Bifidobacteria and Microflora最新文献_第3页

Suppressive Effect of Feeding Yoghurt or Lactose on N-Methyl-N'-Nitro-N-Nitrosoguanidine-Induced Gastric Tumorigenesis in Rats 饲喂酸奶或乳糖对n -甲基- n '-硝基- n -亚硝基胍诱导大鼠胃肿瘤发生的抑制作用

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.9.2_135

Y. Morishita, K. Shiromizu

引用次数: 8

D-Xylonic Acid Utilization by Bifidobacteria 双歧杆菌对d -木糖酸的利用

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.14.1_15

H. Noda, M. Ohsugi

引用次数: 0

Antibacterial Activity and Bacterial Degradation of Linoleic Acid Hydroperoxide 过氧化亚油酸的抑菌活性及细菌降解

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.14.2_67

M. Tsuchida, Y. Morishita

{"title":"Antibacterial Activity and Bacterial Degradation of Linoleic Acid Hydroperoxide","authors":"M. Tsuchida, Y. Morishita","doi":"10.12938/BIFIDUS1982.14.2_67","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.14.2_67","url":null,"abstract":"A comparative study was conducted on the antibacterial activities of linoleic acid hydroperoxide (LAHPO) and linoleic acid (LA) against the intestinal bacteria including 35 strains, and the representative species were examined for lipid degradation activity. Enterobacterial species (Escherichia coli, Proteus mirabilis, Citrobacter sp. and Enterobacter sp.), Lactobacillus species (acidophilus, casei and plantarum), and Enterococcus faecalis generally showed the same levels in susceptibility to LA and LAHPO. Bacteroides species (distasonis, vulgatus and thetaiotaomicron) and Clostridium ramosum were highly resistant against LA but not LAHPO. Staphylococcus species (aureus and epidermidis), Lactobacillus pecies (salivarius and fermentum) and the Grampositive anaerobic bacteria including Clostridium perfringens, Bifidobacterium species (bifidum, infantis, adolescentis, breve, longum, animalis, pseudolongum and thermophilus), Peptostreptococcus productus, and Eubacterium sp. were more susceptible to LAHPO than were the enterobacterial species and E. faecalis although they were more resistant against LAHPO than LA. Eubacterium aerofaciens was more susceptible to LAHPO, but strikingly susceptible to both lipids compared to the other bacterial strains. Thin layer chromatography showed that C. perfringens degrade LAHPO and C. ramosum degrade LA, which was consistent with the resistance of the corresponding species to the fatty acids. A similar trend in the resistance to and degradation of the fatty acids was found with B. adolescentis and B. infantis. Much higher degradation abilities were observed in the live bacterial cells than the heat-killed cells of B. adolescentis, C. perfringens, and E. coli, suggesting that they can enzymatically degrade LAHPO in vitro.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"194 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134157497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Tumor-suppressive effect of a cell wall preparation, WPG, from Bifidobacterium infantis in germfree and flora-bearing mice 婴儿双歧杆菌细胞壁制剂WPG对无菌和带菌小鼠的肿瘤抑制作用

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.10.1_43

S. Tsuyuki, S. Yamazaki, H. Akashiba, H. Kamimura, K. Sekine, T. Toida, M. Saito, T. Kawashima, K. Ueda

{"title":"Tumor-suppressive effect of a cell wall preparation, WPG, from Bifidobacterium infantis in germfree and flora-bearing mice","authors":"S. Tsuyuki, S. Yamazaki, H. Akashiba, H. Kamimura, K. Sekine, T. Toida, M. Saito, T. Kawashima, K. Ueda","doi":"10.12938/BIFIDUS1982.10.1_43","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.10.1_43","url":null,"abstract":"A cell wall preparation (whole peptidoglycan, WPG) derived from Bifidobacterium infantis exhibited antitumor activity when WPG and Meth A cells were mixed and injected subcutaneously (suppression test) in flora-bearing (FB) BALB/c mice. This antitumor activity was markedly reduced when the germfree (GF) BALB/c mice were used as a host. Histological examination of the injected site revealed vigorous polymorphonuclear leukocyte (PMN) infiltration and tumor cell degeneration at day 1 to 3 postimplantation of WPGMeth A mixture in both FB and GF mice, but later on re-appearance of tumor cell mass was seen in many GF but in only a few FB mice. Similar but somewhat weaker suppressive effects of WPG were seen in FB athymic nu/nu mice in which severe PMN infiltration was also developed. Results indicated that the early inflammatory reaction composed mostly of PMN played a role as the major effector mechanisms in the suppression test, and inferior antitumor activity of PMN from GF mice to that from FB mice was implicated. However, since FB euthymic but not FB nu/nu mice showed development of antitumor immunity in re-implantation, involvement of immunological capacity might have played an additional role in the suppression efficiency.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"241 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114272461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Effect of Yogurt and Yogurt Supplemented with Bifidobacterium and/or Lactulose in Healthy Persons: A Comparative Study 酸奶和添加双歧杆菌和/或乳果糖的酸奶对健康人的影响:一项比较研究

