Results in Chemistry最新文献

{"title":"Facile green diversity-oriented synthesis, molecular docking, and cytotoxicity evaluation of quinoline -triazole appended peptidomimetics as inhibitors of human breast cancer cell line MCF-7","authors":"K. Ramya ,&nbsp;Seena Chakko ,&nbsp;V.S. Shinu ,&nbsp;Davis Varghese ,&nbsp;Ron Joy Pullukkara ,&nbsp;S. Arun","doi":"10.1016/j.rechem.2025.102172","DOIUrl":"10.1016/j.rechem.2025.102172","url":null,"abstract":"<div><div>The synthesis of quinoline-based drugs has significant interest from researchers due to their broad spectrum of biological activities. In this context, a concise approach for the synthesis of quinoline-functionalized hybrid peptidomimetics is described. The peptidomimetics are constructed based on a recombinant approach via Iqbal multicomponent coupling strategy and click chemistry and were linked via copper (I) catalysed [3 + 2] azide-alkyne cycloaddition. The peptidomimetics showed exceptional inhibitory properties for CDK2 protein which is responsible for many malignancies and also showed remarkable cytotoxicity against human breast cancer cell line MCF-7. The IC₅₀ value (8 μM) and binding affinity (−10.2 Kcal/mol) found for <strong>4b</strong> against MCF-7 cells are hopeful for the development of potential anticancer drugs based on these new scaffolds.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102172"},"PeriodicalIF":2.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical properties of bioactive bioplastics based on cellulose from coffee and cocoa by-products","authors":"Robin Oblitas ,&nbsp;Luz Quispe-Sanchez ,&nbsp;Grobert Guadalupe ,&nbsp;Elgar Hernandez Diaz ,&nbsp;Segundo Oliva ,&nbsp;Jorge R. Diaz-Valderrama ,&nbsp;Ives Yoplac ,&nbsp;Cristina Valencia-Sullca ,&nbsp;Segundo G. Chavez","doi":"10.1016/j.rechem.2025.102201","DOIUrl":"10.1016/j.rechem.2025.102201","url":null,"abstract":"<div><div>Plastic pollution has become a critical environmental issue due to the extensive use of petroleum-derived plastics, which persist in ecosystems and pose significant challenges to sustainability. This study evaluated the physicochemical properties of bioactive bioplastics made from cellulose extracted from coffee by-products (spent coffee grounds) and cocoa (pods), which were proposed as a sustainable alternative to mitigate the environmental impact of petroleum-derived plastics. The formulation of the bioplastics involved varying proportions of cellulose (1, 3, and 6 %) in combination with bioactive cacao extracts (0.05 % and 0.15 % <em>w</em>/<em>v</em>). A comprehensive array of physicochemical properties was analyzed, encompassing parameters such as color change, whiteness index, water activity, solubility, transparency, flexibility, antioxidant capacity, and biodegradation. The results demonstrated that the bioplastics with 3 % cocoa pod cellulose (CMC) and 0.05 % bioactive extract exhibited the highest whiteness index (86.9) and the most excellent flexibility (32.24 N). In contrast, formulations comprising 6 % CMC exhibited reduced water activity (0.49). Bioplastics containing 1 % coffee cellulose (PC) and 0.15 % bioactive extract demonstrated a high antioxidant capacity (0.38 mgTE/L). Furthermore, it was observed that an increase in cellulose content led to a decrease in the biodegradation rate, with the control achieving 98 % degradation within 35 days. This study provides fundamental information for designing bioplastics with specific properties, thereby promoting the development of more sustainable and environmentally friendly packaging technologies.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102201"},"PeriodicalIF":2.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of N3-substituted-quinazoline-2,4(1H,3H)-diones via CuI-catalyzed coupling of 2-iodobenzamides with potassium cyanate","authors":"Ali Nasirpour ,&nbsp;Zarrin Ghasemi ,&nbsp;Seyed Abolfazl Hosseini-Yazdi ,&nbsp;Morgane Poupon ,&nbsp;Cinthia Antunes Correa","doi":"10.1016/j.rechem.2025.102204","DOIUrl":"10.1016/j.rechem.2025.102204","url":null,"abstract":"<div><div>Herein, we disclosed the synthesis of <em>N</em>3-substituted-quinazoline-2,4(1<em>H</em>,3<em>H</em>)-diones via the consecutive copper-catalyzed coupling/annulation of 2-iodobenzamides and KOCN. This transformation is characterized by the in situ-generation of arylisocyante through C(<em>sp</em>^<em>2</em>)-N(<em>sp</em>^<em>2</em>) bond formation, which enriches the library of preparation quinazolindiones. Moreover, it is worth noting that replacing the iodo group with bromo also produced a comparable yield of the corresponding quinazolinedione derived under the present conditions.