culture’ in Spain is an important gastronomic phenomenon associated with eating out; however, environmental, health and economic information on the tapas themselves is almost non-existent. The main objective of this work is thus to evaluate, in a novel way, the linkages between the environmental impact, health and economic cost of 40 tapas served free of charge with drinks in León. From primary information collected in bars and restaurants and within the LCA framework, we evaluated: a) carbon footprint (CF - farm to fork approach); b) nutritional profiles (kcal, protein, fats) and Nutrient Rich Diet Index (NRD 9.3); c) economic cost and d) eco-efficiency indicators based on different functional units. The weight, kcal content, NRD9.3, CF and average cost of the tapas were estimated as: 0.11 (±0.05) g, 201 (±130) kcal, 640 (±335) points, 0.38 (±0.21) kg CO₂-eq, 0.38 (±0.21) € per tapa. A cluster analysis of these indicators resulted in four groups of tapas according to economic and nutritional variables, such as the level of presence of animal products. Our model shows that in an agroecological scenario (using organic, local and seasonal foods and higher cooking efficiency) it is possible a CF reduction between 6 % and 60 % depending on the tapa analyzed but increasing their average cost. However, this assessment of the environmental/health/economic implications provides scientific evidence of the positive effects of switching to more sustainable and healthy tapas at a reasonable cost increase linked to a change in diet and culinary offerings. This evidence serves as a basis for defending the need to promote actions and public policies to build a more sustainable, healthy, and culturally adapted food system.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"976 ","pages":"Article 179280"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marine food web trophic interaction of trace elements and stable isotopes of carbon and nitrogen in Rabigh lagoon, Red Sea, Saudi Arabia","authors":"Mohammed Othman Aljahdali ,&nbsp;Abdullahi Bala Alhassan","doi":"10.1016/j.scitotenv.2025.179245","DOIUrl":"10.1016/j.scitotenv.2025.179245","url":null,"abstract":"<div><div>The increase in heavy metal pollution in mangrove ecosystems due to anthropogenic activities has been on the increase and has been studied previously. However, there is a need for a better understanding of the use of stable isotopes of carbon (δ¹³C) and nitrogen (δ¹⁵N) to establish trophic levels (TL) and their contamination in the food web. In this study, samples of sediment, mangrove, algae, seagrasses, crustacean, poriferans, echinoderms, molluscs, cnidarian and fishes were collected for determination of trace elements (Fe, Mn, Cu, Zn, Cd, Cr, Pb, Ni and Co) and stable isotopes. Varian 720-ES inductively coupled plasma-optical emission spectrometer (ICP-OES) and Thermo elementary analyser–ConFlo IV–Delta V Advantage mass spectrometer were used for the analysis of metals and stable isotopes respectively. The food web structure of Rabigh lagoon mangrove comprises a group of organisms such as crustacean (crab), porifera (sponges), echinoderm (starfish), mollusc (aquatic snails) and cnidarian (coral) in the second trophic level (TL = 1.0–2.0). For the third trophic level (TL = 2–3), <em>Platycephalus bassensis</em> (TL = 2.96) and <em>Scomber</em> sp. (TL = 2.30) belonging to the taxonomic group fishes are the two organisms in this trophic level. However, from the 9 trace elements determined, only Cd and Pb recorded excessive bioconcentration in the species. In terms of Total Magnification Factor (TMF) and metal concentrations, there was significant biodilution of all trace elements determined in this study except for Pb (TMF = 0.72; <em>p &gt;</em> 0.05) and Co across the extracted food web consisting of molluscs, crustacean and fishes. Biodilution of Pb was not significant across the trophic levels of the food web. This study provides baseline information on the food web structure and transfer of trace elements across the food web of Rabigh mangrove, Red Sea, Saudi Arabia.