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.10.2_123

T. Tomoda, Y. Nakano, T. Kageyama

{"title":"Effect of Yogurt and Yogurt Supplemented with Bifidobacterium and/or Lactulose in Healthy Persons: A Comparative Study","authors":"T. Tomoda, Y. Nakano, T. Kageyama","doi":"10.12938/BIFIDUS1982.10.2_123","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.10.2_123","url":null,"abstract":"Three types of yogurt supplemented with Bifidobacterium alone, lactulose alone, or both Bifidobacterium and lactulose were fed to healthy persons, who were tested before and after administration. Plain yogurt was fed during a control period. Yogurt containing both Bifidobacterium and lactulose resulted in greater improvement in the form and frequency of feces than the other yogurts. No differences were noted in blood chemistry test results before and after the administration of each type of yogurt. There were no side effects of yogurt administration. The number of Bifidobacterium in the feces increased after the administration of yogurt containing Bifidobacterium and/or lactulose, but there were no differences among the three test yogurts. Not only the administered Bifidobacterium species but also the original Bifidobacterium species was increased by eating Bifidobacterium and lactulose-containing yogurt, but the administered Bifidobacterium species was not increased more than the dominant original species. The ammonia content in the feces decreased more after the administration of Bifidobacteriumand/or lactulose-containing yogurt than after that of plain yogurt but there were no differences among the three test yogurts.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"20 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121011340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Close Association of Streptococcus sanguis Uncommon Serotypes with Behcet's Disease 血链球菌罕见血清型与白塞病密切相关

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.9.1_27

E. Isogai, S. Ohno, K. Takeshi, K. Yoshikawa, T. Tsurumizu, H. Isogai, K. Yokota, S. Kotake, Y. Sasamoto, Hashimoto Takashi, Harumi Shimizu, H. Matsuda, N. Fujii, M. Yamaguchi, K. Oguma

引用次数: 39

Bifidobacteria in Broiler Starter Rations: Factors Affecting Survival 肉仔鸡起始饲料中双歧杆菌:影响生存的因素

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.13.1_17

S. M. Rose, H. Modler, R. Mckellar

引用次数: 1

Nutriology of Bifidobacteria 双歧杆菌营养学

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.2.1_3

Z. Tamura

{"title":"Nutriology of Bifidobacteria","authors":"Z. Tamura","doi":"10.12938/BIFIDUS1982.2.1_3","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.2.1_3","url":null,"abstract":"In those days before 1950, when the manufacture of powdered milk was in its early stages, it was widely recognized that breastfeeding was superior to bottle-feeding for new-born babies, because of a lower frequency of sickness (especially gastro-enteritis), better condition of the patient, and furthermore a lower mortality. There have been reported many hypotheses to explain this observation (Table 1) : Breast milk contains anti-bacterial and anti-viral proteins (secretary IgA), macrophages, lymphoid cells and iron-snatching protein (lactoferrin) ; has no alien substances as antigens; provides mental comfort to babies through close physical contact, and so on. Above all, the difference in intestinal microflora has been considered to be a big factor. In the intestines of breast-fed babies bifidobacteria grow well enough to be predominant over other bacteria (bifidus-flora). On the other hand, in the intestines of bottle-fed babies the number of bifidobacteria decreased and other bacteria such as Escherichia coli dominated in turn (Fig. 1) . Therefore the role of bifidobacteria has been of interest to many investigators such as pediatrists, dieticians, chemists and bacteriologists. These hypotheses are reviewed in references (16, 27, 35 and 53) . The investigators have found the biological activities and roles of bifidobacteria as follows (Table 2) : 1. Bifidobacteria produce acetic acid and lactic acid from sugars. These acids lower pH of a medium and have anti-bacterial effect in acidic condition (2, 8), as shown in Fig. 2. The produced acids also inhibit absorption of ammonia and amines through","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115691513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 80

Metabolism of Drugs by Intestinal Bacteria 肠道细菌对药物的代谢

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.11.1_9

K. Kobashi, T. Akao, M. Hattori, T. Namba

{"title":"Metabolism of Drugs by Intestinal Bacteria","authors":"K. Kobashi, T. Akao, M. Hattori, T. Namba","doi":"10.12938/BIFIDUS1982.11.1_9","DOIUrl":"https://doi.org/10.12938/BIFIDUS1982.11.1_9","url":null,"abstract":"Food and drugs orally administered come inevitably in contact with intestinal bacterial flora in gut. The components in food and drugs are digested in the gut and absorbed from the alimentary tract via portal vein and then metabolized or detoxicated in the liver. Thereafter a part of metabolites are excreted into intestine via bile duct and meet again intestinal bacteria. Not only exogeneous substances but also endogenous ones once excreted in the bile come in contact with intestinal bacterial flora. Drugs administered intravenously, intramuscularly or intracutaneously also have chance to meet with intestinal bacteria when once excreted in the bile. Therefore, microflora in the gastrointestinal flora play significant roles in the enterohepatic circulation of drugs and food components. Accordingly, studies on the metabolism of drugs with intestinal microflora are important for research and development of medicines. However, such metabolic studies are very seldom, compared with the studies with liver, kidney, lung and other organs, because of huge numbers and species of anaerobic bacteria and for lack of biochemical studies on anaerobes. Intestinal bacterial flora are an environmental large factor in the body and almost equal to liver in weight and function, though their activities are mostly unknown. Recently, isolation, cultivation and identification techniques of intestinal bacteria from humans and experimental animals have been established. Therefore, metabolisms of food components and drugs with intestinal bacteria are able to be undertaken, based on biochemical and molecular biological backgrounds.","PeriodicalId":414713,"journal":{"name":"Bifidobacteria and Microflora","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123887754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Stress and Intestinal Flora 应激与肠道菌群

Bifidobacteria and Microflora Pub Date : 1900-01-01 DOI: 10.12938/BIFIDUS1982.8.1_23

Kunio Suzuki, Y. Kodama, T. Mitsuoka

引用次数: 26