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102204"},"PeriodicalIF":2.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, crystal structure, DFT calculations, and molecular docking of N-(4-bromophenyl)pyridine-2-carboxamide palladium(II) complexes","authors":"Pinky N. Mjwara ,&nbsp;Eric O. Akintemi ,&nbsp;Siphamandla Sithebe ,&nbsp;Hadley S. Clayton ,&nbsp;Tshephiso R. Papo","doi":"10.1016/j.rechem.2025.102194","DOIUrl":"10.1016/j.rechem.2025.102194","url":null,"abstract":"<div><div>A novel palladium(II) complex, ([N-(4-bromophenyl)pyridine-2-carboxamidato]-(chloro)-(pyridine)‑palladium, <strong>C2</strong>) was synthesized from an aqueous solution of potassium tetrachloropalladate, pyridine and the <em>N</em>-<!--> <!-->(4-<!--> <!-->bromophenyl)<!--> <!-->pyridine-2-carboxamide ligand. Single crystal X-ray crystallography analysis reveals that the asymmetric units of C₁₇H₁₅BrClN₃O₂Pd belong to the orthorhombic crystal system with the Pbca space group. The experimentally determined structure of <strong>C2</strong> was examined and compared to a previously synthesized analogous bis[N-(4-bromophenyl)pyridine-2-carboxamidato]palladium complex (<strong>C1</strong>) by density functional theory (DFT) and molecular docking studies. DFT b3lyp/3-21g method gave reasonably low optimization energies and band energy value of ∼3.2 eV for both complexes, suggesting they are chemically reactive. Molecular docking simulations through the docking scores show that <strong>C2</strong> (−121.2 and −119.2 kcal/mol) is more potent than <strong>C1</strong> (−73.1 and −106.6 kcal/mol) against prostate and cervical cancers, while <strong>C1</strong> (−78.5 and −108.3 kcal/mol) is more potent than <strong>C2</strong> (−88.5 and −116.5 kcal/mol) against skin and breast cancer. Some key interacting residues in the binding site of prostate cancer protein include Trp227, Phe306, Phe311, and Tyr317. The cervical cancer protein includes Tyr15, Asp127, Val18 and Glu12. For skin cancer protein, they are Arg223, Glu226, Leu227 and Ile224; and for breast cancer protein are Cys2085, Glu2052, Phe2048, and Gln2082. Generally, the Pd(II) complexes show promising anticancer potential and could potentially be a more effective chemotherapeutic than the standard carboplatin drug.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102194"},"PeriodicalIF":2.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbon nanotubes in brain targeted drug delivery: A comprehensive review","authors":"Sourav Das ,&nbsp;Sukanta Roy ,&nbsp;Subhas Chandra Dinda ,&nbsp;Anirbandeep Bose ,&nbsp;Chinmaya Mahapatra ,&nbsp;Biswajit Basu ,&nbsp;Bhupendra Prajapati","doi":"10.1016/j.rechem.2025.102206","DOIUrl":"10.1016/j.rechem.2025.102206","url":null,"abstract":"<div><div>The treatment of brain diseases remains a significant challenge in modern medicine, primarily due to the restrictive nature of the blood-brain barrier (BBB), which limits drug delivery. Carbon nanotubes (CNTs) have emerged as a promising strategy for overcoming this obstacle, providing an innovative platform for targeted drug delivery to the brain. This review presents a detailed analysis of CNTs as drug carriers, with a particular emphasis on their application in brain tumor treatment. Their unique physicochemical properties, including a high surface area, tunable surface chemistry, and exceptional drug-loading capacity, make them ideal candidates for encapsulating and delivering therapeutic agents with precision. Functionalization with targeting ligands further enhances the specificity of CNTs, enabling drugs to reach brain tumors more effectively while minimizing off-target effects. The review examines advancements in CNT-based drug delivery systems, particularly their role in transporting chemotherapy drugs, nucleic acid-based therapies, and other small molecules across the BBB. It also highlights their potential to improve therapeutic efficacy while reducing systemic toxicity. Furthermore, the challenges and opportunities