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179245"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Greywater reuse for irrigation: A critical review of suitability, treatment, and risks","authors":"Muhammed Nimet Hamidi","doi":"10.1016/j.scitotenv.2025.179272","DOIUrl":"10.1016/j.scitotenv.2025.179272","url":null,"abstract":"<div><div>Greywater accounts for approximately 75 % of domestic wastewater and generally contains fewer contaminants than domestic wastewater. Therefore, its treatment and reuse represent a promising approach to supplement irrigation demand. This study comprehensively evaluates the quality characteristics of greywater based on its source, applied treatment methods, and its potential health, environmental, soil, and agricultural impacts. Various physical, chemical, and biological treatment processes have been analysed, with the most commonly employed technologies including membrane bioreactors (MBRs), constructed wetlands, media filtration (sand, activated carbon), disinfection methods (UV, chlorine, ozone), and advanced oxidation processes. The effectiveness of these methods has been assessed concerning the intended reuse application, emphasizing the critical role of disinfection in ensuring safe irrigation use. The health and environmental implications of greywater reuse have been examined, focusing on the risks associated with pathogen contamination, detergent residues, and micropollutants, while also evaluating the efficiency of treatment processes in mitigating these risks. From an environmental perspective, the accumulation of essential nutrients such as nitrogen and phosphorus, the potential for salinity buildup, and alterations in soil microbial balance have been investigated. Regarding soil and agricultural impacts, this study analyzes how greywater reuse influences soil structure (e.g., permeability, infiltration), plant growth responses, and the accumulation of heavy metals. These findings contribute to the development of scientifically grounded recommendations for the safe and sustainable reuse of greywater within water management strategies, promoting its role as an alternative water source for irrigation.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179272"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aged microplastics-induced growth inhibition via DNA damage, GH/IGF-1 and HPT axes disruption in zebrafish larvae","authors":"Qing Ge ,&nbsp;Tong Zheng ,&nbsp;Ping Ding ,&nbsp;Zhenyuan Li ,&nbsp;Xihua Lin ,&nbsp;Xintong Li ,&nbsp;Miao He ,&nbsp;Guocheng Hu","doi":"10.1016/j.scitotenv.2025.179215","DOIUrl":"10.1016/j.scitotenv.2025.179215","url":null,"abstract":"<div><div>The escalating use of microplastics (MPs) has led to the widespread exposure of aquatic organisms. The associated toxicities of MPs may be influenced by photoaging. However, the toxicity of aged MPs at environmentally relevant concentrations to aquatic organisms remains unclear. Therefore, our study focused on assessing the effects of aged polystyrene microplastics (PS-MPs) on the development of zebrafish. Here, using simulated sunlight, we investigated the endocrine and developmental toxicity of embryo-larvae exposed to pristine PS-MPs (1 μm) and aged PS-MPs at environmentally relevant concentrations of 0.1–100 μg/L. The alterations in PS-MPs characteristics using photoaging were investigated through scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The results suggested that photoaging altered physicochemical characteristics of PS-MPs. The assessment of physiological indicators revealed that exposure to aged PS-MPs significantly inhibited the growth of larval zebrafish compared to pristine PS-MPs with endpoints of body length, heartbeat rate and tail coiling frequency. Bioinformatics analyses indicated that aged PS-MPs exposure perturbed the hormones levels (GH, IGF-1, T3 and T4) and gene expression <strong>(</strong>e.g., <em>gh, igf1, trh</em> and <em>ugt1ab)</em> related to growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis, and the hypothalamic-pituitary-thyroid (HPT) axis. Moreover, 8-OHdG levels were significantly altered in zebrafish larvae exposed to aged PS-MPs, and Pearson correlation results showed significant associations between 8-OHdG levels and GH/IGF-1 and HPT axis-related genes. Overall, these results indicated that the growth inhibition of larval was attributed to DNA damage, HPT and GH/IGF axes disruption, providing new insights into the environmental effects and health risks of MPs.</div></div>","PeriodicalId":422,"journal":{"name":"Science of the Total Environment","volume":"975 ","pages":"Article 179215"},"PeriodicalIF":8.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143777341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}