associated with CNT-based drug delivery, such as safety concerns, regulatory barriers, and clinical translation, are explored. The discussion extends to the development of multifunctional CNT platforms that combine imaging agents with therapeutic payloads, allowing for real-time tumor monitoring and treatment. Ultimately, this review provides insights into the potential of CNTs as carriers for brain-targeted drug delivery, offering a pathway toward more effective and less invasive brain tumor therapies. Understanding current advancements and addressing existing challenges will be crucial for realizing the full potential of CNT-based drug delivery in neuro-oncology.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102206"},"PeriodicalIF":2.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Monte Carlo simulation and quantitative microbial risk approach to investigate seasonal variation of airborne particulate matter and bioaerosols in medical waste management department and wastewater treatment plant of Iranian hospitals","authors":"Mahbubeh Tangestani ,&nbsp;Ahmad Jonidi Jafari ,&nbsp;Majid Kermani ,&nbsp;Roshanak Rezaei Kalantary ,&nbsp;Hossein Arfaeinia","doi":"10.1016/j.rechem.2025.102196","DOIUrl":"10.1016/j.rechem.2025.102196","url":null,"abstract":"<div><div>This study addresses a significant knowledge gap by conducting a thorough analysis of pollutants in hospital environments and utilizing advanced risk assessment models to evaluate their health impacts on workers for the first time. The study aimed to assess the concentration of particulate matter (PM₁_–_2.5, PM_0.5_–₁, PM_0.25_–_0.5, and PM_˂0.25) and bioaerosols (bacteria and fungi) in the air around waste disposal departments and wastewater treatment plants of selected hospitals in Bushehr city, Iran, during different seasons. A probabilistic risk assessment using Monte Carlo simulation and the Disability-Adjusted Life Years (DALYs) model was employed to evaluate the health risks of PM and bioaerosols on workers. The study collected 32 PM samples and 132 bioaerosol samples using a four-stage impactor and a single-stage Anderson sampler, respectively. The results showed that the highest concentration of PM was found in PM₁_–_2.5, measuring 119.4 μg/m³, while bacteria and fungi concentrations were 617 and 756 CFU/m³, respectively. Additionally, larger PM sizes were more prevalent, and bacterial levels exceeded those of fungi in the wards. Waste disposal sections in hospitals exhibited higher pollution levels of PM, bacteria, and fungi compared to wastewater treatment plants, especially during summer. Bioaerosol levels exceeded existing standards in the surrounding air of these departments Risk values surpassed acceptable thresholds, indicating significant health concerns. Sensitivity analysis revealed that concentration (C) and exposure duration (ED) parameters had the most significant impact on worker health assessment.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102196"},"PeriodicalIF":2.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vertex and edge resolvability of some drug structures","authors":"Ayesha Andalib Kiran ,&nbsp;Hani Shaker ,&nbsp;Muhammad Faisal Nadeem ,&nbsp;Bahreselam Sielu Abraha","doi":"10.1016/j.rechem.2025.102180","DOIUrl":"10.1016/j.rechem.2025.102180","url":null,"abstract":"<div><div>Distance-based parameters are crucial in studying drug structures as they help in uniquely identifying and characterizing the molecular structure through the analysis of graph representations, thereby aiding in the understanding of molecular properties and behaviors. A subset of vertex set of a graph is said to be vertex resolving set if no two vertices have same representation w.r.t. the resolving set. the minimum cardinality of the vertex resolving set is called metric dimension. Similarly, if the vertex subset of graph is responsible for uniquely identifying the edges of the graph then it is called edge resolving set, and the minimum cardinality of edge resolving set is called the edge metric dimension. In pharmaceutical research, resolving sets are especially used to identify patterns shared by multiple medications. Medical drugs have been an integral part of human culture since the beginning of time. In this study, we investigated the metric and edge metric dimensions of some significant drug structures namely, Salicylic Acid <span><math><mrow><mo>(</mo><mi>S</mi><msub><mrow><mi>A</mi></mrow><mrow><mn>16</mn></mrow></msub><mo>)</mo></mrow></math></span>, Diazepam <span><math><mrow><mo>(</mo><mi>D</mi><msub><mrow><mi>I</mi></mrow><mrow><mn>33</mn></mrow></msub><mo>)</mo></mrow></math></span>, Lidocaine <span><math><mrow><mo>(</mo><mi>L</mi><msub><mrow><mi>I</mi></mrow><mrow><mn>39</mn></mrow></msub><mo>)</mo></mrow></math></span> and Ibuprofen <span><math><mrow><mo>(</mo><mi>I</mi><msub><mrow><mi>B</mi></mrow><mrow><mn>39</mn></mrow></msub><mo>)</mo></mrow></math></span>. According to our findings, we observed that we have a relation for <span><math><mrow><mo>(</mo><mi>D</mi><msub><mrow><mi>I</mi></mrow><mrow><mn>33</mn></mrow></msub><mo>)</mo></mrow></math></span>, <span><math><mrow><mi>d</mi><mi>i</mi><mi>m</mi><mrow><mo>(</mo><mi>D</mi><msub><mrow><mi>I</mi></mrow><mrow><mn>16</mn></mrow></msub><mo>)</mo></mrow><mo>≥</mo><mi>e</mi><mi>d</mi><mi>i</mi><mi>m</mi><mrow><mo>(</mo><mi>D</mi><msub><mrow><mi>I</mi></mrow><mrow><mn>16</mn></mrow></msub><mo>)</mo></mrow></mrow></math></span>. The metric and edge metric dimension are same for <span><math><mrow><mo>(</mo><mi>S</mi><msub><mrow><mi>A</mi></mrow><mrow><mn>16</mn></mrow></msub><mo>)</mo></mrow></math></span>, <span><math><mrow><mo>(</mo><mi>L</mi><msub><mrow><mi>I</mi></mrow><mrow><mn>39</mn></mrow></msub><mo>)</mo></mrow></math></span> and <span><math><mrow><mo>(</mo><mi>I</mi><msub><mrow><mi>B</mi></mrow><mrow><mn>33</mn></mrow></msub><mo>)</mo></mrow></math></span> but if we compare two different molecules form them, their metric (edge) dimension is not identical. The fact that their metric dimensions are not identical makes it more efficient and effective for molecular structure identification.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102180"},"PeriodicalIF":2.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adsorptive removal of Cr(VI) from aqueous solution using sulfuric acid-treated diatomite","authors":"Sintayehu Shewatatek ,&nbsp;Girma Gonfa ,&nbsp;Sintayehu Mekuria Hailegiorgis ,&nbsp;Belete Tessema","doi":"10.1016/j.rechem.2025.102205","DOIUrl":"10.1016/j.rechem.2025.102205","url":null,"abstract":"<div><div>In this study, diatomite underwent acid treatment and was examined for its capability to adsorb chromium (VI) (Cr (VI)) from water. The diatomite was treated with sulfuric acid (H₂SO₄) in varying concentrations (2–10 M) over different activation times (4–12 h), solid-to-liquid ratios (50–250 g/L), and activation temperatures (60–90). Optimal Cr (VI) removal was achieved with a 4 M H₂SO₄ concentration, an activation time of 10 h, a solid-to-liquid ratio of 50 g/L, and an activation temperature of 90 °C. Both raw diatomite and acid-treated diatomite (TDE) were characterized using scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), Brunauer, Emmett, and Teller (BET), and X-ray diffractometer (XRD). BET analysis showed an increase in surface area from 22.39 m²/g to 34.83 m²/g after treatment. The maximum Cr(VI) removal efficiency of 86.7 % was achieved at pH 2, 0.3 g/100 mL adsorbent dosage, 60 min contact time, and 10 ppm initial Cr(VI) concentration, according to the optimization of adsorption studies that were carried out across varying pH (2−10), adsorbent dosage (0.1–0.5 g/100 mL), contact time (15–75 min), and initial Cr(VI) concentration (10–30 ppm). The Freundlich and Sips isotherm models provided the best description of the adsorption process, revealing heterogeneous surface interactions and a maximum adsorption capacity of 16.395 mg/g. Chemisorption was confirmed as the major mechanism by kinetic analysis, which showed that the pseudo-second-order model fit the data the best. Thermodynamic studies validated the process as spontaneous and endothermic. These findings show that diatomite treated with sulfuric acid is a very efficient adsorbent for removing Cr(VI) from tainted water.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102205"},"PeriodicalIF":2.5,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poly(amidoxime) chelating ligand from pine wood cellulose for eco-friendly toxic metals extraction from water sources","authors":"Md Lutfor Rahman ,&nbsp;Mohd Asyraf Aiman ,&nbsp;Mohd Sani Sarjadi ,&nbsp;Sazmal Effendi Arshad ,&nbsp;Shaheen M. Sarkar ,&nbsp;Sandeep Kumar","doi":"10.1016/j.rechem.2025.102198","DOIUrl":"10.1016/j.rechem.2025.102198","url":null,"abstract":"<div><div>Industrial, domestic, and agricultural activities have significantly contributed to environmental pollution, with heavy metal contamination from wastewater emerging as a critical issue. In this study, nanocellulose was extracted from pine wood and chemically modified via graft copolymerization. Free radicals generated on the cellulose backbone facilitated the grafting of acrylonitrile monomers, resulting in poly(acrylonitrile)-grafted nanocellulose. This intermediate product was further transformed into poly(amidoxime), a chelating polymer ligand specifically designed for heavy metal extraction from aqueous media. Batch adsorption experiments evaluated the removal efficiency of heavy metal ions, including copper (Cu²⁺), iron (Fe²⁺), cobalt (Co²⁺), nickel (Ni²⁺), and lead (Pb²⁺). Analytical results revealed that Cu²⁺ exhibited the highest adsorption capacity of 335 mg/g at pH 6. Other metal ions also showed significant adsorption capacities, including Fe²⁺ (281 mg/g), Co²⁺ (241 mg/g), Ni²⁺ (205 mg/g), and Pb²⁺ (306 mg/g), confirming the polymer's effectiveness in heavy metal removal. Adsorption behavior was analyzed using the Langmuir isotherm model, which assumes monolayer adsorption on a surface with uniformly distributed active sites. The experimental data aligned well with this model, demonstrating predictable and efficient adsorption performance. Reusability studies indicated that the poly(amidoxime) ligand retained its adsorption capacity over six cycles with minimal degradation, highlighting its sustainability. This suggests its potential as a cost-effective and reusable material for heavy metal remediation. By combining high adsorption capacity with reusability, poly(amidoxime) provides a durable and efficient solution for addressing heavy metal contamination in wastewater, significantly contributing to environmental sustainability through improved water treatment methods.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102198"},"PeriodicalIF":2.5,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances of Fiber-reinforced polymer composites for defense innovations","authors":"Mona M. Alzahrani ,&nbsp;Khalid A. Alamry ,&nbsp;Mahmoud A. Hussein","doi":"10.1016/j.rechem.2025.102199","DOIUrl":"10.1016/j.rechem.2025.102199","url":null,"abstract":"<div><div>Fiber-reinforced polymer (FRP) composites have emerged as pivotal materials in defense applications due to their remarkable mechanical properties, lightweight design, and adaptability. This study reviews advancements in FRP composites, highlighting their superior strength-to-weight ratios, and impact resistance, which make them ideal for ballistic protection and aerospace. The review examines a variety of fiber types, including synthetic fibers like glass, carbon, aramid, and UHMWPE, as well as natural fibers focusing on their enhanced mechanical and functional properties achieved through processing techniques. The manufacturing approach of FRP composites occurs through widely recognized methods such as hand lay-up, compression molding, pultrusion, and advanced techniques like additive manufacturing, which have significantly contributed to the advancement of these composites. Furthermore, the incorporation of nanomaterials has transformed FRP composites by enhancing mechanical strength, interfacial bonding, and energy absorption. The study emphasizes the growing importance of hybrid composites and nanotechnology-enhanced materials, which combine multiple fiber types or introduce nano-scale fillers to reduce weight and improve ballistic performance. In particular, applications in body armor, helmets, and aircraft equipment are presented, demonstrating advancements that enhance military protection without compromising mobility. Additionally, issues like cost, recycling restrictions, and performance maintenance in the face of changing threats are addressed; future studies will concentrate on sustainable materials, economical procedures, and cutting-edge protective systems.</div></div>","PeriodicalId":420,"journal":{"name":"Results in Chemistry","volume":"15 ","pages":"Article 102199"},"PeriodicalIF":2.5,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}